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DAPT

Catalog No. T6202    CAS 208255-80-5    Synonyms: GSI-IX, LY-374973

DAPT is a novel γ-secretase inhibitor which reduces the Aβ production (IC50: 20 nM in HEK 293 cells) and Aβ42 levels (IC50: 200 nM).

Pack Size Availability Price/USD Quantity
5 mg In stock 60.00
10 mg In stock 100.00
25 mg In stock 190.00
50 mg In stock 340.00
100 mg In stock 540.00
200 mg In stock 860.00
1 mL * 10 mM (in DMSO) In stock 60.00
Bulk Size: Please Quote for Discount Please Quote for Bulk Size
Biological Activity:

Product Description:

DAPT is a novel γ-secretase inhibitor which reduces the Aβ production (IC50: 20 nM in HEK 293 cells) and Aβ42 levels (IC50: 200 nM).

Receptor:

γ secretase(Aβ); Aβ; Aβ42;

Chemical Information:
Molecular Weight 432.46
Formula C23H26F2N2O4
CAS Number 208255-80-5
Solubility

DMSO: 43.2 mg/mL (100 mM), 100 mM

Water: Insoluble

( < 1 mg/ml refers to the product slightly soluble or insoluble )
Storage store at -80°C
Remark For obtaining a higher solubility , please warm the tube at 37 ℃ and shake it in the ultrasonic bath for a while.Stock solution can be stored below -20 ℃ for several month.