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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6829 | EPI-001 | EPI001,EPI 001 | Apoptosis , Androgen Receptor , PPAR |
EPI-001 is an androgen receptor N-terminal domain antagonist with IC50 of ~6 μM and a selective PPAR-gamma modulator. | |||
T28502 | Ralaniten | EPI-002 | Androgen Receptor |
Ralaniten (EPI-002) is a potent, specific, and orally active antagonist of the androgen receptor N-terminal structural domain (AR-NTD).Ralaniten inhibits AR transcriptional activity with an IC50 value of 7.4 μM.Ralanites... | |||
T37970 | 12-epi Leukotriene B4 | 12-epi Leukotriene B4 | |
Leukotriene B4 (LTB4) compounds are produced by both enzymatic and non-enzymatic processes. The products of enzymatic origin, via Leukotriene A4 (LTA4) hydrolase, are stereospecifically 12(R). Non-enzymatic hydrolysis pr... | |||
T36919 | 1α-Hydroxy-3-epi-vitamin D3 | 1α-Hydroxy-3-epi-vitamin D3 | |
1α-Hydroxy-3-epi-vitamin D3, a natural metabolite derived from 1alpha,25-dihydroxyvitamin D3, effectively suppresses parathyroid hormone (PTH) secretion[1]. | |||
TQ0247 | 7-Epi-docetaxel | 7-Epidocetaxel,4-epi-Docetaxel,7-Epitaxotere | Others |
7-Epi-10-oxo-docetaxel (7-Epitaxotere) is a impurity of docetaxel. | |||
T35500 | 3-epi-25-hydroxy Vitamin D3 | 3-epi-25-hydroxy Vitamin D3 | |
3-epi-25-hydroxy Vitamin D3is the C-3 epimer of 25-hydroxy vitamin D3.1Dietary administration of 3-epi-25-hydroxy vitamin D3(0.5 and 1 IU/g) decreases levels of serum parathyroid hormone (PTH) in male, but not female, we... | |||
T11214 | EPI-589 | Others | |
EPI-589, a quinone derivative and oxidoreductase enzyme inhibitor, is considered safe and well tolerated, showing promise for the treatment of amyotrophic lateral sclerosis (ALS). | |||
T36595 | 4-epi-Chlortetracycline (hydrochloride) | ||
Chlortetracycline is an analog of tetracycline , a broad spectrum antibiotic. In addition to its actions against microorganisms, chlortetracycline suppresses inflammation by inhibiting neutrophil action and other aspects... | |||
T37001 | 7-epi Maresin 1 | ||
7-epi Maresin 1 is the inactive 7(S) epimer of Maresin 1 , which contains a 7(R) hydroxyl group. It can be used as an experimental negative control. | |||
T72726 | 3-epi-Vitamin D3 | Epicholecalciferol | |
3-epi-Vitamin D3 (Epicholecalciferol), an analogue of Vitamin D3, serves as a Hedgehog pathway inhibitor, exhibiting potency with an IC50 value of 39.2 μM in U87MG cells. | |||
T37396 | 13-epi-12-oxo Phytodienoic Acid | ||
13-epi-12-oxo Phytodienoic acid (13-epi-12-oxo PDA) is a lipoxygenase metabolite of α-linolenic acid in the leaves of green plants such as corn. ω-3 and ω-6 polyunsaturated fatty acids in plants are substrates for plant ... | |||
T19163 | 7-Epi-10-oxo-docetaxel | Docetaxel Impurity 2 | Others |
7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is an impurity of docetaxel detected by HPLC. | |||
T63811 | EPI-7170 | ||
EPI-7170 is a ralaniten analogue and a potent antagonist of the androgen receptor N-terminal structural domain, blocking the transcriptional activity of the full-length AR (FL-AR) and AR splice variants (AR-Vs). EPI-7170... | |||
T126054 | Epi-Cryptoacetalide | ||
Epi-Cryptoacetalide is a useful organic compound for research related to life sciences and the catalog number is T126054. | |||
T83763 | EPI-X4 TFA | Endogenous Peptide Inhibitor of CXCR4 | |
EPI-X4, an endogenous peptide fragment of human serum albumin (amino acids 408-423), serves as an antagonist to the chemokine (C-X-C motif) receptor 4 (CXCR4). It effectively prevents calcium mobilization and receptor in... | |||
T131585 | 7-Epi-paradisiol | ||
7-Epi-paradisiol is a useful organic compound for research related to life sciences and the catalog number is T131585. | |||
T75496 | 19-epi-Scholaricine | ||
19-epi-Scholaricine, an orally active indole alkaloid, downregulates collagen fibrosis expression and enhances superoxide dismutase (SOD) activities. | |||
