110
10
11
1
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T29670 | ADR-925 | ICRF198,ICRF-198,ADR 925,ICRF 198,ADR925 | Endogenous Metabolite |
ADR-925 (ICRF 198), an active chelated iron metabolite of dexrazoxane, has the ability to protect neonatal rat cardiomyocytes from adriamycin-induced injury. | |||
T23642 | ADR-851 free base | ADR851 free base | |
ADR-851 free base is an antagonist of the HT3 receptor. | |||
T23642L | ADR-851 HCl | Adr-851,Adr 851,Adr851 | |
ADR-851 HCl is an HT3 receptor antagonist. It works against mechanical, acute thermal, and formalin-induced inflammatory pain. | |||
T23641 | ADR 882 | ADR882,ADR-882 | |
ADR 882 is an antagonist of the 5-HT3 receptor. It has analgesic properties. | |||
T6467 | Cardioxane | ADR-529 Hydrochloride,ICRF-187 hydrochloride,ADR-529,Dexrazoxane HCl,Cardioxane hydrochloride,ICRF-187 | Topoisomerase |
Cardioxane (ADR-529) is a cardio-protective drug. | |||
T22305 | Dexrazoxane | ICRF-187 | Others |
Dexrazoxane (ICRF-187) is an anticancer drug used to block mitosis and arrest dividing cells. It is an iron chelator and provides cardioprotection against anthracycline toxicity. | |||
T9244 | σ1 Receptor antagonist-1 | Sigma receptor | |
σ1 Receptor antagonist-1 is a selective sigma 1 receptor antagonist. | |||
T6018 | Zosuquidar trihydrochloride | Zosuquidar (LY335979) 3HCl,RS 33295-198 trihydrochloride,RS 33295-198 (D06387) 3HCl,Zosuquidar 3HCl,LY-335979 trihydrochloride | P-gp |
Zosuquidar trihydrochloride (LY-335979 trihydrochloride) is a potent modulator of P-glycoprotein-mediated multi-drug resistance with Ki of 60 nM. Phase 3. | |||
T8231 | Adrenocorticotropic Hormone (ACTH) (1-39), human | ACTH (1-39), human | Others |
Adrenocorticotropic Hormone (ACTH) (1-39), human (ACTH (1-39), human) is an agonist of melanocortin receptor. | |||
T26939 | Cadralazine | ISF 2469,ISF-2469,ISF2469 | Others |
Cadralazine (ISF 2469) is a peripheral arteriolar vasodilator and can be used in studies about acting as an antihypertensive drug. | |||
T7197 | Fadrozole | Aromatase | |
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM) | |||
T7567L | Adrenorphin 3TFA(88377-68-8(free base)) | Metorphamide | Opioid Receptor |
Adrenorphin 3TFA(88377-68-8(free base)) (Metorphamide) is an agonist of μ-opioid receptor(Ki :12 nM). | |||
T0366 | Cefadroxil | BL-S 578 | Antibacterial , Antibiotic |
Cefadroxil (BL-S 578) is a Cephalosporin Antibacterial. The chemical classification of cefadroxil anhydrous is Cephalosporins. | |||
TQ0053 | Fadraciclib | CYC065 | CDK |
Fadraciclib (CYC065) is an orally available, second-generation ATP-competitive inhibitor of CDK2/CDK9 kinases (IC50s: 5/26 nM). | |||
T7556 | Fadrozole hydrochloride | CGS 16949A | Aromatase |
Fadrozole hydrochloride (CGS 16949A) is a model aromatase inhibitor that has been shown to suppress estrogen production in the ovaries of fish. | |||
T68599 | Orphenadrine | Orphenadrine (free base) | Sodium Channel , NMDAR , AChR |
Orphenadrine is a noncompetitive N-methyl-D-aspartate (NMDA) receptor antagonist that inhibits clonal HERG channels in a concentration-dependent manner, producing an IC of 0.85 μM in HEK cells.Orphenadrine is an antagoni... | |||
TP1244L1 | Adrenocorticotropic Hormone (ACTH) (1-10), human acetate | Adrenocorticotropic Hormone (ACTH) (1-10), human acetate(2791-05-1 Free base) | Others |
