Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-κB activation, and improvements in the antioxidant and anti-inflammatory status.Manassantin A represents a potential therapeutic approach for the treatment of airway allergic-inflammatory diseases. Manassantin A inhibits cAMP-induced melanin production by down-regulating the gene expressions of MITF and tyrosinase in melanocytes.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
10 mg | Inquiry | $ 1,280.00 | |
1 mL * 10 mM (in DMSO) | Inquiry | $ 1,300.00 |
Description | Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effects might be associated with COX/PGE2 stimulation, inhibition of iNOS production and NF-κB activation, and improvements in the antioxidant and anti-inflammatory status.Manassantin A represents a potential therapeutic approach for the treatment of airway allergic-inflammatory diseases. Manassantin A inhibits cAMP-induced melanin production by down-regulating the gene expressions of MITF and tyrosinase in melanocytes. |
Source |
Molecular Weight | 732.867 |
Formula | C42H52O11 |
CAS No. | 88497-87-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Manassantin A 88497-87-4 Angiogenesis Apoptosis Chromatin/Epigenetic GPCR/G Protein Immunology/Inflammation JAK/STAT signaling MAPK Neuroscience NF-Κb Stem Cells NF-κB TNF ERK cAMP COX HIF STAT JNK Prostaglandin Receptor inhibitor inhibit