73
14
1737
2
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T15482 | HIF-2α-IN-1 | HIF | |
HIF-2α-IN-1 is a potent HIF-2α inhibitor with IC50 values less than 500 nM. | |||
T67767 | HIF-1 inhibitor-4 | HIF-1 inhibitor-4 | HIF |
HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level. | |||
T36290 | HIF-1 inhibitor-1 | ||
HIF-1 inhibitor-1 is an aryl carboxamide compound and a potent hypoxia-inducible factor 1 (HIF-1) inhibitor with an IC50 of 0.32 μM for the cancer metastasi[1]. [1]. Liu M, et al. Discovery of Novel Aryl Carboxamide Deri... | |||
T39040 | HIF-PHD-IN-1 | ||
HIF-PHD-IN-1 is a pharmacological compound that acts as an orally active inhibitor of the hypoxia-inducible factor prolyl hydroxylase domain (HIF-PHD), displaying an IC50 of 54 nM for hHIF-PHD2. Its potential as a therap... | |||
TP1533 | HIF-1 alpha (556-574) | HIF-1 alpha 556-574 | |
HIF-1 alpha (556-574) is a hypoxia-inducible factor-1 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1subunit is stabilized i... | |||
T9627 | PHD-1-IN-1 | HIF/HIF Prolyl-Hydroxylase | |
PHD-1-IN-1 is a potent inhibitor of hypoxia-inducible factor prolylhydroxylase domain-1 (PHD-1) enzyme(IC50 = 0.034 μM). | |||
T29797 | AKB-6899 | AKB6899 | VEGFR , HIF/HIF Prolyl-Hydroxylase , HIF |
AKB-6899 is an inhibitor of prolyl hydroxylase domain 3 (PHD3) and increases the soluble form of the VEGF receptor (sVEGFR-1) production from GM-CSF-treated macrophages. AKB-6899 leads to stabilization of HIF-2α which in... | |||
TP1546 | HIF-1 alpha (556-574) TFA (1201633-99-9 free base) | HIF-1 alpha (556-574) TFA | |
This is a hypoxia-inducible factor-1 (HIF-1 a) 19-mer fragment. HIF-1 functions as master regulator of response to oxygen homeostasis. Hypoxia-induced gene expression is initiated when HIF-1 subunit is stabilized in resp... | |||
T6823 | E3330 | HIF/HIF Prolyl-Hydroxylase , DNA/RNA Synthesis | |
E3330 is a potent and selective APE1(Ref-1) inhibitor, which suppressed NF-kappa B DNA-binding activity. | |||
T60413 | HIF-IN-1 | HIF | |
HIF-IN-1 is a potent inhibitor of hypoxia-inducible factor (HIF-1), which is associated with tumor and cancer cell proliferation and inhibits HIF-1α protein aggregation. | |||
T71661 | HIF-1α inhibitor-1 | ||
HIF-1α inhibitor-1 is a HIF-1 alpha inhibitor. | |||
T74804 | HIF-1 inhibitor-5 | ||
HIF-1 inhibitor-5 (Compound 16e) is a potent inhibitor of HIF-1, exhibiting an IC50 value of 2.38 μM and demonstrating significant anti-angiogenic potential [1]. | |||
T71659 | Indacaterol acetate | ||
Indacaterol acetate is an ultra-long-acting beta-adrenoceptor agonist. | |||
T61442 | HIF-1/2α-IN-1 | ||
HIF-1/2α-IN-1, an orally active compound, functions as an inhibitor of HIF-2α. Its inhibitory effect on HIF-2α activity is significant, with an IC 50 value of 0.92 μM. Furthermore, HIF-1/2α-IN-1 has the ability to decrea... | |||
T61102 | HIF-1/2α-IN-2 | ||
HIF-1/2α-IN-2 is a potent inhibitor of HIF-1/2α, which effectively reduces the levels of HIF-1/2α. This compound elicits an iron starvation response by specifically targeting ISCA2, a key protein involved in Iron Sulfur ... | |||
T82199 | HIF-1 alpha (556-574) (TFA) | HIF/HIF Prolyl-Hydroxylase | |
HIF-1 alpha (556-574) TFA is a 19-residue fragment of hypoxia-inducible factor-1 (HIF-1), which serves as the master regulator of oxygen homeostasis [1]. | |||
T3494 | LW6 | HIF-1α inhibitor,CAY10585,LW8 | Apoptosis , Dehydrogenase , HIF/HIF Prolyl-Hydroxylase , HIF |
LW6 (HIF-1α inhibitor) is a novel HIF-1 inhibitor. | |||
T5537 | IDF-11774 | HIF/HIF Prolyl-Hydroxylase , HIF | |
IDF-11774 is a HIF-1 inhibitor.It reduces hif-1α HRE luciferase activity (IC50 = 3.65 μM). | |||
T7836 | ML228 | HIF | |
ML228 is a potent the Hypoxia Inducible Factor (HIF) pathway activator with EC50 of 1 μM. ML228 potently activates HIF in vitro as well as its downstream target VEGF. | |||
