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Search Result

Search Results for " lap "

Targets

FLAP

111

Compounds

29

Natural Products

26

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T32568 LAP Lithium PTMB phosphinate
LAP is a photocrosslinker for hydrogels.
T16866 SDZ281-977 SDZ-LAP 977 Others
SDZ 281-977 is a derivative of Lavendustin A which is the EGF receptor tyrosine kinase inhibitor.
T83714 LAP TFA Lupus Autoantigen Peptide,La Peptide
Lupus autoantigen peptide (LAP), a derivative of the autoantigen La found in systemic lupus erythematosus (SLE) patients, spans amino acids 11-28 of La and functions as an antiviral peptide. It primarily blocks the hepat...
T1689 Enalapril IMpurity B (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine Others
Enalapril IMpurity B ((+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine) is Moexipril intermediate and is the main metabolite of Imidapril.
T1756L Ilaprazole IY81149,IY 81149,IY-81149 Proton pump , TOPK
Ilaprazole (IY-81149) is a proton pump inhibitor used in the treatment of dyspepsia gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. Studies also showed that Ilaprazole significantly prevented the developm...
T14390L (2R,3S)-Azelaprag Apelin receptor
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(...
T67799 Goxalapladib GSK 677116 Others
Goxalapladib（GSK 677116） is a small molecule compound that can be used to treat cardiovascular risks associated with atherosclerosis.
T83648 Tenilapine Others
Tenilapine is a neuroleptic compound that can be used to study atypical antipsychotics.
T1605 Enalapril MK-421 RAAS , MRP
Enalapril is a dicarbocyl-containing peptide and angiotensin-converting enzyme (ACE) inhibitor with antihypertensive activity.
T32253 Jalapinolic acid 11-Hydroxy Palmitic Acid,Builic Acid,Jalapinoic Acid,11-Hydroxyhexadecanoic acid Others
Jalapinolic acid (Builic Acid) is a hydroxypalmitic acid.
T6486 Enalapril Maleate MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate RAAS
Enalapril Maleate (MK-421 Maleate), an angiotensin-converting enzyme (ACE) inhibitor, is utilized in the treatment of hypertension, chronic heart failure , and diabetic nephropathy.
T16751 Rilapladib SB 659032 Phospholipase
Rilapladib (SB 659032) is a selective inhibitor of Lipoprotein-Associated Phospholipase A2(Lp-PLA2, IC50 = 230 pM) and an antagonist of the platelet activating factor receptor.
T35054 Vilaprisan BAY 1002670,BAY10-02670,BAY-1002670,BAY1002670,BAY-10-02670,BAY 10-02670 Progesterone Receptor
Vilaprisan (BAY 1002670) is a novel orally available and selective progesterone receptor modulator (SPRM) with antiproliferative activity against uterine fibroids (UF) and can be used for the study of uterine fibroids.
T6340 Enalaprilat Dihydrate MK-422,MK-422 Dihydrate RAAS , Autophagy
Enalaprilat Dihydrate (MK-422 Dihydrate) （IC50=1.94 nM） is a potent angiotensin-converting enzyme (ACE) inhibitor.
T1756 Ilaprazole sodium IY-81149 sodium Proton pump , TOPK
Ilaprazole sodium (IY-81149 sodium) , a substituted benzimidazole prodrug, is a selective and irreversible proton pump inhibitor. A weak base, Ilaprazole accumulates in the acidic environment of the secretory canaliculus...
TQ0113 Iclaprim AR-100 Antibacterial , Antibiotic
Iclaprim (AR-100) is a novel specific bacterial Dihydrofolate inhibitor. It can inhibit the growth of S. aureus (MIC90: 0.06 μg/mL).
T9023 Atuliflapon AZD5718 FLAP
Atuliflapon (AZD5718) is a novel 5-Lipoxygenase Activating Protein(FLAP) inhibitor for Treatment of Coronary Artery Disease.
T16732 Reproxalap NS-2,ADX-102 Others
