Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 153.00 | |
2 mg | In stock | $ 212.00 | |
5 mg | In stock | $ 327.00 | |
10 mg | In stock | $ 497.00 | |
25 mg | In stock | $ 793.00 | |
50 mg | In stock | $ 1,130.00 | |
100 mg | In stock | $ 1,520.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 349.00 |
Description | Saroglitazar (Lipaglyn) is an agonist of PPAR with EC50 values of 0.65 pM and 3 nM for PPARα and PPARγ. |
Targets&IC50 | PPARγ:3 nM (EC50, HepG2 cell), PPARα:0.65 pM (EC50, HepG2 cell) |
In vivo | In db/db mice, Saroglitazar (0.01-3 mg/kg; orally) reduces serum triglycerides, free fatty acids, and glucose in a dose-dependent manner (ED50 = 0.05, 0.19, and 0.19 mg/kg). Saroglitazar (1 mg/kg) significantly reduces serum insulin and AUC-glucose(91%)[3]. |
Synonyms | Lipaglyn |
Molecular Weight | 439.57 |
Formula | C25H29NO4S |
CAS No. | 495399-09-2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.5mg/mL (51.2mM)
You can also refer to dose conversion for different animals. More
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Saroglitazar 495399-09-2 DNA Damage/DNA Repair Metabolism PPAR Lipaglyn inhibitor inhibit