T15396 | GN44028 | N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine | HIF |
GN44028 (N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine) is a hypoxia-inducible factor inhibitor of (HIF)-1 (IC50: 14 nM). GN44028 inhibits hypoxia-induced HIF-1α transcriptional activity. H... | |||
T22022 | Adaptaquin | HIF | |
Adaptaquin is an inhibitor of the hypoxia-inducing factor prolyl hydroxylase (HIF-PH) [1] [2]. | |||
T75098 | HIF-PHD-IN-3 | Reactive Oxygen Species | |
HIF-PHD-IN-3 is a potent hiPSC-CM cardioprotective scaffold with potential inhibitory effects on HIF-PHD, regulates heme oxygenase-1, and can be used to study anaemia. | |||
T3169 | KC7F2 | HIF/HIF Prolyl-Hydroxylase , HIF | |
KC7F2 is a potent HIF-1 pathway inhibitor with potential anti-cancer activity. | |||
T13050 | SYP-5 | HIF/HIF Prolyl-Hydroxylase , HIF | |
SYP-5 is a novel inhibitor of HIF-1, suppresses tumor cells invasion and angiogenesis. | |||
T2488 | BAY 87-2243 | Ferroptosis , HIF/HIF Prolyl-Hydroxylase , HIF | |
BAY 87-2243 is a potent and selective inhibitor of hypoxia-inducible factor-1 (HIF-1). | |||
T9890 | HIF1-IN-3 | Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]- | HIF |
HIF1-IN-3 (Benzenepropanamide, N-[(8-hydroxy-7-quinolinyl)(4-methoxyphenyl)methyl]-) is an effective inhibitor of HIF-1 (EC50 = 0.9 μM) and can be used in anticancer studies. | |||
T4106 | MK-8617 | MK8617 | HIF/HIF Prolyl-Hydroxylase |
MK-8617 is an orally available HIF PHD1 3 pan-inhibitor, inhibiting PHD1/2/3 (IC50: 1.0/1.0/14 nM). | |||
T36953 | Naphthofluorescein | Naphthafluorescein | HIF |
Naphthofluorescein (Naphthafluorescein) is a Mint3 inhibitor with potential antitumor and anti-inflammatory activities, inhibits the interaction between HIF-1 and Mint3, inhibits Mint3-dependent HIF-1 activity, and inhib... | |||
T4381 | Lificiguat | YC-1 | Others , Guanylate cyclase , HIF |
Lificiguat (YC-1) is an nitric oxide (NO)-independent activator of soluble guanylyl cyclase(sGC) and an inhibitor of Hypoxia-inducible factor-1alpha (HIF-1alpha). | |||
T8973 | HS-1793 | Others | |
HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model | |||
T1823 | IOX2 | IOX 2,JICL38 | HIF/HIF Prolyl-Hydroxylase |
IOX2 (IOX 2) is a selective inhibitor of the Hypoxia Inducible Factor (HIF) Prolyl-Hydroxylases (PHD); active in cells with the IC50 value of 21 nM for PHD2/ELGN-1 and no inhibition at FIH (20uM). | |||
T2283 | PX-12 | IV-2,PX12 | Thioredoxin |
PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor gr... | |||
T0153 | Oltipraz | NSC 347901,RP 35972 | HIF/HIF Prolyl-Hydroxylase , HIV Protease , Reverse Transcriptase , Nrf2 , HIF |
Oltipraz (RP 35972) is a synthetic dithiolethione with potential chemopreventive and anti-angiogenic properties. Oltipraz induces phase II detoxification enzymes, such as glutathione S transferase (GST) and NAD(P)H: quin... | |||
T27866 | LXY6090 | LXY 6090,LXY-6090 | |
LXY6090 is a HIF-1 inhibitor. LXY6090 inhibited the activity of HIF-1 and downregulated the protein level of HIF-1α in breast cancer cells. LXY6090 showed in vivo anticancer efficacy by decreasing the HIF-1α expression i... | |||
T6804 | Chetomin | Chaetomin,NSC289491,BRN0077366 | Apoptosis , HSP , HIF |
Chetomin (BRN0077366) is an inhibitor of HIF-1 by weaken transcription of HIF-1, disrupting the binding of HIF-1α and HIF-2α to p300 at low nanomolar concentrations. | |||
TP2046 | TAT-cyclo-CLLFVY | ||
Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM). Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expressi... | |||
T23894 | CLB-016 | ||
CLB-016 is an inhibitor of hypoxia-inducible factor (HIF)-1. | |||
T61367 | HIF-2α-IN-6 | ||
HIF-2α-IN-6 (117) is a HIF-2α inhibitor [1]. | |||
T61614 | HIF-2α-IN-5 | ||
HIF-2α-IN-5 is a potent HIF-2α inhibitor with an IC 50 of < 50 nM [1]. | |||
T75943 | TAT-cyclo-CLLFVY TFA | ||
TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor specifically targeting HIF-1 heterodimerization to mitigate hypoxia signaling within cancer cells. It effectively disrupts the protein-protein interaction between HIF-1α... | |||
T60398 | Dimethyl-bisphenol A | ||
Dimethyl-bisphenol A (DMBPA) is the potent inhibitor of HIF-1α. Dimethyl-Bisphenol A promotes degradation of HIF-1α protein by dissociating Hsp90 from HIF-1α. Dimethyl-bisphenol A can decrease the expression of Vegfa mRN... | |||
T82198 | HIF-1α-IN-6 | HIF/HIF Prolyl-Hydroxylase | |
HIF-1α-IN-6 (compound 3s) is a potent inhibitor of HIF-1α, demonstrating IC50 values of 0.6 nM and 53.3 nM in MiaPaCa-2 and MDA-MB-231 cells, respectively. It suppresses HIF-1α expression through the reduction of HIF-1α ... | |||
T61161 | HIF-1α-IN-3 | ||
HIF-1α-IN-3, also known as Compound (S)-3f, is a hypoxia-selective inhibitor of HIF-1α. It exhibits potent antiestrogenic activity [1]. | |||
T82595 | DEALA-Hyp-YIPD | ||
DEALA-Hyp-YIPD, an HIF-1α peptide inhibitor, impedes the VHL/HIF-1α interaction with an half-maximal inhibitory concentration (IC50) of 0.91 μM and a dissociation constant (Kd) of 180 nM [1]. | |||
T70903 | KRH102053 | ||
KRH102053 is a HIF-1alpha inhibitor. KRH102053 decreased the protein level of HIF-1alpha and the mRNA levels of HIF-regulated downstream target genes, such as vascular endothelial growth factor, aldolase A, enolase 1 an... | |||
T64310 | KUSC-5001 | ||
KUSC-5001 is a potent inhibitor (IC50: 18 μM) of HIF-1, which has a key role in tumour survival and malignancy. | |||
T60524 | HIF-1α-IN-4 | ||
HIF-1α-IN-4 is an inhibitor of HIF-1α with IC50 of 24 nM in HEK293T cells which has potential antitumor effects. HIF-1α-IN-4 downregulates VEGF and PDK1 mRNA expressions under hypoxia [1]. | |||
T74530 | GEM-5 | ||
GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and c... | |||
T15197 | Echinomycin | Quinomycin A,NSC-13502 | Others |
Echinomycin is a cell-permeable hypoxia-inducible factor-1 (HIF-1) DNA-binding activity inhibitor. Echinomycin selectively inhibits the cancer stem cells (CSCs; IC50: 29.4 pM). | |||
T12547 | Prolyl Hydroxylase inhibitor 1 | Others | |
Prolyl Hydroxylase inhibitor 1 is an orally active inhibitor of hypoxia inducible factor (HIF)-prolyl hydroxylase (PHD) (IC50 of 62.23 nM). |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T1205 | Chloramphenicol | Chlornitromycin,Levomycetin,Chloromycetin | ribosome , HIF/HIF Prolyl-Hydroxylase , Antibacterial , Antibiotic |
Chloramphenicol (Chloromycetin), a broad-spectrum antibiotic, blocks bacterial protein synthesis. | |||
T10233 | Acetylarenobufagin | HIF | |
Acetylarenobufagin is a steroidal hypoxia-inducible factor-1 (HIF-1) modulator. | |||
T3404 | Cucurbitacin B | Cuc B,DATISCACIN,Amarine | Apoptosis , PTEN , Integrin , Endogenous Metabolite , HIF , STAT , Autophagy |
Cucurbitacin B (Cuc B) has profound in vitro and in vivo antiproliferative effects against human pancreatic Y cells. It inhibited AKT signaling activation through up-regulation of PTEN. Cucurbitacin B is an effective inh... | |||
T5429 | Theaflavin 3,3'-digallate | 8-Gingerol,TFDG | Virus Protease , Antioxidant , HIV Protease , HSV |
Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul... | |||
T6429 | Caffeic Acid Phenethyl Ester | Phenylethyl Caffeate,CAPE | Apoptosis , NF-κB |
Caffeic Acid Phenethyl Ester (Phenylethyl Caffeate) (CAPE) inhibits the activation of nuclear transcription factor NF-kappa B and may suppress p70S6K and Akt-driven signaling pathways, with antineoplastic, cytoprotective... | |||
T4S1551 | Cinnamaldehyde | Cinnamic Aldehyde | HIF |
1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express... | |||
T6S0071 | Fraxinellone | HIF/HIF Prolyl-Hydroxylase , STAT , PD-1/PD-L1 | |
1. Fraxinellone significantly reduced weight loss and diarrhea in mice and alleviated the macroscopic and microscopic signs of the disease. 2. Fraxinellone exhibited a variety of insecticidal activities including feeding... | |||
