Search Result

Search Results for " vegf-a "

Targets

Compounds

Natural Products

263

Recombinant Proteins

Libraries

Cat No.	Product Name	Synonyms	Targets
T4288	HVEGF-IN-1		VEGFR
	hVEGF-IN-1 inhibits human VEGF-A translation and has antitumor activity.		VEGFR
T11153	EG00229		Others
	EG00229 is a neuropilin 1 (NRP1) receptor antagonist that selectively inhibits the binding of VEGF-A to the NRP1 b1 domain, achieving this inhibition with an IC50 value of 3 μM. It does not affect the binding of VEGF-A t...		Others
T4554	AG 1406		VEGFR
	AG 1406 is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2.		VEGFR
T9928	Ranibizumab		VEGFR
	Ranibizumab is a humanized monoclonal antibody fragment designed to target and inhibit vascular endothelial growth factor (VEGF), including VEGF110, VEGF121, and VEGF165. Ranibizumab's ability to selectively target and n...		VEGFR
T37424	CAY10781	CAY10781	Others
	CAY10781 is an inhibitor of the protein-protein interaction between neuropilin-1 (NRP-1) and VEGF-A.1It inhibits the interaction by 43% when used at a concentration of 12.5 μM. CAY10781 also inhibits VEGF-A-induced phosp...		Others
T19832	Acriflavine Hydrochloride	Acriflavine HCl	HIF
	Acriflavine Hydrochloride (Acriflavine HCl) is a HIF-1α inhibitor. It acts by targeting HIF-1α-mediated pathways and decreasing the level of PGK1, VEGF, and HIF-1α in vitro and in vivo.		HIF
T9929	Ramucirumab		VEGFR
	Ramucirumab is a human VEGFR-2 antagonist for the treatment of solid tumors.		VEGFR
T8973	HS-1793		Others
	HS-1793, a resveratrol analogue, downregulates the expression of hypoxia-induced HIF-1 and VEGF and inhibits tumor growth of human breast cancer cells in a nude mouse xenograft model		Others
T3567	SU 4942		Others
	SU-4942 is a modulator of tyrosine kinase signaling. SU-4942 has inhibitory effects on endothelial cell mitosis induced by VEGF and endothelial cell growth factor (ECGF).		Others
T61349	HIF-1α-IN-2		HIF
	HIF-1α-IN-2 is a novel and highly potent HIF-1α inhibitor with anticancer and antitumor activity that inhibits the expression of HIF-1α and VEGF in a dose-dependent manner and inhibits cell migration.		HIF
T9904	Bevacizumab		VEGFR
	Bevacizumab, a humanized monoclonal antibody, specifically and with high affinity binds to all isoforms of VEGF-A.		VEGFR
T8496	MAZ51		Apoptosis , VEGFR
	MAZ51 is a VEGFR-3 (Flt-4) tyrosine kinase inhibitor.		Apoptosis , VEGFR
T7836	ML228		HIF
	ML228 is a potent the Hypoxia Inducible Factor (HIF) pathway activator with EC50 of 1 μM. ML228 potently activates HIF in vitro as well as its downstream target VEGF.		HIF
TP1886L1	NoxA1ds acetate(1435893-78-9 free base)		NADPH-oxidase
	NoxA1ds acetate is a potent and selective NADPH oxidase 1 (NOX1) inhibitor (IC50 : 20 nM). Exhibits selectivity for NOX1 over NOX2, NOX4, NOX5 and xanthine oxidase. Inhibits NOX1-derived O2- production in HT-29 human col...		NADPH-oxidase
T3560	Desmethylanethol trithione	ADT-OH	VEGFR , Akt
	Desmethylanethol trithione (ADT-OH) is a derivative of anethole dithiolethione (ADT) and synthetic hydrogen sulfide (H2S) donor. In the in vitro glucose-oxygen deprivation (OGD) model, Desmethylanethol trithione markedly...		VEGFR , Akt
T67836	AT-533		HSP , HSV
	AT-533 is a potent inhibitor of Hsp90 and HSV. AT-533 blocks the HIF-1α/VEGF/VEGFR-2 signaling pathway, leading to suppress tumor growth and angiogenesis. AT-533 also inhibits the activation of the downstream pathways, i...		HSP , HSV
T12574	PTC299	Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate	VEGFR , Dehydrogenase
	PTC299 ((4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate) is an orally active inhibitor of VEGFA mRNA translation and selectively inhibits VEGF protein synthesis at t...		VEGFR , Dehydrogenase
T3599	BFH772	BFH-722	VEGFR
	BFH772, a structure analogue of BAW2881, is a potent and selective VEGF inhibitor. BFH772 is highly effective at targeting VEGFR2 kinase with an IC50 value of 3 nM. BFH772 inhibits the ligand induced autophosphorylation ...		VEGFR
