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Search Result

Search Results for " tgf-β-1 "

Targets

ALK Autophagy TGF-beta/Smad

33

Compounds

4

Natural Products

1779

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T1942 DMH-1 DMH1 ALK , Autophagy , TGF-beta/Smad
DMH-1 is a potent and selective BMP inhibitor.
T4283 SRI-011381 TGF-beta/Smad
SRI-011381, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T16708 R-268712 ALK , TGF-beta/Smad
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is also an orally active transforming growth factor-β type I receptor inhibitor.
T2273 ITD-1 TGF-beta/Smad
ITD-1 is a potent and highly selective TGFβ pathway inhibitor.
T5129 SRI-011381 hydrochloride SRI-011381 hydrochloride [1629138-41-5(free base)] TGF-beta/Smad
SRI-011381 hydrochloride, a new-type agonist of the TGF-beta signaling pathway, is utilized in the treatment of Alzheimer's disease.
T9010 IMM-H007 Others , AMPK
IMM-H007 is a novel lipid-lowering agent, increasing abca1 protein expression
T23127 PD-161570 PD 161570 EGFR , FGFR , PDGFR , Src
PD-161570 is a potent and ATP-competitive human FGF-1 receptor inhibitor with an IC50 of 39.9 nM and a Ki of 42 nM. PD-161570 also inhibits the PDGFR, EGFR and c-Src tyrosine kinases with IC50 values of 310 nM, 240 nM, a...
T6146 Dorsomorphin dihydrochloride BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride AMPK , Autophagy , TGF-beta/Smad
Dorsomorphin dihydrochloride (BML-275 2HCl) is a potent, selective and ATP-competitive AMPK inhibitor (Ki: 109 nM) and does not exhibit significant activity on structurally related kinases.
T7676 LSKL, Inhibitor of Thrombospondin TSP-1 acetate LSKL, Inhibitor of Thrombospondin TSP-1 TGF-beta/Smad
LSKL, Inhibitor of Thrombospondin TSP-1 acetate is activation of TGF-β .
T5125 LY3200882 TGF-beta/Smad
LY3200882 is a highly selective inhibitor of TGF-β receptor type 1 (TGFβRI).
T2386 Pirfenidone S-7701,AMR-69,S-7701,AMR69 CCR , TGF-beta/Smad
Pirfenidone (AMR69) is an inhibitor for TGF-β production and TGF-β stimulated collagen production. Pirfenidone inhibits fibroblast, epidermal, platelet-derived, and transforming beta-1 growth factors, thereby slowing tum...
T11190 EMT inhibitor-1 Wnt/beta-catenin
EMT inhibitor-1 is an inhibitor of Hippo, Wnt signaling and TGF- macrophages (TGF-) with antitumor activity.
T76858 Ascrinvacumab PF-03446962 ALK , TGF-beta/Smad
Ascrinvacumab (PF-03446962) is a highly humanized IgG2 monoclonal antibody against ALK-1. Ascrinvacumab has a Kd value of 7 nM for human ALK1. Ascrinvacumab has an inhibitory effect on TGF-β and can be used to study hepa...
T69687 SRI-35241
SRI-35241 is an inhibitor of Thrombospondin 1 activation of TGF-β.
T79543 J27644 HDAC
J27644 is a potent HDAC (histone deacetylase) inhibitor that mitigates TGF-β (transforming growth factor beta)-induced pulmonary fibrosis [1].
T24612 Pentachloropseudilin PClP
Pentachloropseudilin is a selective inhibitor of Myosin-1. In target cells, It acts by suppressing transforming growth factor-β activity by accelerating cell-surface type II TGF-β receptor turnover.
T76497 KRFK
KRFK, a peptide originating from TSP-1, activates TGF-β and facilitates TGF-β-mediated signaling pathways, independently of thrombospondin (TSP) receptors like CD47 and CD36. This property makes KRFK a potential research...
T77155 Dalutrafusp alfa
Dalutrafusp alfa (AGEN-1423; GS-1423) is a bifunctional antibody targeting CD73 and TGF-β, components of the immunosuppressive pathway [1].
T80562 Nisevokitug NIS-793 TGF-beta/Smad