Reproxalap (NS-2) covalently binds aldehydes including malondialdehyde and 4-hydroxynonenal. Reproxalap is a reactive aldehyde species sequestering agent for the treatment of the dry eye.
T11487 Fiboflapon GSK2190915,AM-803 FLAP
Fiboflapon (GSK2190915) is an orally available and effective 5-lipoxygenase-activating protein (FLAP) inhibitor that binds FLAP with a titer of 2.9 nM and inhibition of LTB4 in human blood with an IC50 of 76 nM.
T8844 Diflapolin Others , FLAP , Epoxide Hydrolase
Diflapolin is a highly active dual 5-lipoxygenase-activating protein (FLAP)/soluble epoxide hydrolase (sEH) inhibitor with marked anti-inflammatory efficacy and high target selectivity.
T6235 Lapatinib Ditosylate Lapatinib (GW-572016) Ditosylate,GW-572016 ditosylate,Tykerb ditosylate EGFR , Ferroptosis , Autophagy
Lapatinib Ditosylate (Tykerb ditosylate) is an effective EGFR and ErbB2 inhibitor (IC50: 10.8/9.2 nM for EGFR/ErbB2).
T3724 Rolapitant hydrochloride Rolapitant HCl Neurokinin receptor
Rolapitant (SCH619734) hydrochloride is a potent, selective, long-acting and orally active neurokinin 1 (NK1) receptor antagonist with a K i of 0.66 nM. Rolapitant hydrochloride (Rolapitant HCl) does not interact with CY...
T0078L Lapatinib ditosylate monohydrate Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,Tyverb EGFR , Ferroptosis , Autophagy
Lapatinib ditosylate (Lapatinib tosilate) monohydrate is a tyrosine kinase receptor inhibitor used in the therapy of advanced breast cancer and other solid tumors. Lapatinib ditosylate monohydrate therapy is associated w...
T5329 Trandolapril Angiotensin-converting Enzyme (ACE)
Trandolapril is an orally administered angiotensin converting enzyme (ACE) inhibitor that is hydrolysed to the active diacid trandolaprilat.
T27798 Lapisteride CS891B,CS-891,CS-891B,CS891 Others
Lapisteride (CS-891) a steroidal 5α-reductase inhibitor is used to treat benign prostatic hyperplasia (BPH) and androgenetic alopecia and may be effective in preventing or treating AGA .
T69013 Alaproclate NMDAR
Alaproclate is a non-competitive NMDA receptor antagonist and a new selective 5-HT uptake inhibitor for the study of depression and dementia.
T3716 Rolapitant SCH619734 Neurokinin receptor
Rolapitant (SCH619734) Hydrochloride is the hydrochloride salt form of rolapitant, an orally bioavailable, centrally-acting, selective, neurokinin 1 receptor (NK1-receptor) antagonist with potential antiemetic activity. ...
T77695 Muvalaplin LY3473329 Others
Muvalaplin (LY3473329) is an orally active lipoprotein (a) Lp(a) reagent that inhibits Lp(a) formation by blocking apo(a)-apo B100 interactions.
T22700 Cyclapolin 9 PLK
Cyclapolin 9 is a selective, potent, and ATP-competitive inhibitor of polo-like kinase 1 (PLK1) with an IC50 of 500 nM, and has not shown activity against other kinases.
T4510 Polaprezinc Zinc L-carnosine Others
Polaprezinc is an bioavailable chelate comprised of zinc and L-carnosine, known for its gastrointestinal protective properties, as well as its anti-ulcer, antioxidant, and anti-inflammatory effects.
T16087 Quiflapon MK-591 Apoptosis , FLAP
Quiflapon (MK-591) causes cell apoptosis. Quiflapon is a selective and specific 5-lipoxygenase-activating protein (FLAP) inhibitor (IC50: 1.6 nM in a FLAP binding assay) and is also an effective and orally active Leukotr...
T3281 Delapril hydrochloride indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317 RAAS
Delapril hydrochloride (indalapril) is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit angiotensin-converting enzyme...
T68090 Laprafylline Others
