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Orphenadrine hydrochloride

Catalog No. T1308 CAS 341-69-5

Synonyms: Mebedrol, 盐酸邻甲苯海拉明, Mephenamin

Orphenadrine hydrochloride is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.

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Orphenadrine hydrochloride, CAS 341-69-5

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Purity: 98%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Orphenadrine hydrochloride is a muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm.
Targets&IC50	N-methyl-D-aspartate (NMDA) receptor:6.0 ±0.7 μM (Ki)

Synonyms	Mebedrol, 盐酸邻甲苯海拉明, Mephenamin
Molecular Weight	305.85
Formula	C18H24ClNO
CAS No.	341-69-5

Storage

Powder: -20°C for 3 years

In solvent: -80°C for 2 years

Solubility Information

DMSO: 10 mM

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Kornhuber J, et al. J Neural Transm Gen Sect. 1995;102(3):237-46.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Compound Library GPCR Compound Library Anti-Cardiovascular Disease Compound Library Histamine & Melatonin Receptor-Targeted Compound Library Neurotransmitter Receptor Compound Library Anti-Parkinson's Disease Compound Library Inhibitor Library Drug-induced Liver Injury (DILI) Compound Library Sodium Channel Blocker Library Immunology/Inflammation Compound Library

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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Keywords

Orphenadrine hydrochloride 341-69-5 G蛋白偶联受体离子通道免疫与炎症神经科学 Histamine Receptor iGluR NMDAR Norepinephrine Sodium Channel Ionotropic glutamate receptors Mephenamin spasticity HSP27 parkinson's syndrome PBR Inhibitor inhibit CGC cells neuroprotective properties Mebedrol Orphenadrine inhibitor

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