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Cat No. | Product Name | Synonyms | Targets |
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T60850 | MIF-IN-2 | Others | |
MIF-IN-2 is a heterocyclic macrophage migration inhibitory factor (MIF) inhibitor with anticancer activity for the study of cancer and autoimmune disorders.CAS 번호13460-73-86-5 | |||
T3680 | ISO-1 | MIF Antagonist,ISO 1 | Others |
ISO-1 (MIF Antagonist) is an inhibitor of the dopachrome tautomerase activity, blocks the activation of NF-κB and TNF-α secretion from LPS-treated macrophages. | |||
T62344 | MIF-IN-3 | ||
MIF-IN-3 is an inhibitor of migration inhibitory factor (MIF), which can be used in the study of immunoinflammation-related diseases. | |||
T61218 | MIF-IN-5 | ||
MIF-IN-5 (compound 1d) is a highly effective and reversible competitive inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC 50 of 4.8 μM and a Ki value of 3.3 μM [1]. | |||
T60809 | MIF-IN-1 | ||
MIF-IN-1 (compound 14) is a potent inhibitor of macrophage migration inhibitory factor (MIF) with pIC50 of 6.87. Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine associated with multiple disease... | |||
T69525 | MIF degrader MD13 | ||
MIF degrader MD13 is involved in protein-protein interactions that play key roles in inflammation and cancer. Current strategies to develop small molecule modulators of MIF functions are mainly restricted to the MIF taut... | |||
T61705 | MIF-IN-6 | ||
MIF-IN-6 (compound 2d) is an effective inhibitor of macrophage migration inhibitory factor (MIF), exhibiting an IC50 of 1.4 μM and a Ki value of 0.96 μM. MIF-IN-6 effectively reduces MIF-induced ERK phosphorylation and i... | |||
T73676 | MIF-1 TFA | ||
MIF-1 TFA (Melanostatin), an intrinsic brain peptide, serves as a powerful allosteric modulator of the dopamine receptor. It plays a crucial role in regulating melanin production and modifies the analgesic efficacy by in... | |||
T76186 | Tyr-W-MIF-1 | ||
Tyr-W-MIF-1, an opioid tetrapeptide, exhibits both opiate and antiopiate activities, and has been demonstrated to induce analgesia [1] [2] [5]. | |||
T63322 | MIF-IN-4 hydrochloride | ||
MIF-IN-4 hydrochloride is a potent inhibitor of macrophage mobility inhibitory factor (MIF) with pIC50 values ranging from 5.01-6. Where MIF was originally discovered as a cytokine in the process of inhibiting macrophage... | |||
T7844 | 4-IPP | 4-Iodo-6-phenylpyrimidine | Others |
4-IPP (4-Iodo-6-phenylpyrimidine) is an irreversible inhibitor of macrophage migration inhibitory factor (MIF) | |||
TP1127L1 | Nemifitide acetate(173240-15-8 free base) | INN 00835 acetate | 5-HT Receptor |
Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF). | |||
T60388 | MIF098 | Others | |
MIF098 is a macrophage migration inhibitory factor (MIF) antagonist.MIF098, inhibits pulmonary hypertension associated with SLE and inhibits pulmonary smooth muscle cell (PASMC) proliferation and migration.MIF098 may be ... | |||
T16074 | Mifobate | SR-202 | PPAR |
Mifobate (SR-202) is a potent and specific antagonist of PPARγ. Mifobate shows antiobesity, antidiabetic and antiatherosclerotic effects[1]. | |||
T23372 | SMIFH2 | Others | |
SMIFH2 is formin homology 2 (FH2) domains inhibitor. | |||
T71973 | Gilteritinib hemifumarate | ASP2215 hemifumarate | FLT , TAM Receptor |
Gilteritinib hemifumarate (ASP2215 hemifumarate) is a potent ATP-competitive dual FLT3 (IC50: 0.29 nM) and AXL (IC50: 0.73 nM) inhibitor for the treatment of relapsed or refractory FLT3 mutant AML. | |||
T1492 | Gemifloxacin mesylate | LB-20304a,SB-265805S,Gemifloxacin mesylate | DNA gyrase , Topoisomerase , Antibacterial |
Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Mesylate is the mesylate salt form of... | |||
T6381 | Amifostine trihydrate | Ethyol trihydrate,WR2721,Amifostine | Others , HIF/HIF Prolyl-Hydroxylase |
Amifostine trihydrate (WR2721) is the first approved radioprotective drug, used to decrease the risk of kidney problems caused by treatment with cisplatin. | |||