Laprafylline is a xanthine compound with inhibitory effects on bronchoconstriction in vivo and antitumor activity.Laprafylline acts as a competitive serotonergic antagonist at low concentrations, and inhibits constrictio...
T83647 (Z)-Tenilapine Others
(Z)-Tenilapine is trans-Tenilapine, cis-Tenilapine has sedative activity.
T14390 Azelaprag AMG 986 Apelin receptor
Azelaprag (AMG 986) is an effective small-molecule apelin receptor agonist. Azelaprag can be used to treat neurological diseases and cardiovascular diseases.
T30798 Cerlapirdine PF05212365,P -05212365,SAM-531,SAM531,PF-05212365,SAM 531,WAY-262,531 5-HT Receptor
Cerlapirdine (PF-05212365) is a selective, potent, full antagonist of the 5-hydroxytryptamine 6 (5-HT6) receptor. Cerlapirdine is already in clinical development for the treatment of cognitive disorders related to Alzhei...
T19862 Voxilaprevir HCV Protease
Voxilaprevir is an inhibitor of hepatitis C virus (HCV) nonstructural (NS) protein 3/4A protease.
T26085 Rilapine Rilapinum 5-HT Receptor
Rilapine (Rilapinum) is an antipsychotic compound that shows high affinity for 5-HT6 receptors and can be used to study neurological disorders.
T6190 Telaprevir VX-950,LY-570310,Incivek,MP-424 HCV Protease , SARS-CoV
Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).
T0078 Lapatinib GSK572016,GW572016 EGFR , Ferroptosis , Autophagy
Lapatinib (GW572016) is an inhibitor of ErbB2 and EGFR (IC50=9.2/10.8 nM) with oral activity. Lapatinib has antitumor activity and can be used to treat advanced or metastatic breast cancer with HER2 overexpression.
T3015 Olaparib AZD2281,KU0059436 Mitophagy , PARP , Autophagy
Olaparib (KU0059436) is a small molecule inhibitor of PARP1/PARP2 (IC50=5/1 nM), with weak inhibitory activity against PARP tankyrase-1 (IC50=1.5 μM), and is selective and orally active. Olaparib exhibits autophagy and m...
T20758 Trandolaprilat RU44403,RU-44403,Trandolaprilate,Trandolaprilatum,RU 44403
Trandolaprilat is an inhibitor of non-sulfhydryl angiotensin-converting enzyme.
T6340L Enalaprilat MK422,MK 422,MK 421 diacid,Enalapril acid,MK-422
Enalaprilat, the active metabolite of Enalapril, is a effective intravenously administered angiotensin-converting enzyme inhibitor. It is an effective agent for the treatment of essential hypertension and has beneficial ...
T25628 Lapyrium Lapyrium cation
Lapyrium is a cationic surfactant that is used in personal care products as a biocide and antistatic. It is also used by the chloride salt, lapyrium chloride, in waste-water treatment and corrosion inhibition formulation...
T78218 Ilaprazole sodium hydrate IY-81149 sodium hydrate Proton pump
Ilaprazole (IY-81149) sodium hydrate is an orally active proton pump inhibitor that irreversibly inhibits H+/K+-ATPase in rabbit parietal cells with a dose-dependent IC50 of 6 μM. It is employed in gastric ulcer research...
T16274 Narlaprevir SCH 900518 Others
Narlaprevir is an effective, selective, and orally bioavailable NS3 protease inhibitor(Ki=6 nM; EC90=40 nM).
T70255 Elapegademase
Elapegademase is an Adenosine Deaminase Inhibitor
T80532 Ac-AAVALLPAVLLALLAP-YVAD-CHO Caspase
Ac-AAVALLPAVLLALLAP-YVAD-CHO is a cell-permeable inhibitor of caspase-1 exhibiting antitumor activity [1].
T80378 Tilapia piscidin 3
Tilapia piscidin 3, an antimicrobial peptide, exhibits antibacterial properties effective against both gram-positive and gram-negative bacteria. It has demonstrated minimum inhibitory concentrations (MICs) of 2.44 µg/mL ...
T80536 Ac-AAVALLPAVLLALLAP-LEVD-CHO Caspase
Ac-AAVALLPAVLLALLAP-LEVD-CHO is a cell-permeable inhibitor of caspase-4 that exhibits antitumor activity [1].

