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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TP1497L | Mast Cell Degranulating Peptide HR-2 acetate | Mast Cell Degranulating Peptide HR-2 acetate(80388-04-1 free base) | Others |
Mast Cell Degranulating Peptide HR-2 acetate from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom. | |||
TP1568 | Mast cell degranulating peptide (28-49) | ||
Mast cell degranulating peptide (28-49) is a bee venom depolarizer that can improve the cGMP content of cerebellum tablets in mice. | |||
TP1497 | Mast Cell Degranulating Peptide HR-2 | ||
Peptide from giant hornet Vespa orientalis that has biological effects similar to mast cell degranulating peptide from bee venom. | |||
T9689 | M4205 | c-Kit | |
M4205 is an inhibitor of c-Kit exhibiting high activity on c-Kit mutations in exons 11, 13, 17. | |||
T0118 | Mizolastine | SL 850324 | Histamine Receptor |
Mizolastine (SL 850324) (IC50= 47 nM) is a histamine H1-receptor antagonist.It is used in the treatment of allergic reactions such as hay fever (seasonal allergic rhinitis), hives. | |||
T6488 | Epinastine hydrochloride | Alesion,Epinastine HCl,WAL-801CL HCl,Elestat | 5-HT Receptor , Histamine Receptor |
Epinastine hydrochloride (WAL-801CL HCl) is an antihistamine and mast cell stabilizer that is used in eye drops to treat allergic conjunctivitis. | |||
T2648 | Pimecrolimus | SDZ-ASM 981,ASM 981 | Others |
Pimecrolimus (SDZ-ASM 981), a calcineurin inhibitor immunosuppressant, binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction cascade mediated by calcineuri... | |||
T0994 | Ketotifen fumarate | HC 20511 fumarate | PDE , Histamine Receptor |
Ketotifen fumarate (HC 20511 fumarate) is a cycloheptathiophene blocker of histamine H1 receptors and release of inflammatory mediators. | |||
T15259 | Evatanepag | CP-533536 free acid | Prostaglandin Receptor |
Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered l... | |||
T3148 | MK-571 sodium | L-660711 (sodium salt),L-660711 sodium salt,Verlukast sodium,L-660711,MK571,MK-571 sodium salt,Propanoic acid | Leukotriene Receptor , LTR |
MK-571 sodium (L-660711 sodium salt) is a selective, orally active antagonist of the CysLT1 receptor. MK-571 sodium is a multidrug resistance protein-2 (ABCC2, Mrp2) inhibitor used to demonstrate the role of Mrp2 in the ... | |||
T22256 | C-Kit-IN-5-1 | 3-(2-Aminoquinazolin-6-yl)-4-methyl-1-(4-(oxazol-2-yl)phenyl)pyridin-2(1H)-one,AMG-25,3-(2-aminoquinazolin-6-yl)-4-methyl-1-[4-(1,3-oxazol-2-yl)phenyl]pyridin-2-one | c-Kit |
c-Kit-IN-5-1 (AMG-25) is a novel selective and potent c-Kit inhibitor. | |||
T6885 | Marimastat | BB2516,KB-R8898,TA2516 | MMP |
Marimastat (BB2516) (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM)and MMP-7 (IC50=13 nM). | |||
T30190 | Ataquimast | Others | |
Ataquimast is used in curing advanced receptor-positive breast cancer. | |||
T67959 | Pirodomast | Thrombin , Serine Protease | |
Pirodomast is a thromboxane A (TXA2) synthase inhibitor. Pirodomast inhibits leukotriene (LT) D4, C4, E4 formation and thromboxane B2 (TXB2) activity, but is weakly or ineffectively antagonistic to guinea pig bronchospas... | |||
T19966 | Clemastine | HS-592,Mecloprodin,Meclastin,HS592,HS 592 | Histamine Receptor |
Clemastine (Meclastin) is an antagonist of the H1 receptor and exhibits anti-inflammatory effects. | |||
TP1386L1 | Mastoparan acetate(72093-21-1 free base) | Others | |
Mastoparan acetate is a peptide toxin from wasp venom. It has the chemical structure Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2. | |||
T0147 | Clemastine fumarate | HS-592 (fumarate),Meclastine fumarate,Meclastine (fumarate) | Autophagy , Histamine Receptor |
Clemastine fumarate (Meclastine (fumarate)) is a synthetic ethanolamine with anticholinergic, sedative, and histamine H1 antagonistic properties. | |||