T76756	Parsatuzumab	RG 7414,Anti-EGFL7,MEGF0444A,MEGF-0444A,RO-5490248,M0444A	VEGFR
	Parsatuzumab (RG 7414) is a humanized monoclonal antibody targeting EGFL7, which is also used as an immunomodulator.Parsatuzumab selectively inhibits the interaction between EGFL7 and endothelial cells, and has an inhibi...		VEGFR
T72924	VEGFR-3-IN-1		VEGFR
	VEGFR-3-IN-1 is a novel potent and selective VEGFR3 inhibitor with an IC50 of 110.4 nM.VEGFR-3-IN-1 possesses antitumor activity, inactivates the VEGFR3 signaling pathway, and inhibits the proliferation and migration of ...		VEGFR
T33701	NM-3	NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3	Apoptosis , Reactive Oxygen Species
	NM-3 is an orally available anti-angiogenic inhibitor with anti-tumour activity.NM-3 is used as a radiation modulator in vitro and in vivo.NM-3 inhibits vascular endothelial growth factor (VEGF), thereby inhibiting the p...		Apoptosis , Reactive Oxygen Species
T3980	Su1498	Tyrphostin SU 1498,AG 1498	VEGFR
	Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1,...		VEGFR
T2064	Semaxinib	SU5416	VEGFR
	Semaxinib (SU5416) is a potent and selective VEGFR2 inhibitor (IC50: 1.23 μM), 20-fold more selective for VEGFR than PDGFRβ, lack of activity against InsR, EGFR, and FGFR. Semaxanib reversibly inhibits ATP binding to the...		VEGFR
T2283	PX-12	IV-2,PX12	Thioredoxin
	PX-12 (PX12) (1-methylpropyl 2-imidazolyl disulfide) is a small-molecule inhibitor of Trx-1 (thioredoxin-1), stimulates apoptosis, down-regulates HIF-1α and vascular endothelial growth factor (VEGF) and inhibits tumor gr...		Thioredoxin
T2160	Suramin Sodium Salt	BAY-205,Suramin hexasodium salt,NF-060	Apoptosis , Phosphatase , SARS-CoV , Sirtuin , Reverse Transcriptase , Topoisomerase , Parasite
	Suramin Sodium Salt (BAY-205) is a sodium salt form of suramin, a polysulphonated naphthylurea with potential antineoplastic activity. Suramin blocks the binding of various growth factors, including insulin-like growth f...
T4425	JK-P3		VEGFR
	JK-P3 is a pyrazole-based inhibitor of VEGFR-2 (IC50: 7.8 μM). JK-P3 inhibits FGFR 1/3 kinase activity in vitro, but has no effect on FGFR signaling in cell-based assays. The compound blocks wound healing and tube format...		VEGFR
T68039	Cep-5214
	CEP-5214 is a potent, low-nanomolar pan inhibitor of human VEGF-R tyrosine kinases, displaying IC50 values of 16,8, and 4 nM for VEGF-R1/FLT-1, VEGF-R2/KDR, and VEGF-R3/FLT-4, respectively, with cellular activity equival...
T28760	Setafrastat
	Setafrastat is a vascular endothelial growth factor (VEGF) promotor and rotamase inhibitor.
T71944	FGF/PDGF/VEGF RTK Inhibitor
	FGF/PDGF/VEGF RTK Inhibitor is a potent, reversible, atp-competitive inhibitor against pdgfrβ, fgfr-1, and vegfr-2 (ic50 = 20, 90, and 240 nm, respectively) and effectively suppresses vegf-stimulated proliferation of h...
T78009	ATWLPPR Peptide
	ATWLPPR Peptide is a biologically active peptide functioning as a specific antagonist to VEGFR2/KDR. It binds to VEGFR2 (KDR/flk), thereby completely inhibiting VEGF binding to KDR and blocking VEGF-induced angiogenesis ...
T2500L	Cediranib maleate	AZD-2171,Recentin,AZD2171,AZD2171 maleate,AZD 2171
	Cediranib is a potent and selective inhibitor of VEGF with antineoplastic activities. It inhibits all three vascular endothelial growth factor receptor (VEGF-1,-2,-3) tyrosine kinases, thereby blocking VEGF-signaling, an...
T80287	KLTWQELYQLKYKGI		VEGFR
	KLTWQELYQLKYKGI (QK) is a VEGF-mimicking peptide that competes with VEGF by binding to its receptors. It facilitates the healing of gastric ulcers in rodents through both oral and systemic administration and has demonstr...		VEGFR
T77046	Ivonescimab
	Ivonescimab (AK112) is a PD-1/VEGF bispecific antibody, utilized in cancer research [1] [2] [3].
T22259	AMG-Tie2-1	AMG-Tie2	Others
