Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
20 mg | In stock | $ 80.00 | |
100 mg | In stock | $ 191.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 45.00 |
Description | Glabridin (KB-289522) may serve as an anti-inflammatory agent in diabetes-related vascular dysfunction, through regulating the synthesis and activity of iNOS under high-glucose levels; may possess a therapeutic effect on metabolic disorders( such as diabetes and hyperglycemia), by modulating glucose metabolism through AMPK in skeletal muscle cells. Glabridin may have potential as a chemopreventive agent against liver Y metastasis, by inhibiting the invasion of human HCC cells. |
Targets&IC50 | α1β1γ2 (GABAA receptor):17.23 μM(EC50), α1β2 (GABAA receptor):9.63 μM(EC50), α1β3γ2 (GABAA receptor):6.83 μM(EC50), α1β2γ2 (GABAA receptor):6.3 μM(EC50) |
Source |
Synonyms | Q-100692, KB-289522, LS-176045 |
Molecular Weight | 324.37 |
Formula | C20H20O4 |
CAS No. | 59870-68-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 58 mg/mL(178.8 mM)
Chloroform, Dichloromethane, Ethyl Acetate, Acetone, etc.: Soluble
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Glabridin 59870-68-7 DNA Damage/DNA Repair Immunology/Inflammation Membrane transporter/Ion channel Metabolism Microbiology/Virology Neuroscience NF-Κb Proteases/Proteasome PPAR GABA Receptor Antibacterial Tyrosinase Reactive Oxygen Species LS 176045 KB289522 Peroxisome proliferator-activated receptors Q 100692 Bacterial inhibit KB 289522 Q100692 Q-100692 KB-289522 LS-176045 LS176045 Inhibitor inhibitor