Compounds

LAP
T32568
Synonym: Lithium PTMB phosphinate
Target:
SDZ281-977
T16866
Synonym: SDZ-LAP 977
Target: Others
LAP TFA
T83714
Synonym: Lupus Autoantigen Peptide,La Peptide
Target:
Enalapril IMpurity B
T1689
Synonym: (+)-N-[1-(S)-Ethoxycarbonxyl-3-phenylpropyl]-L-alanine
Target: Others
Ilaprazole
T1756L
Synonym: IY81149,IY 81149,IY-81149
Target: Proton pump, TOPK
(2R,3S)-Azelaprag
T14390L
Synonym:
Target: Apelin receptor
Goxalapladib
T67799
Synonym: GSK 677116
Target: Others
Tenilapine
T83648
Synonym:
Target: Others
Enalapril
T1605
Synonym: MK-421
Target: RAAS, MRP
Jalapinolic acid
T32253
Synonym: 11-Hydroxy Palmitic Acid,Builic Acid,Jalapinoic Acid,11-Hydroxyhexadecanoic acid
Target: Others
Enalapril Maleate
T6486
Synonym: MK-421 Maleate,Renitec Maleate,Glioten Maleate,MK-421 (maleate),Vasotec Maleate
Target: RAAS
Rilapladib
T16751
Synonym: SB 659032
Target: Phospholipase
Vilaprisan
T35054
Synonym: BAY 1002670,BAY10-02670,BAY-1002670,BAY1002670,BAY-10-02670,BAY 10-02670
Target: Progesterone Receptor
Enalaprilat Dihydrate
T6340
Synonym: MK-422,MK-422 Dihydrate
Target: RAAS, Autophagy
Ilaprazole sodium
T1756
Synonym: IY-81149 sodium
Target: Proton pump, TOPK
Iclaprim
TQ0113
Synonym: AR-100
Target: Antibacterial, Antibiotic
Atuliflapon
T9023
Synonym: AZD5718
Target: FLAP
Reproxalap
T16732
Synonym: NS-2,ADX-102
Target: Others
Fiboflapon
T11487
Synonym: GSK2190915,AM-803
Target: FLAP
Diflapolin
T8844
Synonym:
Target: Others, FLAP, Epoxide Hydrolase
Lapatinib Ditosylate
T6235
Synonym: Lapatinib (GW-572016) Ditosylate,GW-572016 ditosylate,Tykerb ditosylate
Target: EGFR, Ferroptosis, Autophagy
Rolapitant hydrochloride
T3724
Synonym: Rolapitant HCl
Target: Neurokinin receptor
Lapatinib ditosylate monohydrate
T0078L
Synonym: Lapatinib ditosylate monohydrate,Lapatinib ditoluenesulfonate monohydrate,Lapatinib tosilate hydrate,Lapatinib tosilate,Tykerb,Tyverb
Target: EGFR, Ferroptosis, Autophagy
Trandolapril
T5329
Synonym:
Target: Angiotensin-converting Enzyme (ACE)
Lapisteride
T27798
Synonym: CS891B,CS-891,CS-891B,CS891
Target: Others
Alaproclate
T69013
Synonym:
Target: NMDAR
Rolapitant
T3716
Synonym: SCH619734
Target: Neurokinin receptor
Muvalaplin
T77695
Synonym: LY3473329
Target: Others
Cyclapolin 9
T22700
Synonym:
Target: PLK
Polaprezinc
T4510
Synonym: Zinc L-carnosine
Target: Others
Quiflapon
T16087
Synonym: MK-591
Target: Apoptosis, FLAP
Delapril hydrochloride
T3281
Synonym: indalapril,Alindapril Hydrochloride,Delapril Hydrochloride,CV 3317
Target: RAAS
Laprafylline
T68090
Synonym:
Target: Others
(Z)-Tenilapine
T83647
Synonym:
Target: Others
Azelaprag
T14390
Synonym: AMG 986
Target: Apelin receptor
Cerlapirdine
T30798
Synonym: PF05212365,P -05212365,SAM-531,SAM531,PF-05212365,SAM 531,WAY-262,531
Target: 5-HT Receptor
Voxilaprevir
T19862
Synonym:
Target: HCV Protease
Rilapine
T26085
Synonym: Rilapinum
Target: 5-HT Receptor
Telaprevir
T6190
Synonym: VX-950,LY-570310,Incivek,MP-424
Target: HCV Protease, SARS-CoV
Lapatinib
T0078
Synonym: GSK572016,GW572016
Target: EGFR, Ferroptosis, Autophagy
Olaparib
T3015
Synonym: AZD2281,KU0059436
Target: Mitophagy, PARP, Autophagy
Trandolaprilat
T20758
Synonym: RU44403,RU-44403,Trandolaprilate,Trandolaprilatum,RU 44403
Target:
Enalaprilat
T6340L
Synonym: MK422,MK 422,MK 421 diacid,Enalapril acid,MK-422
Target:
Lapyrium
T25628
Synonym: Lapyrium cation
Target:
Ilaprazole sodium hydrate
T78218
Synonym: IY-81149 sodium hydrate
Target: Proton pump
Narlaprevir
T16274
Synonym: SCH 900518
Target: Others
Elapegademase
T70255
Synonym:
Target:
Ac-AAVALLPAVLLALLAP-YVAD-CHO
T80532
Synonym:
Target: Caspase
Tilapia piscidin 3
T80378
Synonym:
Target:
Ac-AAVALLPAVLLALLAP-LEVD-CHO
T80536
Synonym:
Target: Caspase
1 2 3
Cat No. Product Name Synonyms Targets
T6560 Lappaconitine hydrobromide Lappaconite HBr,Allapinine Others
Lappaconitine hydrobromide (Allapinine) is a kind of alkaloid extracted from Aconitum sinomontanum Nakai. It has anti-inflammatory effects.
T5690 7,4'-Di-O-methylapigenin 4',7-DIMETHOXY-5-HYDROXYFLAVONE Amylase
7,4'-Di-O-methylapigenin (4',7-DIMETHOXY-5-HYDROXYFLAVONE) can inhibit α-glucosidase and α-amylase enzymes and enhance 2-NBDG uptake in L6 cells, it has hypolipidemic effect on mouse pre-adipocyte (3T3L1) cell lines.
TN1569 Deoxylapachol Antifection , Antifungal
Deoxylapachol has anti-wood rot activity, it can inhibit the brown rot fungi Gloeophyllum sepiarium CBS 353.74 and Gloeophyllum trabeum CBS 318.50 and the white rot fungi Merulius tremellosus CBS 280.73 and Phlebia brevi...
T32570 Lappaconine 20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine Others
Lappaconine (20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol) derivated from norditerpenoid alkaloids.
T4136 Lapachol Bethabarra wood,CI75490,Greenhartin,Tecomin Others , Influenza Virus , Antibacterial , Parasite , Antifungal
