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Search Results for " al-1 "

272

Compounds

26

Natural Products

1736

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T29809 AL-1 AL 1,AL1
AL-1 is a GLYCOINOSITOL PHOSPHOLIPID MEMBRANE ANCHOR containing ephrin found in developing tectum. It can mediate the bundling of cortical axons and repel the axonal growth of retinal ganglia axons. It exists in a variet...
T21224 (+)-Fluprostenol Fluprostenol, (+)-,Travoprost acid,AL-5848 Prostaglandin Receptor
(+)-Fluprostenol (AL-5848), an analogue of prostaglandin F2 alpha, is a prostaglandin F2α receptor PTGFR agonist and decreases the expression of Oviductal glycoprotein 1 (OVGP1).
T2514 Linifanib ABT-869,RG3635,AL-39324 Apoptosis , c-Fms , VEGFR , FLT , CSF-1R , PDGFR , c-Kit , Autophagy
Linifanib (AL-39324) (ABT-869) is a novel, potent ATP-competitive VEGFR/PDGFR inhibitor for KDR (IC50: 4 nM), CSF-1R (IC50: 3 nM), Flt-1/3 (IC50: 3/4 nM) and PDGFRβ (IC50: 66 nM). Linifanib may exhibit potent antiprolife...
T12628 (R)-MG-132 (S,R,S)-(-)-MG-132,Z-Leu-D-leu-leu-al Proteasome
(R)-MG-132 (Z-Leu-D-leu-leu-al) is the enantiomer of MG-132. (R)-MG-132 stereoisomer is a more potent proteasome inhibitor than MG-132.
T31305 Decanal, 2-ethylidene- 2-Ethylidenedecan-1-al
Decanal, 2-ethylidene- is a biochemical.
T31306 Decanal, 2-methylene- 2-Methylenedecanal,EINECS 244-979-4,2-Methylenedecan-1-al
Decanal, 2-methylene- is a biochemical.
T20984 Lumogallion 4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid Others
Lumogallion (4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid) is an azo reagent used in the determination of metal ions, such as the research of V, Fe, and Al.
T37807 JTV 519 fumarate
Ryanodine receptor (RyR) inhibitor; stabilizes RyR2 in a closed conformation. Exhibits antiarrhythmic and cardioprotective properties in vivo. Hunt et al (2007) K201 (JTV519) suppresses spontaneous Ca2+ release and [3H]r...
T35610 2,5-dimethyl Celecoxib Apoptosis , Wnt/beta-catenin , Prostaglandin Receptor
2,5-dimethyl Celecoxib is a derivative of celecoxib that does not inhibit COX-2 (IC50 = >100 μM).1 It does inhibit microsomal prostaglandin E synthase-1 (mPGES-1) in HeLa cells (IC50 = 15.6 μM) and reduces prostaglandin ...
T36520 COR659 Cannabinoid Receptor , GABA Receptor
COR659 is a GABAB positive allosteric modulator (PAM) . COR659 suppresses alcohol and chocolate self-administration in rats[1]. COR659 apparently exerts its effects via a composite mechanism, including positive allosteri...
T36949 Niaprazine 5-HT Receptor , Adrenergic Receptor , Histamine Receptor
Niaprazine is a histamine H1-receptor antagonist with marked sedative properties. Niaprazine has antihistamine and antiserotonin activities and can be used for sleep disorder research[1][2]. Niaprazine exhibits a low aff...
T37734 AMPA receptor modulator-2 GluR
AMPA receptor modulator-2 (Example 134) is a AMPA receptor modulator, with a pIC50 of 10.1 for TARPγ2 dependent AMPA receptor[1]. pIC50 = -lgIC50. [1]. BERRY CYNTHIA G B (US), et al. AZABENZIMIDAZOLES AND THEIR USE AS AM...
T37197 5-HT1A modulator 2 hydrochloride 5-HT Receptor
5-HT1A modulator 2 hydrochloride, a derivative of 8-OH-DPAT , is a modulator of 5-HT1A with a Ki of 53 nM for 5-HT1A binding[1]. [1]. Naiman, N.,et al. 2-(Alkylamino)tetralin derivatives: interaction with 5-HT1A serotoni...
T38240 2,6-Dichlorodiphenylamine Antibacterial
2,6-Dichlorodiphenylamine is an analogue of Diclofenac Sodium and has anti-Candida albicans activity. Diclofenac Sodium is a potent and nonselective anti-inflammatory agent, acts as a COX inhibitor, with IC50s of 4 and 1...
T36083 DS-7423 PI3K , mTOR
DS-7423 is a dual PI3K and mTOR inhibitor, with IC50 values of 15.6 nM, 34.9 nM for PI3Kα and mTOR, respectively. DS-7423 possesses anti-tumor activity[1][2]. DS-7423 increases TP53 expression, the level of p-TP53 on Ser...