Nisevokitug (NIS-793) is an IgG2λ human monoclonal antibody that targets TGF-β (TGFB1/TGFB2). It is produced in CHO-K1 cells [1].
T78544 KRFK TFA
KRFK TFA, a TSP-1-derived peptide, activates TGF-β and enhances its associated signaling pathways independently of thrombospondin (TSP) receptors like CD47 and CD36. This compound has potential applications in research o...
T77189 Sudubrilimab
Sudubrilimab (HS636), an Ig G1-kappa monoclonal antibody targeting PDL1, is engineered with a TGF-β1 receptor II ectodomain (TGFBR2-ECD) fused to its C-terminus. This design enables Sudubrilimab to simultaneously inhibit...
T61586 TGFβ-IN-2
TGFβ-IN-2 (Compound 9d) effectively inhibits the accumulation of total collagen induced by TGF-β in NRK-49F cells, with an IC 50 value of 4.31 μM. It also suppresses the in vitro protein expression of COL1A1, α-SMA, and ...
T83770 Klotho-derived Peptide 1 (56-87) (human) TFA KP1 (56-87)
Klotho-derived peptide 1 (KP1) (56-87), a peptide originating from the human Klotho protein, disrupts TGF-β signaling by binding to TGF-β receptor types 1 and 2 (TGFBR1 and TGFBR2; Kds = 1.41 and 14.6 µM, respectively). ...
T78790 J-1048
J-1048, an activin receptor-like kinase 5 (ALK5) inhibitor, effectively suppresses TAA-induced liver fibrosis in mice through specific inhibition of the TGF-β/Smad signaling pathway [1].
T61203 ALK5-IN-8
ALK5-IN-8 is a highly effective inhibitor of TGFβRI (ALK5). It hinders the phosphorylation of ALK5 on downstream signaling proteins (Smad2 or Smad3) by obstructing the interaction between TGFβRI and ligands. Consequently...
T78585 Pentabromopseudilin
Pentabromopseudilin (PBrP), a marine antibiotic derived from Pseudomonas bromoutilis and Alteromonas luteoviolaceus, demonstrates antimicrobial, antitumor, and phytotoxic properties. It acts as a reversible, allosteric i...
T10442 A 83-01 sodium salt ALK
A 83-01 sodium salt is a potent inhibitor of TGF-β type I receptor ALK5 kinase, ALK4 and ALK7, with IC 50 s of 12 nM, 45 nM and 7.5 nM against the ALK5, ALK4 and ALK7 induced transcription, respectively [1].
T78798 MY-673
MY-673, a colchicine binding site inhibitor (CBSI), impedes tubulin polymerization and disrupts the ERK signaling pathway, consequently modulating SMAD4 protein expression in the TGF-β/SMAD pathway. This compound effecti...
T26925 Butaprost Butaprostum,TR-4979,(R)-Butaprost
Butaprost is a chemical compound that functions as a selective agonist for the prostaglandin E receptor (EP2). It exhibits an EC50 of 33 nM and a Ki of 2.4 μM when interacting with the murine EP2 receptor. However, Butap...
T71884 ß-Carboline-1-carboxylic acid
β-Carboline-1-carboxylic acid is an alkaloid that has been found in P. quassioides and has diverse biological activities. It reduces LPS-induced increases in MCP-1, TNF-α, IL-6, and IL-1β levels in RAW 264.7 cells when u...
T74414 S-Allylmercaptocysteine
S-allylmercaptocysteine, an organic sulfur compound derived from garlic, possesses anti-inflammatory and anti-oxidative properties beneficial in treating various pulmonary diseases. It exerts its anti-cancer effects thro...
T35438 (5E)-7-Oxozeaenol
(5E)-7-Oxozeaenol is a resorcylic acid lactone that has been found in the fungus MSX 63935 and has enzyme inhibitory and anticancer activities.1,2 It inhibits TGF-β-activated kinase 1 (TAK-1; IC50 = 1.3 μM).1 (5E)-7-Oxoz...
T80588 Bintrafusp alfa M7824,MSB0011359C
Bintrafusp alfa (M 7824), a pioneering bifunctional fusion protein, integrates the extracellular domain of TGF-βRII with a human IgG1 monoclonal antibody that inhibits the programmed cell death ligand. This compound is u...