T35859 | Aldumastat | GLPG1972,S201086,G504572 | Others |
Aldumastat (GLPG1972) is a highly potent, specific and orally active inhibitor of ADAMTS-5.Aldumastat is used for the study of osteoarthritis of the knee. | |||
T83168 | Aderamastat | FP-025 | MMP |
Aderamastat (FP-025) is an orally active inhibitor of matrix metalloproteinase 12 (MMP-12), utilized in the research of conditions such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis [1]. | |||
T6011 | Batimastat | BB94 | MMP |
Batimastat (BB94) (BB-94) is an effective, broad-spectrum matrix metalloprotease (MMP) inhibitor. Batimastat induces extracellular matrix degradation and inhibits angiogenesis, tumor growth and invasion, and metastasis. | |||
T5449 | Bamaquimast | F 10126,L 0042 | Proton pump |
Bamaquimast (L 0042) is an inhibitor of proton pump | |||
T2743 | Ilomastat | Galardin,GM6001 | MMP |
Ilomastat (GM6001) (GM6001, Galardin) is a broad spectrum matrix metalloprotease (MMP) inhibitor. | |||
T68128 | Picumast | ||
Picumast shows antiallergic activity and can be utilized in the treatment of asthma. Picumast may be used in the treatment of therapeutic allergic airway diseases. | |||
T16986 | Tanomastat | BAY 12-9566 | MMP |
Tanomastat is an orally bioavailable and non-peptidic biphenyl matrix metalloproteinases inhibitor. For MMP-2, MMP-3, MMP-9, MMP-13 the Ki values are 11, 143, 301, and 1470 nM respectively. | |||
T24817 | Otaplimastat | J3.046.690J,SP8203,SP-8203,SP 8203 | |
SP-8203 is a reactive oxygen species inhibitor and superoxide dismutase stimulant. | |||
T80322 | Mastoparan B | ||
Mastoparan B, an antimicrobial peptide originating from the hornet Vespa, induces morphological changes in red blood cells, transforming their typical discoid shape into a serrated configuration [1]. | |||
TP1386 | Mastoparan | ||
Mastoparan is a peptide toxin from wasp venom. It has the chemical structure Ile-Asn-Leu-Lys-Ala-Leu-Ala-Ala-Leu-Ala-Lys-Lys-Ile-Leu-NH2. | |||
T80047 | Polistes mastoparan | ||
Polistes mastoparan, an antimicrobial peptide, enhances K+ efflux in S. aureus cells and reduces cell viability, exhibiting an EC50 of 5 μM [1]. | |||
T81180 | Semastatin-5B | ||
Semastatin-5B, an anti-angiogenic peptide composed of 17 amino acids, can be derived from proteins featuring type I thrombospondin motifs [1]. | |||
T69716 | Solimastat | ||
Solimastat is a novel oral, broad-spectrum matrix metalloproteinase inhibitor (MMPI), being >10-fold more active than marimastat in inhibiting the processing of cell-bound TNF-alpha. | |||
T30164 | Asobamast | ||
Asobamast is a biochemical. | |||
T71488 | Cremastranone | ||
Cremastranone is a natural antiangiogenic homoisoflavanone. Cremastranone inhibits the proliferation, migration, and tube formation ability of human retinal microvascular endothelial cells. | |||
T131480 | Masticadienonic acid | ||
Masticadienonic acid is a useful organic compound for research related to life sciences and the catalog number is T131480. | |||
T81851 | MASTL-IN-1 | ||
MASTL-IN-1 is a potent inhibitor of microtubule-associated serine/threonine kinase-like (MASTL), which plays a role in cell proliferation, migration, and invasion, thereby holding promise in cancer research [1]. | |||
T12539L | Prinomastat | KB-R9896,AG3340 | MMP |
Prinomastat inhibits MMP-2, MMP-3 and MMP-9 (Kis: 0.05 nM, 0.3 nM and 0.26 nM, respectively). Prinomastat crosses the blood-brain barrier. It also has antitumor activity. Prinomastat is a broad-spectrum, potent, orally a... | |||
T10461 | Batimastat sodium salt | BB-94 sodium salt | MMP |
Batimastat (BB-94) sodium salt is a broad-spectrum MMP inhibitor (IC50s: 3, 4, 4, 6, and 20 nM for MMP-1, MMP-2, MMP-9, MMP-7, and MMP-3). | |||
T76094 | Mastoparan X | ||