T35856 BMS-986176 AAK1 (AP2 associated kinase 1)
AAK1-IN-1 (example 123) is an AAK1 (adaptor associated kinase 1) inhibitor with an IC50 of 2.2 nM. AAK1-IN-1 can be used for neurodegenerative diseases research[1]. Adaptor associated kinase 1 (AAK1) is a member of the A...
T36674 DMU-212 Apoptosis , ERK
DMU-212 is a methylated derivative of Resveratrol , with antimitotic, anti-proliferative, antioxidant and apoptosis promoting activities. DMU-212 induces mitotic arrest via induction of apoptosis and activation of ERK1/2...
T36682 USP30 inhibitor 18 DUB
USP30 inhibitor 18 is a selective USP30 inhibitor with an IC50 of 0.02 μM. USP30 inhibitor 18 increases protein ubiquitination and accelerates mitophagy[1]. [1]. Arthur F Kluge, et al. Novel highly selective inhibitors o...
T36944 Ara-G Nucleoside Antimetabolite/Analog
Ara-G is an analog of the nucleoside guanosine and an active metabolite of nelarabine .1,2 Ara-G accumulates in T lymphoblasts and malignant T-lymphoid cells, where it is phosphorylated to produce ara-GTP and incorporate...
T35841 5-Benzyloxygramine Dopamine Receptor , 5-HT Receptor
5-Benzyloxygramine is a N protein PPI orthosteric stabilizer that exhibits both antiviral and N-NTD protein-stabilizing activities[1]. 5-benzyloxygramine stabilizes the N-NTD dimers through simultaneous hydrophobic inter...
T38238 2'-Deoxy-2'-fluorocytidine Nucleoside Antimetabolite/Analog , Influenza Virus
2'-Deoxy-2'-fluorocytidine, an nucleoside analog, is a potent inhibitor of Crimean-Congo hemorrhagic fever virus (CCHFV) replication. 2′-deoxy-2′-fluorocytidine can act synergistically with T705 to increase the potency o...
T38361 GSK717 IL Receptor , NOD
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio...
T38050 CP-609754 Transferase
CP-609754 (LNK-754) is a potent and reversible farnesyltransferase inhibitor with potential anticancer activity.The IC50 for inhibiting farnesylation of recombinant human H-Ras is 0.57 ng/mL and recombinant K-Ras is 46 n...
T36968 ARN-21934 Topoisomerase
ARN-21934 is a potent, highly selective, blood-brain barrier (BBB) penetrant inhibitor for human topoisomerase II α over β. ARN-21934 inhibits DNA relaxation with an IC50 of 2 μM as compared to the anticancer agent Etopo...
T35699 Fosetyl-aluminum
0 [1]. Fan Z, Jia S, Ding N, et al. Determination of Fosetyl-Aluminium by Ion-Pair Reversed Phase-High Performance Liquid Chromatography With Evaporative Light Scattering Detection. Se Pu. 2009;27(6):849‐851. [2]. TüRK ...
T38114 AL 8810 ethyl amide
AL 8810 is an 11β-fluoro analog of prostaglandin F2α (PGF2α) which acts as a potent and selective antagonist at the FP receptor. AL 8810 ethyl amide is an analog of AL 8810 in which the C-1 carboxyl group has been modifi...
T39633 Navocaftor GLPG 3067,ABBV-3067
Navocaftor, as a cystic fibrosis transmembrane regulator ( CFTR ), is a protein modulator (US 20200377491 Al, example 1).
T38113 AL 6598
Elevated intraocular pressure (IOP) is an important risk factor in developing glaucoma. Certain prostaglandins such as PGF2α and PGD2, have been shown to reduce IOP. AL 6598 is the isopropyl ester prodrug of AL 6556, a P...
T39266 HTrkA-IN-1
hTrkA-IN-1 is a potent and orally active inhibitor of TrkA kinase with an IC 50 of 1.3 nM, compound 2.hTrkA-IN-1 can be used for the study of inflammatory disease, such as prostatitis, pelvic, et al.
T74487 AL-470
AL-470 demonstrates significant antiviral efficacy, exhibiting EC50 values of 0.27 µM against HIV-1, 0.63 µM against HIV-2, and 0.35 µM against EV-A71, as referenced in [1].
T76210 POT-4 TFA
POT-4 TFA (AL-78898A TFA), a derivative of Compstatin, effectively inhibits the activation of complement factor C3. This compound is utilized in research related to age-related macular degeneration [1] [2].
T38288 Profenofos
Profenofos is an acetylcholinesterase-inhibiting organophosphorus pesticide on field crops, vegetables, and fruit crops [1]. [1]. Madhulika Kushwaha, et al. Kushwaha, M., et al.. Profenofos, an Acetylcholinesterase-Inhib...
T21752 AL 8810
AL-8810 is an 11β-fluoro analog of PGF 2α with selective antagonist effects at the PGF 2α receptor (FP receptor) [1].