Compounds

DMH-1
T1942
Synonym: DMH1
Target: ALK, Autophagy, TGF-beta/Smad
SRI-011381
T4283
Synonym:
Target: TGF-beta/Smad
R-268712
T16708
Synonym:
Target: ALK, TGF-beta/Smad
ITD-1
T2273
Synonym:
Target: TGF-beta/Smad
SRI-011381 hydrochloride
T5129
Synonym: SRI-011381 hydrochloride [1629138-41-5(free base)]
Target: TGF-beta/Smad
IMM-H007
T9010
Synonym:
Target: Others, AMPK
PD-161570
T23127
Synonym: PD 161570
Target: EGFR, FGFR, PDGFR, Src
Dorsomorphin dihydrochloride
T6146
Synonym: BML-275 2HCl,Compound C dihydrochloride,Dorsomorphin (Compound C) 2HCl,Compound C 2HCl,BML-275 dihydrochloride
Target: AMPK, Autophagy, TGF-beta/Smad
LSKL, Inhibitor of Thrombospondin TSP-1 acetate
T7676
Synonym: LSKL, Inhibitor of Thrombospondin TSP-1
Target: TGF-beta/Smad
LY3200882
T5125
Synonym:
Target: TGF-beta/Smad
Pirfenidone
T2386
Synonym: S-7701,AMR-69,S-7701,AMR69
Target: CCR, TGF-beta/Smad
EMT inhibitor-1
T11190
Synonym:
Target: Wnt/beta-catenin
Ascrinvacumab
T76858
Synonym: PF-03446962
Target: ALK, TGF-beta/Smad
SRI-35241
T69687
Synonym:
Target:
J27644
T79543
Synonym:
Target: HDAC
Pentachloropseudilin
T24612
Synonym: PClP
Target:
KRFK
T76497
Synonym:
Target:
Dalutrafusp alfa
T77155
Synonym:
Target:
Nisevokitug
T80562
Synonym: NIS-793
Target: TGF-beta/Smad
KRFK TFA
T78544
Synonym:
Target:
Sudubrilimab
T77189
Synonym:
Target:
TGFβ-IN-2
T61586
Synonym:
Target:
Klotho-derived Peptide 1 (56-87) (human) TFA
T83770
Synonym: KP1 (56-87)
Target:
J-1048
T78790
Synonym:
Target:
ALK5-IN-8
T61203
Synonym:
Target:
Pentabromopseudilin
T78585
Synonym:
Target:
A 83-01 sodium salt
T10442
Synonym:
Target: ALK
MY-673
T78798
Synonym:
Target:
Butaprost
T26925
Synonym: Butaprostum,TR-4979,(R)-Butaprost
Target:
ß-Carboline-1-carboxylic acid
T71884
Synonym:
Target:
S-Allylmercaptocysteine
T74414
Synonym:
Target:
(5E)-7-Oxozeaenol
T35438
Synonym:
Target:
Bintrafusp alfa
T80588
Synonym: M7824,MSB0011359C
Target:
Cat No. Product Name Synonyms Targets
T6856 Halofuginone Tempostatin,empostatin,RU-19110 Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone (RU-19110), the competitive inhibitor of prolyl-tRNA synthetase(Ki=18.3 nM), could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in the mammal.
T3524 Halofuginone hydrobromide Tempostatin,RU-19110 (hydrobromide),Stenorol Others , Calcium Channel , DNA/RNA Synthesis , Sodium Channel , Parasite , TGF-beta/Smad
Halofuginone specifically inhibits collagen type I gene expression and matrix metalloproteinase 2 (MMP-2) gene expression, which may result in the suppression of angiogenesis, tumor stromal cell development, and tumor ce...
T75526 Chlorfortunone A
Chlorfortunone A, a novel sesquiterpenoid dimer isolated from the roots of Chloranthus fortunei, inhibits transforming growth factor (TGF)-β activity [1].
T14055 5Z-7-Oxozeaenol FR148083,L783279,LL-Z 1640-2 VEGFR , FLT , MEK , MAPK , PDGFR , Antibiotic , Src
5Z-7-Oxozeaenol (FR148083) is a potent, irreversible and selective inhibitor of transforming growth factor (TGF)-β-activated kinase 1 with IC50 of 8.1 nM for TAK1 and low activity against MEK1 with IC50 of 411 nM, it is ...