Mastoparan X, a tetradecapeptide derived from wasp venom, functions as a GTP-binding regulatory protein (G protein)-activating peptide. It directly activates G proteins coupled to phospholipase C, inducing secretion in v... | |||
T124674 | 3β,5α-Dihydroxystigmastan-6-one | ||
3β,5α-Dihydroxystigmastan-6-one is a useful organic compound for research related to life sciences and the catalog number is T124674. | |||
T31794 | FireMaster 695 | 1,2-Bis(pentabromophenoxy)ethane,Decabromo diphenyl ethyl,Ethylene bis(pentabromophenoxide),Decabromodiphenoxyethane | |
FireMaster 695 is a biochemical. | |||
T33215 | Masticadienediol | ||
Masticadienediol is a tetracyclic triterpene. | |||
T125511 | Stigmast-7-en-3-ol | ||
Stigmast-7-en-3-ol is a useful organic compound for research related to life sciences and the catalog number is T125511. | |||
T124943 | 6-Hydroxystigmasta-4,22-dien-3-one | ||
6-Hydroxystigmasta-4,22-dien-3-one is a useful organic compound for research related to life sciences and the catalog number is T124943. | |||
T124266 | 6α-Hydroxystigmast-4-en-3-one | ||
6α-Hydroxystigmast-4-en-3-one is a useful organic compound for research related to life sciences and the catalog number is T124266. | |||
T125590 | Clemastanin A | ||
Clemastanin A is a useful organic compound for research related to life sciences and the catalog number is T125590. | |||
T62090 | (Rac)-Tanomastat | ||
Rac)-Tanomastat ((Rac)-BAY 12-9566) is a racemate of Tanomastat. Tanomastat (BAY 12-9566) is an orally active, zinc carboxy-containing inhibitor of non-peptide biphenyl matrix metalloproteinases (MMPs) that inhibits MMP-... | |||
T69301 | Picumast dihydrochloride | ||
Picumast dihydrochloride is a prophylactically active anti-allergic compound which combines inhibition of mediator release and action. The activity profile of PDH differs clearly from that of known prophylactic anti-alle... | |||
T81850 | MASTL-IN-2 | ||
MASTL-IN-2 is a potent inhibitor of microtubule-associated serine/threonine kinase-like (MASTL). It demonstrates notable efficacy in suppressing the proliferation of human epithelial MIA PaCa cancer cells, exhibiting an ... | |||
T22255 | Amastatin | Others | |
Amastatin is a non-toxic inhibitor of aminopeptidase A and leucine aminopeptidase, and its Ki for aminopeptidase A is 1 µM . | |||
T10817 | Cipemastat | Ro 32-3555 | Others |
Cipemastat is a competitive inhibitor of human collagenases 1, 2, and 3 (Kis: 3.0, 4.4, and 3.4 nM). | |||
T12539 | Prinomastat hydrochloride | KB-R9896 hydrochloride,AG3340 hydrochloride | MMP |
Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN6737 | (25R)-Spirost-4-ene-3,12-dione | Others | |
(25R)-Spirost-4-ene-3,12-dione is a natural product. | |||
T2967 | Stigmasterol | Stigmasterin,beta-Stigmasterol | MMP , Endogenous Metabolite |
Stigmasterol (Stigmasterin) is found in the fats and oils of soybean, calabar bean and rape seed, as well as several other vegetables, legumes, nuts, seeds, and unpasteurized milk. Stigmasterol has been focused on the ch... | |||
T16943 | Stigmastanol | Endogenous Metabolite | |
Stigmastanol is a phytosterol. | |||
TN5066 | Stigmasta-5,8-dien-3-ol | Others | |
Stigmasta-5,8-dien-3-ol is a natural product for research related to life sciences. The catalog number is TN5066 and the CAS number is 570-72-9. | |||
TN3172 | 6beta-Hydroxystigmast-4-en-3-one | Others | |
6beta-Hydroxystigmast-4-en-3-one is a natural product for research related to life sciences. The catalog number is TN3172 and the CAS number is 36450-02-9. | |||
TN5062 | Stigmast-4-ene-3,6-dione | ||
Stigmast-4-ene-3,6-dione has anti-inflammatory and anti-allergic properties. | |||
T81086 | Stigmast-5-ene-3,7-dione | ||
Stigmast-5-ene-3,7-dione (Compound 10), isolated from the roots, leaves, and twigs of Penianthus longifolius [1], is a naturally occurring chemical entity. | |||
