Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer time and allow greater acetylcholine release to stimulate muscle at the end plate.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 36.00 | |
100 mg | In stock | $ 50.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 48.00 |
Description | Amifampridine (3,4-Diaminopyridine) is predominantly in the treatment of a number of rare muscle diseases. Amifampridine works by blocking potassium channel efflux in nerve terminals so that action potential duration is increased. Ca2+ channels can then be open for a longer time and allow greater acetylcholine release to stimulate muscle at the end plate. |
Synonyms | 3,4-Pyridinediamine, Pyridine-3,4-Diamine, 3,4-Diaminopyridine |
Molecular Weight | 109.13 |
Formula | C5H7N3 |
CAS No. | 54-96-6 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
H2O: 24 mg/mL
DMSO: 60 mg/mL (549.8 mM)
You can also refer to dose conversion for different animals. More
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Amifampridine 54-96-6 Others LEMS Oral Potassium Channel KcsA 3,4-Pyridinediamine voltage-gated potassium myasthenic syndrome inhibit Pyridine-3,4-Diamine Inhibitor neurological disease 3,4-Diaminopyridine neuromuscular junction inhibitor