Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 6-8 weeks | $ 1,070.00 | |
50 mg | 6-8 weeks | $ 1,390.00 | |
100 mg | 6-8 weeks | $ 2,120.00 |
Description | Prinomastat hydrochloride is a orally active inhibitor of metalloproteinase (MMP)(MMP-1, MMP-3 and MMP-9 with IC50s of 79, 6.3 and 5.0 nM , respectively),with Antitumor avtivity. |
Targets&IC50 | MMP1:79 nM, MMP2:0.05 nM (ki), MMP13:0.3 nM (ki), MMP13:6.3 nM, MMP9:0.26 nM (ki), MMP9:5 nM |
In vitro | Prinomastat inhibits Wnt1-induced MMP-3 production. Reversal of Wnt1-induced EMT and β-catenin transcriptional activity by Prinomastat[1]. |
In vivo | Prinomastat has good tumour growth inhibition, with a short T1/2 of 1.6 hours[1]. |
Synonyms | KB-R9896 hydrochloride, AG3340 hydrochloride |
Molecular Weight | 459.97 |
Formula | C18H22ClN3O5S2 |
CAS No. | 1435779-45-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 100 mg/mL (217.41 mM), Sonification is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Prinomastat hydrochloride 1435779-45-5 Proteases/Proteasome MMP KB-R9896 hydrochloride KB-R-9896 Hydrochloride Prinomastat Hydrochloride AG3340 hydrochloride AG-3340 Hydrochloride AG3340 Hydrochloride KB-R 9896 Hydrochloride AG 3340 Hydrochloride KB-R9896 Hydrochloride inhibitor inhibit