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Cat No. | Product Name | Synonyms | Targets |
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T21629 | Loxapine | Dopamine Receptor , 5-HT Receptor | |
Loxapine is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent,used primarily in the treatment of schizophrenia. The drug is a member of the dibenzoxazepine class ... | |||
T3133 | YM-90709 | YM90709,YM 90709 | IL Receptor , Interleukin |
YM-90709 is a new-type antagonist inhibiting the binding of interleukin-5 to the interleukin-5 receptor. | |||
T1412 | Loxapine succinate | Daxolin,Loxapac,Cloxazepin,Loxapine succinate salt | Dopamine Receptor , 5-HT Receptor |
Loxapine succinate (Loxapac), a D2DR and D4DR inhibitor, is utilized in schizophrenia. | |||
T9962 | Mepolizumab | SB 240563 | IL Receptor |
Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis. | |||
T72598 | IL-17 modulator 5 | ||
IL-17 modulator 5 is a IL-17 inhibitor, with an IC 50 of 1 nM . | |||
T0117 | Suplatast (Tosilate) | IPD 1151T,Suplatast tosilate,Suplatast Tosylate | IL Receptor , Interleukin |
Suplatast Tosilate (IPD 1151T) is a novel capsular anti-asthmatic drug. It ( IC50 above 100 μM) inhibits both IgE production, IL-4 and IL-5 synthesis. | |||
T9840 | Ataquimas | Immunology/Inflammation related | |
Ataquimast inhibits IL-5 secretion along with that of TNF-a, IL-4 and GM-CSF from human cells. | |||
T27026 | CJ-13,610 | CJ 13610,CJ-13610 | Lipoxygenase |
CJ-13,610 is an orally active and nonredox-type inhibitor of 5-lipoxygenase (5-LOX). CJ-13,610 inhibits the biosynthesis of leukotriene B4 and regulates the expression of IL-6 mRNA in macrophages. | |||
TP2008L | Lyn peptide inhibitor acetate | Lyn peptide inhibitor acetate(222018-18-0 free base) | IL Receptor |
Lyn peptide inhibitor acetate is a potent and cell-permeable inhibitor of Lyn-coupled IL-5 receptor signaling pathway, while keeping other signals intact. Lyn peptide inhibitor blocks Lyn activation and inhibits the bind... | |||
T7606 | Guanosine 5'-diphosphate disodium salt | 5'-GDP-Na2 | Endogenous Metabolite |
Guanosine 5'-diphosphate disodium salt (5'-GDP-Na2) is a nucleoside diphosphate, is a potential iron mobilizer, which prevents the hepcidin-ferroportin interaction and modulating the interleukin-6 (IL-6)/stat-3 pathway. | |||
T2061 | APY0201 | PI3K , Interleukin | |
APY0201 is a effective, highly specific, ATP-competitive PIKfyve inhibitor (IC50: 5.2 nM). It can interrupt the conversion of phosphatidylinositol 3-phosphate (PtdIns3P) to PtdIns(3, 5)P2. | |||
T3537 | GSK583 | RIP kinase | |
GSK583 is a highly effective and specific RIP2 kinase inhibitor (IC50: 5 nM). | |||
T10497 | Benralizumab | BIW-8405,MEDI-563 | Apoptosis , IL Receptor , Interleukin |
Benralizumab (MEDI-563) is a monoclonal antibody targeting the interleukin-5 receptor alpha (IL-5Rα). It enhances antibody-dependent cell-mediated cytotoxicity, leading to a rapid depletion of eosinophils. Benralizumab i... | |||
T77675 | TNKS-2-IN-1 | PARP , Wnt/beta-catenin , Antibiotic | |
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the releas... | |||
T6838 | FLLL32 | Apoptosis , JAK , STAT | |
FLLL32 is an effective JAK2/STAT3 inhibitor (IC50 of <5 μM). | |||
T38361 | GSK717 | IL Receptor , NOD | |
GSK717 is a potent, selective NOD2 (nucleotide-binding oligomerization domain 2) inhibitor. GSK717 inhibits muramyl dipeptide (MDP)-induced NOD2-mediated signaling, with an IC50 of 400 nM for MDP-stimulated IL-8 secretio... | |||
T5416 | T-5224 | MMP | |
T-5224 is a transcription factor c-Fos/AP-1 inhibitor, which specifically inhibits the DNA binding activity of c-Fos/c-Jun without affecting other transcription factors. | |||
T4615 | Balsalazide sodium hydrate | Balsalazide disodium dihydrate,Balsalazide disodium salt dihydrate,Balsalazide disodium | STAT , Interleukin |
Balsalazide sodium hydrate (Balsalazide disodium) is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.Balsalazide sodium hydrate is a new 5-aminosalicylic acid (5-ASA) containing prodrug.... | |||
