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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T32568 | LAP | Lithium PTMB phosphinate | |
LAP is a photocrosslinker for hydrogels. | |||
T16866 | SDZ281-977 | SDZ-LAP 977 | Others |
SDZ 281-977 is a derivative of Lavendustin A which is the EGF receptor tyrosine kinase inhibitor. | |||
T83714 | LAP TFA | Lupus Autoantigen Peptide,La Peptide | |
Lupus autoantigen peptide (LAP), a derivative of the autoantigen La found in systemic lupus erythematosus (SLE) patients, spans amino acids 11-28 of La and functions as an antiviral peptide. It primarily blocks the hepat... | |||
T1689 | Enalapril IMpurity B | (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine | Others |
Enalapril IMpurity B ((+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine) is Moexipril intermediate and is the main metabolite of Imidapril. | |||
T1756L | Ilaprazole | IY81149,IY 81149,IY-81149 | Proton pump , TOPK |
Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm... | |||
T16751 | Rilapladib | SB 659032 | Phospholipase |
Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating factor receptor. | |||
T6486 | Enalapril Maleate | MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate | RAAS |
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy. | |||
T1756 | Ilaprazole sodium | IY-81149 sodium | Proton pump , TOPK |
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus... | |||
T14390L | (2R,3S)-Azelaprag | Apelin receptor | |
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(... | |||
T67799 | Goxalapladib | GSK 677116 | Others |
Goxalapladib(GSK 677116) is a small molecule compound that can be used to treat cardiovascular risks associated with atherosclerosis. | |||
T35054 | Vilaprisan | BAY 1002670,BAY10-02670,BAY-1002670,BAY1002670,BAY-10-02670,BAY 10-02670 | Progesterone Receptor |
Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids. | |||
T83648 | Tenilapine | Others | |
Tenilapine is a neuroleptic compound that can be used to study atypical antipsychotics. | |||
T1605 | Enalapril | MK-421 | RAAS , MRP |
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity. | |||
T6340 | Enalaprilat Dihydrate | MK-422,MK-422 Dihydrate | RAAS , Autophagy |
Enalaprilat Dihydrate (MK-422 Dihydrate) (IC50=1.94 nM) is a potent angiotensin-converting enzyme (ACE) inhibitor. | |||
T32253 | Jalapinolic acid | 11-Hydroxy Palmitic Acid,Builic Acid,Jalapinoic Acid,11-Hydroxyhexadecanoic acid | Others |
Jalapinolic acid (Builic Acid) is a hydroxypalmitic acid. | |||
TQ0113 | Iclaprim | AR-100 | Antibacterial , Antibiotic |
Iclaprim (AR-100) is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL). | |||
T9023 | Atuliflapon | AZD5718 | FLAP |
Atuliflapon (AZD5718) is a novel 5-Lipoxygenase Activating Protein(FLAP) inhibitor for Treatment of Coronary Artery Disease. | |||
T77695 | Muvalaplin | LY3473329 | Others |
Muvalaplin (LY3473329) is an orally active lipoprotein (a) Lp(a) reagent that inhibits Lp(a) formation by blocking apo(a)-apo B100 interactions. | |||
T6235 | Lapatinib Ditosylate | Lapatinib (GW-572016) Ditosylate,GW-572016 ditosylate,Tykerb ditosylate | EGFR , Ferroptosis , Autophagy |
Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2). | |||
T22700 | Cyclapolin 9 | PLK | |
Cyclapolin 9 is a selective, potent, and ATP-competitive inhibitor of polo-like kinase 1 (PLK1) with an IC50 of 500 nM, and has not shown activity against other kinases. | |||
T4510 | Polaprezinc | Zinc L-carnosine | Others |
Polaprezinc is an bioavailable chelate comprised of zinc and L-carnosine, known for its gastrointestinal protective properties, as well as its anti-ulcer, antioxidant, and anti-inflammatory effects. | |||
T16732 | Reproxalap | NS-2,ADX-102 | Others |
Reproxalap (NS-2) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. Reproxalap is a reactive aldehyde species sequestering agent for the treatment of the dry eye. | |||
T11487 | Fiboflapon | GSK2190915,AM-803 | FLAP |
Fiboflapon (GSK2190915) is an orally available and effective 5-lipoxygenase-activating protein (FLAP) inhibitor that binds FLAP with a titer of 2.9 nM and inhibition of LTB4 in human blood with an IC50 of 76 nM. | |||
T8844 | Diflapolin | Others , FLAP , Epoxide Hydrolase | |
Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity. | |||
T5329 | Trandolapril | Angiotensin-converting Enzyme (ACE) | |
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat. | |||
T3716 | Rolapitant | SCH619734 | Neurokinin receptor |
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ... | |||
T0078L | Lapatinib ditosylate monohydrate | Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,Tyverb | EGFR , Ferroptosis , Autophagy |
Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib ditosylate monohydrate therapy is associated w... | |||
T69013 | Alaproclate | ||