TN5064 | Stigmasta-4,22-dien-3-one | Others | |
Stigmasta-4,22-dien-3-one has antioxidant activity. | |||
T83543 | (E)-Masticadienonic acid | ||
(E)-Masticadienonic acid, a triterpene, can be isolated from Vallesia glabra [1]. | |||
TN5068 | Stigmastane-3,6-diol | Others | |
Stigmastane-3 beta, 6 alpha-diol and stigmastane-3 beta, 6 beta-diol possess marked inhibitory activity against 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice, the 50% inhibitory dose is 0.5--1.0... | |||
TN3254 | 7alpha-Hydroxystigmasterol | Others | |
7alpha-Hydroxystigmasterol is a natural product of Xanthium, Asteraceae. The catalog number is TN3254 and the CAS number is 64998-19-2. 7alpha-Hydroxystigmasterol can be used as a reference standard. | |||
T83339 | 3β-(Acetyloxy)stigmast-5-en-7-one | ||
3β-(Acetyloxy)stigmast-5-en-7-one exhibits anti-complement activity [1]. | |||
TN1327 | 7,22,25-Stigmastatrienol | Others | |
7,22,25-Stigmastatrienol is a natural product | |||
TN5067 | Stigmastane-3,5,6-triol | Antifection | |
Stigmastane-3,5,6-triol and derivatives could be used for preparing antiviral medicine. | |||
T75638 | Himastatin | ||
Himastatin, a dimeric cyclohexadepsipeptide featuring piperazic acid and a distinctive central aromatic core [1], is an antitumor antibiotic synthesized by a strain of S. hygroscopicus sp. | |||
T81085 | Stigmasta-3,5-dien-7-one | ||
Stigmasta-3,5-dien-7-one is a steroid derivative sourced from Harrisonia abyssinica [1]. | |||
TN2908 | 3,7,16-Trihydroxystigmast-5-ene | Others | |
3,7,16-Trihydroxystigmast-5-ene is a natural product for research related to life sciences. The catalog number is TN2908 and the CAS number is 289056-24-2. | |||
TN5063 | Stigmasta-4,22,25-trien-3-one | Others | |
Stigmasta-4,22,25-trien-3-one is a natural product from Callicarpa giraldiana. | |||
TN2238 | Stigmasterol glucoside | Others | |
Stigmasterol glucoside, a constituent of Adenanthera pavonina seed and leaf, may be a plant anticancer agent. | |||
TN5294 | Stigmasta-4,22-diene-3β,6β-diol | ||
Stigmasta-4,22-diene-3β,6β-diol is a natural product for research related to life sciences. The catalog number is TN5294 and the CAS number is 167958-89-6. | |||
TN5069 | (5α)-Stigmastane-3,6-dione | Stigmastane-3,6-dione | |
Stigmastane-3,6-dione has anti-inflammatory activity. 5 alpha-Stigmastane-3,6-dione shows antifeedant activity against bell weevils. | |||
TN6801 | Stigmastadienone | ||
Stigmastadienone is a natural product. | |||
TN4505 | Masticadienolic acid | Others | |
Masticadienolic acid is a specific competitive inhibitor of secreted phospholipase A2, it not only protects the active site histidine from alkylation but also inhibits the action of secreted from pancreas, synovial fluid... | |||
T83259 | 6β-Hydroxystigmasta-4,22-dien-3-one | ||
6β-Hydroxystigmasta-4,22-dien-3-one is a steroidal compound that can be isolated from the plant Hedychium coronarium [1]. | |||
TN5285 | Stigmast-4-ene-3β,6β-diol | ||
Stigmast-4-ene-3beta,6beta-diol possesses marked inhibitory activity against 12-O- -tetradecanoylphorbol-13-acetate (TPA)-induced inflammation in mice. | |||
TN1506 | Clemastanin B | Influenza Virus | |
Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment. | |||
TN5065 | Stigmasta-4,25-dien-3-one | Others | |
Stigmasta-4,25-dien-3-one is a natural product for research related to life sciences. The catalog number is TN5065 and the CAS number is 848669-08-9. | |||
T6926 | Palmitoylethanolamide | Mackpeart DR 14V,N-palmitoylethanolamine,Loramine P 256,Impulsin,AM 3112,Palmidrol | Influenza Virus , Endogenous Metabolite , PPAR |
Palmitoylethanolamide (Impulsin) is an endogenously fatty acid amide. It has a role as an anti-inflammatory drug, an antihypertensive agent, a neuroprotective agent and an anticonvulsant.Upon administration, palmitoyleth... | |||
