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Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
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Search Result

Search Results for " ly-a "

Targets

Others Phospholipase

150

Compounds

1

Natural Products

148

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T17218 Varespladib methyl A-002,LY333013 Others , Phospholipase
Varespladib methyl (LY333013), a bioavailable prodrug of Varespladib, is a selective group II secretory phospholipase A2 inhibitor.
T8875 CD73-IN-3 EX-A4254,LY-3475070 CD73
CD73-IN-3 (LY-3475070) is a potent and selective CD73 inhibitor with an IC50 of 28 nM, and its use alone or in combination with pembrolizumab is currently being tested in patients with advanced cancer.
T9078 LY3405105 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester CDK
LY3405105 (1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester) is a novel CDK7 inhibitors.
T22948 LY 272015 hydrochloride Others
LY 272015 hydrochloride is a 5-HT2B receptor antagonist.
T2344L LY 344864 racemate 5-HT Receptor
LY 344864 racemate is a 5-HT1F receptor agonist.
T19638 LY-301664 LY301664,LY 301664 Others
LY-301664 is a compound which has bio-active.
T27954 LY-402913 LY 402913,LY402913 MRP
LY-402913 is a selective multidrug resistance protein (MRP1) inhibitor.
T4423 LY 303511 hydrochloride LY303511 hydrochloride Potassium Channel , TNF , mTOR
LY 303511 hydrochloride is a potent mTOR inhibitor
T2344 LY 344864 LY344864 5-HT Receptor
LY 344864, a specifc receptor agonist, is an affinity of 6 nM (Ki) at the recently cloned 5-HT1F receptor.
T2048 LY-364947 LY 364947,HTS466284 MLK , Casein Kinase , TGF-beta/Smad , RIP kinase
LY-364947 (HTS466284) is a potent ATP-competitive inhibitor of TGFβR-I.
T22956 LY 78335 1-(2,3-Dichlorophenyl)ethanamine hydrochloride Others
LY 78335 (1-(2,3-Dichlorophenyl)ethanamine hydrochloride) is a phenylethanolamine-N-methyltransferase (PNMT) inhibitor.
T24421 LY-2624803 DB-7,LY2624803,HY-10275,LY 2624803 5-HT Receptor , Histamine Receptor
LY-2624803 is a 5-HT2A receptor antagonist and histamine receptor inverse agonist that can be used to improve slow wave sleep.
TQ0082 Aticaprant LY-2456302,CERC-501 Opioid Receptor
Aticaprant (LY-2456302) (CERC-501) is a potent and centrally-penetrant antagonist of the kappa-opioid receptor (Ki: 0.807 nM).
T6018 Zosuquidar trihydrochloride Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride P-gp
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3.
T22437 Tazofelone LY-213829 Others
Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.
T6461 Dapoxetine hydrochloride LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy 5-HT Receptor , Serotonin Transporter
Dapoxetine hydrochloride (LY-210448 hydrochloride) is a selectivity short-acting serotonin reuptake inhibitor, used for the therapy of premature ejaculation.
T1746 LY-2584702 tosylate salt LY2584702 tosylate S6 Kinase
LY-2584702 tosylate salt is a selective, ATP-competitive p70S6K inhibitor, used in trials studying the treatment of cancer.
TQ0116 LY 3000328 Cathepsin S inhibitor Cysteine Protease
LY 3000328 (Cathepsin S inhibitor) is a potent, highly selective Cathepsin S (Cat S) inhibitor (IC50s: 7.7 and 1.67 nM for hCat S and mCat S).
T0450 Fluoxetine LY-110140 5-HT Receptor , Serotonin Transporter , MRP , Autophagy
Fluoxetine (LY-110140) is a highly specific serotonin uptake inhibitor and selective 5-hydroxytryptamine (5-HT) reuptake inhibitor. Fluoxetine has antidepressant activity.
T68127 Picenadol LY-150720,LY150720,LY 150720 Others
Picenadol (LY 150720) is a racemic mixture of N-methyl-4-phenylpiperidine derivatives with agonist-antagonist opioid properties.Picenadol has central analgesic activity.
T15827 LY 345899 DHFR
LY 345899 is a Folate analog and is a methylenetetrahydrofolate dehydrogenase and MTHFD2 inhibitor (IC50: 96 nM and 663 nM, respectively and a Ki: 18 nM for MTHFD1).
T0189 Pemetrexed Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
Pemetrexed (LY-231514 Disodium Hydrate), a guanine-derived antineoplastic agent, binds to and inhibits the enzyme thymidylate synthase (TS).
T6069 Gemcitabine hydrochloride Gemcitabine HCl,Gemzar,LY188011,LY 188011 hydrochloride Apoptosis , Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Autophagy
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy a...
T6063 LY-411575 LY411575 Apoptosis , Gamma-secretase
LY-411575, a potent γ-secretase inhibitor, is with IC50 of 0.078 nM in the membrane and 0.082 nM in cell-based. It also suppresses Notch clevage with IC50 of 0.39 nM.