Alaproclate is a specific 5-hydroxytryptamine uptake inhibitor and antidepressant. | |||
T27798 | Lapisteride | CS891B,CS-891,CS-891B,CS891 | Others |
Lapisteride (CS-891) a steroidal 5α-reductase inhibitor is used to treat benign prostatic hyperplasia (BPH) and androgenetic alopecia and may be effective in preventing or treating AGA . | |||
T3724 | Rolapitant hydrochloride | Rolapitant HCl | Neurokinin receptor |
Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride (Rolapitant HCl) does not interact with CY... | |||
T16087 | Quiflapon | MK-591 | Apoptosis , FLAP |
Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotr... | |||
T3281 | Delapril hydrochloride | indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317 | RAAS |
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme... | |||
T6190 | Telaprevir | VX-950,LY-570310,Incivek,MP-424 | HCV Protease , SARS-CoV |
Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM). | |||
T0078 | Lapatinib | GSK572016,GW572016 | EGFR , Ferroptosis , Autophagy |
Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression. | |||
T19862 | Voxilaprevir | HCV Protease | |
Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease. | |||
T14390 | Azelaprag | AMG 986 | Apelin receptor |
Azelaprag (AMG 986) is an effective small-molecule apelin receptor agonist. Azelaprag can be used to treat neurological diseases and cardiovascular diseases. | |||
T3015 | Olaparib | AZD2281,KU0059436 | Mitophagy , PARP , Autophagy |
Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 μM), and is selective and orally active. Olaparib exhibits autophagy and m... | |||
T30798 | Cerlapirdine | PF05212365,P -05212365,SAM-531,SAM531,PF-05212365,SAM 531,WAY-262,531 | 5-HT Receptor |
Cerlapirdine (PF-05212365) is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzhei... | |||
T68090 | Laprafylline | Others | |
Laprafylline is a xanthine compound with inhibitory effects on bronchoconstriction in vivo and antitumor activity.Laprafylline acts as a competitive serotonergic antagonist at low concentrations, and inhibits constrictio... | |||
T83647 | (Z)-Tenilapine | Others | |
(Z)-Tenilapine is trans-Tenilapine, cis-Tenilapine has sedative activity. | |||
T26085 | Rilapine | Rilapinum | |
Rilapine is an atypical antipsychotic with high affinity for the 5-HT6 receptor. | |||
T20758 | Trandolaprilat | RU44403,RU-44403,Trandolaprilate,Trandolaprilatum,RU 44403 | |
Trandolaprilat is an inhibitor of non-sulfhydryl angiotensin-converting enzyme. | |||
T6340L | Enalaprilat | MK422,MK 422,MK 421 diacid,Enalapril acid,MK-422 | |
Enalaprilat, the active metabolite of Enalapril, is a effective intravenously administered angiotensin-converting enzyme inhibitor. It is an effective agent for the treatment of essential hypertension and has beneficial ... | |||
T30189 | Atalaphillinine | ||
Atalaphillinine is an acridone alkaloid. | |||
T25628 | Lapyrium | Lapyrium cation | |
Lapyrium is a cationic surfactant that is used in personal care products as a biocide and antistatic. It is also used by the chloride salt, lapyrium chloride, in waste-water treatment and corrosion inhibition formulation... | |||
T78218 | Ilaprazole sodium hydrate | IY-81149 sodium hydrate | Proton pump |
Ilaprazole (IY-81149) sodium hydrate is an orally active proton pump inhibitor that irreversibly inhibits H+/K+-ATPase in rabbit parietal cells with a dose-dependent IC50 of 6 μM. It is employed in gastric ulcer research... | |||
T68330 | Cerlapirdine hydrochloride | ||
Cerlapirdine, also known as SAM-531, WAY-262,531 and PF-05212365, is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine has been in clinical development for the treatment of... | |||
T16274 | Narlaprevir | SCH 900518 | Others |
Narlaprevir is an effective, selective, and orally bioavailable NS3 protease inhibitor(Ki=6 nM; EC90=40 nM). | |||
T70255 | Elapegademase | ||
Elapegademase is an Adenosine Deaminase Inhibitor | |||
T80532 | Ac-AAVALLPAVLLALLAP-YVAD-CHO | Caspase | |
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1]. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T5690 | 7,4'-Di-O-methylapigenin | 4',7-DIMETHOXY-5-HYDROXYFLAVONE | Amylase |
7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines. | |||
T6560 | Lappaconitine hydrobromide | Lappaconite HBr,Allapinine | Others |
Lappaconitine hydrobromide (Allapinine) is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects. | |||
TN1569 | Deoxylapachol | Antifection , Antifungal | |
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevi... | |||
T32570 | Lappaconine | 20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine | Others |
Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) derivated from norditerpenoid alkaloids. | |||
TN7058 | Dihydrolapachenole | 6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene | Others |