Natural Products

Halofuginone
T6856
Synonym: Tempostatin,empostatin,RU-19110
Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Halofuginone hydrobromide
T3524
Synonym: Tempostatin,RU-19110 (hydrobromide),Stenorol
Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad
Chlorfortunone A
T75526
Synonym:
Target:
5Z-7-Oxozeaenol
T14055
Synonym: FR148083,L783279,LL-Z 1640-2
Target: VEGFR, FLT, MEK, MAPK, PDGFR, Antibiotic, Src

Recombinant Proteins

Species：
Human (1439)
Mouse (239)
Cynomolgus (30)
Rat (28)
Chinese hamster (4)
Mouse,Rat (4)
RSV (4)
Canine (3)
Phleum pratense (3)
Human (2)
Expression System：
HEK293 (1339)
E. coli (210)
Baculovirus-Insect Cells (185)
Human Cells (19)
CHO (15)
Yeast (11)
Tag：
His (712)
hFc (232)
C-His-Avi (181)
Tag Free (109)
C-His (95)
His,GST (73)
C-hFc (54)
mFc (40)
His,AVI (39)
GST (38)
Cat No. Product Name Species Expression System
TMPK-01243 GDF-15 Protein, Rat, Recombinant (His) Rat E. coli
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GD...
TMPK-01246 GDF-15 Protein, Mouse, Recombinant (His) Mouse E. coli
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPJ-00249 TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated Human Human Cells
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPK-00305 TGFBR1 Protein, Human, Recombinant (mFc & Avi) Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-06247 TGF beta 3 Protein, Human, Recombinant (hFc) Human HEK293
TGF beta 3 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 41.2 kDa. Accession number: P10600-1
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-00261 TGF beta 2 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofaci...
TMPJ-00258 TGF beta 2 Protein, Human, Recombinant Human Human Cells
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. T...
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant Human,Rhesus,Cynomolgus,Canine CHO
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His) Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant Mouse,Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-00771 TGF beta 1 Protein, Mouse/Rat, Recombinant Mouse,Rat Human Cells
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differen...
TMPK-00196 GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GD...
TMPK-00197 GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated Human HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-01244 GDF-15 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00569 GDF-15 Protein, Canine, Recombinant (His) Canine E. coli
Growth Differentiation Factor 15 (GDF15), also known as NSAID activated gene-1 (NAG-1), is associated with a large number of biological processes and diseases, including cancer and obesity. GDF15 is synthesized as pro-GD...
TMPK-00665 GDF-15 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00664 GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated Cynomolgus HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00198 GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated Human HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-01245 GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated Mouse HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00663 GDF-15 Protein, Cynomolgus, Recombinant (hFc) Cynomolgus HEK293
Growth and differentiation factor 15 (GDF15) is an inflammation-associated hormone with poorly defined biology. Here, we investigated the role of GDF15 in bacterial and viral infections. Inflammation induced GDF15, and t...
TMPK-00306 TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated Human HEK293
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the sup...
TMPY-05521 Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-00250 LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated Human Human Cells
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activ...
TMPY-05313 Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-01178 TGFBR1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Pho...
TMPJ-00622 Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPY-00229 Latent TGF beta 1 Protein, Canine, Recombinant (His) Canine HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPJ-00772 Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated Mouse Human Cells
Transforming growth factor beta (TGFβ) is a multifunctional cytokine that regulates cell growth, differentiation, adhesion, migration and death dependent on cell type, developmental stage, or tissue conditions. There are...
TMPJ-00254 TGF beta 3 Protein, Human/Mouse/Rat, Recombinant Human,Mouse,Rat Human Cells