Lapachol (CI75490) has antimicrobial properties against many pathogens. It has anti-inflammatory, analgesic and antibiotic properties. It is an inhibitor of epithelial tumors in Drosophila melanogaster heterozygote.
T6407 β-Lapachone Beta-Lapachone,NSC-26326,SL-11001,ARQ-501 IDO , Apoptosis , Topoisomerase , Autophagy
β-Lapachone (ARQ-501) is a specific DNA topoisomerase I inhibitor, and no inhibitory activities against DNA topoisomerase II or ligase.
T2806 Lappaconitine (+)-Lappaconitine P2X Receptor , Sodium Channel
Lappaconitine ((+)-Lappaconitine), isolated from Aconitum sinomontanum Nakai, was characterized as an analgesic.
TN7058 Dihydrolapachenole 6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene Others
Dihydrolapachenole (6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene) can be isolated from T. chrysantha.
TN1375 α-Lapachone alpha-Lapachone Topoisomerase , Antifection
α-Lapachone has antineoplastic activity, it shows an approximately trypanocidal activity against Trypanosoma cruzi.
TN6461 Isolappaol A
Isolappaol A is a natural product for research related to life sciences. The catalog number is TN6461 and the CAS number is 131400-96-9.
TN3620 Celaphanol A NF-κB
Celaphanol A shows moderate inhibition in both NF-κB activation and nitric oxide production, suggests that it is a possible inhibitor of the NF-kappaB pathway and has antiinflammatory activity.
TN5875 6′′-O-β-D-Apiofuranosylapterin
6′′-O-β-D-Apiofuranosylapterin is a natural product for research related to life sciences. The catalog number is TN5875 and the CAS number is 2188162-94-7.
TN6463 Lappaol B
Lappaol B is a natural product for research related to life sciences. The catalog number is TN6463 and the CAS number is 62359-60-8.
TN2987 3Alaph-Tigloyloxypterokaurene L3 Others
3Alaph-Tigloyloxypterokaurene L3 is a natural product from Wedelia trilobata.
TN3212 7,4-Di-O-methylapigenin 5-O-glucoside Others
7,4-Di-O-methylapigenin 5-O-glucoside is a natural product for research related to life sciences. The catalog number is TN3212 and the CAS number is 197018-71-6.
TN4410 Lappaol C P-gp , JNK
Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidat...
TN3213 7,4'-Di-O-methylapigenin 5-O-xylosylglucoside Others
7,4'-Di-methylapigenin-5-O-xylosylglucoside shows inhibitory activity for nitric oxide(NO) production by activated RAW 264.7 cells.
TN6199 Atalaphylline
Atalaphylline is a natural product for research related to life sciences. The catalog number is TN6199 and the CAS number is 28233-35-4.
TN3318 9-Hydroxy-alpha-lapachone Antifection
9-Hydroxy-alpha-lapachone can highly inhibit the growth of H. pylori, it exhibits potent inhibitory activity against H. pylori Cystathionine gamma-synthase, with IC(50) values of 4.64 microM. It may have anti-inflammator...
T65249 Hydroxylapatite
Hydroxylapatite is a natural product for research related to life sciences and the catalog number is T65249.
TN6462 Isolappaol C
Isolappaol C is a natural product for research related to life sciences. The catalog number is TN6462 and the CAS number is 929905-15-7.
TN3019 4,9-Dihydroxy-alpha-lapachone Others
4,9-Dihydroxy-alpha-lapachone has antitumor-promoting effects, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein-Barr virus early antigen (EBV-EA) activation i...
TN6152 N-Methylatalaphylline
N-Methylatalaphylline is a natural product for research related to life sciences. The catalog number is TN6152 and the CAS number is 28233-34-3.
TN3321 9-Methoxy-alpha-lapachone Others
9-Methoxy-alpha-lapachone has antitumor-promoting effect, it exhibits significant inhibitory activity against 12-O-tetradecanoylphorbol 13-acetate (TPA)-induced Epstein- Barr virus early antigen (EBV-EA) activation in Ra...
TN4411 Lappaol F CDK , P-gp , JNK
1. Lappaol F has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. <br/> 2. Lappaol F has potential chemosensitizing activity, it may be c...
TN3264 8,3'-Diprenylapigenin Others
8,3'-Diprenylapigenin is a natural product for research related to life sciences. The catalog number is TN3264 and the CAS number is 955135-37-2.
TN1072 Lappaol A P-gp , JNK
Lappaol A has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol A also has potential chemosensitizing activity, it may be candidat...
T83284 5-O-Primeverosylapigenin
5-O-Primeverosylapigenin, a member of the primeverosylapigenin class, can be isolated from species within the Gentianaceae family [1].
T6S1315 Oroxylin A 6-Methoxybaicalein,Baicalein 6-methyl ether Virus Protease , HIF/HIF Prolyl-Hydroxylase , Autophagy
1. Oroxylin A (Baicalein 6-methyl ether) has various anti-tumor effects including apoptosis, cell cycle arrest, drug-resistant reversion. 2. Oroxylin A possesses abilities of inhibiting the ATRA-induced IL-6 production v...