T3S2344 | β,β-Dimethylacrylshikonin | Dimethylacrylshikonin,β, β-Dimethylacrylshikonin | ERK , HIF/HIF Prolyl-Hydroxylase |
1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant... | |||
T75487 | 7-Hydroxyneolamellarin A | ||
7-Hydroxyneolamellarin A, a natural product from the sponge Dendrilla nigra, serves as a potent inhibitor of hypoxia-inducible factor-1α (HIF-1α). It effectively reduces the accumulation of HIF-1α protein and suppresses ... | |||
TN1952 | Moracin P | Others , ROS , HIF | |
Moracin P exhibits potent in vitro inhibitory activity against hypoxia-inducible factor (HIF-1), which is a key mediator during adaptation of cancer cells to tumour hypoxia. | |||
T36439 | Gramicidin A | Antibacterial , HIF , Parasite | |
Gramicidin A is a peptide antibiotic isolated from B. brevis.Gramicidin A is a highly hydrophobic channel-forming ion carrier that forms monovalent cation-permeable channels in artificial membranes.Gramicidin A induces t... | |||
T36749 | Herboxidiene | ||
Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values rangin... | |||
TN4489 | Manassantin A | ERK , cAMP , TNF , NF-κB , MAPK , COX , HIF , Prostaglandin Receptor , JNK , STAT | |
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibitio... | |||
TN1951 | Moracin O | HIF | |
Moracin O shows significant neuroprotective, and analgesic activities, it also has a strong protective influence against doxorubicin-induced cardiomyopathy in H9c2 cells with the EC50 value of 4.5 ± 1.3 μM. Moracin O exh... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01709 | HIF-1 alpha Protein, Human, Recombinant (His) | Human | E. coli |
HIF-1 alpha, also known as HIF1A, contains 1 basic helix-loop-helix (bHLH) domain, 1 PAC (PAS-associated C-terminal) domain, and 2 PAS (PER-ARNT-SIM) domains. It is one of the two subunits of Hypoxia-inducible factor-1 (... | |||
TMPH-01280 | EGLN1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF) alpha proteins. Hydroxylates a specific proline found in each of th... | |||
TMPH-00957 | ARNT Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
ARNT Protein, Human, Recombinant (His) is expressed in Yeast. | |||
TMPY-04671 | MCP-5 Protein, Mouse, Recombinant (His) | Mouse | P. pastoris (Yeast) |
Ccl12 prevented initiation of the reparative response by prolonging inflammation and inhibiting fibroblast conversion to myofibroblasts, resulting in diminished scar formation. Macrophage secretion of Ccl12 directly impa... | |||
TMPH-01512 | HIF1AN Protein, Human, Recombinant (His) | Human | P. pastoris (Yeast) |
Hydroxylates HIF-1 alpha at 'Asn-803' in the C-terminal transactivation domain (CAD). Functions as an oxygen sensor and, under normoxic conditions, the hydroxylation prevents interaction of HIF-1 with transcriptional coa... | |||
TMPY-02376 | BNIP3L Protein, Human, Recombinant | Human | E. coli |
The deletion of BNIP3L results in retention of mitochondria during lens fiber cell remodeling, and that deletion of BNIP3L also results in the retention of endoplasmic reticulum and Golgi apparatus. BNIP3L localizes to t... | |||
TMPY-04451 | AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) | Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&... | |||
TMPY-03878 | Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 | CD3D & CD3E Heterodimer Protein, Human, Recombinant | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03745 | CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) | Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03958 | TGF alpha Protein, Human, Recombinant | Human | E. coli |
The miR-137 served as a tumor suppressor in non-small cell lung cancer (NSCLC) and its suppressive effect is mediated by repressing TGFA expression. TGFA gene expression was significantly higher in tumor tissues compared... | |||