T4946 | (+)-Columbianetin acetate | COLUMBIANETIN ACETATE | Others |
(+)-Columbianetin acetate (COLUMBIANETIN ACETATE) may be helpful in regulating mast cell-mediated allergic inflammatory responses.The absorption of (+)-Columbianetin acetate is a passive diffusion process without pH-depe... | |||
T5S1286 | (+)-Columbianetin | (S)-Columbianetin,Columbianetin | Antifungal |
(+)-Columbianetin ((S)-Columbianetin) is a new phytoalexin associated with celery (Apium graveolens) resistance to pathogens during storage, it also has antifungal activity. (+)-Columbianetin has anti-inflammatory effect... | |||
TN1516 | Cnidicin | NOS , NO Synthase | |
Cnidicin has anti-allergic and anti-inflammatory activity, it inhibits the degranulation of mast cell and the NO generation in RAW 264.7 cells(IC50 value, 7.5 microM). Cnidicin exhibits a significant inhibition on the pr... | |||
T6943 | Picropodophyllin | AXL1717,Picropodophyllin (PPP),Picropodophyllotoxin,PPP | Apoptosis , IGF-1R |
Picropodophyllin (Picropodophyllin (PPP)) (PPP) is a specific IGF-1R inhibitor (IC50: 1 nM). Picropodophyllin specifically inhibits the activity and downregulates the cellular expression of IGF1R without interfering with... | |||
T4S0797 | Berberine | Berberin,Umbellatine | Reactive Oxygen Species , Topoisomerase , Endogenous Metabolite , Antibacterial , Antibiotic , Autophagy |
1. Berberine (Umbellatine) is a potent oral hypoglycemic agent with beneficial effects on lipid metabolism. 2. Berberine may as a broad-spectrum anti-microbial medicine, a complementary therapeutic agent for HIV/AIDS. 3.... | |||
T5S2343 | Acetylshikonin | Acetyl shikonin | Others , P450 , AChE |
1. Acetylshikonin exhibits weak cytotoxicity against human umbilical vein endothelial cells (HUVECs) with IC5 of over 2 microM, exhibits the antiangiogenic and antitumorigenic effects by suppressing proliferation and ang... | |||
T3S0027 | Picropodophyllotoxin | AXL 1717,Picropodophyllin | IGF-1R |
Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti... | |||
TN3062 | 4'-O-Methylnyasol | Histamine Receptor | |
4'-O-Methylnyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. | |||
TN3864 | Dihydroresveratrol 3-O-glucoside | Others | |
Dihydroresveratrol 3-O-glucoside is a natural product fonud in the leaves of Camellia sinensis var. assamica (J.W. Mast.) Kitam. | |||
TN2895 | 3,5-Dicaffeoyl-epi-quinic acid | IL Receptor , p38 MAPK , TNF , Caspase , JNK , Histamine Receptor | |
3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases. | |||
T25687 | Leukotriene C4 | LTC4,Leukotriene C | |
Leukotriene C4 is the conjugation product of Leukotriene A4 and glutathione. It is the major arachidonic acid metabolite in human mast cells, macrophages, and antigen-sensitized lung tissue. It stimulates mucus secretion... | |||
TN5279 | Zeorin | ATPase , Calcium Channel , Antifection , Histamine Receptor | |
Zeorin shows strong inhibition activity against bacteria and fungi. It markedly exhibits inhibitory activity on histamine release from mast cell induced by DNP24-BSA, it shows potent inhibitory effect by 40% decrease of ... | |||
TN6539 | Pd-C-II | ||
Pd-C-II has anti-inflammation activity, it can inhibit TNF-α production and iNOS protein expression and inhibit COX-2 protein expression in LPS-stimulated RAW 264.7 cells. Pd-C-II inhibits anaphylactic mediator release f... | |||
T83329 | 4,7-Didehydroneophysalin B | ||
4,7-Didehydroneophysalin B, a flavonoid exhibiting cholinesterase inhibitory properties, is derived from the Physalis alkekengi L. var. franchetii (Mast.) Makino plant, from which it can be isolated and purified. | |||
T80998 | Thapsigargicin | Thapsigargicine | |
Thapsigargicin (Thapsigargicine) acts as an activator for mast cells and leukocytes, prompting histamine release from rat peritoneal mast cells and human basophil leukocytes. Additionally, it elevates cytoplasmic free ca... | |||