T38143 Elaidamide
Elaidamide is a fatty acid amide that has been found in the cerebrospinal fluid of sleep-deprived cats.1 It inhibits rat microsomal epoxide hydrolase (mEH; Ki = 70 nM).2 Elaidamide also inhibits porcine pancreatic and hu...
T61815 AL-GDa62
AL-GDa62, a potential synthetic lethal agent for gastric cancer treatment, demonstrates efficacy with EC50 values of 3.2 μM in MCF10A-WT (wild-type) isogenic mammary epithelial cells and 2 μM in MCF10A-CDH1 -/- cells [1]...
T37640 Trans-2-Hexadecenoyl-L-carnitine
trans-2-Hexadecenoyl-L-carnitine is an endogenous metabolite in urine[1]. [1]. Pengxiang She, et al. Leucine and protein metabolism in obese Zucker rats. PLoS One. 2013;8(3):e59443.
T36380 GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
GLP-1 amide is a peptide hormone cleaved from proglucagon in the pancreas.1,2 Mice lacking the glucagon receptor (Gcgr-/-) have approximately nine-fold higher levels of total GLP-1 amide, including GLP-1 (1-36) amide and...
T37666 Trihydroxycholestanoic Acid Trihydroxycoprostanic Acid
Trihydroxycholestanoic acid is an intermediate in the biosynthesis of cholic acid .1 Elevated plasma levels of trihydroxycholestanoic acid have been found in patients with Zellweger syndrome, a neurological disorder char...
T36851 Peptide5
Connexin43 mimetic peptide. Reduces swelling, astrogliosis, neuroinflammation and neuronal cell death following spinal cord injury ex vivo and in vivo. Exhibits analgesic effects in models of neuropathic pain. O'Carroll ...
T37804 8MDP
Potent equilibrative nucleoside transporter 1 (ENT1) inhibitor (IC50 = 0.43 nM). Inhibits hENT1 and hENT2 uptake of [H3]uridine in K562 cells and K15NTD cells respectively. Lin et al (2011) Design, synthesis, and evaluat...
T36374 Naloxegol (NKTR-118)
Naloxegol (NKTR-118; AZ-13337019) is an opioid-receptor antagonist[1]. [1]. Yoon SC, et al. Naloxegol in opioid-induced constipation: a new paradigm in the treatment of a common problem. Patient Prefer Adherence. 2017 Ju...
T38280 C22 dihydro 1-Deoxyceramide (m18:0/22:0) C22 dihydro 1-Deoxyceramide (m18:0/22:0)
C22 dihydro 1-Deoxyceramide (m18:0/22:0) is a very long-chain atypical ceramide containing a 1-deoxysphinganine backbone. 1-Deoxysphingolipids are formed when serine palmitoyltransferase condenses palmitoyl-CoA with alan...
T37809 Alphitonin
Alphitonin is a flavonoid that has been found in L. leptolepis wood.1 It is also a metabolic intermediate that is formed during the catabolism of quercetin by the human gut bacteria E. ramulus.2,3 |1. Chen, K., Ohmura, W...
T36364 Flutax-2
Green fluorescent taxol derivative. Used for microtubule imaging. Binds microtubules with high affinity (Ka ~ 107M-1). Excitation/emission maximum λ ~ 496/526 nm. Lillo et al (2002) Location and properties of the Tax. bi...
T36995 MRT 68601 hydrochloride
Potent TBK1 (TANK-binding kinase-1) inhibitor (IC50 = 6 nM). Inhibits the formation of autophagosomes in lung cancer cells. Newman et al (2012) TBK1 kinase addiction in lung cancer cells is mediated via autophagy of Tax1...
T35840 4-Amino-6-chloro-1,3-benzenedisulfonamide
4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorot...
T36401 DCVC
DCVC inhibits pathogen-stimulated TNF-α in human extra placental membranes in vitro.Target: TNF-αin vitro: DCVC inhibits pathogen stimulated cytokine release from tissue punch cultures. DCVC (5-50 μM) significantly inhib...
T37887 1-Heptadecanoyl-rac-glycerol
1-Heptadecanoyl-rac-glycerol is a monoacylglycerol that contains heptadecanoic acid at the sn-1 position. It is active against the bacteria E. aerogens, E. cloacae, P. mirabilis, and S. faecalis (MIC = 78 μg/ml for all)....
T38172 RO 5263397 hydrochloride
Potent trace amine 1 (TA1) receptor agonist (EC50 values are 0.12, 35 and 17-85 nM for mouse, rat and human receptors, respectively). Increases wakefulness and reduces REM and NREM sleep duration in wild type mice. Inhib...
