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Adrenocorticotropic Hormone (ACTH) (4-10), human

Catalog No. T7627 CAS 4037-01-8

Synonyms: Acth (4-10), ACTH (4-10), human, Adrenocorticotropic Hormone (ACTH) (4-10)

Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .

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Adrenocorticotropic Hormone (ACTH) (4-10), human, CAS 4037-01-8

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Adrenocorticotropic Hormone (ACTH) (4-10) is an agonist of potent melanocortin(MC4R) receptor .
In vivo	In humans, Adrenocorticotropic Hormone (ACTH) (4-10)?enters the cerebral fluid compartment after intranasal application and leads to a?decrease in total body fat after 6 weeks of continuous treatment[1].

Synonyms	Acth (4-10), ACTH (4-10), human, Adrenocorticotropic Hormone (ACTH) (4-10)
Molecular Weight	962.09
Formula	C44H59N13O10S
CAS No.	4037-01-8

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. P Wellhöner, R Hörster, Jacobs F , et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue.[J]. International Journal of Obesity, 2012, 36(5):703. 1. Wellhöner P, et al. Intranasal application of the melanocortin 4 receptor agonist MSH/ACTH(4-10) in humans causes lipolysis in white adipose tissue. Int J Obes (Lond). 2012 May;36(5):703-8. 2. Krude H , Biebermann H , Schnabel D , et al. Obesity Due to Proopiomelanocortin Deficiency: Three New Cases and Treatment Trials with Thyroid Hormone and ACTH4–10[J]. The Journal of Clinical Endocrinology & Metabolism, 2003, 88(10):4633-4640.

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Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Keywords

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