Adrenocorticotropic Hormone (ACTH) (1-10), human acetate is a fragment of adrenocorticotropin hormone. Adrenocorticotropic Hormone (ACTH) (1-10), human acetate possesses a weak α-MSH potency only at 100 and 1000 nM. | |||
T7627L | Adrenocorticotropic Hormone (ACTH) (4-10) TFA | Adrenocorticotropic Hormone (ACTH) (4-10) TFA(4037-01-8(free base)),Acth (4-10) | Melanocortin Receptor |
Adrenocorticotropic Hormone (ACTH) (4-10) TFA (Acth (4-10)) is an agonist of potent melanocortin(MC4R) receptor . | |||
T1308 | Orphenadrine hydrochloride | Mebedrol,Mephenamin | Sodium Channel , NMDAR , Norepinephrine , iGluR , Histamine Receptor |
Orphenadrine hydrochloride (Mephenamin) is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. | |||
T70047 | Bedoradrine | Bedoradrine free base | Adrenergic Receptor |
Bedoradrine free base is a novel, highly selective β2-adrenoceptor agonist for the treatment of asthma and chronic obstructive pulmonary disease (COPD). | |||
T2558 | Cladribine | 2-chlorodeoxyadenosine,2-Chloro-2′-deoxyadenosine,CldAdo,2CdA | Apoptosis , Adenosine deaminase |
Cladribine (2CdA), an adenosine deaminase inhibitor, is utilized in the treatment of lymphoproliferative diseases. | |||
TP1240 | Adrenocorticotropic Hormone (ACTH) (18-39), human TFA | CLIP (human) (TFA) | Others |
Adrenocorticotropic Hormone (ACTH) (18-39), human TFA (CLIP human TFA) is a corticotropinlike intermediate lobe peptide, it is is produced in the melanotrophs of the intermediate lobe of the pituitary. | |||
T76664 | Adropin (34-76) (human, mouse, rat) | ||
Adropin (34-76) (human, mouse, rat) is a peptide that attenuates liver fibrosis and insulin resistance independent of obesity or food intake. | |||
T3628 | Madrasin | DDD00107587 | DNA/RNA Synthesis |
Madrasin (DDD00107587) is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. | |||
T2206 | Quadrol | N,N,N′,N′-Tetrakis(2-hydroxypropyl)ethylenediamine,EDTP,Edetol | Others |
Quadrol (EDTP) is an immunostimulant, accelerated wound healing. | |||
T20094 | Adrenochrome | Adraxone | Antioxidant |
Adrenochrome (Adraxone) is a cytotoxic molecule that can be used to kill bacteria. Adrenochrome is an oxidized product of Epinephrine. Adrenochrome is a coronary systolic compound that acts on rat hearts and is associate... | |||
T10003 | α1 adrenoceptor-MO-1 | Others | |
α1 adrenoceptor-MO-1 (S enantiomer) has affinity at alpha 1 adrenergic receptor with alphalytic activity and analgesic action. It has more active than R enantiomer. | |||
T0948 | Adrenalone hydrochloride | Adrenalone HCl | Adrenergic Receptor |
Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a loc... | |||
T6618 | Orphenadrine Citrate | Flexon,Flexoject,Banflex | AChR , iGluR |
Orphenadrine Citrate (Flexon) is a skeletal muscle relaxant, it acts in the central nervous system to produce its muscle relaxant effects. | |||
T26760 | Bedoradrine sulfate | KUR1246,MN 221 sulfate,KUR1246 sulfate,MN221 sulfate,KUR 1246 sulfate,MN-221 sulfate,KUR 1246,KUR-1246 sulfate,MN-221,MN 221,MN221,KUR-1246 | Adrenergic Receptor |
Bedoradrine sulfate (MN-221 sulfate) is a super-selective beta2 agonist for the treatment of asthma exacerbations and chronic obstructive pulmonary disease. | |||
T0871 | Noradrenaline bitartrate | Adrenergic Receptor | |
Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors. Norepinephrine Bitartrate is a bitartrate salt of norepinephrine, a synthetic phenylethylamine that mimics the sympathomimetic actions of the ... | |||