T8623 | TMIFRY8XAG | 1,1'-(4-CHLOROBUTYLIDENE)BIS(4-FLUOROBENZENE),4-oxo-1,4-dihydroquinoline-2-carboxylic acid | Others |
TMIFRY8XAG (4-oxo-1,4-dihydroquinoline-2-carboxylic acid) is a derivative of Zerumbone with potential anti-tumor effects towards HeLa cancer cells. | |||
T4497 | Amifampridine | 3,4-Pyridinediamine,Pyridine-3,4-Diamine,3,4-Diaminopyridine | Others |
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is ... | |||
T17254 | Amifloxacin | Win49375 | Antibacterial |
Amifloxacin (Win49375) is a synthetic antibacterial compound and showed moderate activity against Staphylococcus aureus, with MICs of less than or equal to 2 micrograms/ml. | |||
TQ0133 | Amifostine thiol dihydrochloride | WR 1065 | p53 |
Amifostine thiol dihydrochloride (WR 1065) can activate p53 through a JNK-dependent signaling pathway. It also protects normal tissues from the toxic effects of certain cancer drugs. | |||
T2065 | Bioymifi | DR5 Activator | Apoptosis , TNF |
Bioymifi (DR5 Activator) is a novel and potent small-molecule activator of the TRAIL receptor DR5 in human cancer cells. | |||
T23536 | Xamoterol hemifumarate | ICI 118587 hemifumarate,Corwin hemifumarate | Adrenergic Receptor |
Xamoterol hemifumarate is a potent and selective β1-adrenoceptor agonist.Xamoterol hemifumarate is a potential compound for the study of the relationship between cardiac arrhythmias and β1-adrenergic stimulation with IKr... | |||
T4640 | Parimifasor | LYC30937 | Others |
Parimifasor (LYC30937) is an immunomodulator, with anti-inflammatory activity. | |||
T33876L1 | Panomifene TFA | Panomifene TFA(77599-17-8 Free base),EGIS5650 TFA,GYKl13504 TFA | Estrogen/progestogen Receptor |
Panomifene TFA(GYKl13504 TFA) is a small molecule antagonist of ERs with anticancer activity that can be used to study breast cancer and musculoskeletal diseases. | |||
T68100 | Mifentidine | DA 4577 | Histamine Receptor |
Mifentidine (DA 4577) is an orally available H2 receptor antagonist for the study of gastric emptying and experimental gastric and duodenal ulcers. | |||
T7308 | Nomifensine | NOMIFENSINE MALEATE,(±)-Nomifensin | Dopamine Receptor |
Nomifensine ((±)-Nomifensin) is a norepinephrine-dopamine reuptake inhibitor that prevents dopamine reuptake into synaptosomes. | |||
T67816 | Alamifovir PM | ||
Alamifovir PM is an analogue of Alamifovir, an HBV-specific antiviral compound. | |||
T7282 | Tenofovir alafenamide hemifumarate | GS-7340 (hemifumarate),Tenofovir alafenamide fumarate | HIV Protease , Reverse Transcriptase |
Tenofovir alafenamide hemifumarate (GS-7340 hemifumarate) is an oral phosphonoamidate prodrug of the HIV reverse transcriptase nucleotide inhibitor tenofovir (TFV) | |||
T20953 | Lumiflavine | Lumilactoflavin,Lumiflavin | Others |
Lumiflavine (Lumilactoflavin) inhibits riboflavin uptake. It is produced by the photolysis of vitamin B2. | |||
T8589 | (±)-Amiflamine | 4-(dimethylamino)-alpha,Amiflamine,2-dimethylphenethylamine | MAO , Monoamine Oxidase |
(±)-Amiflamine (2-dimethylphenethylamine) is an inhibitor of reversible MAO-A. | |||
T13385 | Zamifenacin fumarate | UK-76654 fumarate | AChR |
Zamifenacin fumarate (UK-76654 fumarate) is a potent and gut-selective antagonist of muscarinic M3 receptor. | |||
T37538 | Amifostine thiol | ||
Amifostine thiol (WR-1065), the active metabolite of cytoprotector Amifostine, serves as a cytoprotective agent possessing radioprotective properties. It activates p53 via a JNK-dependent signaling pathway[1][2][3]. | |||
T3289 | Amifostine | Ethyol,WR2721,Gammaphos | Others , HIF/HIF Prolyl-Hydroxylase |
Amifostine (Ethyol) anhydrous is a cytoprotective agent, acts as a free radical scavenging activity. | |||
T21979 | P32/98 (hemifumarate) | ||
P32/98 hemifumarateis a potent inhibitor of dipeptidyl peptidase IV with a K i value of 130 nM. P32/98 hemifumarate improves glucose tolerance, insulin sensitivity and β-cell responsiveness in fatty Zucker rat model. P32... | |||