TMPY-04069 | Neurotrophin 3 Protein, Human, Recombinant | Human | E. coli |
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely relate... | |||
TMPY-02907 | FGF-19 Protein, Human, Recombinant | Human | E. coli |
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, inclu... | |||
TMPK-00383 | ACE2/ACEH Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angio... | |||
TMPY-01459 | TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) | Human | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1. | |||
TMPY-01827 | CD30/TNFRSF8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD30/TNFRSF8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P28908-1. | |||
TMPY-01776 | Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Carboxylesterase 2/CES2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.4 kDa and the accession number is O00748-1. | |||
TMPY-02019 | CD59 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD59 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 10.2 kDa and the accession number is P13987-1. | |||
TMPY-01461 | EMAP-II/AIMP1 Protein, Human, Recombinant (His) | Human | E. coli |
EMAP-II/AIMP1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 35 kDa and the accession number is Q12904-1. | |||
TMPY-00972 | FGFR2 Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67.6 kDa and the accession number is P21802-1. | |||
TMPY-01104 | Coagulation factor XI/F11 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Factor XI (plasma thromboplastin antecedent) is a plasma glycoprotein, and a zymogen acting as a serine protease which participates in blood coagulation as a catalyst in the conversion of factor IX to factor IXa in the p... | |||
TMPY-01912 | Cadherin 17/CDH17 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Cadherin 17/CDH17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is Q12864-1. | |||
TMPY-02031 | B7-H3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-02525 | RGMA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
RGMa, also known as RGM domain family, member A, belongs to the RGM (repulsive guidance molecule) family whose members are membrane-associated glycoprotein. RGMa is a glycosylphosphatidylinositol-anchored glycoprotein th... | |||
TMPY-04262 | B7-H3 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
B7-H3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48 kDa and the accession number is Q5ZPR3-1. | |||
TMPY-00915 | Serpin A1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1. | |||
TMPY-02836 | MFGE8 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
MFGE8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q08431-1. | |||
TMPY-01462 | IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is Q14626-1. | |||
TMPK-00176 | BAFF/TNFSF13B Trimer Protein, Human, Recombinant (His & Flag) | Human | HEK293 Cells |
B-cell activating factor (BAFF) also known as tumor necrosis factor ligand superfamily member 13B is a protein that in humans is encoded by the TNFSF13B gene.BAFF is a cytokine that belongs to the tumor necrosis factor (... | |||
TMPY-02034 | Siglec-2/CD22 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Siglec-2/CD22 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.6 kDa and the accession number is P20273-1. | |||
TMPY-02794 | TLR2 Protein, Human, Recombinant (aa 1-587, His) | Human | Baculovirus Insect Cells |
TLR2 Protein, Human, Recombinant (aa 1-587, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 65.5 kDa and the accession number is O60603-1. | |||
TMPY-04799 | IFNAR2 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1. | |||
TMPY-02647 | IFNAR1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1. | |||
TMPY-04826 | LILRB5/CD85c Protein, Human, Recombinant (His) | Human | HEK293 Cells |
A genetic variant in LILRB5 (leukocyte immunoglobulin-like receptor subfamily-B) (rs12975366: T > C: Asp247Gly) has been reported to be associated with lower creatine phosphokinase (CK) and lactate dehydrogenase (LDH) le... | |||