Natural Products

Lappaconitine hydrobromide
T6560
Synonym: Lappaconite HBr,Allapinine
Target: Others
7,4'-Di-O-methylapigenin
T5690
Synonym: 4',7-DIMETHOXY-5-HYDROXYFLAVONE
Target: Amylase
Deoxylapachol
TN1569
Synonym:
Target: Antifection, Antifungal
Lappaconine
T32570
Synonym: 20-ethyl-1,14,16-trimethoxyaconitane-4,6,8-triol,O(sup 1)-Methyllappaconidine
Target: Others
Lapachol
T4136
Synonym: Bethabarra wood,CI75490,Greenhartin,Tecomin
Target: Others, Influenza Virus, Antibacterial, Parasite, Antifungal
β-Lapachone
T6407
Synonym: Beta-Lapachone,NSC-26326,SL-11001,ARQ-501
Target: IDO, Apoptosis, Topoisomerase, Autophagy
Lappaconitine
T2806
Synonym: (+)-Lappaconitine
Target: P2X Receptor, Sodium Channel
Dihydrolapachenole
TN7058
Synonym: 6-methoxy-2,2-dimethyl-3,4-dihydro-2H-benzo[h]chromene
Target: Others
α-Lapachone
TN1375
Synonym: alpha-Lapachone
Target: Topoisomerase, Antifection
Isolappaol A
TN6461
Synonym:
Target:
Celaphanol A
TN3620
Synonym:
Target: NF-κB
6′′-O-β-D-Apiofuranosylapterin
TN5875
Synonym:
Target:
Lappaol B
TN6463
Synonym:
Target:
3Alaph-Tigloyloxypterokaurene L3
TN2987
Synonym:
Target: Others
7,4-Di-O-methylapigenin 5-O-glucoside
TN3212
Synonym:
Target: Others
Lappaol C
TN4410
Synonym:
Target: P-gp, JNK
7,4'-Di-O-methylapigenin 5-O-xylosylglucoside
TN3213
Synonym:
Target: Others
Atalaphylline
TN6199
Synonym:
Target:
9-Hydroxy-alpha-lapachone
TN3318
Synonym:
Target: Antifection
Hydroxylapatite
T65249
Synonym:
Target:
Isolappaol C
TN6462
Synonym:
Target:
4,9-Dihydroxy-alpha-lapachone
TN3019
Synonym:
Target: Others
N-Methylatalaphylline
TN6152
Synonym:
Target:
9-Methoxy-alpha-lapachone
TN3321
Synonym:
Target: Others
Lappaol F
TN4411
Synonym:
Target: CDK, P-gp, JNK
8,3'-Diprenylapigenin
TN3264
Synonym:
Target: Others
Lappaol A
TN1072
Synonym:
Target: P-gp, JNK
5-O-Primeverosylapigenin
T83284
Synonym:
Target:
Oroxylin A
T6S1315
Synonym: 6-Methoxybaicalein,Baicalein 6-methyl ether
Target: Virus Protease, HIF/HIF Prolyl-Hydroxylase, Autophagy