	AMG-Tie2-1 is a dual inhibitor of VEGF receptor 2 (VEGFR2) and tunica interna endothelial cell kinase 2 (Tie2).		Others
T28960	Thaspine HCl	Thaspine,Thaspine HCl, NSC 135784,NSC-135784,NSC135784
	Thaspine is a potent topoisomerase IB inhibitor. Taspine downregulates VEGF expression and inhibits proliferation of vascular endothelial cells through PI3 kinase and MAP kinase signaling pathways.
T27622	IPS-05002
	IPS-05002 is an integrin a5β1 antagonist. IPS-05002 inhibited VEGF-stimulated human umbilical vein endothelial cell (HUVEC) proliferation, adhesion, and migration in a dose-dependent manner. IPS-05002 is a potent inhibit...
T40037	Timtraxanib	AVI-3207
	Timtraxanib (AVI-3207) is a potent and specific inhibitor of VEGF-2, offering great potential for investigating senile macular degeneration.
T76574	Arginyl-Glutamine
	Arginyl-Glutamine, a dipeptide, has been shown to reduce VEGF levels and inhibit retinal neovascularization in a mouse model of oxygen-induced retinopathy [1].
T30107	Apratyramide
	Apratyramide is a marine-derived peptidic stimulator of VEGF-A and other growth factors with potential application in wound healing.
T76837	Vanucizumab
	Vanucizumab, a pioneering bispecific IgG1-like monoclonal antibody, concurrently inhibits the interaction of VEGF-A and angiopoietin-2 (Ang-2) with their respective receptors, exerting antiangiogenic and anticancer prope...
T24534	Nimolinone	D9,11-Nimolinone
	Nimolinone is presented in EENL. EENL by regulating the genes involved in cellular development and cell death functions could control cell proliferation, attenuate the stimulatory effects of VEGF, and exert antiangiogen...
T78253	Faricimab	RG7716	VEGFR
	Faricimab, a bispecific antibody, simultaneously targets angiopoietin-2 and vascular endothelial growth factor-A (VEGF-A), and is utilized in research on diabetic macular edema (DME) [1].		VEGFR
T75156L	Bevasiranib sodium
	Bevasiranib sodium, an siRNA compound, targets and silences the genes responsible for producing vascular endothelial growth factor (VEGF). The suppression of VEGF, a critical factor in the development of choroidal neo-va...
T10273	AhR modulator-1		Others
	AhR modulator-1 is a selective and orally active aryl hydrocarbon receptor (AhR) modulator. It inhibits metastasis, in part, by inhibiting prostatic VEGF production prior to tumor formation. It also possesses anti-estrog...		Others
T28788	SK-216	SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor
	SK-216 is a specific PAI-1 inhibitor. SK-216 reduced the extent of angiogenesis in the tumors and inhibited VEGF-induced migration and tube formation by human umbilical vein endothelial cells in vitro. SK-216 reduced the...
T80152	Protein LMWP		VEGFR
	Protein LMWP, a cell-penetrating peptide, exhibits inhibitory activity against vascular endothelial growth factor (VEGF), and is utilized in cancer research for its potential to impede tumor proliferation [1].		VEGFR
T80593	Brolucizumab	DLX1008,ESBA 1008,RTH258	VEGFR
	Brolucizumab (DLX1008) is a single-chain anti-VEGF-A antibody fragment exhibiting low picomolar affinity (K D = 1.05 pM), utilized for cancer research [1] [2].		VEGFR
T68935	BMS-645737
	BMS-645737 is an inhibitor of vascular endothelial growth factor (VEGF) receptor-2 and fibroblast growth factor (FGF) receptor-1. BMS-646737 has anti-angiogenic activity and was evaluated in nonclinical studies as a trea...
T27033	CKD-712	CKD 712,CKD712
	CKD-712 is a nuclear factor NF-kappa B inhibitor. CKD-712 suppressed MMP-9, but not MMP-2 and other NF-κB-regulated proteins involved in cancer metastasis such as VEGF. CKD-712 induced cell cycle arrest at G2M phase by s...
T21795	CRT5
	CRT5, a pyrazine benzamide, is a potent and selective PKD inhibitor. The VEGF-induced phosphorylation of three PKD substrates (IC50s = 1, 2, and 1.5 nM for PKD1, PKD2, and PKD3, respectively), histone deacetylase 5, CREB...

