5α-Hydroxycostic acid

Name: 5α-Hydroxycostic acid
Brand: TargetMol
SKU: TN3139
Price: 99 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN3139Cas No. 132185-83-2

Alias 5 alpha-Hydroxycostic acid

5α-Hydroxycostic acid, a naturally occurring sesquiterpene, inhibits choroidal neovascularization in rats through dual signaling pathways mediated by VEGF/VEGFR and Ang2/Tie2 (angiopoietin 2), and exhibits anti-inflammatory and anti-angiogenic effects on human breast cancer cells

5α-Hydroxycostic acid

🥰Excellent

Catalog No. TN3139Alias 5 alpha-Hydroxycostic acidCas No. 132185-83-2

Pack Size	Price	Availability	Quantity
1 mg	$99	In Stock

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Description	5α-Hydroxycostic acid, a naturally occurring sesquiterpene, inhibits choroidal neovascularization in rats through dual signaling pathways mediated by VEGF/VEGFR and Ang2/Tie2 (angiopoietin 2), and exhibits anti-inflammatory and anti-angiogenic effects on human breast cancer cells
In vitro	Methods: RCSEC cells were treated with 5α-Hydroxycostic acid (25, 50, 100 μM, 48 hours) and the inducing factor VEGF164 (30 μM) was added. Cell viability was measured by CCK8. Results: The drug had a significant effect on cell viability at concentrations above 100 μM. [1]
Synonyms	5 alpha-Hydroxycostic acid

Chemical Properties

Molecular Weight	250.33
Formula	C₁₅H₂₂O₃
Cas No.	132185-83-2
Smiles	O[C@]12[C@@](C)(CC[C@@H](C(C(O)=O)=C)C1)CCCC2=C
Relative Density.	1.12 g/cm3 (Predicted)

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keep away from direct sunlight | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

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