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Fadrozole

Catalog No. T7197 CAS 102676-47-1

Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)

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Fadrozole, CAS 102676-47-1

Pack Size	Availability	Price/USD
5 mg	In stock	$ 45.00
10 mg	In stock	$ 68.00
25 mg	In stock	$ 130.00
50 mg	In stock	$ 227.00
100 mg	In stock	$ 402.00
1 mL * 10 mM (in DMSO)	In stock	$ 50.00

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Fadrozole is a nonsteroidal aromatase inhibitor with potential antineoplastic activity(IC50 : 6.4 nM)
Targets&IC50	Aromatase:6.4 nM
In vivo	Fadrozole is a model aromatase inhibitor that shown to suppress estrogen production in the ovaries of fish.
Animal Research	Adult female fathead minnows (Pimephales promelas) were exposed via water to 0, 5, or 50μg fadrozole/L for a time-course of 0.5, 1, 2, 4, and 6h, or 0 or 50μg fadrozole/L for a time-course of 6, 12, and 24h. Examined ex vivo ovarian 17β-estradiol (E2) and testosterone (T) production, and plasma E2 concentrations from each study.

Molecular Weight	223.27
Formula	C14H13N3
CAS No.	102676-47-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 100 mg/mL (447.89 mM)

References and Literature

1. Schroeder A L , Ankley G T , Habib T , et al. Rapid Effects of the Aromatase Inhibitor Fadrozole on Steroid Production and Gene Expression in the Ovary of Female Fathead Minnows ( Pimephales promelas )[J]. General and Comparative Endocrinology, 2017:S0016648017301521.

Related compound libraries

This product is contained In the following compound libraries：

Inhibitor Library Anti-Cancer Active Compound Library Anti-Cancer Approved Drug Library Drug Repurposing Compound Library Anti-Cancer Drug Library Approved Drug Library Human Metabolite Library Drug-induced Liver Injury (DILI) Compound Library Bioactive Compound Library ReFRAME Related Library

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Keywords

Fadrozole 102676-47-1 Endocrinology/Hormones Aromatase (Rac)-FAD286 inhibit CGS 16949A Inhibitor inhibitor

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