Dihydrolapachenole (6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene) can be isolated from T. chrysantha. | |||
T6407 | β-Lapachone | Beta-Lapachone,NSC-26326,SL-11001,ARQ-501 | IDO , Apoptosis , Topoisomerase , Autophagy |
β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase. | |||
TN1375 | α-Lapachone | alpha-Lapachone | Topoisomerase , Antifection |
α-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi. | |||
T4136 | Lapachol | Bethabarra wood,CI75490,Greenhartin,Tecomin | Others , Influenza Virus , Antibacterial , Parasite , Antifungal |
Lapachol (CI75490) has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila melanogaster heterozygote. | |||
T2806 | Lappaconitine | (+)-Lappaconitine | P2X Receptor , Sodium Channel |
Lappaconitine ((+)-Lappaconitine), isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic. | |||
TN3212 | 7,4-Di-O-methylapigenin 5-O-glucoside | Others | |
7,4-Di-O-methylapigenin 5-O-glucoside is a natural product for research related to life sciences. The catalog number is TN3212 and the CAS number is 197018-71-6. | |||
TN6461 | Isolappaol A | ||
Isolappaol A is a natural product for research related to life sciences. The catalog number is TN6461 and the CAS number is 131400-96-9. | |||
TN3620 | Celaphanol A | NF-κB | |
Celaphanol A shows moderate inhibition in both NF-κB activation and nitric oxide production, suggests that it is a possible inhibitor of the NF-kappaB pathway and has antiinflammatory activity. | |||
TN5875 | 6′′-O-β-D-Apiofuranosylapterin | ||
6′′-O-β-D-Apiofuranosylapterin is a natural product for research related to life sciences. The catalog number is TN5875 and the CAS number is 2188162-94-7. | |||
TN6463 | Lappaol B | ||
Lappaol B is a natural product for research related to life sciences. The catalog number is TN6463 and the CAS number is 62359-60-8. | |||
TN2987 | 3Alaph-Tigloyloxypterokaurene L3 | Others | |
3Alaph-Tigloyloxypterokaurene L3 is a natural product from Wedelia trilobata. | |||
TN4410 | Lappaol C | P-gp , JNK | |
Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidat... | |||
TN3213 | 7,4'-Di-O-methylapigenin 5-O-xylosylglucoside | Others | |
7,4'-Di-methylapigenin-5-O-xylosylglucoside shows inhibitory activity for nitric oxide(NO) production by activated RAW 264.7 cells. | |||
TN6199 | Atalaphylline | ||
Atalaphylline is a natural product for research related to life sciences. The catalog number is TN6199 and the CAS number is 28233-35-4. | |||
TN3318 | 9-Hydroxy-alpha-lapachone | Antifection | |
9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. It may have anti-inflammator... | |||
T65249 | Hydroxylapatite | ||
Hydroxylapatite is a natural product for research related to life sciences and the catalog number is T65249. | |||
TN6462 | Isolappaol C | ||
Isolappaol C is a natural product for research related to life sciences. The catalog number is TN6462 and the CAS number is 929905-15-7. | |||
TN3321 | 9-Methoxy-alpha-lapachone | Others | |
9-Methoxy-alpha-lapachone has antitumor-promoting effect, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein- Barr virus early antigen (EBV-EA) activation in Ra... | |||
TN3019 | 4,9-Dihydroxy-alpha-lapachone | Others | |
4,9-Dihydroxy-alpha-lapachone has antitumor-promoting effects, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation i... | |||
TN6152 | N-Methylatalaphylline | ||
N-Methylatalaphylline is a natural product for research related to life sciences. The catalog number is TN6152 and the CAS number is 28233-34-3. | |||
TN4411 | Lappaol F | CDK , P-gp , JNK | |
1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. <br/> 2. Lappaol F has potential chemosensitizing activity, it may be c... | |||
TN3264 | 8,3'-Diprenylapigenin | Others | |
8,3'-Diprenylapigenin is a natural product for research related to life sciences. The catalog number is TN3264 and the CAS number is 955135-37-2. | |||
TN1072 | Lappaol A | P-gp , JNK | |
Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also has potential chemosensitizing activity, it may be candidat... | |||
T83284 | 5-O-Primeverosylapigenin | ||
5-O-Primeverosylapigenin, a member of the primeverosylapigenin class, can be isolated from species within the Gentianaceae family [1]. | |||
T6S1315 | Oroxylin A | 6-Methoxybaicalein,Baicalein 6-methyl ether | Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy |
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPJ-00250 | LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ... | |||
TMPJ-00254 | TGF beta 3 Protein, Human/Mouse/Rat, Recombinant | Human,Mouse,Rat | Human Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti... | |||
TMPY-01133 | Latent TGF beta 1 Protein, Human, Recombinant (His) | Human | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPJ-00249 | TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated | Human | Human Cells |