Compounds

Acriflavine Hydrochloride

T19832

Synonym: Acriflavine HCl

Target: Apoptosis, VEGFR

NoxA1ds acetate(1435893-78-9 free base)

TP1886L1

Synonym:

Target: NADPH-oxidase

Desmethylanethol trithione

Synonym: Emvododstat,(4-chlorophenyl) (1S)-6-chloro-1-(4-methoxyphenyl)-1,3,4,9-tetrahydropyrido[3,4-b]indole-2-carboxylate

Target: VEGFR, Dehydrogenase

Synonym: RG 7414,Anti-EGFL7,MEGF0444A,MEGF-0444A,RO-5490248,M0444A

Synonym: NM-3,isocoumarin,NM 3,Isocoumarin NM-3,NM3

Target: Apoptosis, Reactive Oxygen Species

Su1498

T3980

Synonym: Tyrphostin SU 1498,AG 1498

Synonym: BAY-205,Suramin hexasodium salt,NF-060

Target: Apoptosis, Phosphatase, SARS-CoV, Sirtuin, Reverse Transcriptase, Topoisomerase, Parasite

FGF/PDGF/VEGF RTK Inhibitor

Synonym: AZD-2171,Recentin,AZD2171,AZD2171 maleate,AZD 2171

Synonym: Thaspine,Thaspine HCl, NSC 135784,NSC-135784,NSC135784

Synonym: D9,11-Nimolinone

Synonym: SK216.Plasminogen activator inhibitor-1 (PAI-1) inhibitor

Synonym: DLX1008,ESBA 1008,RTH258

Synonym: CKD 712,CKD712

Cat No.	Product Name	Synonyms	Targets
TWA2417	Sodium taurocholate	Taurocholate Sodium	Others
	Sodium taurocholate (Taurocholate Sodium) hydrate is the main end product of cholesterol catabolism. During enterohepatic circulation, bile taurocholic acid is converted by the microorganisms to taurodeoxycholic acid and...		Others
TC0036	Compound Lup-20(29)-en-3-yl acetate		IL Receptor , VEGFR , Others , TNF , COX
	Lupeol acetate, a derivative of Lupeol, inhibits the progression of rheumatoid arthritis by downregulating TNF-α, IL-1β, MCP-1, COX-2, VEGF and granzyme B.		IL Receptor , VEGFR , Others , TNF , COX
T3890	Verbenalin	Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin	Others
	Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.		Others
T7203	Oglufanide	L-Glutamyl-L-tryptophan,H-Glu-Trp-OH	VEGFR , HCV Protease , Endogenous Metabolite
	Oglufanide (H-Glu-Trp-OH) is a naturally occurring thymic immunomodulator,and inhibits vascular endothelial growth factor (VEGF).		VEGFR , HCV Protease , Endogenous Metabolite
T5429	Theaflavin 3,3'-digallate	8-Gingerol,TFDG	Virus Protease , Antioxidant , HIV Protease , HSV
	Theaflavin 3,3'-digallate (8-Gingerol) , a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregul...		Virus Protease , Antioxidant , HIV Protease , HSV
T5740	25(R,S)-Ruscogenin	(25RS)-Ruscogenin	Others , HIF
	25(R,S)-Ruscogenin is a natual product.		Others , HIF
T4S1551	Cinnamaldehyde	Cinnamic Aldehyde	HIF
	1. Cinnamaldehyde (Cinnamic Aldehyde) has antipyretic activity. 2. Cinnamaldehyde is a sedative agent. 3. Cinnamaldehyde inhibits invasive capabilities of MDA-MB-435S cells was correlated with down-regulating the express...		HIF
T3S2344	β,β-Dimethylacrylshikonin	Dimethylacrylshikonin,β, β-Dimethylacrylshikonin	ERK , HIF/HIF Prolyl-Hydroxylase
	1. β,β-Dimethylacrylshikonin (Dimethylacrylshikonin) is a promising agent for developing an improved strategy for radiotherapy against tumors. (a) Injection of Dimethylacrylshikonin combined with IR treatment significant...		ERK , HIF/HIF Prolyl-Hydroxylase
TN3139	5α-Hydroxycostic acid	5alpha-Hydroxycostic acid	ERK , FAK , Phospholipase , NOS , Akt , Src
	5alpha-Hydroxycostic acid possesses anti-angiogenic ability by interfering the VEGF- and Ang2-related pathways, and it may be a good drug candidate.		ERK , FAK , Phospholipase , NOS , Akt , Src
T14055	5Z-7-Oxozeaenol	FR148083,L783279,LL-Z 1640-2	VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
	5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...		VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
TN4356	Jolkinolide A		Akt , STAT , mTOR
	Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly inhibited the proliferation and migration of HUVECs.		Akt , STAT , mTOR
TN5942	Dammarenediol II	Dammar-24-ene-3,20-diol
	Dammarenediol II may have the ability to prevent diabetic microvascular complications, including diabetic retinopathy, it can inhibit vascular endothelial growth factor (VEGF)-induced intracellular reactive oxygen specie...
T75487	7-Hydroxyneolamellarin A
	7-Hydroxyneolamellarin A, a natural product from the sponge Dendrilla nigra, serves as a potent inhibitor of hypoxia-inducible factor-1α (HIF-1α). It effectively reduces the accumulation of HIF-1α protein and suppresses ...
T36749	Herboxidiene
	Herboxidiene is a polyketide originally isolated from S. chromofuscus that has diverse biological activities.[1],[2,][3],[4],[5] It inhibits growth of HeLa S3, SK-MEL-2, PC3, A549, and EBC-1 cells with GI50 values rangin...

