keep away from direct sunlight,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
HIF-1α-IN-2 is a novel and highly potent HIF-1α inhibitor with anticancer and antitumor activity that inhibits the expression of HIF-1α and VEGF in a dose-dependent manner and inhibits cell migration.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
2 mg | In stock | $ 82.00 | |
5 mg | In stock | $ 147.00 |
Description | HIF-1α-IN-2 is a novel and highly potent HIF-1α inhibitor with anticancer and antitumor activity that inhibits the expression of HIF-1α and VEGF in a dose-dependent manner and inhibits cell migration. |
Targets&IC50 | HIF1α (MiaPaCa-2):15 nM, HIF1α (MDA-MB-231):28 nM |
In vitro | HIF-1α-IN-2 (0-1 μM; 72h) dose-dependently inhibits the expression of HIF-1α and VEGF and suppresses HIF-1α mRNA levels in MDA-MB-231 cells under hypoxic conditions[1]. |
Molecular Weight | 361.46 |
Formula | C21H19N3OS |
CAS No. | 2762315-06-8 |
keep away from direct sunlight,keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mg/mL (27.67 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
bottom
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
HIF-1α-IN-2 2762315-06-8 Angiogenesis Chromatin/Epigenetic HIF inhibitor inhibit