T38131 (E)-10-Hydroxynortriptyline
(E)-10-Hydroxynortriptyline (E-10-OH-NT) is a metabolite of Nortriptyline . Nortriptyline is a tricyclic antidepressant and the main active metabolite of Amitriptyline, and is used to relieve the symptoms of depression[1...

Compounds

AL-1
T29809
Synonym: AL 1,AL1
Target:
(+)-Fluprostenol
T21224
Synonym: Fluprostenol, (+)-,Travoprost acid,AL-5848
Target: Prostaglandin Receptor
Linifanib
T2514
Synonym: ABT-869,RG3635,AL-39324
Target: Apoptosis, c-Fms, VEGFR, FLT, CSF-1R, PDGFR, c-Kit, Autophagy
(R)-MG-132
T12628
Synonym: (S,R,S)-(-)-MG-132,Z-Leu-D-leu-leu-al
Target: Proteasome
Decanal, 2-ethylidene-
T31305
Synonym: 2-Ethylidenedecan-1-al
Target:
Decanal, 2-methylene-
T31306
Synonym: 2-Methylenedecanal,EINECS 244-979-4,2-Methylenedecan-1-al
Target:
Lumogallion
T20984
Synonym: 4-Chloro-3-(2,4-dihydroxyphenylazo)-2-hydroxybenzene-1-sulfonic acid
Target: Others
JTV 519 fumarate
T37807
Synonym:
Target:
2,5-dimethyl Celecoxib
T35610
Synonym:
Target: Apoptosis, Wnt/beta-catenin, Prostaglandin Receptor
COR659
T36520
Synonym:
Target: Cannabinoid Receptor, GABA Receptor
Niaprazine
T36949
Synonym:
Target: 5-HT Receptor, Adrenergic Receptor, Histamine Receptor
AMPA receptor modulator-2
T37734
Synonym:
Target: GluR
5-HT1A modulator 2 hydrochloride
T37197
Synonym:
Target: 5-HT Receptor
2,6-Dichlorodiphenylamine
T38240
Synonym:
Target: Antibacterial
DS-7423
T36083
Synonym:
Target: PI3K, mTOR
BMS-986176
T35856
Synonym:
Target: AAK1 (AP2 associated kinase 1)
DMU-212
T36674
Synonym:
Target: Apoptosis, ERK
USP30 inhibitor 18
T36682
Synonym:
Target: DUB
Ara-G
T36944
Synonym:
Target: Nucleoside Antimetabolite/Analog
5-Benzyloxygramine
T35841
Synonym:
Target: Dopamine Receptor, 5-HT Receptor
2'-Deoxy-2'-fluorocytidine
T38238
Synonym:
Target: Nucleoside Antimetabolite/Analog, Influenza Virus
GSK717
T38361
Synonym:
Target: IL Receptor, NOD
CP-609754
T38050
Synonym:
Target: Transferase
ARN-21934
T36968
Synonym:
Target: Topoisomerase
Fosetyl-aluminum
T35699
Synonym:
Target:
AL 8810 ethyl amide
T38114
Synonym:
Target:
Navocaftor
T39633
Synonym: GLPG 3067,ABBV-3067
Target:
AL 6598
T38113
Synonym:
Target:
hTrkA-IN-1
T39266
Synonym:
Target:
AL-470
T74487
Synonym:
Target:
POT-4 TFA
T76210
Synonym:
Target:
Profenofos
T38288
Synonym:
Target:
AL 8810
T21752
Synonym:
Target:
Elaidamide
T38143
Synonym:
Target:
AL-GDa62
T61815
Synonym:
Target:
trans-2-Hexadecenoyl-L-carnitine
T37640
Synonym:
Target:
GLP-1 (1-36) amide (human, rat) (trifluoroacetate salt)
T36380
Synonym:
Target:
Trihydroxycholestanoic Acid
T37666
Synonym: Trihydroxycoprostanic Acid
Target:
Peptide5
T36851
Synonym:
Target:
8MDP
T37804
Synonym:
Target:
Naloxegol (NKTR-118)
T36374
Synonym:
Target:
C22 dihydro 1-Deoxyceramide (m18:0/22:0)
T38280
Synonym: C22 dihydro 1-Deoxyceramide (m18:0/22:0)
Target:
Alphitonin
T37809
Synonym:
Target:
Flutax-2
T36364
Synonym:
Target:
MRT 68601 hydrochloride
T36995
Synonym:
Target:
4-Amino-6-chloro-1,3-benzenedisulfonamide
T35840
Synonym:
Target:
DCVC
T36401
Synonym:
Target:
1-Heptadecanoyl-rac-glycerol
T37887
Synonym:
Target:
RO 5263397 hydrochloride
T38172
Synonym:
Target:
(E)-10-Hydroxynortriptyline
T38131
Synonym:
Target:
1 2 3 4 5 6
Cat No. Product Name Synonyms Targets
T9506 Trans,trans-2,4-Decadienal trans,trans-2,4-Decadien-1-al Others
trans,trans-2,4-Decadienal (trans,trans-2,4-Decadien-1-al) is a product found in Antiaris toxicaria.
