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Adrenocorticotropic Hormone (ACTH) (4-10), human

Catalog No. T7627   CAS 4037-01-8
Synonyms: Adrenocorticotropic Hormone (ACTH) (4-10), ACTH (4-10), human, Acth (4-10)

Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .

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Adrenocorticotropic Hormone (ACTH) (4-10), human Chemical Structure
Adrenocorticotropic Hormone (ACTH) (4-10), human, CAS 4037-01-8
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
In vivo In humans, Adrenocorticotropic Hormone (ACTH) (4-10)?enters the cerebral fluid compartment after intranasal application and leads to a?decrease in total body fat after 6 weeks of continuous treatment[1].
Synonyms Adrenocorticotropic Hormone (ACTH) (4-10), ACTH (4-10), human, Acth (4-10)
Molecular Weight 962.09
Formula C44H59N13O10S
CAS No. 4037-01-8

Storage

keep away from moisture

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 10 mM

TargetMolReferences and Literature

1. Wellhöner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8. 2. Krude H , Biebermann H , Schnabel D , et al. Obesity Due to Proopiomelanocortin Deficiency: Three New Cases and Treatment Trials with Thyroid Hormone and ACTH4–10[J]. The Journal of Clinical Endocrinology & Metabolism, 2003, 88(10):4633-4640.

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Keywords

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