keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF).
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 121.00 | |
5 mg | In stock | $ 233.00 | |
10 mg | In stock | $ 412.00 | |
25 mg | In stock | $ 686.00 | |
50 mg | In stock | $ 977.00 | |
100 mg | In stock | $ 1,320.00 |
Description | Nemifitide acetate(173240-15-8 free base) (INN 00835 acetate) is a synthetic pentapeptide antidepressant with a potential for rapid onset of action. It is a peptide analog of melanocyte-inhibiting factor (MIF). |
In vitro | In-vitro studies indicate that both nemifitide and its active metabolite (M1) bind at micromolar concentrations to several receptors including the 5-HT2A, 5-HT2C, melanocortin MC4, MC5 and bombesin[3]. |
In vivo | Nemifitide (0.3 mg/kg; IP; daily; for 14 days) significantly increases swimming in the FSL rats after just 5 days of treatment and has long-lasting effect[2]. Nemifitide (0.0125-15.0 mg/kg) significantly increases swimming in the FSL rats at both low (0.025-0.3 mg/kg) and high (3.0-15.0 mg/kg) doses but not at intermediate (0.4-2.4 mg/kg) doses[2]. |
Synonyms | INN 00835 acetate |
Molecular Weight | 754.85 |
Formula | C35H47FN10O8 |
CAS No. | TP1127L1 |
keep away from moisture
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 10 mM
You can also refer to dose conversion for different animals. More
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Nemifitide acetate(173240-15-8 free base) TP1127L1 GPCR/G Protein Neuroscience 5-HT Receptor Nemifitide acetate(173240 15 8 free base) INN 00835 acetate INN00835 Acetate Nemifitide acetate(173240158 free base) INN 00835 Acetate INN-00835 Acetate inhibitor inhibit