TN5647 | Confluentin | ||
Confluentin has antimicrobial activity against the gram-positive bacteria.Confluentin significantly inhibits compound 48/80-induced histamine release from rat peritoneal mast cells. Confluentin also shows weak cytotoxici... | |||
TN6667 | Spinacetin | ||
Spinacetin has anti-inflammatory effects, it weakly inhibited nitric oxide production and reduced prostaglandin E2 levels to different extents. It shows the activities in preventing inflammatory processes, which might be... | |||
TN4392 | Koaburaside | IL Receptor , TNF , Influenza Virus | |
Koaburaside exhibits antioxidant activity with an IC50 value of 9.0μM, it shows weak inhibitory activity against influenza A neuraminidase. Koaburaside may have anti-allergic inflammatory activity, it can suppress histam... | |||
TN3325 | 9-O-Feruloyl-5,5'-dimethoxylariciresinol | IL Receptor , TNF | |
(+)-9'-O-trans-feruloyl-5,5'-dimethoxylariciresinol may have anti-allergic inflammatory effect, it can inhibit release of histamine from mast cells. It shows cytotoxicity against a small panel of human tumor cell lines, ... | |||
TN1009 | Epimagnolin B | NF-κB , NO Synthase , Prostaglandin Receptor | |
Epimagnolin B has anti-inflammatory activity, it can inhibit the production of NO and PGE(2) and the expression of respective enzyme iNOS and COX-2 through the suppression of I-kappaB-alpha degradation and nuclear transl... | |||
TN4683 | Nyasol | ERK , IL Receptor , IκB/IKK , NOS , NF-κB , Akt , Antifection | |
Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antif... | |||
T37272 | 9(S),12(S),13(S)-TriHOME | ||
9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble ... | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-01470 | SCF Protein, Human, Recombinant | Human | E.coli |
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultu... | |||
TMPJ-00166 | SCF Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gameto... | |||
TMPJ-00051 | IL-3 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit... | |||
TMPH-02581 | Chymase 1 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Major secreted protease of mast cells with suspected roles in vasoactive peptide generation, extracellular matrix degradation, and regulation of gland secretion. | |||
TMPY-04139 | MCEMP1 Protein, Human, Recombinant (mFc) | Human | HEK293 |
MCEMP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 with mFc tag. The predicted molecular weight is 36 kDa. Accession number: A0A384NYE9 | |||
TMPY-01057 | SPG21 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Spastic paraplegia 21 (SPG21), also known as acid Cluster Protein 33 (ACP33) and Mast syndrome protein, is a member of the AB hydrolase superfamily. Human SPG21 is a 38 amino acid residue protein widely expressed in all ... | |||
TMPH-02499 | Allergin-1 Protein, Mouse, Recombinant (His & Myc) | Mouse | E. coli |
Immunoglobulin-like receptor which plays an inhibitory role in degranulation of mast cells. Negatively regulates IgE-mediated mast cell activation and suppresses the type I immediate hypersensitivity reaction. | |||
TMPY-02752 | SPG21 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
Spastic paraplegia 21 (SPG21), also known as acid Cluster Protein 33 (ACP33) and Mast syndrome protein, is a member of the AB hydrolase superfamily. Human SPG21 is a 38 amino acid residue protein widely expressed in all ... | |||
TMPY-02574 | Chymase 1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
The STR polymorphism in the CMA1 gene is associated with asthma and that this association is even stronger with atopic asthma. CMA1 and IL-4 in atopic asthma and for IL-4 in atopy in general. The local angiotensin II sys... | |||
TMPY-01027 | Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I... | |||