T37345 5,7-Dihydroxycoumarin Antibacterial
5,7-Dihydroxycoumarin is a coumarin isolated from the inflorescences of Macaranga triloba. 5,7-Dihydroxycoumarin has antibacterial activities[1][2]. [1]. Ishak Zakaria, et al. Flavonoids with antiplasmodial and cytotoxic...
T37886 1-Heptadecanol Antibacterial
1-Heptadecanol is a long-chain primary alcohol with antibacterial activity from Solena amplexicaulis leaves[1]. [1]. Soumendranath Chatterjee, et al. Antibacterial Activity of Long-Chain Primary Alcohols from Solena ampl...
T37709 2,2,2-Trichloroethanol Potassium Channel , Endogenous Metabolite
2,2,2-Trichloroethanol, the active form of the sedative hypnotic drug chloral hydrate, is an agonist for the nonclassical K2P channels TREK-1 (KCNK2) and TRAAK (KCNK4)[1]. 2,2,2-trichloroethanol activates a nonclassical ...
T78484 Xanthohumol C
Xanthohumol C, a prenylchalcone derived from Humulus lupulus hops [1], exhibits antiproliferative and antiviral properties (Su et al., 2017; Monteiro et al., 2006).
T83391 2-Caren-10-al
2-Carene-10-al is a principal constituent of the essential oil extracted from Cuminum cyminum L. [1].
T83338 3β-Hydroxylanosta-8,24-dien-21-al
3β-Hydroxylanosta-8,24-dien-21-al, a lanostane-type triterpene, exhibits tumor-promoting inhibitory effects by decreasing the incidence of papillomas in mice [1].
T36295 Echistatin TFA
Echistatin TFA, the smallest active RGD protein belonging to the family of disintegrins that are derived from snake venoms, is a potent inhibitor of platelet aggregation. Echistatin is a potent inhibitor of bone resorpti...
T37962 Paeoniflorgenin
Paeoniflorgenin is a deglucosylated metabolite of Paeoniflorin[1]. [1]. Hsiu SL, et, al. A deglucosylated metabolite of paeoniflorin of the root of Paeonia lactiflora and its pharmacokinetics in rats. Planta Med. 2003 De...
T36000 3-Hydroxyterphenyllin
3-Hydroxyterphenyllin is a p-terphenyl fungal metabolite originally isolated from A. candidus that has diverse biological activities, including antioxidant, antiproliferative, antibacterial, and antiviral properties.1,2,...
T37609 (rel)-Asperparaline A
Aspergillimide is a fungal metabolite originally isolated from A. japonicus.1 It reduces nicotinic acetylcholine receptor (nAChR) peak and slowly-desensitizing amplitudes induced by acetylcholine in silkworm (B. mori) la...
T37690 Phenylpyropene A
Phenylpyropene A is a fungal metabolite originally isolated from P. griseofulvum that has enzyme inhibitory and insecticidal activities.1,2,3 It inhibits acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 0.8 μM)....
T38330 Collinin
Collinin is a coumarin that has been found in Z. schinifolium and has diverse biological activities.1,2,3,4 It is active against drug-susceptible and -resistant strains of M. tuberculosis (MIC50s = 3.13-6.25 μg/ml).1 Col...
T36734 Methyl brevifolincarboxylate
Methyl brevifolincarboxylate (Brevifolincarboxylic acid methyl ester) is a potent influenza virus PB2 cap-binding inhibitor. Methyl brevifolincarboxylate exhibits inhibitory activity against influenza virus A/Puerto Rico...
T37451 Stachybotrysin B
Stachybotrysin B is a fungal metabolite originally isolated from S. chartarum and has antiviral and anticancer activities.1,2 It has antiviral activity against HIV in SupT1 cells (IC50 = 19.2 μM).1 Stachybotrysin B is cy...
T36893 4-oxo Withaferin A
4-oxo Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells and carboplatin-resistant A2780 (A2780/CP70) cells (IC50s = 7.3 and <1...
T36329 Terpendole I
Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and ...
T36954 Nemorosone
Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma ce...
T38258 Phanerosporic Acid
Phanerosporic acid is a fungal secondary metabolite originally isolated from P. chrysosporum that has antibacterial activity against B. cereus, B. subtilis, and E. coli and antifungal activity against S. cerevisiae, A. n...
T36179 Aspulvinone O
Aspulvinone O is a fungal metabolite that has been found in P. variotti and has antioxidant and anticancer activities.1,2 It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50 = 11.6 μM).1 Aspulv...
T38038 (-)-Rasfonin
(-)-Rasfonin is a fungal metabolite that has been found in T. terrophilus.1 It inhibits proliferation of mouse splenocytes induced by concanavalin A and LPS (IC50s = 0.7 and 0.5 μg/ml, respectively). References1. Fujimot...