T29421 LY195448 4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide Others
LY 195448 (4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide) is a substance present in human blood and urine that shows antitumor activity in a mouse tumor model and blocks cells in the mid-stage.
T4079 LY-294002 hydrochloride SF 1101,LY 294002,NSC 697286 PI3K
LY-294002 hydrochloride (NSC 697286) is a synthetic molecule inhibitor of PI3Kα/δ/β (IC50: 0.5/0.57/0.97 μM, in cell-free assays); more stable than Wortmannin in solution, and also is a blocker of autophagosome formation...
T6202 DAPT LY-374973,GSI-IX Apoptosis , Beta Amyloid , Gamma-secretase , Autophagy
DAPT (LY-374973) is a γ-secretase inhibitor that inhibits total Aβ and Aβ42 (IC50=115/200 nM) and is orally active. DAPT is also a Notch inhibitor. DAPT induces cell differentiation, autophagy and apoptosis.
T26619 Amitivir LY217896,LY 217896,LY-217896 Others , Influenza Virus
Amitivir (LY 217896) is an inosine monophosphate dehydrogenase inhibitor. Amitivir inhibits the replication of dividing MDCK cells. Amitivir was associated with asymptomatic rises in serum uric acid levels and was ineffe...
T6952 Prasugrel Hydrochloride LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl P2Y Receptor
Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.
TP1111 Tirzepatide LY-3298176 Glucagon Receptor
Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity.
T6226 Pemetrexed disodium hemipenta hydrate Pemetrexed Disodium Hydrate,LY-231514 Disodium Hydrate,Pemetrexed sodium hydrate Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
Pemetrexed disodium hemipenta hydrate (LY-231514 Disodium Hydrate) is a new-type antifolate and antimetabolite for TS, DHFR, and GARFT. The Ki of Pemetrexed Disodium Hydrate for TS, DHFR and GARFT is 1.3 nM, 7.2 nM and 6...
T3689 Ruboxistaurin hydrochloride Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride PKC
Ruboxistaurin hydrochloride (LY 333531 hydrochloride) is an Isozyme-selective inhibitor of protein kinase C (PKC); competitively and reversibly inhibits PKCβI and PKCβII (IC50 values are 4.7 and 5.9 nM respectively). Sel...
T0189L Pemetrexed disodium LY-231514,LY231514 disodium,Pemetrexed Apoptosis , DHFR , DNA/RNA Synthesis , Antifolate , Autophagy
Pemetrexed disodium (LY-231514) is a parenterally administered folate antagonist and antineoplastic agent, used in the treatment of non-small cell lung cancer and malignant mesothelioma. Pemetrexed disodium therapy has b...
T36640 Xanomeline LY-246708 AChR
Xanomeline (LY-246708) is a functionally selective M1/M4 activator used in the study of neurological disorders such as schizophrenia and has shown promising treatment in preclinical trials. Xanomeline is well absorbed or...
T1242 Alvimopan Opioid Receptor
Alvimopan (LY 246736) is a synthetic trans-3, 4-dimethyl-4-(3-hydroxyphenyl) piperidine with peripherally selective opioid mu receptor antagonist activity. Alvimopan is a selective and competitive antagonist at mu-opioid...
T0869 Atomoxetine hydrochloride Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,LY 139603,Atomoxetine HCl,LY 139603 HCl Dopamine Receptor , 5-HT Receptor , Norepinephrine
Atomoxetine hydrochloride (LY 139603) is the hydrochloride salt of atomoxetine, a phenoxy-3-propylamine derivative and selective non-stimulant, norepinephrine reuptake inhibitor with cognitive-enhancing activity. Althou...
T15826 Lometrexol LY 264618,DDATHF DHFR
Lometrexol (LY 264618), an antipurine Antifolate, can inhibit the activity of glycinamide ribonucleotide formyltransferase (GARFT) but do not induce detectable levels of DNA strand breaks. Lometrexol can further inhibit ...
T6159 LY-2584702 free base S6 Kinase , mTOR
LY2584702 is a selective, ATP-competitive p70S6K inhibitor(IC50: 4 nM).
T32991 LY 175877 LY175877,LY-175877
LY 175877 is a bioactive chemical.
T27869 LY 116467 LY-116467,LY116467
LY 116467 is a dopamine agonist.
T27871 LY 125180 LY125180,LY-125180
LY 125180 is a serotonin antagonist.
T33008 LY-228729
LY-228729 is a bioactive chemical.
T33002 LY 295427
LY 295427 is a bioactive chemical.
T33009 LY-290411
LY-290411 is a bioactive chemical.
T33001 LY 294619
LY 294619 is a bioactive hcemical.
T33000 LY 294486
LY 294486 is a bioactive chemical.
T33014 LY-368842
LY-368842 is a bioactive chemical.
T32999 LY 289612
LY 289612 is a bioactive chemical.
T32995 LY 227942
LY 227942 is a bioactive chemical.
T27873 LY 135114 LY135114,LY-135114
LY 135114 is a metabolite of LY 195448, which is a phenethanolamine with anti-tumour activity.