T38294 | 4-Deoxypyridoxine hydrochloride | S1P Receptor | |
4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. It inhibits transport of pyridoxine , pyridoxal, and pyridoxamine in and reduces growth of S. carlsbergensis cells. 4-DPD inhib... | |||
T12706 | Reslizumab | Sch 55700 | IL Receptor |
Reslizumab is humanized monoclonal antibodies that target interleukin-5 (IL-5) for the treatment of eosinophilic asthma. | |||
T28243 | Ono 6240 | Ono-6240,Ono6240 | |
Ono 6240 is an antagonist of platelet-activating factor. Ono 6240 prevents airway eosinophilia by inhibiting production of IL-2 and IL-5. | |||
TP2008 | Lyn peptide inhibitor | ||
Cell-permeable inhibitor of Lyn-dependent effects of the IL-5 receptor. Blocks binding of Lyn tyrosine kinase to βc subunit of IL-3/GM-CSF/IL-5 receptors, blocking Lyn activation. Inhibits IL-5 receptor-mediated eosinoph... | |||
T80577 | Varokibart | ||
Varokibart (TEV-53275) is a human IgG4λ antibody that targets interleukin-5 (IL-5) [1]. | |||
T28433 | PNU-142731A HCl | PNU142731A,PNU 142731A,PNU-142731A | |
PNU-142731A HCl, a mediator release inhibitor and an IL-5 production inhibitor, is used potentially for the treatment of asthma. | |||
T70107 | Olcorolimus | ||
Olcorolimus inhibits single allergen-induced allergic inflammation such as eosinophilic and lymphocytic infiltration and mRNA expression for interleukin (IL)-4 and IL-5 | |||
T68474 | RWJ-58643 HCl | ||
RWJ 58643 is a reversible beta-tryptase and trypsin inhibitor. Low-dose RWJ-58643 (100 microg) and budesonide (200 microg) significantly reduced symptoms, eosinophils and levels of IL-5 following NAC. However, higher dos... | |||
T75806 | Lyn peptide inhibitor TFA | ||
Lyn Peptide Inhibitor TFA is a powerful, cell-permeable inhibitor specifically targeting the Lyn-coupled IL-5 receptor signaling pathway, without affecting alternative signaling pathways. It effectively prevents Lyn acti... | |||
T79024 | Androgen receptor-IN-5 | Androgen Receptor | |
Androgen receptor-IN-5 is a potent inhibitor of the androgen receptor with anticancer properties. It additionally suppresses the synthesis of IL-17A, IL-17F, and INF-γ. | |||
T10210 | A-9758 | ROR | |
A-9758 is a RORγ ligand and a selective RORγt inverse agonist (IC50: 5 nM) and exhibits robust potency against IL-17A release. It is effective in suppressing both Th17 differentiation and Th17 effector function. A-9758 s... | |||
T61621 | IMMH001 | ||
IMMH001, also known as SYL930, is an orally active compound that exhibits potent selectivity as an agonist for the S1P1 receptor, which is the sphingosine-1-phosphate receptor 1. This compound effectively reduces the lev... | |||
T79385 | PDE1-IN-5 | ||
PDE1-IN-5 (Compound 10c) is a selective PDE1C inhibitor with an IC50 of 15 nM, exhibiting anti-inflammatory properties through the inhibition of iNOS, TNF-α, IL-1α, IL-1β, and IL-6 expression induced by LPS. It has demon... | |||
T62310 | CDK8-IN-5 | ||
CDK8-IN-5 is a potent inhibitor of CDK8, exhibiting an inhibitory concentration (IC 50) of 72 nM. Demonstrating anti-inflammatory properties, it achieves a 43% enhancement rate of IL-10. This compound holds potential for... | |||
T76869 | Lirentelimab | ||
Lirentelimab (AK002), a humanized IgG1 monoclonal antibody, specifically targets sialic acid-binding Ig-like lectin 8 (SIGLEC8). It promotes apoptosis in IL-5-activated eosinophils and suppresses IgE-mediated activation ... | |||
T22172 | YS-121 | ||
YS121 is a dual inhibitor of microsomal prostaglandin E2 synthase-1 ( mPGES-1; IC 50 =3.4 μM) and 5-lipoxygenase ( 5-LOX; IC 50 =6.5 μM). YS121 dose-dependently reduces the production of PGE2 with EC 50 =12 μM in IL-1β-s... | |||
T80959 | Trabikibart | CSL311 | |
Trabikibart (CSL311), a βc-specific, fully human monoclonal antibody, specifically binds to the cytokine-binding epitope of the human βc receptor with picomolar affinity. It potently inhibits the collective impact of IL-... | |||