T36738 4′-Hydroxy-2′-methylacetophenone
4′-Hydroxy-2′-methylacetophenone, a red wine aroma compound isolated from the cv. Bobal grape variety, exhibits ciliate toxicity and inhibits T. pyriformis growth with an IC50 of 0.65 mM[1][2].
T35647 4-oxo-27-TBDMS Withaferin A
4-oxo-27-TBDMS Withaferin A is a derivative of the steroidal lactone withaferin A that has anticancer activity.1 It is cytotoxic to A2780 ovarian cancer cells (IC50 = 17 μM) but not to carboplatin-resistant A2780 (A2780/...
T37876 Fengycin
Fengycin, a cyclic lipopeptide, functions as an agricultural fungicide by exhibiting an anti-fungal infection effect through damaging the target's cell membrane[1].
T36950 Rubrofusarin triglucoside
Rubrofusarin triglucoside, a glycoside isolated from Cassia obtusifolia Linn seeds, demonstrates inhibitory activity against human monoamine oxidase A (hMAO-A), exhibiting an IC50 value of 85.5 μM[1].
T38036 Lumisterol
Lumisterol (9β,10α-Ergosterol), a steroid compound and the (9β,10α)-stereoisomer of Ergosterol, serves as a photoprotective agent shielding against UVB-induced DNA damage and exhibits anti-proliferative activities[1].

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01748 Ephrin A5/EFNA5 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Ephrin A5/EFNA5 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.6 kDa and the accession number is O08543-1.
TMPY-01749 Ephrin A5/EFNA5 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
Ephrin A5/EFNA5 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.2 kDa and the accession number is O08543-1.
TMPY-06846 HSP90 alpha Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
HSP90 alpha Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 87.19 kDa and the accession number is NP_032328.2.
TMPY-05169 Peroxiredoxin 2 Protein, Mouse, Recombinant (His) Mouse Baculovirus Insect Cells
Peroxiredoxin 2 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 24.1 kDa and the accession number is Q61171.
TMPJ-00331 IFNAR1 Protein, Rhesus macaque, Recombinant (His) Rhesus HEK293 Cells
Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-...
TMPY-04451 AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&...
TMPY-02501 CD3D & CD3E Heterodimer Protein, Human, Recombinant Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1.
TMPY-03878 Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1.
TMPY-03745 CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) Human HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1.
TMPY-01968 CD32A Protein, Human, Recombinant (167 His, His) Human HEK293 Cells
CD32A Protein, Human, Recombinant (167 His, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22 kDa and the accession number is P12318-1.
TMPY-04824 CTLA-4 Protein, Human, Recombinant Human HEK293 Cells
CTLA-4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 13.5 kDa and the accession number is P16410-1.
TMPY-04632 IL-15 Protein, Human, Recombinant Human E. coli
IL-15 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.8 kDa and the accession number is P40933-1.
TMPY-00414 LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) Human HEK293 Cells
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is A6NI73-1.
TMPY-04529 EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) Human Baculovirus Insect Cells
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 89.1 kDa and the accession number is P00533-1.
TMPY-05201 Siglec-2/CD22 Protein, Human, Recombinant Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 75.2 kDa and the accession number is P20273-1.
TMPY-03782 Albumin Protein, Human, Recombinant Human P. pastoris (Yeast)
Albumin Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 66.4 kDa and the accession number is P02768-1.
TMPY-03956 Fas Ligand Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells su...
TMPY-01578 CD166/ALCAM Protein, Human, Recombinant (His) Human HEK293 Cells
CD166/ALCAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is Q13740-1.
TMPY-05277 IL-4R Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-4R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P24394-1.
TMPY-01920 BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) Human HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293) is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9Y275-1.
TMPY-05220 TSLP Protein, Human, Recombinant (R127A & R130S, His) Human HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16.2 kDa and the accession number is Q969D9-1.
TMPY-01076 Gp130/IL6ST Protein, Human, Recombinant (His & hFc) Human HEK293 Cells
gp130/IL6ST Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 96 kDa and the accession number is P40189-1.
TMPY-00756 FGF-1 Protein, Human, Recombinant Human E. coli
FGF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16 kDa and the accession number is P05230-1.
TMPY-06418 R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) Human HEK293 Cells
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48.01 kDa and the accession number is Q6UXX9-1.
TMPY-05566 Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) Human HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution) is expressed in HEK293 mammalian cells with His tag. The accession number is P20273-1.
TMPY-00322 DEC-205 Protein, Human, Recombinant (His) Human HEK293 Cells
LY75 (Lymphocyte Antigen 75) is a Protein Coding gene. It is broadly expressed in the lymph node, appendix, and other tissues. LY75 knockdown in SKOV3 cells resulted in predominant upregulation of functional pathways imp...