Compounds

Varespladib methyl
T17218
Synonym: A-002,LY333013
Target: Others, Phospholipase
CD73-IN-3
T8875
Synonym: EX-A4254,LY-3475070
Target: CD73
LY3405105
T9078
Synonym: 1-Piperidinecarboxylic acid, 4-[[5-methyl-3-(1-methylethyl)pyrazolo[1,5-a]pyrimidin-7-yl]amino]-, 1-[(2E)-4-(dimethylamino)-1-oxo-2-buten-1-yl]-3-pyrrolidinyl ester
Target: CDK
LY 272015 hydrochloride
T22948
Synonym:
Target: Others
LY 344864 racemate
T2344L
Synonym:
Target: 5-HT Receptor
LY-301664
T19638
Synonym: LY301664,LY 301664
Target: Others
LY-402913
T27954
Synonym: LY 402913,LY402913
Target: MRP
LY 303511 hydrochloride
T4423
Synonym: LY303511 hydrochloride
Target: Potassium Channel, TNF, mTOR
LY 344864
T2344
Synonym: LY344864
Target: 5-HT Receptor
LY-364947
T2048
Synonym: LY 364947,HTS466284
Target: MLK, Casein Kinase, TGF-beta/Smad, RIP kinase
LY 78335
T22956
Synonym: 1-(2,3-Dichlorophenyl)ethanamine hydrochloride
Target: Others
LY-2624803
T24421
Synonym: DB-7,LY2624803,HY-10275,LY 2624803
Target: 5-HT Receptor, Histamine Receptor
Aticaprant
TQ0082
Synonym: LY-2456302,CERC-501
Target: Opioid Receptor
Zosuquidar trihydrochloride
T6018
Synonym: Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride
Target: P-gp
Tazofelone
T22437
Synonym: LY-213829
Target: Others
Dapoxetine hydrochloride
T6461
Synonym: LY-210448,LY-210448 hydrochloride,Dapoxetine HCl,Priligy
Target: 5-HT Receptor, Serotonin Transporter
LY-2584702 tosylate salt
T1746
Synonym: LY2584702 tosylate
Target: S6 Kinase
LY 3000328
TQ0116
Synonym: Cathepsin S inhibitor
Target: Cysteine Protease
Fluoxetine
T0450
Synonym: LY-110140
Target: 5-HT Receptor, Serotonin Transporter, MRP, Autophagy
Picenadol
T68127
Synonym: LY-150720,LY150720,LY 150720
Target: Others
LY 345899
T15827
Synonym:
Target: DHFR
Pemetrexed
T0189
Synonym: Pemetrexed acid,LY231514,LY-231514 Disodium Hydrate
Target: DHFR, DNA/RNA Synthesis, Antifolate, Autophagy
Gemcitabine hydrochloride
T6069
Synonym: Gemcitabine HCl,Gemzar,LY188011,LY 188011 hydrochloride
Target: Apoptosis, Nucleoside Antimetabolite/Analog, DNA/RNA Synthesis, Autophagy
LY-411575
T6063
Synonym: LY411575
Target: Apoptosis, Gamma-secretase
LY195448
T29421