T77294 | 1-epi-Regadenoson | ||
1-epi-Regadenoson is an α-isomer impurity of Regadenoson, a highly selective adenosine A2A receptor agonist [1]. | |||
T131516 | Isopropyl-epi-isoobacunoate | ||
Isopropyl-epi-isoobacunoate is a useful organic compound for research related to life sciences and the catalog number is T131516. | |||
T72998 | L-Afegostat | 5-epi-Isofagomine | |
L-Afegostat (5-epi-Isofagomine), a glycosidase inhibitor and an iminosugar, is utilized in carbohydrate synthesis. It demonstrates β-Glucosidase inhibition with a Ki of 30 μM. | |||
T73671 | 7β-Hydroxy-epi-androsterone | ||
7β-Hydroxy-epi-androsterone (7β-Hydroxy-EpiA) is an endogenous androgenic derivative of dehydroepiandrosterone that possesses the ability to bind to ERβ, offering both anti-inflammatory and neuroprotective properties [1]... | |||
T33536 | Mycarose | 3-Epi-axenose | |
Mycarose is a sugar epi-axenose to lyxo configeration. | |||
T124075 | 8-epi-Chlorajapolide F | ||
8-epi-Chlorajapolide F is a useful organic compound for research related to life sciences and the catalog number is T124075. | |||
T124413 | 3-Epi-beta-amyrin | ||
3-Epi-beta-amyrin is a useful organic compound for research related to life sciences. The catalog number is T124413 and the CAS number is 6811-63-8. | |||
T75535 | 5-epi-Arvestonate A | ||
5-epi-Arvestonate A, a sesquiterpenoid extracted from Seriphidium transiliense whole plants, enhances melanogenic production by stimulating MITF and tyrosinase family gene transcription. Additionally, it suppresses IFN-γ... | |||
T35040 | Vatiquinone | EPI-743,EPI743,alpha-Tocotrienol quinone. ATQ3,EPI 743 | |
Vatiquinone, also known as EPI 743, is an orally bioavailable para-benzoquinone being developed for inherited mitochondrial diseases. The mechanism of action of EPI-743 involves augmenting the synthesis of glutathione, o... | |||
T125334 | 15-Epi-Danshenol-A | ||
15-Epi-Danshenol-A is a useful organic compound for research related to life sciences and the catalog number is T125334. | |||
T124591 | 3-Epi-alpha-amyrin | ||
3-Epi-alpha-amyrin is a useful organic compound for research related to life sciences. The catalog number is T124591 and the CAS number is 5937-48-4. | |||
T69093 | Epirubicin | IMI-28,4-epi DX,4'-Epidoxorubicin,IMI 28,4-epidoxorubicin,epi DX,4-epiadriamycin | |
Epirubicin (4'-Epidoxorubicin), a semisynthetic L-arabino derivative of doxorubicin, serves as an antineoplastic agent primarily by inhibiting Topoisomerase, thereby impeding DNA and RNA synthesis. Additionally, it funct... | |||
T72144 | 6-trans-12-epi-Leukotriene B4 | ||
6-trans-12-epi-Leukotriene B4, a metabolite of arachidonic acid, serves as a potent anti-inflammatory agent. | |||
T32848 | Lokysterolamine B | N-Acetyl-4beta-hydroxy-epi-plakinamine A | |
Lokysterolamine B is a steroidal alkaloid isolated from a sponge, Corticium sp. | |||
TNU0789 | 3-epi-Azido-3-deoxythymidine | ||
3’-N-modified nucleoside; Azido-nucleoside | |||
T124173 | 18-Beta-hydroxy-3-epi-alpha-yohimbine | ||
18-Beta-hydroxy-3-epi-alpha-yohimbine is a useful organic compound for research related to life sciences and the catalog number is T124173. | |||
T36164 | 8-iso Prostaglandin F3α | 8-iso Prostaglandin F3α,8-epi PGF3α | |
8-iso PGF3α is an isoprostane produced from the free-radical peroxidation of EPA. Little is known about the biological activity of 8-iso PGF3α. There is one report that it is inactive in a TP receptor mediated assay of h... | |||
T71606 | RO5073012 | ||
RO5073012 is a novel potent and selective TAAR1 partial agonist. | |||
T71046 | FK-1052 | ||
FK-1052 is a serotonin 3 & 4 dual receptor antagonist. | |||
T37149 | Carbamazepine 10,11-epoxide | Others | |
Carbamazepine 10,11-epoxide is an active metabolite of the anticonvulsant carbamazepine.1,2It is formed from carbamazepine by the cytochrome P450 (CYP) isoforms CYP3A4 and CYP2C8 in microsomes prepared from HepG2 cells e... | |||
T8987 | Epiblastin A | Casein Kinase | |
Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs). | |||