TP1257L | Adrenomedullin (AM) (22-52), human acetate | Adrenomedullin (AM) (22-52), human acetate(159899-65-7 Free base) | CGRP Receptor |
Adrenomedullin (AM) (22-52), human acetate is an antagonist of calcitonin generelated peptide receptor in the hindlimb vascular bed of the cat and an adrenomedullin receptor. | |||
T69651 | Adrixetinib | ||
Adrixetinib is an inhibitor of protein tyrosine kinase with antineoplastic activity . | |||
T32748 | Lidadronic Acid | Lidadronate | |
Lidadronic Acid is a bioactive chemical. | |||
T7197L | Fadrozole HCl hydrate | Fadrozole,CGS-16949A,Fadrozole hydrochloride hemihydrate,CGS16949A,CGS 16949A | |
Fadrozole is a selective inhibitor of aromatase. It also effective in the treatment of estrogen-dependent diseases including breast cancer. | |||
T38424 | (R)-Fadrozole | FAD286,(R)-CGS 16949A free base,(R)-Fadrozole | |
(R)-Fadrozole ((R)-CGS 16949A; FAD286) is a potent nonsteroidal inhibitor. (R)-Fadrozole also inhibits human placental aromatase (pIC 50 = 6.17) and aldosterone biosynthesis. (R)-Fadrozole reverses cardiac fibrosis in sp... | |||
T80503 | Proadrenomedullin (N-20) (bovine, porcine) | ProADM N20(bovine, porcine),PAMP-20(bovine, porcine) | |
Proadrenomedullin (N-20) (ProADM N20) (bovine, porcine) is a peptide known for its strong hypotensive effects and inhibition of catecholamine release from chromaffin cells without competing with other substances. It effe... | |||
T36405 | Pro-Adrenomedullin (153-185), human | Pro-Adrenomedullin (153-185), human,H2N-Ser-Leu-Pro-Glu-Ala-Gly-Pro-Gly-Arg-Thr-Leu-Val-Ser-Ser-Lys-Pro-Gln-Ala-His-Gly-Ala-Pro-Ala-Pro-Pro-Ser-Gly-Ser-Ala-Pro-His-Phe-Leu-OH | |
Pro-Adrenomedullin(153-185),human, (C143H224N42O43), a peptide with the sequence H2N-SLPEAGPGRTLVSSKPQAHGAPAPPSGSAPHFL-OH, MW= 3219.6. Adrenomedullin (AM) is a ubiquitously expressed peptide initially isolated from phaec... | |||
TP1486 | Adrenomedullin (16-31), human | ||
Adrenomedullin (16-31), human is amino acid residues 16-31 fragment of human adrenomedullin (hADM). | |||
TP2214 | Adrenomedullin (1-12), human | Others | |
Adrenomedullin (AM) (1-12), human, is a peptide with the sequence Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu-Arg. Adrenomedullin (AM) (1-12), human, was initially identified as a vasodilator, and as such, it has the abi... | |||
TP1256 | Adrenomedullin (AM) (22-52), human TFA | 22-52-Adrenomedullin (human) (TFA) | |
Adrenomedullin (AM) (22-52), human (22-52-Adrenomedullin human) TFAis a kind of NH2 TFA truncated at the end of the quality of adrenal medullary analogue, is a kind of quality of adrenal medullary receptor antagonist. | |||
T7627 | Adrenocorticotropic Hormone (ACTH) (4-10), human | Adrenocorticotropic Hormone (ACTH) (4-10),ACTH (4-10), human,Acth (4-10) | Melanocortin Receptor |
Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor . | |||
TP1146 | Adrenomedullin (AM) (1-52), human | Human adrenomedullin-(1-52)-NH2 | |
Adrenomedullin (AM) (1-52), human is a 52-amino acid peptide that modulates cellular proliferation and angiogenesis in cancer. | |||
T35851 | Etzadroxil | Ethyl 2-Ethylbutyrate | Antibacterial |
Etzadroxil (Ethyl 2-Ethylbutyrate) is an orally available and volatile esterification.Etzadroxil has broad-spectrum antimicrobial activity for the treatment of urinary tract infections caused by multi-drug resistant bact... | |||