Synonym: 4-(3-(2-Hydroxy-2-phenyl)ethylamino-3-methylbutyl)benzamide
Target: Others
LY-294002 hydrochloride
T4079
Synonym: SF 1101,LY 294002,NSC 697286
Target: PI3K
DAPT
T6202
Synonym: LY-374973,GSI-IX
Target: Apoptosis, Beta Amyloid, Gamma-secretase, Autophagy
Amitivir
T26619
Synonym: LY217896,LY 217896,LY-217896
Target: Others, Influenza Virus
Prasugrel Hydrochloride
T6952
Synonym: LY 640315,PCR 4099 (hydrochloride),Effient Hydrochloride,LY 640315 Hydrochloride,Prasugrel HCl
Target: P2Y Receptor
Tirzepatide
TP1111
Synonym: LY-3298176
Target: Glucagon Receptor
Pemetrexed disodium hemipenta hydrate
T6226
Synonym: Pemetrexed Disodium Hydrate,LY-231514 Disodium Hydrate,Pemetrexed sodium hydrate
Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy
Ruboxistaurin hydrochloride
T3689
Synonym: Ruboxistaurin,LY333531 HCl,LY 333531 hydrochloride
Target: PKC
Pemetrexed disodium
T0189L
Synonym: LY-231514,LY231514 disodium,Pemetrexed
Target: Apoptosis, DHFR, DNA/RNA Synthesis, Antifolate, Autophagy
Xanomeline
T36640
Synonym: LY-246708
Target: AChR
Alvimopan
T1242
Synonym:
Target: Opioid Receptor
Atomoxetine hydrochloride
T0869
Synonym: Tomoxetine hydrochloride,(R)-Tomoxetine hydrochloride,LY 139603,Atomoxetine HCl,LY 139603 HCl
Target: Dopamine Receptor, 5-HT Receptor, Norepinephrine
Lometrexol
T15826
Synonym: LY 264618,DDATHF
Target: DHFR
LY-2584702 free base
T6159
Synonym:
Target: S6 Kinase, mTOR
LY 175877
T32991
Synonym: LY175877,LY-175877
Target:
LY 116467
T27869
Synonym: LY-116467,LY116467
Target:
LY 125180
T27871
Synonym: LY125180,LY-125180
Target:
LY-228729
T33008
Synonym:
Target:
LY 295427
T33002
Synonym:
Target:
LY-290411
T33009
Synonym:
Target:
LY 294619
T33001
Synonym:
Target:
LY 294486
T33000
Synonym:
Target:
LY-368842
T33014
Synonym:
Target:
LY 289612
T32999
Synonym:
Target:
LY 227942
T32995
Synonym:
Target:
LY 135114
T27873
Synonym: LY135114,LY-135114
Target:
1 2 3
Cat No. Product Name Synonyms Targets
T75635 Microcystin-LY
Microcystin-LY, a cyclic heptapeptide toxin produced by the cyanobacterium Microcystis aeruginosa [2], functions as a potent activator of the Nrf2 pathway, thereby inducing an oxidative stress response. Its activation ef...