T23380 | Sonepiprazole | Dopamine Receptor | |
Sonepiprazole (PNU-101387G) is a chemical compound known for its selective antagonistic properties toward D4 dopamine receptors, exhibiting dissociation constants (Kis) of 3.6 nM and 10.1 nM for rat D4 (rD4) and human D4... | |||
T0943 | Carbamazepine | NSC 169864 | Mitophagy , Sodium Channel , Autophagy |
Carbamazepine (NSC-169864) is a tricyclic compound chemically related to tricyclic antidepressants (TCA) with anticonvulsant and analgesic properties. Carbamazepine exerts its anticonvulsant activity by reducing polysyna... | |||
T0946 | Mepivacaine hydrochloride | Mepivacaine HCl | Sodium Channel |
Mepivacaine hydrochloride (Mepivacaine HCl) is the hydrochloride salt form of mepivacaine, an amide derivative with local anesthetic properties. | |||
T8679 | Epidermal Growth Factor | EGFR | |
Epidermal Growth Factor binds to epidermal growth factor receptor (EGFR) and stimulates cell growth and proliferation. It is approved for the treatment of diabetic foot ulcers. | |||
T10961 | Darenzepine | AChR | |
Darenzepine is a muscarinic receptor inhibitor. | |||
T50014 | 2-methyl-2,3,4,5-tetrahydro-1,5-benzothiazepin-4-one | Epigenetic Reader Domain | |
2-methyl-2,3-dihydro-1,5-benzothiazepin-4(5H)-one is ligand of CBP. | |||
T6864 | Ixabepilone | BMS 247550,Ixempra,Azaepothilone B,BMS 247550-1 | Apoptosis , Microtubule Associated |
Ixabepilone (Azaepothilone B) is an orally bioavailable microtubule inhibitor. It binds to tubulin and promotes tubulin polymerization and microtubule stabilization, thereby arresting cells in the G2-M phase of the cell ... | |||
T0440 | Oxcarbazepine | GP 47680 | Apoptosis , Sodium Channel |
Oxcarbazepine (GP 47680) is an Anti-epileptic Agent. The physiologic effect of oxcarbazepine is by means of Decreased Central Nervous System Disorganized Electrical Activity. | |||
T0765 | Fomepizole | Antizol-Vet,4-Methylpyrazole,Antizol | P450 , CAT , AChR |
Fomepizole (4-Methylpyrazole) is used as an antidote in confirmed or suspected methanol or ethylene glycol poisoning. Fomepizole(4-Methylpyrazole) is a competitive inhibitor of alcohol dehydrogenase, the enzyme that cata... | |||
T22361 | Mepivacaine | Carbocaine | Sodium Channel |
Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by binding to specific voltage-gated sodium channels in nerve ce... | |||
T2078 | Fimepinostat | CUDC-907,PI3K/HDAC Inhibitor,CUDC 907 | Apoptosis , PI3K , HDAC |
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, C... | |||
T6604 | Nepicastat hydrochloride | Nepicastat HCl,RS-25560-197 hydrochloride,SYN-117 hydrochloride,Nepicastat (SYN-117) HCl | Hydroxylase |
Nepicastat hydrochloride (RS-25560-197 hydrochloride) is an effective and specific inhibitor, which is used for bovine and human dopamine-β-hydroxylase with IC50 of 8.5 nM and 9 nM, respectively.The affinity of Nepicasta... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T3S2372 | 7-epi-Taxol | 7-Epitaxol,7-epi-Paclitaxel | Others , Microtubule Associated |
1. 7-epi-Taxol (7-Epitaxol) is the major derivative of taxol found in cells and that its presence does not alter, in a major way, the overall biological activity of taxol. | |||
T13681 | Epi-galantamine | AChE | |
Epi-galantamine, a diastereomer of galantamine, is an alkaloid extracted from the bulbs and flowers of the Caucasian snowdrop (Galanthus woronowii). It acts as an AChE inhibitor, featuring an EC50 of 45.7 μM. | |||
T5738 | 7-Epi 10-desacetyl paclitaxel | 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol | Others |
7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) shows IC50 values of 0.085 nM, against HeLa cells. | |||
TN2755 | 2-Desoxy-4-epi-pulchellin | Anti-infection | |
2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows sig... | |||
T40200 | 5-epi-Jinkoheremol | ||
5-epi-Jinkoheremol exhibits more potent fungicidal activity than validamycin. | |||
TN2368 | 8-Epiloganic acid | 8-Epi-Loganic acid | Others |