T72120 | Guanosine 5'-diphosphate sodium | GDP sodium | |
Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel and serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin i... | |||
T78762 | SIKs-IN-1 | ||
SIKs-IN-1 (compound 8h), a pyrimidine-5-carboxamide derivative, functions as an inhibitor of Salt-inducible kinases (SIKs), which play a role in the M1/M2 macrophage polarization linked to inflammation. By inhibiting SIK... | |||
T64232 | Agatolimod | ||
Agatolimod (ODN 2006) is a TLR9 agonist, a class B ODN (oligodeoxynucleotide) and the optimal human CpG sequence (sequence: 5'-tcgtcgttttttgtcgttttgtcgtt-3'). agatolimod stimulates NO2 and IL-6 production in HD11 cells. ... | |||
T83670 | F1 TFA | Tat-IKIP (46-60),Tat-Inhibitor of NF-κB Kinase-interacting Peptide | |
F1, an anti-inflammatory peptide, incorporates the HIV-1 Tat protein transduction domain linked with a 15-amino acid sequence from residues 46-60 of the inhibitor of NF-κB kinase-interacting peptide (IKIP). It effectivel... | |||
T37554 | Oleyl Anilide | ||
AcylCoA:cholesterol acyltransferase (ACAT) is an intracellular cholesteryl ester synthase tied closely to the absorption of dietary cholesterol. Oleyl analide (OA) is a weak inhibitor of acylCoA:cholesterol acyltransfera... | |||
T75092 | STING agonist-24 | ||
STING agonist-24 (CF504), a non-nucleotide small-molecule STING agonist, activates STING, leading to increased phosphorylation of STING, TBK1, and IRF3. It elevates levels of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and CCL-... | |||
T74911 | ODN 24987 | ||
ODN 24987, a Guanine-modified inhibitory oligonucleotides (ODN) designed to target TLR9, efficiently suppresses the release of IL-6 and IFN-α, showcasing its potential utility in research on immune disorders. The sequenc... | |||
T83773 | Prostaglandin E2 Inhibitor 3 | PGE2 Inhibitor 3 | |
Prostaglandin E2 (PGE2) inhibitor 3 is a selective inhibitor targeting microsomal prostaglandin E synthase-1 (mPGES-1; IC50 = 0.2 µM), demonstrating greater selectivity for mPGES-1 over COX-1, COX-2, 5-lipoxygenase (5-LO... | |||
T36408 | Rhein-13C4 | Rhein-13C4 | |
Rhein-13C4 is intended for use as an internal standard for the quantification of rhein by GC- or LC-MS. Rhein is an anti-inflammatory anthraquinone found in rhubarb and is the bioactive derivative of its prodrug diacerei... | |||
T75093 | STING agonist-25 | ||
STING agonist-23 (CF505) is a non-nucleotide, small-molecule compound that stimulates STING, enhancing the phosphorylation of STING, TBK1, and IRF3. It elevates the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and ... | |||
T75096 | STING agonist-28 | ||
STING agonist-23 (CF510) is a non-nucleotide, small-molecule activator of the STING pathway. It initiates the phosphorylation of STING, TBK1, and IRF3, enhancing the production of IFN-β, IL-6, CXCL-10, TNF-α, ISG-15, and... | |||
T30511 | BMS-279700 | ||
BMS-279700 is a potent oral activity inhibitor that is part of a new family of aniline 5-azimidazolaquoxaline analogs and has excellent anti-inflammatory activity in vivo, as well as in vitro activity against p56LCK and ... | |||
T75094 | STING agonist-26 | ||
STING agonist-23 (CF508), a non-nucleotide small-molecule STING agonist, activates STING, thereby enhancing the phosphorylation of STING, TBK1, and IRF3. This activation elevates the production of IFN-β, IL-6, CXCL-10, T... | |||
T63558 | IRAK4-IN-21 | ||
IRAK4-IN-21 is a selective, orally active, potent IRAK4 inhibitor that acts on IRAK4 (IC50: 5 nM) and TAK1 (IC50: 56 nM). IRAK4-IN-21 exhibits potent inhibition of IL-23 production with an IC50 value of 0.17 μM. can be ... | |||
T75091 | STING agonist-23 | ||