Natural Products

Microcystin-LY
T75635
Synonym:
Target:

Recombinant Proteins

Species：
Human (137)
Mouse (7)
Human & Mouse (4)
Expression System：
HEK293 Cells (131)
E. coli (17)
Tag：
C-His-Avi (138)
C-His (4)
N-His (3)
C-hFc (2)
N-His-Avi (1)
Cat No. Product Name Species Expression System
TMPY-01334 CD5 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CD5 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is P13379.
TMPY-05544 LY6A Protein, Mouse, Recombinant (His) Mouse E. coli
LY6A Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 10.9 kDa and the accession number is P05533.
TMPY-02414 Klrb1a Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Klrb1a Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21 kDa and the accession number is P27811.
TMPY-01206 CD86 Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
CD86 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.8 kDa and the accession number is P42082-1.
TMPY-05386 CD86 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
CD86 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52 kDa and the accession number is P42082-1.
TMPY-05133 CD86 Protein, Mouse, Recombinant (His), Biotinylated Mouse HEK293 Cells
CD86 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.7 kDa and the accession number is P42082-1.
TMPY-03999 MD2/LY96 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
LY96 (Lymphocyte Antigen 96, also known as ESOP-1) is a Protein Coding gene. 2 alternatively spliced human isoforms have been reported. This gene encodes a protein that associates with toll-like receptor 4 on the cell su...
TMPY-02440 SAP/SH2D1A Protein, Human, Recombinant (His) Human E. coli
SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of...
TMPK-01422 Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01415 APC-equivalent Peptide Ready HLA-A*02:01&B2M Tetramer Protein, Human, MHC (His) Human HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Tetramer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M...
TMPK-01421 Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
HLA-A*02:01&B2M&Peptide ready Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*02:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01419 Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Peptide Ready HLA-A*03:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*03:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01425 Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01426 Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-A*11:01. Peptide ready MHC molecules comprising human HLA alleles and B2M,...
TMPK-01409 Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Peptide Ready HLA-G&B2M Monomer is absent from peptide, namely peptide-receptive MHC. It can be loaded with antigenic peptides matching HLA-G. Peptide ready MHC molecules comprising human HLA alleles and B2M, which can b...
TMPK-01455 HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01406 HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled Human HEK293 Cells
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01432 HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01445 HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
MAGE-A1 belongs to the chromosome X-clustered genes of cancer-testis antigen family and is normally expressed in the human germ line but is also overexpressed in various tumors.
TMPK-01468 HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Melanoma antigen recognized by T cell-1 (Mart-1), one of the melanosome-specific proteins, also recognized by cytotoxicity T lymphocytes as a marker. Mart-1 is considered to play a critical role in the immunotherapy for ...
TMPK-01459 HLA-A*02:01&B2M&MAGE-A4 or MAGE-A8 (KVLEHVVRV) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
MAGE-A4 and MAGE-A8 are type I membes of the melanoma associated antigen (MAGE) family. The MAGE family is a large, highly conserved group of proteins that share a common MAGE homology domain. Both MAGE-A4 and MAGE-A8 an...
TMPK-01495 HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Melanoma antigen gene A3 (MAGE-A3) is one of the most immunogenic cancer testis antigens and is common in various types of cancers. MAGE-A3 can be considered as a predictor for poor prognosis and an option for vaccine im...
TMPK-01433 HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01482 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01496 HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Cancer/testis antigens 83 (CT83), also called KK-LC-1 or CXorf61, recognized by cytotoxic T lymphocytes (CTL), has become a promising target for immunotherapy.
TMPK-01530 HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01519 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01532 HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01515 HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01498 HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
The immunoproteasome, having been linked to neurodegenerative diseases and hematological cancers, has been shown to play an important role in MHC class I antigen presentation. The development of molecular probes that sel...
TMPK-01428 HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi) Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01449 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi) Human E. coli
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01404 HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated Human E. coli
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01526 HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01453 HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01457 HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01447 HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01461 HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01500 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01517 HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg...
TMPK-01550 HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Monomer Protein, Human, MHC (His & Avi) Human HEK293 Cells
Melanoma-associated antigen 4 is a protein that in humans is encoded by the MAGEA4 gene.The MAGE- A4 antigen is among the most commonly expressed cancer testis antigens. The Human HLA-A*0201 MAGE-A4 (GVYDGREHTV) complex ...
TMPK-01439 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01554 HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
The WT1 protein plays a role in cell growth, the process by which cells mature to perform specific functions (differentiation), and the self-destruction of cells (apoptosis). WT1 is differentially expressed in serous, en...
TMPK-01546 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01454 HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi) Human HEK293 Cells
PRAME (PReferentially expressed Antigen in MElanoma) is a melanoma-associated antigen expressed in cutaneous and ocular melanomas and some other malignant neoplasms, while its expression in normal tissue and benign tumor...
