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TargetMol | Compound Library

Angiogenesis related Compound Library

Catalog No. L4800

Angiogenesis is a normal and vital process in growth and development, as well as in wound healing and in the formation of granulation tissue. However, uncontrolled angiogenesis underlies many deadly and debilitating conditions, including cancer, skin diseases, immune disorders, diabetic ulcers, cardiovascular disease, stroke, critical limb ischemia, and many others. Therefore, angiogenesis has become an attractive target for combating diseases characterized by either poor vascularization or abnormal vasculature. For example, angiogenesis plays a critical role in the growth of cancer. Tumors induce blood vessel growth (angiogenesis) by secreting various growth factors (e.g. VEGF) and proteins which induce capillary growth into the tumor, providing it with oxygen and nutrients. Angiogenesis is also required for the spread of a tumor, or metastasis. Therefore, angiogenesis inhibitors can be used to treat cancer. In addition, proangiogenic therapies are being explored as options to treat ischemic cardiovascular diseases by formation of “natural bypasses”—that is, collateral vessels. The TargetMol’s Angiogenesis related Compound Library, a unique collection of angiogenesis related compounds, can be used for research in angiogenesis and related drug discovery.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

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Catalog No. L4800

Angiogenesis related Compound Library
sizeIn stock
  • 1 mg
  • 30 μL x 10 mM (in DMSO)
  • 50 μL x 10 mM (in DMSO)
  • 100 μL x 10 mM (in DMSO)
  • 250 μL x 10 mM (in DMSO)
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Product Description Product Description

  • A unique collection of 1353 proangiogenic and antiangiogenic compounds for new targets identification, research in mechanisms of angiogenesis, and high throughput screening (HTS) and high content screening (HCS);
  • Targets include angiogenesis signaling, and related targets such as S1P, VEGFR, PDGF, etc.;
  • Includes approved drugs targeting angiogenesis, such as Sunitinib Malate, Lenalidomide, sorafenib, Erlotinib; drugs in clinical development with the most potential targeting angiogenesis, such as Vatalanib, Orantinib, 2-Methoxyestradiol (Panzem), Celecoxib;
  • Detailed compound information with structure, target, activity, IC50 value, and biological activity description;
  • Structurally diverse, medicinally active, and cell permeable;
  • NMR and HPLC validated to ensure high purity and quality;

Packaging And Storage | TargetMol Packaging And Storage

  • Powder or pre-dissolved DMSO solutions in 96/384 well plate with optional 2D barcode
  • Shipped with blue ice

Library Customization | TargetMol Library Customization

Compound Library | TargetMol
Targetmol Compound Libraries
can be highly customized!
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Library Customization | TargetMol Library Composition

5-HT Receptor
Apoptosis
Autophagy
PI3K
EGFR
VEGFR
JAK
Src
FLT
PDGFR
Dopamine Receptor
Akt
FGFR
TNF
COX
c-Kit
MMP
Bcr-Abl
RAAS
ALK
mTOR
Adrenergic Receptor
TGF-beta/Smad
NF-κB
BTK
Endogenous Metabolite
HER
Histamine Receptor
Tyrosine Kinases
c-Met/HGFR
Antibacterial
HIF
IL Receptor
FAK
DNA-PK
AChR
ERK
CDK
HIF/HIF Prolyl-Hydroxylase
Serotonin Transporter
Reactive Oxygen Species
c-RET
STAT
Syk
p38 MAPK
Aurora Kinase
IGF-1R
PKC
Norepinephrine
Raf
Potassium Channel
Parasite
c-Fms
TAM Receptor
PKA
Influenza Virus
Trk receptor
AMPK
JNK
NO Synthase
HDAC
HIV Protease
ROS
MEK
S6 Kinase
Virus Protease
Caspase
Mitophagy
CSF-1R
Drug Metabolite
Interleukin
P450
Antibiotic
Tyrosinase
Lipoxygenase
Casein Kinase
ROS Kinase
GSK-3
Integrin
Ferroptosis
Antifungal
PDE
DNA/RNA Synthesis
Prostaglandin Receptor
Ephrin Receptor
ATM/ATR
PI4K
MLK
Sodium Channel
HCV Protease
Antioxidant
PYK2
ROCK
PPAR
Chk
P-gp
TLR
SARS-CoV
PDK
Nrf2
Ligand for E3 Ligase
Microtubule Associated
NOS
Carbonic Anhydrase
Histone Methyltransferase
Tie-2
Transferase
Dehydrogenase
Adenosine Receptor
IFNAR
Serine/threonin kinase
Topoisomerase
Opioid Receptor
BCL
HSV
ACK
MAPK
IκB/IKK
PLK
Sigma receptor
Estrogen/progestogen Receptor
DYRK
Ligands for Target Protein for PROTAC
PARP
Serine Protease
TRP/TRPV Channel
MRP
Hck
Glucosidase
CaMK
PGE Synthase
HSP
Sirtuin
Molecular Glues
CCR
AChE
Survivin
Beta Amyloid
Reverse Transcriptase
Discoidin Domain Receptor (DDR)
Anti-infection
NOD
BACE
Proton pump
VDA
Wnt/beta-catenin
Calcium Channel
MAO
iGluR
IRE1
RIP kinase
Leukotriene Receptor
Guanylate cyclase
GluR
Epigenetic Reader Domain
BCRP
transporter
PTEN
ribosome
SGK
IRAK
GABA Receptor
NOD-like Receptor (NLR)
p53
Chloride channel
PROTACs
ROR
DNA Alkylator/Crosslinker
NADPH
Phosphatase
Melatonin Receptor
Melanin-concentrating Hormone Receptor (MCHR)
ATPase
YAP
LTR
Na+/Ca2+ Exchanger
PERK
Estrogen Receptor/ERR
Amylase
Myosin
LDL
HBV
Pim
cell cycle arrest
FXR
Immunology/Inflammation related
E1/E2/E3 Enzyme
Gamma-secretase
GRK
P2X Receptor
Antifection
Monoamine Transporter
DNA Alkylation
Stearoyl-CoA Desaturase (SCD)
CXCR
DUB
ATP Citrate Lyase
Beta-Secretase
Acyltransferase
STING
LRRK2
Free radical scavengers
PROTAC Linker
Hedgehog/Smoothened
FAAH
Endothelin Receptor
PAD
Epoxide Hydrolase
SGLT
MNK
Histone Acetyltransferase
Pyroptosis
Neprilysin
GST
p97
CFTR
PKM
RSV
Hippo pathway
CRISPR/Cas9
Phospholipase
Gap Junction Protein
NADPH-oxidase
S1P Receptor

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