STING agonist-23 (CF502) is a non-nucleotide, small-molecule stimulator of the STING pathway. Upon activation, it enhances the phosphorylation of STING, TBK1, and IRF3, leading to elevated levels of IFN-β, IL-6, CXCL-10,... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TCS2170 | 2,5-Dihydroxyacetophenone | Quinacetophenone,2-Acetylhydroquinone,2-5-dihydroxyacetophenone,Acetylhydroquinone,DHAP | ERK , NF-κB , Tyrosinase |
1. 2,5-Dihydroxyacetophenone (Quinacetophenone) possess anti-anxiety, and neuroprotective qualities. 2. 2,5-Dihydroxyacetophenone (Quinacetophenone) reatment can induce a sustained activation of JNK, ERK1/2, and p38 MAPK... | |||
TN1894 | Luteolin-4'-O-glucoside | Luteolin-4'-glucoside,Luteolin-4-o-glucoside | IL Receptor |
Luteolin-4'-O-glucoside (Luteolin-4-o-glucoside) is an inhibitor of IL-5 (IC50 = 3.7 μM) with anti-complementary, antioxidant and anticancer activity. | |||
T7210 | Guanosine 5'-diphosphate | GDP | Endogenous Metabolite |
Guanosine 5'-diphosphate (GDP) as Potential Iron Mobilizer, Preventing the Hepcidin-Ferroportin Interaction and Modulating the Interleukin-6/Stat-3 Pathway. | |||
T6S1538 | Neochlorogenic acid | trans-5-O-Caffeoylquinic acid,Neochlorogenate,5-O-Caffeoylquinic acid | TNF , NF-κB , COX , Antibacterial , Interleukin |
Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) is an antioxidant compound used in the treatment of oxidative stress and related afflictions. | |||
T4S0145 | Corylifol A | Corylinin | hCE , STAT , UGT |
1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia... | |||
T4115 | Auraptene | 7-geranyloxycoumarin | MMP , BACE |
Auraptene is a coumarin derived from citrus plants that bears a geranyloxyl moiety at its C-7. It has anti-inflammatory, anti-carcinogenic, anti-bacterial, neuroprotective, and hepatoprotective activities. It inhibits le... | |||
T2S0843 | Negletein | 7-O-Methylbaicalein,Baicalein-7-methylether | IL Receptor , TNF , NOS , Interleukin |
1. Negletein (7-O-Methylbaicalein) has anti-inflammatory and immunomodulatory activities via inhibition of TNF-α, iNOS and IL-1β. 2. Negletein as a neuroprotectant enhances the action of nerve growth factor and induces n... | |||
T6S1315 | Oroxylin A | 6-Methoxybaicalein,Baicalein 6-methyl ether | Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy |
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03915 | IL-5 Protein, Human, Recombinant | Human | E. coli |
IL-5 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 13.1 kDa and the accession number is P05113. | |||
TMPY-02554 | IL-5 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus Insect Cells |
IL-5 Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 14.5 kDa and the accession number is P04401. | |||
TMPY-05576 | IL-5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IL-5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P05113. | |||
TMPY-05536 | IL-5 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
IL-5 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 39.5 kDa and the accession number is P05113. | |||
TMPK-00021 | IL-5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k... | |||
TMPK-00771 | IL-5 Protein, Mouse, Recombinant (His & Avi) | Mouse | HEK293 Cells |
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k... | |||
TMPK-00772 | IL-5 Protein, Mouse, Recombinant (His & Avi), Biotinylated | Mouse | HEK293 Cells |
IL-5 is an important cytokine for priming and survival of mature eosinophils and for proliferation and maturation of their progenitors. IL-5(Rα) targeting will be increasingly used in diseases where eosinophils are the k... | |||
TMPJ-00020 | IL-5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
IL-5 is expressed in eosinophils, NK cells, TC2 CD8+ T cells, mast cells, CD45+ CD4+ T cells, gamma delta T cells and IL-1 beta activated endothelial cells. IL-5 acts as a growth and differentiation factor for both B cel... | |||
TMPY-01371 | IL-17RA Protein, Human, Recombinant (His) | Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35 kDa and the accession number is Q96F46-1. | |||
TMPJ-00267 | IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His) | Human | HEK293 Cells |