Natural Products

Sodium taurocholate

TWA2417

Synonym: Taurocholate Sodium

Target: Others

Compound Lup-20(29)-en-3-yl acetate

TC0036

Synonym:

Target: IL Receptor, VEGFR, Others, TNF, COX

Verbenalin

T3890

Synonym: Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin

Target: Others

Oglufanide

T7203

Synonym: L-Glutamyl-L-tryptophan,H-Glu-Trp-OH

Target: VEGFR, HCV Protease, Endogenous Metabolite

Theaflavin 3,3'-digallate

T5429

Synonym: 8-Gingerol,TFDG

Target: Virus Protease, Antioxidant, HIV Protease, HSV

25(R,S)-Ruscogenin

T5740

Synonym: (25RS)-Ruscogenin

Target: Others, HIF

Cinnamaldehyde

T4S1551

Synonym: Cinnamic Aldehyde

Target: HIF

β,β-Dimethylacrylshikonin

T3S2344

Synonym: Dimethylacrylshikonin,β, β-Dimethylacrylshikonin

Target: ERK, HIF/HIF Prolyl-Hydroxylase

5α-Hydroxycostic acid

TN3139

Synonym: 5alpha-Hydroxycostic acid

Target: ERK, FAK, Phospholipase, NOS, Akt, Src

5Z-7-Oxozeaenol

T14055

Synonym: FR148083,L783279,LL-Z 1640-2

Target: VEGFR, FLT, MEK, MAPK, PDGFR, Antibiotic, Src

Jolkinolide A

TN4356

Synonym:

Target: Akt, STAT, mTOR

Dammarenediol II

TN5942

Synonym: Dammar-24-ene-3,20-diol

Target:

7-Hydroxyneolamellarin A

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00865	VEGF121 Protein, Human, Recombinant (His)	Human	Human Cells
	Human VEGF121, also known as Vascular endothelial growth factor A, VEGFA, Vascular permeability factor, VPF and VEGF, is a homodimeric, heparin-binding glycoprotein which belongs to the platelet-derived growth factor (PD...
TMPY-01717	VEGF164 Protein, Mouse, Recombinant	Mouse	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-03698	VEGF121b Protein, Human, Recombinant	Human	HEK293
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-05798	VEGF145 Protein, Human, Recombinant	Human	HEK293
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-01656	VEGF183 Protein, Human, Recombinant	Human	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-02432	VEGF164 Protein, Rat, Recombinant	Rat	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-03156	VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)	Mouse,Rat	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-01007	VEGFC Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPJ-00864	VEGF165 Protein, Human, Recombinant	Human	Human Cells
	Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator...
TMPY-01321	DLL4 Protein, Human, Recombinant (His)	Human	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-04911	VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated	Human,Cynomolgus	HEK293
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPY-01337	DLL4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-00776	DLL4 Protein, Human, Recombinant (hFc)	Human	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPK-00823	VEGF165 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-01008	VEGFD Protein, Human, Recombinant (His)	Human	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-04803	DLL4 Protein, Human, Recombinant	Human	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPY-01936	VEGFR3/FLT4 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor receptor 3 (VEGFR3), also known as FLT-4, together with the other two members VEGFR1 (FLT-1) and VEGFR2 (KDR/Flk-1) are receptors for vascular endothelial growth factors (VEGF) and belo...
TMPY-02361	VEGFR2/KDR Protein, Human, Recombinant (His)	Human	HEK293
	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restricted to endothelial cells in vivo. VEGFR2 was shown to be ...
TMPJ-00735	PDGF-BB Protein, Human, Recombinant	Human	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPY-03763	Neuropilin-2 Protein, Human, Recombinant (hFc)	Human	HEK293
	Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-00892	Neuropilin-2 Protein, Human, Recombinant (His)	Human	HEK293
	Neuropilin-2 (NRP-2) which is related to NRP-1, is a type I? transmembrane glycoprotein and has the structure characteristic with five main extracellular domains: two complement binding (CUB) domains, two coagulation fac...
TMPY-00637	FLT1 Protein, Human, Recombinant (aa 1-328, His)	Human	HEK293
	Vascular endothelial growth factor receptor 1, also known as VEGFR-1, Fms-like tyrosine kinase 1, Tyrosine-protein kinase FRT, Tyrosine-protein kinase receptor FLT, Vascular permeability factor receptor and FLT1, is a si...
TMPJ-00412	VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)	Human	Human Cells
	Human Vascular endothelial growth factor receptor 1(VEGFR-1, FLT-1) is a member of the the class III subfamily of receptor tyrosine kinases (RTKs) and Tyr protein kinase family and CSF-1/PDGF receptor subfamily. VEGFR-1 ...
TMPJ-00562	PDGF-BB Protein, Mouse, Recombinant (His)	Mouse	E. coli
	Platelet-Derived Growth Factor Subunit B (PDGFB) belongs to the PDGF/VEGF growth factor family. Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. PDGFB can exist either as a homodimer (P...
TMPY-01906	SEMA4D Protein, Human, Recombinant (His)	Human	HEK293
	Semaphorin 4D (SEMA4D or CD100) is a member of the semaphorin family of proteins and an important mediator of the movement and differentiation of multiple cell types, including those of the immune, vascular, and nervous ...
TMPY-02836	MFGE8 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	MFG-E8, also known as lactadherin and MFGE8, contains 1 EGF-like domain and 2 F5/8 type C domains. It also contains phosphatidylserine (PS) binding domain, as well as an Arginine-Glycine-Aspartic acid motif, which enable...
TMPY-04976	PDGFC Protein, Mouse, Recombinant (His)	Mouse	Yeast
	PDGF-C is a member of the PDGF/VEGF family of growth factors with a unique domain organization and expression pattern. Platelet-derived growth factor receptors (PDGFRs) are catalytic receptors that have intracellular tyr...
TMPY-00891	Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)	Human	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-00356	Neuropilin-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-05740	Neuropilin-1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-02367	Neuropilin-1 Protein, Human, Recombinant (isoform b, His)	Human	HEK293
	Neuropilin is a type I transmembrane protein and the molecular mass is 120 kDa. Two homologs, Neuropilin-1 and Neuropilin-2, are identified. The primary structure of Neuropilin-1 and Neuropilin-2 is well conserved and is...
TMPY-01915	DLL1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-01379	DLL1 Protein, Human, Recombinant (His)	Human	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-05833	DLL1 Protein, Human, Recombinant (hFc)	Human	HEK293
	Delta-like protein 1(DLL1), also known as Delta1, a single-pass type I membrane protein which contains one DSL domain and eight EGF-like domains, acts as a ligand for Notch receptors, and positively regulates T-cell deve...
TMPY-03155	VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)	Mouse,Rat	HEK293
	Vascular endothelial growth factor C (VEGF-C) is a member of the VEGF family. Upon biosynthesis, VEGF-C protein is secreted as a non-covalent momodimer in an anti-parellel fashion. VEGF-C protein is a dimeric glycoprotei...
TMPY-03705	VEGF164 Protein, Canine, Recombinant	Canine	HEK293
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPK-00825	VEGF121 Protein, Human, Recombinant (His & Avi)	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPJ-00414	VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated	Human	Human Cells
	Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the re...
TMPJ-00355	Neuropilin-1 Protein, Human, Recombinant (aa 22-644, Avi & His), Biotinylated	Human	Human Cells
	Neuropilin-1 (Npn-1, previously neuropilin; also CD304) is a 130 - 140 kDa type I transmembrane (TM) glycoprotein that regulates axon guidance and angiogenesis. Two homologues, Neuropilin-1 and Neuropilin-2, are identifi...
TMPY-03080	VEGF165 Protein, Danio rerio (zebrafish), Recombinant	Danio rerio (zebrafish)	Baculovirus-Insect Cells
	Vascular endothelial growth factor (VEGF), also known as vascular permeability factor (VPF) and VEGF-A, is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. It is a member of the platelet-...
TMPJ-00593	VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)	Human	Human Cells
	Human Vascular endothelial growth factor receptor 2(KDR, VEGFR-2) is a member of the class III subfamily of receptor tyrosine kinases (RTKs). KDR is involved in a number of fundamental biological processes such as the re...
TMPK-00822	VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-05093	DLL4 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
TMPJ-00987	PLGF/PGF Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Placental growth factor is a protein that in humans is encoded by the PGF gene. It is a secreted protein and belongs to the PDGF/VEGF growth factor family. The protein is a member of the VEGF (vascular endothelial growth...
TMPH-03241	Angiopoietin-2 Protein, Rat, Recombinant (E. coli, His)	Rat	E. coli
	Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, AN...
TMPH-03240	Angiopoietin-2 Protein, Rat, Recombinant (His)	Rat	Baculovirus
	Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, AN...
TMPK-00826	VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most a...
TMPY-03150	VEGFD Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Vascular endothelial growth factor D (VEGF-D), also known as C-fos induced growth factor (FIGF), belongs to the platelet-derived growth factor/vascular endothelial growth factor (PDGF/VEGF) family. FIGF protein is active...
TMPY-02945	Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	EG-VEGF, also known as prokineticin-1, is a member of the AVIT (prokineticin) family. Prokineticins are secreted proteins that can promote angiogenesis and induce strong gastrointestinal smooth muscle contraction. EG-VEG...
TMPY-06876	DLL4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
	Delta-like protein 4 (DLL4, Delta4), a type I membrane-bound Notch ligand, is one of five known Notch ligands in mammals and interacts predominantly with Notch 1, which has a key role in vascular development. Recent stud...
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VEGF121 Protein, Human, Recombinant (His)