TMPY-00740 | SDF-1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SDF-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.2 kDa and the accession number is P48061-1. | |||
TMPY-04698 | HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His) | Human | HEK293 Cells |
HER2/ERBB2 Protein, Human, Recombinant (aa 489-630, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number is P04626-1. | |||
TMPY-00203 | LOXL2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Lysyl oxidase homolog 2, also known as Lysyl oxidase-like protein 2, Lysyl oxidase-related protein 2, Lysyl oxidase-related protein WS9-14 and LOXL2, is a secreted protein that belongs to the lysyl oxidase family. LOXL2 ... | |||
TMPK-00305 | TGFBR1 Protein, Human, Recombinant (mFc & Avi) | Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup... | |||
TMPY-01938 | CD98 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD98 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 49.2 kDa and the accession number is P08195-1. | |||
TMPY-01023 | CD38 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CD38 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.3 kDa and the accession number is P28907-1. | |||
TMPK-01074 | CD163 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
The hemoglobin (Hb) scavenger receptor, CD163, is a macrophage-specific protein and the upregulated expression of this receptor is one of the major changes in the macrophage switch to alternative activated phenotypes in ... | |||
TMPY-01226 | CD4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CD4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.8 kDa and the accession number is P06332-1. | |||
TMPY-01305 | OSMR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
OSMR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.6 kDa and the accession number is Q99650-1. | |||
TMPY-04753 | IRE1 Protein, Human, Recombinant (aa 465-977) | Human | Baculovirus Insect Cells |
IRE1 Protein, Human, Recombinant (aa 465-977) is expressed in Baculovirus insect cells. The predicted molecular weight is 58.3 kDa and the accession number is O75460-1. | |||
TMPY-03407 | NQO1 Protein, Human, Recombinant (His) | Human | E. coli |
NQO1 gene is a member of the NAD(P)H dehydrogenase (quinone) family and encodes a cytoplasmic 2-electron reductase. NQO1 forms homodimers and reduces quinones to hydroquinones. NQO1's enzymatic activity prevents the one-... | |||
TMPY-05526 | Siglec-15 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Siglec-15 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.7 kDa and the accession number is Q6ZMC9-1. | |||
TMPY-04949 | PD-L1 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
PD-L1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is Q9NZQ7-1. | |||
TMPY-03630 | MZB1/PERP1 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MZB1/PERP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.4 kDa and the accession number is Q8WU39-1. | |||
TMPY-02327 | HGF Protein, Human, Recombinant | Human | CHO Cells |
HGF Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 79.7 kDa and the accession number is P14210-1. | |||
TMPY-01608 | Decorin Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Decorin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is P07585-1. | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L8500 | HIF-1 Signaling Pathway Compound Library | 1336 compounds | |
A unique collection of 1336 HIF-1 related small chemicals can be used for drug discovery in ischemic disease and cancer and related mechanism studies; | |||
L2130 | Anti-Cancer Metabolism Compound Library | 1268 compounds | |
A unique collection of 1268 cancer cellular metabolism related compounds for cancer research and high throughput screening (HTS) and high content screening (HCS); |