TMPY-02512 Alpha-Synuclein Protein, Human, Recombinant Human E. coli
Alpha-Synuclein Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 14.5 kDa and the accession number is P37840-1.
TMPY-05030 PCDH7 Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cance...
TMPY-06076 LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1.
TMPY-06873 FLT3 Ligand Protein, Human, Recombinant Human E. coli
FLT3 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 17.75 kDa and the accession number is P49771-1.
TMPY-00742 EGFR Protein, Human, Recombinant (His) Human HEK293 Cells
EGFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 69.8 kDa and the accession number is P00533-1.
TMPY-04939 LAG-3 Protein, Human, Recombinant Human HEK293 Cells
LAG-3 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 45.3 kDa and the accession number is P18627-1.
TMPY-01209 IL-7R alpha/CD127 Protein, Human, Recombinant (His) Human HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P16871-1.
TMPY-01964 CD16a Protein, Human, Recombinant (F176V, His) Human HEK293 Cells
The Fc receptor with low affinity for IgG (FCGR3, or CD16) is encoded by 2 nearly identical genes, FCGR3A and FCGR3B, resulting in tissue-specific expression of alternative membrane-anchored isoforms. FCGR3A, it is also ...
TMPY-00694 Carbonic Anhydrase 12 Protein, Human, Recombinant (His) Human HEK293 Cells
Carbonic Anhydrase 12 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.6 kDa and the accession number is O43570-1.
TMPY-03967 BTN3A3 Protein, Human, Recombinant (His) Human HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is O00478-1.
TMPY-06074 B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is A0A2K5U6P5-1.
TMPY-04343 PD-L1 Protein, Human, Recombinant (His) Human HEK293 Cells
PD-L1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1.
TMPY-04153 RNF43 Protein, Human, Recombinant (His) Human HEK293 Cells
RNF43 mutations are frequently detected in colorectal cancer cells and lead to a loss of function of the ubiquitin E3 ligase. The outer mitochondrial membrane 34 (TOMM34) and ring finger protein 43 (RNF43) as highly expr...
TMPY-03273 IL-18 Protein, Mouse, Recombinant Mouse E. coli
IL-18 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is P70380-1.
TMPY-01410 IL-3R alpha/CD123 Protein, Human, Recombinant (His) Human HEK293 Cells
IL-3R alpha/CD123 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P26951-1.
TMPY-05593 IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 42.4 kDa and the accession number is Q9NPH3-1.
TMPY-00820 IgG1 Fc Protein, Human, Recombinant (C103S) Human HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S) is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P01857-1.
TMPY-00686 Complement C2 Protein, Human, Recombinant (His) Human HEK293 Cells
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1.
TMPY-05827 PD-L2 Protein, Human, Recombinant (mFc) Human HEK293 Cells
PD-L2 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 48.93 kDa and the accession number is Q9BQ51-1.
TMPY-05840 IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.56 kDa and the accession number is P59822-1.
TMPY-01862 IL-4 Protein, Human, Recombinant Human E. coli
IL-4 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.1 kDa and the accession number is P05112-1.
TMPY-02591 SDF-1 Protein, Human, Recombinant Human E. coli
SDF-1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 8.6 kDa and the accession number is P48061-1.
TMPY-04104 LIF Protein, Human, Recombinant Human HEK293 Cells
LIF Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.7 kDa and the accession number is P15018-1.
TMPY-00464 M-CSF/CSF1 Protein, Mouse, Recombinant Mouse HEK293 Cells
M-CSF/CSF1 Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26 kDa and the accession number is P07141-1.
