Powder: -20°C for 3 years
In solvent: -80°C for 2 years
Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
Description | Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM) |
Targets&IC50 | Aromatase:6.4 nM |
In vivo | Fadrozole is a model aromatase inhibitor that shown to suppress estrogen production in the ovaries of fish. |
Animal Research | Adult female fathead minnows (Pimephales promelas) were exposed via water to 0, 5, or 50μg fadrozole/L for a time-course of 0.5, 1, 2, 4, and 6h, or 0 or 50μg fadrozole/L for a time-course of 6, 12, and 24h. Examined ex vivo ovarian 17β-estradiol (E2) and testosterone (T) production, and plasma E2 concentrations from each study. |
Molecular Weight | 223.279 |
Formula | C14H13N3 |
CAS No. | 102676-47-1 |
Powder: -20°C for 3 years
In solvent: -80°C for 2 years
DMSO: 100 mg/mL (447.89 mM)
( < 1 mg/ml refers to the product slightly soluble or insoluble )
You can also refer to dose conversion for different animals. More
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Fadrozole 102676-47-1 内分泌与激素 Aromatase (Rac)-FAD286 inhibit CGS 16949A Inhibitor inhibitor