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes acti...
TMPY-01384 Endoglin/CD105 Protein, Human, Recombinant (His) Human HEK293
Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPY-04727 GDF-15 Protein, Human, Recombinant (His) Human Yeast
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not...
TMPY-01073 GDF-15 Protein, Human, Recombinant (hFc) Human HEK293
Growth-differentiation factor 15 (GDF15), also known as MIC-1, is a secreted member of the transforming growth factor (TGF)-β superfamily, as a novel antihypertrophic regulatory factor in the heart. GDF-15 / GDF15 is not...
TMPK-00744 LRP-6 Protein, Human, Recombinant (mFc) Human HEK293
Dickkopf-related protein 1 (DKK-1), a ligand for the WNT coreceptors low-density lipoprotein receptor-related proteins 5 and 6 (LRP-5 and LRP-6) and an inhibitor of WNT/β-catenin signaling, effectively inhibits pericyte ...
TMPY-03058 SLITL2/VASN Protein, Human, Recombinant (His) Human HEK293
Vasorin is a typical type I membrane protein. It contains 1 EGF-like domain, 1 fibronectin type-III domain, 10 LRR (leucine-rich) repeats, 1 LRRCT domain and 1 LRRNT domain. Vasorin is predominantly expressed in vascular...
TMPY-01615 Endoglin/CD105 Protein, Mouse, Recombinant (His) Mouse HEK293
Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPY-00783 Endoglin/CD105 Protein, Human, Recombinant (hFc) Human HEK293
Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPJ-01473 BMP-7 Protein, Human, Recombinant Human Human Cells
Bone morphogenetic protein 7 (BMP7), also known as osteogenic protein-1 (OP-1) is a member of Transforming growth factor-β (TGF-β) family of proteins. Bone morphogenetic proteins were discovered in 1965 by Marshal Urist,...
TMPY-00486 ALK-7 Protein, Human, Recombinant (hFc) Human HEK293
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 ...
TMPJ-00100 Artemin Protein, Human, Recombinant Human E. coli
Human Artemin is a GDNF family ligand that is distantly related to the TGF-β superfamily of molecules. It is synthesized as a preproprotein, and contains a variable length pre-, or signal sequence, plus a 68 amino acid (...
TMPJ-00304 ALK-1 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Activin Receptor-Like Kinase 1 (ALK-1) is a type I cell-surface receptor for the TGF-β superfamily of ligands, which mediates signaling of BMP9 (bone morphogenetic protein) and BMP10. ALK1 signaling is necessary for angi...
TMPY-03187 ALK-7 Protein, Rhesus, Recombinant (hFc) Rhesus HEK293
ALK-7, also known as ALK7 and ACVR1C, belongs to the ALK family. It is a type I receptor for the TGFB family of signaling molecules. TGF-β is the prototype of a protein superfamily which, in humans, contains at least 35 ...
TMPY-01994 GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (His) Rat HEK293
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a...
TMPJ-01290 Neurturin Protein, Human, Recombinant Human E. coli
Neurturin is a member of the GDNF family of ligands, which include glial cell-derived neurotrophic factor (GDNF), Neurturin, Persephin, and Artemin. Neurturin is expressed in both neuronal and nonneuronal tissues. Simila...
TMPY-01027 Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His) Mouse HEK293
Mast Cell Protease 1 (MMCP-1), also known as MCP-1, MCPT-1 and β-chymase, is a member of the Chymase family of chymotrypsin-like serine proteases. MCPT-1 is a 26 kDa β-chymase that is a component of mast cell granules. I...
TMPY-05490 GFR Alpha-1/GFRA1 Protein, Human, Recombinant (hFc) Human HEK293
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a...
TMPY-03709 GFR Alpha-1/GFRA1 Protein, Canine, Recombinant (His) Canine HEK293
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a...
TMPY-01419 GFR Alpha-1/GFRA1 Protein, Human, Recombinant (His) Human HEK293
Glial cell line derived neurotrophic factor (GDNF) Family Receptor Alpha 1 (GFRA1) is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, a...
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GDF-15 Protein, Rat, Recombinant (His)
TMPK-01243
Species: Rat
Expression System: E. coli
GDF-15 Protein, Mouse, Recombinant (His)
TMPK-01246
Species: Mouse
Expression System: E. coli
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TMPJ-00249
Species: Human
Expression System: Human Cells
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
TMPK-00305
Species: Human
Expression System: HEK293
TGF beta 3 Protein, Human, Recombinant (hFc)
TMPY-06247
Species: Human
Expression System: HEK293