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-... | |||
TMPY-01478 | HSP90 alpha Protein, Human, Recombinant | Human | E. coli |
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe... | |||
TMPY-04269 | LAP3 Protein, Human, Recombinant (His) | Human | HEK293 |
LAP3 (Leucine Aminopeptidase 3) is a Protein Coding gene. 2 alternative initiation human isoforms have been reported. LAP3, belonging to the peptidase M17 family, has been proved to catalyze the hydrolysis of leucine res... | |||
TMPY-00665 | Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) | Human | HEK293 |
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam... | |||
TMPY-02672 | Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Prostatic acid phosphatase (PAP, or ACPP), also known as prostatic specific acid phosphatase (PSAP), is an enzyme produced by the prostate. As a non-specific phosphomonoesterase, Prostatic acid phosphatase is synthesized... | |||
TMPY-06553 | CXCR4 Protein, Human, Recombinant | Human | HEK293 |
CXCR4 Protein, Human, Recombinant is expressed in HEK293. The predicted molecular weight is 39.75 kDa. Accession number: P61073-1 | |||
TMPY-02217 | HSC70 Protein, Human, Recombinant (His) | Human | E. coli |
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed m... | |||
TMPY-05521 | Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d... | |||
TMPY-06845 | HSP90 alpha Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe... | |||
TMPJ-00966 | GDF-5 Protein, Human, Recombinant | Human | E. coli |
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor... | |||
TMPY-03047 | Stathmin 1 Protein, Human, Recombinant (His) | Human | E. coli |
Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and ... | |||
TMPJ-00960 | TMPO Protein, Human, Recombinant (His) | Human | E. coli |
Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domai... | |||
TMPY-00570 | Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) | Human | Yeast |
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyro... | |||
TMPH-01344 | Flap endonuclease 1/FEN-1 Protein, Human, Recombinant (His & Myc) | Human | E. coli |
Structure-specific nuclease with 5'-flap endonuclease and 5'-3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displa... | |||
TMPY-01481 | FLAP Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP), also known as FLAP, belongs to the MAPEG family. ALOX5AP/FLAP is an essential partner of 5-LO for this process. The FLAP (ALOX5AP) gene has been linked to risk fo... | |||
TMPJ-01192 | ELAPOR1 Protein, Human, Recombinant (His) | Human | Human Cells |
Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated wi... | |||
TMPH-00648 | LapB Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of prote... | |||
TMPY-05717 | Integrin alpha V beta 8 Protein, Human, Recombinant (His) | Human | HEK293 |
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto... | |||
TMPJ-00258 | TGF beta 2 Protein, Human, Recombinant | Human | Human Cells |
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T... | |||
TMPH-00305 | TGF-beta 1 Protein, Bovine, Recombinant (His) | Bovine | E. coli |
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1,... | |||
TMPH-00382 | TGF-beta 1 Protein, Chicken, Recombinant (His & SUMO) | Chicken | E. coli |
Transforming growth factor beta-1 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-1 (TGF-beta-1) chains, which constitute the regulatory and active subunit of TGF-beta-1,... | |||
TMPH-00306 | TGF-beta 2 Protein, Bovine, Recombinant (His & Myc) | Bovine | E. coli |
Transforming growth factor beta-2 proprotein: Precursor of the Latency-associated peptide (LAP) and Transforming growth factor beta-2 (TGF-beta-2) chains, which constitute the regulatory and active subunit of TGF-beta-2,... | |||
TMPJ-00256 | Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | Human Cells |
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are... | |||
TMPJ-00255 | TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated | Human | Human Cells |
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are... | |||
TMPH-03206 | ITGB8 Protein, Rabbit, Recombinant (His & Myc) | Rabbit | E. coli |
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor b... | |||
TMPJ-00364 | LRRC32 Protein, Human, Recombinant (hFc) | Human | Human Cells |
Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency a... | |||
TMPH-02231 | NRROS Protein, Human, Recombinant (E. coli, His & Myc) | Human | E. coli |
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi... | |||
TMPH-02230 | NRROS Protein, Human, Recombinant (His & Myc) | Human | Baculovirus |
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi... | |||
TMPH-02803 | NRROS Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi... | |||
TMPJ-00802 | THBS1 Protein, Human, Recombinant (His) | Human | Human Cells |
Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and w... |