IL-5R alpha/CD125 Protein, Human, Recombinant (aa 21-335, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 45-60 KDa and the accession number is Q01344. | |||
TMPJ-00266 | IL-5R alpha/CD125 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
IL-5R alpha/CD125 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-85 KDa and the accession number is Q01344. | |||
TMPK-00268 | IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5. ... | |||
TMPK-00269 | IL-5R alpha/CD125 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Interleukin‑5 Receptor alpha (IL‑5 R alpha), also known as CD125, is a 60 kDa hematopoietin receptor that plays a dominant role in eosinophil biology.This is the receptor for interleukin-5. The alpha chain binds to IL5. ... | |||
TMPK-00405 | IL-17RA Protein, Human, Recombinant (aa 33-320, hFc & Avi), Biotinylated | Human | HEK293 Cells |
Interleukin 17 (also known as CTLA‑8) is a T cell‑expressed pleotropic cytokine. IL‑17 binds to IL‑17 receptor (IL‑17 R) which shares no homology with any known family of receptors. While the expression of IL‑17 is restr... | |||
TMPY-05070 | IL-5 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | Baculovirus Insect Cells |
IL-5 Protein, Cynomolgus, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 14.6 kDa. | |||
TMPY-02739 | IL-5 Protein, Canine, Recombinant (His) | Canine | Baculovirus Insect Cells |
IL-5 Protein, Canine, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 14.54 kDa and the accession number is Q95J76. | |||
TMPH-03118 | IL-5 Protein, Pig, Recombinant (His) | Sus scrofa (Pig) | P. pastoris (Yeast) |
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. IL-5 Protein, Pig, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 15... | |||
TMPY-05430 | IL-17RA Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 60.2 kDa and the accession number is Q96F46-1. | |||
TMPY-06391 | IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated | Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (aa 1-320, His & Avi),Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 36.71 kDa and the accession number is Q96F46-1. | |||
TMPY-06390 | IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated | Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 61.99 kDa and the accession number is Q96F46-1. | |||
TMPY-05119 | IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated | Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 61.6 kDa and the accession number is Q96F46-1. | |||
TMPY-05120 | IL-17RA Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 Cells |
IL-17RA Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.9 kDa and the accession number is Q96F46-1. | |||
TMPH-03117 | IL-5 Protein, Pig, Recombinant (E. coli, His) | Sus scrofa (Pig) | E. coli |
Factor that induces terminal differentiation of late-developing B-cells to immunoglobulin secreting cells. IL-5 Protein, Pig, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The pre... | |||
TMPJ-00981 | PTX3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Pentraxin-related protein PTX3, also known as Tumor necrosis factor-inducible gene 14 protein (TSG-14), belongs to the pentraxin family. PTX3 plays a role in the regulation of innate resistance to pathogens, inflammatory... | |||
TMPJ-01210 | IL-33 Protein, Mouse, Recombinant | Mouse | E. coli |
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identifi... | |||
TMPY-06981 | IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) | Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPY-05308 | CD45 Protein, Human, Recombinant (aa 1-529, His) | Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 1-529, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.4 kDa and the accession number is P08575-5. | |||
TMPJ-01234 | IL-36 gamma Protein, Mouse, Recombinant | Mouse | E. coli |