T32536 | L-Adrenalin ascorbinate | Tonhormon | |
l-Adrenalin ascorbinate is a bioactive chemical. | |||
T36817 | Quadrone | ||
Quadrone is a sesquiterpene originally isolated from A. terreus. It is cytotoxic to human carcinoma KB cells in vitro (EC50 = 1.3 μg/ml). | |||
T31212 | Dazadrol maleate | Sch 12650,Sch-12650,Sch12650 | |
Dazadrol maleate, also known as Sch-12650, is a bio-active chemical. | |||
T72091 | ADRA1D receptor antagonist 1 free base | ||
ADRA1D receptor antagonist 1 (free base) antagonist ( K i =1.6 nM). ADRA1D receptor antagonist 1 (free base) dose-dependently inhibits bladder contraction with an IC 30 value of 15 nM. ADRA1D receptor antagonist 1 (free... | |||
T68941 | Dioxadrol | ||
Dioxadrol is a dissociative anaesthetic drug which has been found to be an NMDA antagonist and produces similar effects to PCP in animals. | |||
T9097 | Guanadrel | Others | |
Guanadrel is an antihypertensive agent. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T19768 | γ-Tocotrienol | gamma Tocotrienol,gammaTocotrienol,gamma-Tocotrienol,D-gamma-Tocotrienol,Plastochromanol | Others |
γ-Tocotrienol (Plastochromanol) is one of the four types of tocotrienol, a type of vitamin E. Itl is also a radioprotector, antioxidant. It shows antitumor and antihypertensive effects in vivo. | |||
T1071L | DL-Adrenaline Hydrochloride | Adrenergic Receptor | |
DL-Adrenaline Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing activities. | |||
T19180 | Adrenic Acid | cis-7,10,13,16-Docosatetraenoic acid | Endogenous Metabolite |
Adrenic Acid (cis-7,10,13,16-Docosatetraenoic acid) is a member of the class of compounds known as very-long-chain fatty acids. Adrenic Acid can be found in blood and in human myelin tissue. | |||
T2207 | Adrenosterone | 11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G | Androgen Receptor , Endogenous Metabolite |
Adrenosterone (11-ketoandrostenedione) is a steroid hormone isolated from the adrenal cortex. | |||
T20173 | Noradrenaline tartrate | NSC 169106,NSC-169106,l-Noradrenaline d-bitartrate,NSC169106,Norepinephrine bitartrate | |
Norepinephrine bitartrate is a precursor of epinephrine. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceru... | |||
T5132 | 9-dihydro-13-acetylbaccatin III | 13-Acetyl-9-dihydrobaccatin III,9-DHAB III | Apoptosis |
9-dihydro-13-acetylbaccatin III (9-DHAB III)is an apoptosis inducer. It shows cytotoxicity against the MCF7 cell line and drug-resistant cell line MCF7-ADR. | |||
T4085 | Paris saponin VII | Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII | Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy |
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation. | |||
T4A2399 | Cinobufotalin | IL Receptor , Akt , MRP , P-gp | |
Cinobufotalin is a main cardiac toxin in toad, it is a novel anti-HCC agent, it induces growth inhibition and apoptosis in cultured HCC cells through ceramide production. Cinobufotalin is also an effective reversal agent... | |||
T83368 | 3,5-Dimethoxy-2,7-phenanthrenediol | ||
3,5-Dimethoxy-2,7-phenanthrenediol (compound 2), extracted from Combretum laxum roots, exhibits cytotoxicity against various human cancer cell lines, including 786-0, MCF-7, and NCI/ADR-RES, with corresponding IC50 value... | |||
