Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 34.00 | |
2 mg | In stock | $ 47.00 | |
5 mg | In stock | $ 72.00 | |
10 mg | In stock | $ 122.00 | |
25 mg | In stock | $ 233.00 | |
50 mg | In stock | $ 346.00 | |
100 mg | In stock | $ 513.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 79.00 |
Description | Su1498 (Tyrphostin SU 1498) is a selective inhibitor of the receptor tyrosine kinase VEGF receptor 2 (VEGFR2, aka FLK1; IC50 = 700 nM), having negligible activity at several other serine/threonine and tyrosine kinases.1, 2 It effectively blocks signaling through VEGFR2 both in vitro and in vivo.1, 3 SU 1498 is used to study the role of VEGFR2 signaling in diverse processes, including angiogenesis, tumor growth, neural progenitor cell survival, and neuroregeneration. |
Targets&IC50 | VEGFR2:700 nM |
Synonyms | Tyrphostin SU 1498, AG 1498 |
Molecular Weight | 390.52 |
Formula | C25H30N2O2 |
CAS No. | 168835-82-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 150 mg/mL (384.10 mM)
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Su1498 168835-82-3 Angiogenesis Tyrosine Kinase/Adaptors VEGFR Vascular endothelial growth factor receptor Inhibitor Su-1498 Tyrphostin SU 1498 inhibit AG1498 AG-1498 Tyrphostin SU-1498 Tyrphostin SU1498 SU 1498 AG 1498 inhibitor