TMPH-00486 | Chymase Protein, Canine, Recombinant (His & SUMO) | Canine | E. coli |
Chymase Protein, Canine, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-01641 | CPA3 Protein, Human, Recombinant (His) | Human | E. coli |
CPA3 Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPY-04969 | Allergin 1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
MILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to ... | |||
TMPY-04963 | Allergin 1 Protein, Human, Recombinant (His) | Human | HEK293 |
MILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to ... | |||
TMPY-05061 | Allergin 1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
MILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to ... | |||
TMPJ-00897 | TPSB2 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Tryptase beta-2(Tpsb2), also known as Mast cell protease 6(mMCP-6), belongs to the peptidase S1 family and Tryptase subfamily. Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled... | |||
TMPJ-00894 | SCF Protein, Rat, Recombinant (His) | Rat | E. coli |
Stem cell factor (SCF), is the ligand for the receptor-type protein-tyrosine kinase KIT. It plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesi... | |||
TMPJ-00895 | SCF Protein, Rat, Recombinant (HEK293, His) | Rat | Human Cells |
SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, ... | |||
TMPJ-00402 | CD117 Protein, Human, Recombinant (hFc) | Human | Human Cells |
C-Kit/SCF R is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to ... | |||
TMPY-05685 | Human mastadenovirus E (HAdV-E) fiber Protein (His) | HAdV-E | Baculovirus-Insect Cells |
Human mastadenovirus E (HAdV-E) fiber Protein (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 46.56 kDa. Accession number: Q6H1A8 | |||
TMPH-01685 | MAST4 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
MAST4 Protein, Human, Recombinant (His & Myc) is expressed in E. coli. | |||
TMPY-05690 | Human mastadenovirus B (HAdV-B) encapsidation protein IVa2 Protein (His) | HAdV-B | Baculovirus-Insect Cells |
Human mastadenovirus B (HAdV-B) encapsidation protein IVa2 Protein (His) is expressed in Baculovirus-Insect Cells with His tag. The predicted molecular weight is 52.06 kDa. Accession number: YP_002213830.1 | |||
TMPY-05655 | C-Kit Protein, Rhesus, Recombinant (hFc) | Rhesus | HEK293 |
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr... | |||
TMPJ-01204 | TPSAB1 Protein, Human, Recombinant (His) | Human | Human Cells |
Tryptases are serine proteases with trypsin-like specificity. Together with chymases and Cathepsin G, tryptases are important players in mast cell mediation of inflammatory and allergic responses. Tryptase alpha/beta-1(T... | |||
TMPY-01845 | IL-10 Protein, Human, Recombinant (His) | Human | HEK293 |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-05064 | IL-10 Protein, Mouse, Recombinant | Mouse | E. coli |
IL-10 is an anti-inflammatory cytokine that belongs to the IL-10 family. It is produced by a variety of cell lines, including T-cells, macrophages, mast cells, and other cell types, while it is produced primarily by mono... | |||
TMPY-04051 | C-Kit Protein, Human, Recombinant (hFc) | Human | HEK293 |
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr... | |||
TMPY-05084 | Fc epsilon RI Protein, Human, Recombinant | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-03054 | Fc epsilon RI Protein, Human, Recombinant (His) | Human | HEK293 |
FcERI, also known as FCER1A, is the alpha subunit of the immunoglobulin epsilon receptor (IgE receptor). IgE receptor is a high affinity IgE receptor which plays a central role in allergic disease, coupling allergen and ... | |||
TMPY-01802 | C-Kit Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr... | |||
TMPY-01935 | C-Kit Protein, Human, Recombinant (His) | Human | HEK293 |