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Ephrin A5/EFNA5 Protein, Mouse, Recombinant (His)
TMPY-01748
Species: Mouse
Expression System: HEK293 Cells
Ephrin A5/EFNA5 Protein, Mouse, Recombinant (hFc)
TMPY-01749
Species: Mouse
Expression System: HEK293 Cells
HSP90 alpha Protein, Mouse, Recombinant (His)
TMPY-06846
Species: Mouse
Expression System: Baculovirus Insect Cells
Peroxiredoxin 2 Protein, Mouse, Recombinant (His)
TMPY-05169
Species: Mouse
Expression System: Baculovirus Insect Cells
IFNAR1 Protein, Rhesus macaque, Recombinant (His)
TMPJ-00331
Species: Rhesus
Expression System: HEK293 Cells
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
TMPY-04451
Species: Human
Expression System: Baculovirus Insect Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant
TMPY-02501
Species: Human
Expression System: HEK293 Cells
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
TMPY-03878
Species: Human
Expression System: HEK293 Cells
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
TMPY-03745
Species: Human
Expression System: HEK293 Cells
CD32A Protein, Human, Recombinant (167 His, His)
TMPY-01968
Species: Human
Expression System: HEK293 Cells
CTLA-4 Protein, Human, Recombinant
TMPY-04824
Species: Human
Expression System: HEK293 Cells
IL-15 Protein, Human, Recombinant
TMPY-04632
Species: Human
Expression System: E. coli
LILRA5/CD85f/ILT11 Protein, Human, Recombinant (His)
TMPY-00414
Species: Human
Expression System: HEK293 Cells
EGFR Protein, Human, Recombinant (aa 668-1210, His & GST)
TMPY-04529
Species: Human
Expression System: Baculovirus Insect Cells
Siglec-2/CD22 Protein, Human, Recombinant
TMPY-05201
Species: Human
Expression System: HEK293 Cells
Albumin Protein, Human, Recombinant
TMPY-03782
Species: Human
Expression System: P. pastoris (Yeast)
Fas Ligand Protein, Human, Recombinant (His)
TMPY-03956
Species: Human
Expression System: P. pastoris (Yeast)
CD166/ALCAM Protein, Human, Recombinant (His)
TMPY-01578
Species: Human
Expression System: HEK293 Cells
IL-4R Protein, Human, Recombinant (hFc)
TMPY-05277
Species: Human
Expression System: HEK293 Cells
BAFF/TNFSF13B Protein, Human, Recombinant (HEK293)
TMPY-01920
Species: Human
Expression System: HEK293 Cells
TSLP Protein, Human, Recombinant (R127A & R130S, His)
TMPY-05220
Species: Human
Expression System: HEK293 Cells
gp130/IL6ST Protein, Human, Recombinant (His & hFc)
TMPY-01076
Species: Human
Expression System: HEK293 Cells
FGF-1 Protein, Human, Recombinant
TMPY-00756
Species: Human
Expression System: E. coli
R-Spondin 2/RSPO2 Protein, Human, Recombinant (hFc)
TMPY-06418
Species: Human
Expression System: HEK293 Cells
Siglec-2/CD22 Protein, Human, Recombinant (His, Solution)
TMPY-05566
Species: Human
Expression System: HEK293 Cells
DEC-205 Protein, Human, Recombinant (His)
TMPY-00322
Species: Human
Expression System: HEK293 Cells
Alpha-Synuclein Protein, Human, Recombinant
TMPY-02512
Species: Human
Expression System: E. coli
PCDH7 Protein, Human, Recombinant (His)
TMPY-05030
Species: Human
Expression System: Baculovirus Insect Cells
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
TMPY-06076
Species: Human
Expression System: HEK293 Cells
FLT3 Ligand Protein, Human, Recombinant
TMPY-06873
Species: Human
Expression System: E. coli
EGFR Protein, Human, Recombinant (His)
TMPY-00742
Species: Human
Expression System: HEK293 Cells
LAG-3 Protein, Human, Recombinant
TMPY-04939
Species: Human
Expression System: HEK293 Cells
IL-7R alpha/CD127 Protein, Human, Recombinant (His)
TMPY-01209
Species: Human
Expression System: HEK293 Cells
CD16a Protein, Human, Recombinant (F176V, His)
TMPY-01964
Species: Human
Expression System: HEK293 Cells
Carbonic Anhydrase 12 Protein, Human, Recombinant (His)
TMPY-00694
Species: Human
Expression System: HEK293 Cells
BTN3A3 Protein, Human, Recombinant (His)
TMPY-03967
Species: Human
Expression System: HEK293 Cells
B7-H4 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-06074
Species: Cynomolgus,Rhesus
Expression System: HEK293 Cells
PD-L1 Protein, Human, Recombinant (His)
TMPY-04343
Species: Human
Expression System: HEK293 Cells
RNF43 Protein, Human, Recombinant (His)
TMPY-04153
Species: Human
Expression System: HEK293 Cells
IL-18 Protein, Mouse, Recombinant
TMPY-03273
Species: Mouse
Expression System: E. coli
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
TMPY-01410
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-05593
Species: Human
Expression System: HEK293 Cells
IgG1 Fc Protein, Human, Recombinant (C103S)
TMPY-00820
Species: Human
Expression System: HEK293 Cells
Complement C2 Protein, Human, Recombinant (His)
TMPY-00686
Species: Human
Expression System: HEK293 Cells
PD-L2 Protein, Human, Recombinant (mFc)
TMPY-05827
Species: Human
Expression System: HEK293 Cells
IL-1RAP/IL-1RAcP Protein, Cynomolgus, Recombinant (His)
TMPY-05840
Species: Cynomolgus
Expression System: HEK293 Cells
IL-4 Protein, Human, Recombinant
TMPY-01862
Species: Human
Expression System: E. coli
SDF-1 Protein, Human, Recombinant
TMPY-02591
Species: Human
Expression System: E. coli
LIF Protein, Human, Recombinant
TMPY-04104
Species: Human
Expression System: HEK293 Cells
M-CSF/CSF1 Protein, Mouse, Recombinant
TMPY-00464
Species: Mouse
Expression System: HEK293 Cells
TargetMol