Interleukin-36 gamma (IL-36γ) is a member of the interleukin 1 cytokine family that includes three closely related genes, IL-36α, β, and γ, formerly known as IL-1F6, F8, and F9 respectively. IL-36α has been detected in b... | |||
TMPK-00242 | IL-3R alpha/CD123 Protein, Human, Recombinant (aa 19-305, His & Avi), Biotinylated | Human | HEK293 Cells |
Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein which belongs to the type I cytokine receptor family and Type 5 sub... | |||
TMPJ-01283 | UGRP1 Protein, Human, Recombinant | Human | E. coli |
Uteroglobin-Related Protein 1 (UGRP1) belongs to the secretoglobin family which has been suggested to play a role in lung inflammation and allergic diseases. UGRP1 is a 17 kDa secreted homodimeric protein that shows amin... | |||
TMPY-02893 | NT5C3A/NT5C3 Protein, Human, Recombinant | Human | E. coli |
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded prot... | |||
TMPJ-00789 | Flagellin Protein, Salmonella Typhimurium, Recombinant | Salmonella typhimurium | E. coli |
Flagellin is the major structural protein monomer of bacterial flagella. Flagellin through binding to its receptor and activation of antigen presenting cells stimulates the innate and adaptive immune responses. Flagellin... | |||
TMPJ-01361 | Siglec-8 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Siglec-8 is also known as SIGLEC8, SAF2, SIGLEC-8, SIGLEC8L and sialic acid binding Ig like lectin 8, is an approximately 75 kDa transmembrane glycoprotein in the Siglec family of sialic acid-binding immune regulatory mo... | |||
TMPY-02843 | GPX7 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
GPX7 gene contains 3 distinct gt-ag introns. Transcription produces 4 different mRNAs, 3 alternatively spliced variants, and 1 unspliced form. There are 5 validated alternative polyadenylation sites. The mRNAs appear to ... | |||
TMPY-01816 | Pentraxin 3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Pentraxin-related protein PTX3, also known as Tumor necrosis factor alpha-induced protein 5, Tumor necrosis factor-inducible gene 14 protein, TSG-14, PTX3 and TNFAIP5, is a secreted protein that contains one pentaxin dom... | |||
TMPY-05387 | SLAMF7 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPY-05498 | SR-BI/SCARB1 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
SR-BI/SCARB1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.4 kDa and the accession number is Q8WTV0-5. | |||
TMPJ-00854 | ETS1 Protein, Human, Recombinant (His) | Human | E. coli |
ETS1 Protein (ETS1) is a nuclear protein that belongs to the ETS family. Members of this family recognize the core consensus DNA sequence GGAA/T in target genes. Proteins function either as transcriptional activators or ... | |||
TMPY-04318 | GRIK2 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
GRIK2 (Glutamate Ionotropic Receptor Kainate Type Subunit 2, also known as GluR6) is a Protein Coding gene. The GRIK2 (one of the kainate receptors) gene resides in a genetic linkage region (6q21) associated with bipolar... | |||
TMPY-05547 | SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated | Human | HEK293 Cells |
SLAMF7 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9NQ25-5. | |||
TMPK-01363 | SIRP alpha V5 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... | |||
TMPK-01357 | SIRP alpha V5 Protein, Human, Recombinant (His & Avi) | Human | HEK293 Cells |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl... |
Cat No. | Product Name | ||
---|---|---|---|
L8720 | Pyroptosis Compound Library | 1066 compounds | |
1066 types of active small molecules associated with pyroptosis for high-throughput and high-content screening. | |||
L3800 | NF-κB Signaling Compound Library | 729 compounds | |
A unique collection of 729 compounds targeting NF-κB signaling for high throughput screening and high content screening; | |||
L7600 | Chemokine Inhibitor Library | 59 compounds | |
A unique collection of 59 chemokines or chemokine receptors targeted compounds for high throughput and high content screening; |