TMPJ-00865

Species: Human

Expression System: Human Cells

VEGF164 Protein, Mouse, Recombinant

TMPY-01717

Species: Mouse

Expression System: Baculovirus-Insect Cells

VEGF121b Protein, Human, Recombinant

TMPY-03698

Species: Human

Expression System: HEK293

VEGF145 Protein, Human, Recombinant

TMPY-05798

Species: Human

Expression System: HEK293

VEGF183 Protein, Human, Recombinant

TMPY-01656

Species: Human

Expression System: Baculovirus-Insect Cells

VEGF164 Protein, Rat, Recombinant

TMPY-02432

Species: Rat

Expression System: Baculovirus-Insect Cells

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, His)

TMPY-03156

Species: Mouse,Rat

Expression System: HEK293

VEGFC Protein, Human, Recombinant (His)

TMPY-01007

Species: Human

Expression System: HEK293

VEGF165 Protein, Human, Recombinant

TMPJ-00864

Species: Human

Expression System: Human Cells

DLL4 Protein, Human, Recombinant (His)

TMPY-01321

Species: Human

Expression System: HEK293

VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-04911

Species: Human,Cynomolgus

Expression System: HEK293

DLL4 Protein, Mouse, Recombinant (His)

TMPY-01337

Species: Mouse

Expression System: HEK293

DLL4 Protein, Human, Recombinant (hFc)

TMPY-00776

Species: Human

Expression System: HEK293

VEGF165 Protein, Human, Recombinant (His & Avi)

TMPK-00823

Species: Human

Expression System: HEK293

VEGFD Protein, Human, Recombinant (His)

TMPY-01008

Species: Human

Expression System: HEK293

DLL4 Protein, Human, Recombinant

TMPY-04803

Species: Human

Expression System: HEK293

VEGFR3/FLT4 Protein, Mouse, Recombinant (His)

TMPY-01936

Species: Mouse

Expression System: HEK293

VEGFR2/KDR Protein, Human, Recombinant (His)

TMPY-02361

Species: Human

Expression System: HEK293

PDGF-BB Protein, Human, Recombinant

TMPJ-00735

Species: Human

Expression System: E. coli

Neuropilin-2 Protein, Human, Recombinant (hFc)

TMPY-03763

Species: Human

Expression System: HEK293

Neuropilin-2 Protein, Human, Recombinant (His)