TMPK-01483 HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Alpha-fetoprotein (AFP), a specific liver cancer marker, T cells expressing AFP-CAR selectively degranulated, released cytokines, and lysed liver cancer cells that were HLA-A*02:01 /AFP while sparing cells from multiple ...
TMPK-01497 HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled Human HEK293 Cells
NY-ESO-1 or New York esophageal squamous cell carcinoma 1 is a well-known cancer-testis antigen (CTAs) with re-expression in numerous cancer types. Its ability to elicit spontaneous humoral and cellular immune responses,...
TMPK-01552 HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
p53 is a tumor suppressor protein. Under stressful conditions, p53 tightly regulates cell growth by promoting apoptosis and DNA repair. When p53 becomes mutated, it loses its function, resulting in abnormal cell prolifer...
TMPK-01537 HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Kirsten rat sarcoma 2 viral oncogene homolog (KRAS) is the most commonly mutated oncogene in human cancer. The developments of many cancers depend on sustained expression and signaling of KRAS, which makes KRAS a high-pr...
TMPK-01480 HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated Human HEK293 Cells
Survivin (also known as BIRC5) is an evolutionarily conserved eukaryotic protein that is essential for cell division and can inhibit cell death. Normally it is only expressed in actively proliferating cells, but is upreg...
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CD5 Protein, Mouse, Recombinant (His)
TMPY-01334
Species: Mouse
Expression System: HEK293 Cells
LY6A Protein, Mouse, Recombinant (His)
TMPY-05544
Species: Mouse
Expression System: E. coli
Klrb1a Protein, Mouse, Recombinant (His)
TMPY-02414
Species: Mouse
Expression System: HEK293 Cells
CD86 Protein, Mouse, Recombinant (His)
TMPY-01206
Species: Mouse
Expression System: HEK293 Cells
CD86 Protein, Mouse, Recombinant (hFc)
TMPY-05386
Species: Mouse
Expression System: HEK293 Cells
CD86 Protein, Mouse, Recombinant (His), Biotinylated
TMPY-05133
Species: Mouse
Expression System: HEK293 Cells
MD2/LY96 Protein, Mouse, Recombinant (hFc)
TMPY-03999
Species: Mouse
Expression System: HEK293 Cells
SAP/SH2D1A Protein, Human, Recombinant (His)
TMPY-02440
Species: Human
Expression System: E. coli
Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi)
TMPK-01422
Species: Human
Expression System: HEK293 Cells
APC-equivalent Peptide Ready HLA-A*02:01&B2M Tetramer Protein, Human, MHC (His)
TMPK-01415
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*02:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01421
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*03:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01419
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01425
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*11:01&B2M Monomer Protein, Human, MHC (His & Avi)
TMPK-01426
Species: Human
Expression System: HEK293 Cells
Peptide Ready HLA-A*24:02&B2M Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01409
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01455
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
TMPK-01406
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01432
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MAGE-A1 (KVLEYVIKV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01445
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MART-1 (ELAGIGILTV) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01468
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MAGE-A4 or MAGE-A8 (KVLEHVVRV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01459
Species: Human
Expression System: HEK293 Cells
HLA-A*01:01&B2M&MAGE-A3 (EVDPIGHLY) Monomer Protein, Human, MHC (His & Avi)
TMPK-01495
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12C (VVVGACGVGK) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01433
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01482
Species: Human
Expression System: HEK293 Cells
HLA-A*01:01&B2M&CT83 (NTDNNLAVY) Monomer Protein, Human, MHC (His & Avi)
TMPK-01496
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&LMP2 (CLGGLLTMV) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01530
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01519
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi)
TMPK-01532
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi)
TMPK-01515
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&LMP2 (SSCSSCPLTK) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01498
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVGADGVGK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01428
Species: Human
Expression System: E. coli
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Monomer Protein, Human, MHC (E. coli, His & Avi)
TMPK-01449
Species: Human
Expression System: E. coli
HLA-A*11:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (E. coli, His & Avi), Biotinylated
TMPK-01404
Species: Human
Expression System: E. coli
HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01526
Species: Human
Expression System: HEK293 Cells
HLA-A*03:01&B2M&KRAS G12V (VVVGAVGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01453
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12A (VVVGAAGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01457
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01447
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12S (VVVGASGVGK) Monomer Protein, Human, MHC (His & Avi)
TMPK-01461
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQV) Monomer Protein, Human, MHC (His & Avi)
TMPK-01500
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi)
TMPK-01517
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&MAGE-A4 (GVYDGREHTV) Monomer Protein, Human, MHC (His & Avi)
TMPK-01550
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
TMPK-01439
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&WT-1 (RMFPNAPYL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01554
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01546
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&PRAME (SLLQHLIGL) Tetramer Protein, Human, MHC (His & Avi)
TMPK-01454
Species: Human
Expression System: HEK293 Cells
HLA-A*02:03&B2M&AFP (FMNKFIYEI) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01483
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&NY-ESO-1 (SLLMWITQC) Tetramer Protein, Human, MHC (His & Avi), PE-Labeled
TMPK-01497
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&P53 R175H (HMTEVVRHC) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01552
Species: Human
Expression System: HEK293 Cells
HLA-A*11:01&B2M&KRAS G12D (VVVGADGVGK) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01537
Species: Human
Expression System: HEK293 Cells
HLA-A*02:01&B2M&Survivin (LMLGEFLKL) Monomer Protein, Human, MHC (His & Avi), Biotinylated
TMPK-01480
Species: Human
Expression System: HEK293 Cells
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