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Clemastanin B

Catalog No. TN1506 CAS 112747-98-5

Clemastanin B has <a href="/target/Antioxidant" style="display: inline; color: #c13a36">Antioxidant</a> and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Clemastanin B, CAS 112747-98-5

Pack Size	Availability	Price/USD	Quantity
10 mg	Inquiry	$ 510.00
1 mL * 10 mM (in DMSO)	Inquiry	$ 520.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Clemastanin B has antioxidant and anti-inflammatory activities, it exerts its anti-influenza activity by inhibiting the virus multiplication, prophylaxsis and blocking the virus attachment.

In vitro

The experiment consisted of four parts: therapeutic action, prophylaxsis action, inhibition of virus attachment, and direct virucidal action. Cytopathic effect (CPE) and 3-(4,5-Dimethylthiazol-2-yI)-2,5-diphenyltetrazolium (MTT) were used to assess antiviral activity. CB, epigoitrin, PEP and PEP ALK OA fractions from Banlangen (Radix Isatidis) extract significantly increased the viability of MDCK cells pre-infected with the virus compared with the virus control group in all the dilutions (P < 0.01). Pretreated with either pure compounds or chemical fractions of Banlangen (Radix Isatidis) extract in all the dilutions significantly improved the viability of MDCK cells (P < 0.01). The inhibition of virus absorption to the host cells by CB, epigoitrin and PEP was in a dose dependent manner.

Molecular Weight	684.68
Formula	C32H44O16
CAS No.	112747-98-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Antiviral activities against influenza virus (FM1) of bioactive fractions and representative compounds extracted from Banlangen (Radix Isatidis).J Tradit Chin Med. 2016 Jun;36(3):369-76.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Clemastanin B 112747-98-5 Microbiology/Virology Influenza Virus Inhibitor inhibitor inhibit

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