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
TMPY-00500
Species: Mouse
Expression System: HEK293
TGF beta 2 Protein, Mouse/Rat, Recombinant
TMPJ-00261
Species: Mouse,Rat
Expression System: Human Cells
TGF beta 2 Protein, Human, Recombinant
TMPJ-00258
Species: Human
Expression System: Human Cells
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO
Latent TGF beta 1 Protein, Rat, Recombinant (His)
TMPY-03945
Species: Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
TMPY-04211
Species: Cynomolgus
Expression System: HEK293
TGF beta 1 Protein, Rat/Mouse, Recombinant
TMPY-00608
Species: Mouse,Rat
Expression System: HEK293
TGF beta 1 Protein, Mouse/Rat, Recombinant
TMPJ-00771
Species: Mouse,Rat
Expression System: Human Cells
GDF-15 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00196
Species: Human
Expression System: E. coli
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (H202D, hFc), Biotinylated
TMPK-00197
Species: Human
Expression System: HEK293
GDF-15 Protein, Mouse, Recombinant (hFc)
TMPK-01244
Species: Mouse
Expression System: HEK293
GDF-15 Protein, Canine, Recombinant (His)
TMPK-00569
Species: Canine
Expression System: E. coli
GDF-15 Protein, Cynomolgus, Recombinant (His)
TMPK-00665
Species: Cynomolgus
Expression System: E. coli
GDF-15 Protein (Primary Amine Labeling), Cynomolgus, Recombinant (hFc), Biotinylated
TMPK-00664
Species: Cynomolgus
Expression System: HEK293
GDF-15 Protein (Primary Amine Labeling), Human, Recombinant (hFc), Biotinylated
TMPK-00198
Species: Human
Expression System: HEK293
GDF-15 Protein (Primary Amine Labeling), Mouse, Recombinant (hFc), Biotinylated
TMPK-01245
Species: Mouse
Expression System: HEK293
GDF-15 Protein, Cynomolgus, Recombinant (hFc)
TMPK-00663
Species: Cynomolgus
Expression System: HEK293
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TMPK-00306
Species: Human
Expression System: HEK293
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
TMPY-05521
Species: Human
Expression System: HEK293
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00250
Species: Human
Expression System: Human Cells
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05313
Species: Mouse
Expression System: HEK293
TGFBR1 Protein, Mouse, Recombinant (hFc)
TMPJ-01178
Species: Mouse
Expression System: Human Cells
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
TMPJ-00622
Species: Cynomolgus
Expression System: Human Cells
Latent TGF beta 1 Protein, Canine, Recombinant (His)
TMPY-00229
Species: Canine
Expression System: HEK293
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
TMPJ-00772
Species: Mouse
Expression System: Human Cells
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
TMPJ-00254
Species: Human,Mouse,Rat
Expression System: Human Cells
Endoglin/CD105 Protein, Human, Recombinant (His)
TMPY-01384
Species: Human
Expression System: HEK293
GDF-15 Protein, Human, Recombinant (His)
TMPY-04727
Species: Human
Expression System: Yeast
GDF-15 Protein, Human, Recombinant (hFc)
TMPY-01073
Species: Human
Expression System: HEK293
LRP-6 Protein, Human, Recombinant (mFc)
TMPK-00744
Species: Human
Expression System: HEK293
SLITL2/VASN Protein, Human, Recombinant (His)
TMPY-03058
Species: Human
Expression System: HEK293
Endoglin/CD105 Protein, Mouse, Recombinant (His)
TMPY-01615
Species: Mouse
Expression System: HEK293
Endoglin/CD105 Protein, Human, Recombinant (hFc)
TMPY-00783
Species: Human
Expression System: HEK293
BMP-7 Protein, Human, Recombinant
TMPJ-01473
Species: Human
Expression System: Human Cells
ALK-7 Protein, Human, Recombinant (hFc)
TMPY-00486
Species: Human
Expression System: HEK293
Artemin Protein, Human, Recombinant
TMPJ-00100
Species: Human
Expression System: E. coli
ALK-1 Protein, Mouse, Recombinant (hFc)
TMPJ-00304
Species: Mouse
Expression System: Human Cells
ALK-7 Protein, Rhesus, Recombinant (hFc)
TMPY-03187
Species: Rhesus
Expression System: HEK293
GFR Alpha-1/GFRA1 Protein, Rat, Recombinant (His)
TMPY-01994
Species: Rat
Expression System: HEK293
Neurturin Protein, Human, Recombinant
TMPJ-01290
Species: Human
Expression System: E. coli
Mast Cell Protease-1/MCPT-1 Protein, Mouse, Recombinant (His)
TMPY-01027
Species: Mouse
Expression System: HEK293
GFR Alpha-1/GFRA1 Protein, Human, Recombinant (hFc)
TMPY-05490
Species: Human
Expression System: HEK293
GFR Alpha-1/GFRA1 Protein, Canine, Recombinant (His)
TMPY-03709
Species: Canine
Expression System: HEK293
GFR Alpha-1/GFRA1 Protein, Human, Recombinant (His)
TMPY-01419
Species: Human
Expression System: HEK293
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