Recombinant Proteins

Species：
Human (21)
Mouse (2)
E. coli (1)
Human,Mouse,Rat (1)
Rabbit (1)
Expression System：
HEK293 Cells (14)
E. coli (9)
Baculovirus Insect Cells (2)
P. pastoris (Yeast) (1)
Tag：
His (7)
Tag Free (5)
C-His (3)
C-6xHis (2)
N-10xHis, C-Myc (2)
N-6xHis (2)
C-10xHis (1)
C-hFc (1)
N-6xHis-Avi (1)
N-Avi (1)
Cat No. Product Name Species Expression System
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPJ-00254 TGF beta 3 Protein, Human/Mouse/Rat, Recombinant Human,Mouse,Rat HEK293 Cells
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated Human HEK293 Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPY-01478 HSP90 alpha Protein, Human, Recombinant Human E. coli
HSP90 alpha Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 22.6 kDa and the accession number is K9JA46.
TMPY-04269 LAP3 Protein, Human, Recombinant (His) Human HEK293 Cells
LAP3 (Leucine Aminopeptidase 3) is a Protein Coding gene. 2 alternative initiation human isoforms have been reported. LAP3, belonging to the peptidase M17 family, has been proved to catalyze the hydrolysis of leucine res...
TMPY-00665 Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) Human HEK293 Cells
Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 104.2 kDa and the accession number is A0A024RC61.
TMPY-02672 Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42 kDa and the accession number is Q8CE08-1.
TMPY-06553 CXCR4 Protein, Human, Recombinant Human HEK293 Cells
CXCR4 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 39.75 kDa and the accession number is P61073-1.
TMPY-02217 HSC70 Protein, Human, Recombinant (His) Human E. coli
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed m...
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated Human HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2.
TMPJ-00966 GDF-5 Protein, Human, Recombinant Human E. coli
Growth Differentiation Factor 5(GDF-5, BMP-14) is a member of the BMP family of TGFβ superfamily proteins. Human GDF-5, -6, and -7 are a defined subgroup of the BMP family. GDF-5 is synthesized as a homodimeric precursor...
TMPY-06845 HSP90 alpha Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
HSP90 alpha Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 87.06 kDa and the accession number is NP_005339.3.
TMPY-03047 Stathmin 1 Protein, Human, Recombinant (His) Human E. coli
Stathmin1 (STMN1) is a cytosolic phosphoprotein that regulates cellular microtubule dynamics and is known to have oncogenic activity. STMN1 is a possible biomarker for paclitaxel sensitivity and poor prognosis in GC and ...
TMPJ-00960 TMPO Protein, Human, Recombinant (His) Human E. coli
Thymopentin is a member of the LEM family. Thymopentin is expressed in many tissues, highly in the adult thymus and fetal liver. The N-terminal contains two structurally independent domains, LEM domain and LEM-like domai...
TMPY-00570 Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
Most importantly, placental alkaline phosphatase (ALPP), an ectoenzyme that locates on cell surface with catalytic domains outside the plasma membrane and is overexpressed on many cancer cells, dephosphorylate the d-tyro...
TMPJ-01192 ELAPOR1 Protein, Human, Recombinant (His) Human HEK293 Cells
Endosome/lysosome-associated apoptosis and autophagy regulator (ELAPOR1), also known as EIG121 protein, is a type I transmembrane protein induced by estrogen. The estrogen-induced gene 121 (EIG121) has been associated wi...
TMPY-01481 FLAP Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
Arachidonate 5-Lipoxygenase-Activating Protein (ALOX5AP), also known as FLAP, belongs to the MAPEG family. ALOX5AP/FLAP is an essential partner of 5-LO for this process. The FLAP (ALOX5AP) gene has been linked to risk fo...
TMPH-01344 Flap endonuclease 1/FEN-1 Protein, Human, Recombinant (His & Myc) Human E. coli
Flap endonuclease 1/FEN-1 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 50.0 kDa and the accession number is P39748.
TMPH-00648 LapB Protein, E. coli, Recombinant (His) E. coli E. coli
Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of prote...
TMPY-05717 Integrin alpha V beta 8 Protein, Human, Recombinant (His) Human HEK293 Cells
