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Evatanepag

Catalog No. T15259 CAS 223488-57-1

Synonyms: CP-533536 free acid

Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered locally as a single dose in rat models of fracture healing.

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Evatanepag, CAS 223488-57-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 80.00
5 mg	In stock	$ 197.00
10 mg	In stock	$ 313.00
25 mg	In stock	$ 533.00
50 mg	In stock	$ 768.00
100 mg	In stock	$ 1,080.00
1 mL * 10 mM (in DMSO)	In stock	$ 217.00

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Purity: 99.68%

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Description	Evatanepag (CP-533536 free acid) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.CP-533536 demonstrated the ability to heal fractures when administered locally as a single dose in rat models of fracture healing.
In vitro	CP-533536 is a potent and selective EP2agonist. CP-533536 shows the ability to heal fractures when administered locally as a single dose in rat models of fracture healing s excellent in vitro potency and it also displays against EP2 and selectivity against a broad panel of other targets.

Synonyms	CP-533536 free acid
Molecular Weight	468.57
Formula	C25H28N2O5S
CAS No.	223488-57-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 32 mg/mL (68.29 mM)

References and Literature

1. Cameron KO, et al. Discovery of CP-533536: an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation. Bioorg Med Chem Lett. 2009 Apr 1;19(7):2075-8.

Related compound libraries

This product is contained In the following compound libraries：

GPCR Compound Library Bioactive Compounds Library Max NO PAINS Compound Library Immunology/Inflammation Compound Library Bioactive Compound Library ReFRAME Related Library

Related Products

Related compounds with same targets

Epimagnolin B Capillarisin Treprostinil diethanolamine 15-keto Prostaglandin F2α NTP42 4-O-Cinnamoylquinic acid Angoroside C Pectolinarin

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Keywords

Evatanepag 223488-57-1 GPCR/G Protein Immunology/Inflammation Prostaglandin Receptor HDM asthma CP533536 mast cell CP-533536 CP 533536 bone Inhibitor CP-533536 free acid Fracture healing allergy inflammation inhibit inhibitor

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