C-Kit is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). c-Kit contains 5 Ig-like C2-type (immunoglobulin-like) domains and 1 protein kinase domain. It belongs to the pr... | |||
TMPY-02105 | SCF Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod... | |||
TMPY-02170 | SCF Protein, Human, Recombinant (aa 1-189, His) | Human | Baculovirus-Insect Cells |
Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod... | |||
TMPJ-01465 | GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) | Human | E.coli |
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of... | |||
TMPJ-00850 | ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) | Mouse | Human Cells |
ST2, also called IL-1 R4, is an Interleukin-1 receptor family glycoprotein that plays a role in Th2 immune responses. ST2 is expressed on the surface of mast cells, activated Th2 cells, macrophages, and cardiac myocytes.... | |||
TMPY-05576 | IL-5 Protein, Human, Recombinant (His) | Human | HEK293 |
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo... | |||
TMPY-02554 | IL-5 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo... | |||
TMPY-02022 | CD40 Ligand Protein, Human, Recombinant (hFc) | Human | HEK293 |
The cluster of differentiation (CD) system is commonly used as cell markers in immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th... | |||
TMPY-03915 | IL-5 Protein, Human, Recombinant | Human | E. coli |
Interleukin 5 (IL-5) is a member of the interleukin family with a length of 115 amino acids. Interleukins are a group of cytokines (secreted proteins/signaling molecules) that were first seen to be expressed by white blo... | |||
TMPY-02632 | SIRP alpha Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPJ-00042 | TSLP Protein, Human, Recombinant | Human | E. coli |
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci... | |||
TMPY-06052 | SIRP alpha V2 Protein, Human, Recombinant (His) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-01573 | SIRP alpha Protein, Human, Recombinant (G75A, His) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-05841 | SIRP alpha Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPY-06051 | SIRP alpha Protein, Human, Recombinant (hFc) | Human | HEK293 |
Tyrosine-protein phosphatase non-receptor type substrate 1, also known as SHP substrate 1, Inhibitory receptor SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Macrophage fusion receptor, CD172 antig... | |||
TMPK-00559 | CD300A Protein, Cynomolgus, Recombinant (Avi) | Cynomolgus | HEK293 |
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.C... | |||
TMPK-00212 | CD300A Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.C... | |||
TMPH-02257 | TPSB2 Protein, Human, Recombinant (His & Myc) | Human | Yeast |
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. | |||
TMPH-02258 | TPSB2 Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Tryptase is the major neutral protease present in mast cells and is secreted upon the coupled activation-degranulation response of this cell type. May play a role in innate immunity. | |||
TMPK-00560 | CD300A Protein, Cynomolgus, Recombinant (Avi), Biotinylated | Cynomolgus | HEK293 |
CD300a is an inhibitory receptor for mast cells and eosinophils in allergic inflammation (AI); however, the spatiotemporal expression of CD300a and its potential roles in the resolution of AI are still to be determined.C... | |||
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Cat No. | Product Name | ||
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L3300 | Histamine & Melatonin Receptor-Targeted Compound Library | 153 compounds | |
A unique collection of 153 compounds targeting histaminergic receptor and melatonin receptor for high throughput screening (HTS) and high content screening (HCS) for new drugs; |