TMPY-00892

Species: Human

Expression System: HEK293

FLT1 Protein, Human, Recombinant (aa 1-328, His)

TMPY-00637

Species: Human

Expression System: HEK293

VEGFR1/FLT-1 Protein, Human, Recombinant (hFc)

TMPJ-00412

Species: Human

Expression System: Human Cells

PDGF-BB Protein, Mouse, Recombinant (His)

TMPJ-00562

Species: Mouse

Expression System: E. coli

SEMA4D Protein, Human, Recombinant (His)

TMPY-01906

Species: Human

Expression System: HEK293

MFGE8 Protein, Human, Recombinant (His)

TMPY-02836

Species: Human

Expression System: Baculovirus-Insect Cells

PDGFC Protein, Mouse, Recombinant (His)

TMPY-04976

Species: Mouse

Expression System: Yeast

Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

TMPY-00891

Species: Human

Expression System: HEK293

Neuropilin-1 Protein, Cynomolgus, Recombinant (His)

TMPY-00356

Species: Cynomolgus

Expression System: HEK293

Neuropilin-1 Protein, Mouse, Recombinant (His)

TMPY-05740

Species: Mouse

Expression System: HEK293

Neuropilin-1 Protein, Human, Recombinant (isoform b, His)

TMPY-02367

Species: Human

Expression System: HEK293

DLL1 Protein, Mouse, Recombinant (His)

TMPY-01915

Species: Mouse

Expression System: HEK293

DLL1 Protein, Human, Recombinant (His)

TMPY-01379

Species: Human

Expression System: HEK293

DLL1 Protein, Human, Recombinant (hFc)

TMPY-05833

Species: Human

Expression System: HEK293

VEGFC Protein, Mouse/Rat, Recombinant (aa 108-223, hFc)

TMPY-03155

Species: Mouse,Rat

Expression System: HEK293

VEGF164 Protein, Canine, Recombinant

TMPY-03705

Species: Canine

Expression System: HEK293

VEGF121 Protein, Human, Recombinant (His & Avi)

TMPK-00825

Species: Human

Expression System: HEK293

VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His & Avi), Biotinylated

TMPJ-00414

Species: Human

Expression System: Human Cells

Neuropilin-1 Protein, Human, Recombinant (aa 22-644, Avi & His), Biotinylated

TMPJ-00355

Species: Human

Expression System: Human Cells

VEGF165 Protein, Danio rerio (zebrafish), Recombinant

TMPY-03080

Species: Danio rerio (zebrafish)

Expression System: Baculovirus-Insect Cells

VEGFR2/KDR Protein, Human, Recombinant (aa 20-764, His)

TMPJ-00593

Species: Human

Expression System: Human Cells

VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled

TMPK-00822

Species: Human

Expression System: HEK293

DLL4 Protein, Rhesus, Recombinant (His)

TMPY-05093

Species: Rhesus

Expression System: HEK293

PLGF/PGF Protein, Mouse, Recombinant (His)

TMPJ-00987

Species: Mouse

Expression System: Human Cells

Angiopoietin-2 Protein, Rat, Recombinant (E. coli, His)

TMPH-03241

Species: Rat

Expression System: E. coli

Angiopoietin-2 Protein, Rat, Recombinant (His)

TMPH-03240

Species: Rat

Expression System: Baculovirus

VEGF121 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00826

Species: Human

Expression System: HEK293

VEGFD Protein, Mouse, Recombinant (His)

TMPY-03150

Species: Mouse

Expression System: HEK293

Prokineticin 1/EG-VEGF Protein, Human, Recombinant (His)

TMPY-02945

Species: Human

Expression System: Baculovirus-Insect Cells

DLL4 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPY-06876

Species: Human

Expression System: HEK293

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Cat No.	Product Name
L2192	Anti-Pancreatic Cancer Compound Library	2238 compounds
	A unique collection of 2238 pancreatic cancer related compounds can be used in HTS and HCS;
L4800	Angiogenesis related Compound Library	1353 compounds
	A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
L2191	Anti-Breast Cancer Compound Library	1939 compounds
	A unique collection of 1939 compounds with anti-breast cancer therapeutic activity or targeting breast cancer’s major signaling pathways, can be used for anti-breast cancer drug discovery and mechanism study；

Libraries

Anti-Pancreatic Cancer Compound Library

L2192

Compounds: 2238

Angiogenesis related Compound Library

L4800

Compounds: 1353

Anti-Breast Cancer Compound Library

L2191

Compounds: 1939