T39520 | Vamifeport | VIT-2763 | Ferroptosis |
Vamifeport (VIT-2763) is a novel orally active inhibitor that targets iron transport proteins and reduces markers of hemolysis in the SCD Townes model.VIT-2763 improves anemia and erythropoiesis, ameliorates vascular inf... | |||
T7070 | Nomifensine maleate | Nomifensine (maleate),(±)-Nomifensine maleat | Dopamine Receptor |
Nomifensine maleate (Nomifensine (maleate)) is a selective inhibitor of dopamine uptake. Nomifensine maleate is used in adult attention deficit disorder. | |||
T33876L | Panomifene HCl | EGIS5650 HCl,GYKI 13504 HCl,Panomifene HCl(77599-17-8 Free base),EGIS 5650 HCl | HER |
Panomifene HCl is a selective anti-estrogenic compound with antitumor activity for the treatment of breast cancer. | |||
T27322 | Fispemifene | HM-101,HM 101,HM101 | Others |
Fispemifene (HM-101) is an estrogen receptor modulator (SERM) used to treat genitourinary syndromes and vaginal atrophy. | |||
T0104 | Umifenovir hydrochloride | Arbidol hydrochloride,Arbidol HCl | SARS-CoV , Influenza Virus |
Umifenovir hydrochloride (Arbidol HCl) , an broad-spectrum antiviral chemical agent, can inhibit cell invade of enveloped viruses by blocking viral fusion with host cell membrane. | |||
T1102 | Mifepristone | C-1073,RU486,RU 38486 | Glucocorticoid Receptor , Estrogen/progestogen Receptor , Progesterone Receptor , NO Synthase , Autophagy |
Mifepristone (C-1073) is a Progestin Antagonist. The mechanism of action of mifepristone is as a Progestational Hormone Receptor Antagonist. | |||
T1520 | Aliskiren hemifumarate | CGP 60536,SPP 100,CGP60536B | RAAS , Autophagy |
Aliskiren hemifumarate (CGP60536B) is an orally active nonpeptide renin inhibitor with antihypertensive activity. | |||
T6241 | Quetiapine hemifumarate | Quetiapine Fumarate,ICI-204636 | Dopamine Receptor , 5-HT Receptor , Adrenergic Receptor |
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression. | |||
TP1127 | Nemifitide diTFA | INN 00835 diTFA | 5-HT Receptor |
Nemifitide diTFA (INN 00835 diTFA) is a synthetic pentapeptide, a peptide like melanocyte suppressor factor (MIF) that can cross the blood-brain barrier and has potent antidepressant activity. | |||
T63169 | MIF2-IN-1 | ||
MIF2-IN-1 (compound 5d) is a potent MIF2 tautomerase inhibitor (IC50: 1.0 μM). MIF2-IN-1 inhibits the proliferation of non-small cell lung cancer cells by arresting the cell cycle through the MAPK pathway. MIF2-IN-1 has ... | |||
T25608 | Lamifiban trifluoroacetate | Lamifiban trifluoroacetate salt | |
Lamifiban trifluoroacetate is an antagonist of the nonpeptide platelet fibrinogen receptor (GPIIb/IIIa). | |||
T20662 | Gemifloxacin | SB-265805,SB 265805,SB265805 | |
Gemifloxacin is a fluoronaphthyridone with strong antibacterial effect. | |||
T4497L | Amifampridine phosphate | BRN0110232,3,6-DAP,SC10,BRN 0110232,BRN-0110232,NSC 521760 | |
Amifampridine is mainly used to treat many rare muscle diseases. In the United States, aminopyridine is being studied for the treatment of Lambert-Eaton myasmus syndrome (LEMS). Amifampridine is also used to treat many c... | |||
T12329 | Ospemifene D4 | FC-1271a D4 | Estrogen/progestogen Receptor |
Ospemifene D4 is a deuterium labeled Ospemifene. Ospemifene is a selective and orally active modulator of estrogen receptor. |
Cat No. | Product Name | Synonyms | Targets |
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TN6730 | Epoxyazadiradione | NF-κB | |
Epoxyazadiradione is an extract from Neem (Azadirachta indica) plant and may induce mitochondrial apoptosis and inhibition of NF-kB in human cervical cancer cells. | |||
T3383 | Cimifugin | Cimitin | Others |
Cimifugin (Cimitin) inhibits NO production induced by lipopolysaccharide in macrophage cell line RAW 264.7 and for 1, 1-diphenyl-2-picrylhydrazyl free-radical scavenging activity in cell-free bioassay system. | |||
