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Prasugrel Hydrochloride

Catalog No. T6952   CAS 389574-19-0
Synonyms: LY 640315, PCR 4099 (hydrochloride), Effient Hydrochloride, LY 640315 Hydrochloride, Prasugrel HCl

Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.

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Prasugrel Hydrochloride Chemical Structure
Prasugrel Hydrochloride, CAS 389574-19-0
Pack Size Availability Price/USD Quantity
5 mg In stock $ 39.00
10 mg In stock $ 55.00
25 mg In stock $ 90.00
50 mg In stock $ 133.00
100 mg In stock $ 197.00
1 mL * 10 mM (in DMSO) In stock $ 50.00
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Purity: 99.79%
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Prasugrel Hydrochloride (LY 640315 Hydrochloride) is a piperazine derivative and pletelet aggregation inhibitor that is used to prevent thrombosis in patients with acute coronary syndrome.
Targets&IC50 platelet:1.8 μM.
In vivo Prasugrel significantly inhibits arterio-venous (AV) shunt and electrically induced arterial thrombosis in single dose ranges of 0.3 to 3 mg/kg and of 0.3 and 1 mg/kg/day for multiple doses. These doses are similar to doses with inhibition of platelet activation via P2Y12 receptors, suggesting that the protective effects of prasugrel in these cerebral infarction and peripheral arterial occlusive disease models reflect P2Y12 inhibitions on platelets by prasugrel's active metabolite. Prasugrel also significantly prevents progression of peripheral vascular lesions[1].
Synonyms LY 640315, PCR 4099 (hydrochloride), Effient Hydrochloride, LY 640315 Hydrochloride, Prasugrel HCl
Molecular Weight 409.9
Formula C20H20FNO3S·HCl
CAS No. 389574-19-0

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

H2O: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 43 mg/mL (104.9 mM)

Ethanol: 9 mg/mL (21.95 mM)

TargetMolReferences and Literature

1. Ogawa T, et al. Eur J Pharmacol. 2009, 612(1-3):29-34.

Related compound libraries

This product is contained In the following compound libraries:
Anti-Cancer Drug Library Anti-Cancer Approved Drug Library Anti-Cancer Clinical Compound Library Bioactive Compound Library Clinical Compound Library Drug-induced Liver Injury (DILI) Compound Library Inhibitor Library FDA-Approved Drug Library Bioactive Compounds Library Max Neuronal Signaling Compound Library

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Keywords

Prasugrel Hydrochloride 389574-19-0 GPCR/G Protein Neuroscience P2Y Receptor LY640315 aggregation LY 640315 platelet Inhibitor PCR-4099 antiplatelet LY-640315 Hydrochloride ADP PCR 4099 active PCR4099 PCR 4099 (hydrochloride) metabolite LY640315 Hydrochloride inhibit Effient Hydrochloride LY-640315 Prasugrel LY 640315 Hydrochloride Prasugrel HCl inhibitor

 

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