Integrin alpha V beta 8 is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. ITGAVB8 does not appear to assume different activation states; and the cytoplasmic tail does not connect to the cyto...
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant Human HEK293 Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPH-03206 ITGB8 Protein, Rabbit, Recombinant (His & Myc) Rabbit E. coli
Integrin alpha-V:beta-8 (ITGAV:ITGB8) is a receptor for fibronectin. It recognizes the sequence R-G-D in its ligands. Integrin alpha-V:beta-6 (ITGAV:ITGB6) mediates R-G-D-dependent release of transforming growth factor b...
TMPJ-00364 LRRC32 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Leucine Rich Repeat Containing 32 (LRRC32), also known as Glycoprotein A Repetitions Predominant (GARP), has been postulated as a novel surface marker of activated T(regs). LRRC32 binds directly to the TGF-beta latency a...
TMPH-02803 NRROS Protein, Mouse, Recombinant (His) Mouse E. coli
Key regulator of transforming growth factor beta-1 (TGFB1) specifically required for microglia function in the nervous system. Required for activation of latent TGF-beta-1 in macrophages and microglia: associates specifi...
TMPJ-00802 THBS1 Protein, Human, Recombinant (His) Human HEK293 Cells
Thrombospondin-1 (TSP-1) is a 150-180kDa calcium-sensitive protein that is secreted as a disulfide-linked homotrimer. TSP-1 regulates a wide range of cellular functions including their interactions with other cells and w...
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00250
Species: Human
Expression System: HEK293 Cells
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TMPJ-00254
Species: Human,Mouse,Rat
Expression System: HEK293 Cells
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293 Cells
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00249
Species: Human
Expression System: HEK293 Cells
HSP90 alpha Protein, Human, Recombinant
TMPY-01478
Species: Human
Expression System: E. coli
LAP3 Protein, Human, Recombinant (His)
TMPY-04269
Species: Human
Expression System: HEK293 Cells
Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)
TMPY-00665
Species: Human
Expression System: HEK293 Cells
Prostatic Acid Phosphatase Protein, Mouse, Recombinant (His)
TMPY-02672
Species: Mouse
Expression System: HEK293 Cells
CXCR4 Protein, Human, Recombinant
TMPY-06553
Species: Human
Expression System: HEK293 Cells
HSC70 Protein, Human, Recombinant (His)
TMPY-02217
Species: Human
Expression System: E. coli
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05521
Species: Human
Expression System: HEK293 Cells
GDF-5 Protein, Human, Recombinant
TMPJ-00966
Species: Human
Expression System: E. coli
HSP90 alpha Protein, Human, Recombinant (His)
TMPY-06845
Species: Human
Expression System: Baculovirus Insect Cells
Stathmin 1 Protein, Human, Recombinant (His)
TMPY-03047
Species: Human
Expression System: E. coli
TMPO Protein, Human, Recombinant (His)
TMPJ-00960
Species: Human
Expression System: E. coli
Alkaline Phosphatase/PLAP Protein, Human, Recombinant (His)
TMPY-00570
Species: Human
Expression System: P. pastoris (Yeast)
ELAPOR1 Protein, Human, Recombinant (His)
TMPJ-01192
Species: Human
Expression System: HEK293 Cells
FLAP Protein, Human, Recombinant (His)
TMPY-01481
Species: Human
Expression System: Baculovirus Insect Cells
Flap endonuclease 1/FEN-1 Protein, Human, Recombinant (His & Myc)
TMPH-01344
Species: Human
Expression System: E. coli
LapB Protein, E. coli, Recombinant (His)
TMPH-00648
Species: E. coli
Expression System: E. coli
Integrin alpha V beta 8 Protein, Human, Recombinant (His)
TMPY-05717
Species: Human
Expression System: HEK293 Cells
TGF beta 2 Protein, Human, Recombinant
TMPJ-00258
Species: Human
Expression System: HEK293 Cells
ITGB8 Protein, Rabbit, Recombinant (His & Myc)
TMPH-03206
Species: Rabbit
Expression System: E. coli
LRRC32 Protein, Human, Recombinant (hFc)
TMPJ-00364
Species: Human
Expression System: HEK293 Cells
NRROS Protein, Mouse, Recombinant (His)
TMPH-02803
Species: Mouse
Expression System: E. coli
THBS1 Protein, Human, Recombinant (His)
TMPJ-00802
Species: Human
Expression System: HEK293 Cells
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