T3805 | Prim-O-glucosylcimifugin | Cimifugin beta-D-glucopyranoside,Cimifugin 7-glucoside | TNF , COX , JAK , NO Synthase |
Prim-O-glucosylcimifugin (Cimifugin 7-glucoside) can inhibit the proliferation of SMC(smooth muscle cell) stimulated by TNF-alpha, increase the proportion of G0/G1 phase. | |||
TN3812 | Dehydrovomifoliol | AChR | |
Dehydrovomifoliol could be a marker of Polish heather honey. Dehydrovomifoliol exhibits moderate acetylcholinesterase (AChE) inhibitory activities. Dehydrovomifoliol shows significant cytotoxic activities against three h... | |||
TN1496 | Cimifugin 4'-O-β-D-glucopyranoside | Cimifugin 4'-O-beta-D-glucopyranoside | Others |
Cimifugin 4'-O-beta-D-glucopyranoside is a natural product | |||
TN2095 | Pomiferin | NOS , NF-κB , PDE | |
Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has anti-inflammatory and neuroprotective activities. | |||
T8204 | Gummiferin | Others | |
Gummiferin is a natural product for research related to life sciences. The catalog number is T8204 and the CAS number is 33286-30-5. | |||
T83532 | (Rac)-Dehydrovomifoliol | PBI 344 | |
(Rac)-Dehydrovomifoliol (PBI 344), a bisnorsesquiterpene, is present in Euphorbia peplus [1]. | |||
TN5250 | Vomifoliol | VEGFR , NF-κB , HIF | |
Vomifoliol is most likely the immediate precursor of dehydrovomifoliol, because of the organism converted abscisic acid (ABA), to dehydrovomifoliol as the major metabolise, and a cell-free extract exhibits vomifoliol deh... |
Cat No. | Product Name | Species | Expression System |
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TMPY-05176 | AMH Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Anti-Mullerian hormone (AMH), a member of the TGF-beta superfamily, is produced by granulosa cells (GCs) of preantral and small antral follicles and plays a role in regulating the recruitment of primordial follicles and ... | |||
TMPY-01357 | S100A9 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
S100A9 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 14.6 kDa and the accession number is P06702. | |||
TMPY-01356 | S100A8 Protein, Human, Recombinant (His) | Human | Baculovirus Insect Cells |
S100A8 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 12.2 kDa and the accession number is P05109. | |||
TMPY-02342 | MIF Protein, Mouse, Recombinant | Mouse | E. coli |
MIF Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 12.5 kDa and the accession number is P34884. | |||
TMPY-02095 | MIF Protein, Human, Recombinant (His) | Human | HEK293 Cells |
MIF Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is P14174. | |||
TMPY-02145 | MIF Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
MIF Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 13.8 kDa and the accession number is P34884. | |||
TMPY-01330 | S100A9 Protein, Human, Recombinant | Human | E. coli |
S100A9 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 26 and 13 kDa and the accession number is P06702. | |||
TMPK-01257 | DDT Proten, Canine, Recombinant (His) | Canine | E. coli |
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum ... | |||
TMPK-00864 | DDT Protein, Human, Recombinant (His) | Human | E. coli |
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum ... | |||
TMPK-00722 | DDT Protein, Mouse, Recombinant (His) | Mouse | E. coli |
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum ... | |||
TMPK-01307 | DDT Protein, Cynomolgus, Recombinant (His) | Cynomolgus | E. coli |
D-dopachrome tautomerase (D-DT) is a newly described cytokine and a member of the macrophage migration inhibitory factor (MIF) protein superfamily.The D-DT protein also is present in most tissues and circulates in serum ... | |||
TMPJ-01037 | CXCR4 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
C-X-C chemokine receptor type 4 (CXCR4) is an alpha-chemokine receptor specific for stromal-derived-factor-1 (SDF-1 also called CXCL12), a molecule endowed with potent chemotactic activity for lymphocytes. This receptor ... |