TN5153 | Torilin | MMP , ERK , IκB/IKK , p38 MAPK , NF-κB , Tyrosinase , Reductase , DNA/RNA Synthesis , JNK | |
Torilin is an inhibitor of testosterone 5 alpha-reductase, it (IC50 = 31.7 +/- 4.23 microM) shows a stronger inhibition of 5 alpha-reductase than alpha-linolenic acid (IC50 = 160.3 +/- 24.62 microM) but is weaker than fi... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-02438 | AKR1B1 Protein, Human, Recombinant (His) | Human | E. coli |
Aldose reductase (AKR1B1) belongs to the aldo/keto reductase superfamily. AKR1B1 is a NADPH-dependent aldo-keto reductase best known as the rate-limiting enzyme of the polyol pathway. Expression of AKR1B1 was the highest... | |||
TMPY-02121 | CXADR/CAR Protein, Human, Recombinant (His) | Human | HEK293 Cells |
CXADR/CAR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.6 kDa and the accession number is P78310-1. | |||
TMPY-00738 | CXADR/CAR Protein, Mouse, Recombinant (His & hFc) | Mouse | HEK293 Cells |
CXADR/CAR Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 52 kDa and the accession number is P97792-1. | |||
TMPH-00288 | Adrenodoxin reductase Protein, Bovine, Recombinant (His) | Bovine | P. pastoris (Yeast) |
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitam... | |||
TMPY-01939 | CXADR/CAR Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
CXADR/CAR Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.7 kDa and the accession number is P97792-1. | |||
TMPH-00220 | Adrenodoxin, mitochondrial Protein, Bovine, Recombinant (His) | Bovine | E. coli |
Essential for the synthesis of various steroid hormones. Participates in the reduction of mitochondrial cytochrome P450 for steroidogenesis. Transfers electrons from adrenodoxin reductase to CYP11A1, a cytochrome P450 th... | |||
TMPH-00287 | Adrenodoxin reductase Protein, Bovine, Recombinant (E. coli, His) | Bovine | E. coli |
Serves as the first electron transfer protein in all the mitochondrial P450 systems including cholesterol side chain cleavage in all steroidogenic tissues, steroid 11-beta hydroxylation in the adrenal cortex, 25-OH-vitam... | |||
TMPY-00739 | CXADR/CAR Protein, Human, Recombinant (His & hFc) | Human | HEK293 Cells |
CXADR/CAR Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 52 kDa and the accession number is P78310-1. | |||
TMPJ-00236 | CXADR/CAR Protein, Mouse, Recombinant (Avi & His), Biotinylated | Mouse | HEK293 Cells |
CXADR/CAR Protein, Mouse, Recombinant (Avi & His), Biotinylated is expressed in HEK293 mammalian cells with C-Avi-6xHis tag. The predicted molecular weight is 30-40 KDa and the accession number is P97792. | |||
TMPY-02839 | Adrenomedullin Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Adrenomedullin consists of 52 amino acids and is a member of the adrenomedullin family. It s a a hypotensive peptide and has 1 intramolecular disulfide bond. It seems that adrenomedullin has a slight homology with the ca... | |||
TMPJ-00237 | CXADR/CAR Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
CXADR/CAR Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 50-70 KDa and the accession number is P97792. |
Cat No. | Product Name | ||
---|---|---|---|
L2700 | Adrenergic Receptor-Targeted Compound Library | 193 compounds | |
A unique collection of 193 bioactive compounds specifically targeting adrenergic receptors, effective tool for screening new drugs or new target identification; |