8-Epiloganic acid has antibacterial and antiviral effects. | |||
TN3962 | epi-Eudesmol | Others | |
epi-Eudesmol is a natural product from Laggera alata var. montana C. D. Adams. | |||
TN1222 | 26-Deoxyactein | 27-Deoxyactein,23-epi-26-Deoxyactein | NOS , CDK , NO Synthase |
23-epi-26-Deoxyactein (27-Deoxyactein) has anti-inflammatory activity, it inhibits nitric oxide production by reducing iNOS expression without affecting activity of the enzyme. It also has anti-cancer activity, it can in... | |||
TN6388 | Methyl epi-dihydrophaseate | ||
Methyl epi-dihydrophaseate is a natural product for research related to life sciences. The catalog number is TN6388 and the CAS number is 57761-30-5. | |||
TN3025 | 4-Epi-curcumenol | Others | |
4-Epi-curcumenol is a natural product of Curcuma, Zingiberaceae. The catalog number is TN3025 and the CAS number is 350602-21-0. 4-Epi-curcumenol can be used as a reference standard. | |||
TN3026 | 4-Epi-isoinuviscolide | Others | |
4-Epi-isoinuviscolide is a natural product of Inula, Asteraceae. The catalog number is TN3026 and the CAS number is 68832-39-3. 4-Epi-isoinuviscolide can be used as a reference standard. | |||
TN3163 | 6-epi-Albrassitriol | Others | |
6-epi-Albrassitriol is a natural product from A spergillussp. | |||
TN3164 | 6-epi-Augustifolin | Others | |
6-epi-Augustifolin is a natural product for research related to life sciences. The catalog number is TN3164 and the CAS number is 369390-94-3. | |||
TSP-40962761 | 3-epi Caryoptin | ||
3-epi Caryoptin is a useful organic compound for research related to life sciences and the catalog number is TSP-40962761. | |||
TN2756 | 2-Epi-3a-epiburchellin | Others | |
2-Epi-3a-epiburchellin is a natural product for research related to life sciences. The catalog number is TN2756 and the CAS number is 57457-99-5. | |||
TN5972 | 3-epi-Isocucurbitacin B | ||
3-epi-Isocucurbitacin B is a natural product for research related to life sciences. The catalog number is TN5972 and the CAS number is 89647-62-1. | |||
TN5605 | 7-Epi-10-deacetylcephalomannine | ||
7-Epi-10-deacetylcephalomannine is a natural product from Taxus sumatrana. | |||
T39613 | 11-epi-mogroside V | ||
11-epi-mogroside V, a compound found in the fruit of Siraitia grosvenori, possesses significant bioactivity by enhancing glucose uptake in vitro, specifically in human HepG2 cells. | |||
T19882 | Bryonolic acid | UNII-J7YR6A878I,20-epi-Bryonolic acid | Apoptosis , Antioxidant , Calcium Channel |
Bryonolic acid (20-epi-Bryonolic acid), a triterpenoid extracted from Sandoricum indicum, possesses immunomodulatory, anti-inflammatory, antioxidant and anticancer activities and protects PC12 cells from NMDA-induced apo... | |||
TN5394 | 3-epi-Dihydroscandenolide | 15,6-diolide,3β-Acetoxy-1,10-epoxy-4-germacrene-12,8;15,6-diolide,3β-Acetoxy-1,10-epoxy-4-germacrene-12,8 | |
3-epi-Dihydroscandenolide is a natural product for research related to life sciences. The catalog number is TN5394 and the CAS number is 1137951-08-6. | |||
TN3162 | 6-Epi-8-O-acetylharpagide | Others | |
6-Epi-8-O-acetylharpagide is a natural product of Scrophularia, Scrophulariaceae. The catalog number is TN3162 and the CAS number is 97169-44-3. 6-Epi-8-O-acetylharpagide can be used as a reference standard. | |||
TN2597 | 12-Hydroxy-6-epi-albrassitriol | Others | |
12-Hydroxy-6-epi-albrassitriol is a natural product for research related to life sciences. The catalog number is TN2597 and the CAS number is 178330-78-4. | |||
TN3258 | (7R)-Methoxy-8-epi-matairesinol | Others | |
(7R)-Methoxy-8-epi-matairesinol is a natural product for research related to life sciences. The catalog number is TN3258 and the CAS number is 198827-23-5. | |||
TN2895 | 3,5-Dicaffeoyl-epi-quinic acid | IL Receptor , p38 MAPK , TNF , Caspase , JNK , Histamine Receptor | |
3,5-Dicaffeoyl-epi-quinic acid shows anti-inflammatory activity, it may improve mast cell-mediated inflammatory diseases. | |||
TN3224 | 7-Epi-5-eudesmene-1beta,11-diol | Others | |
7-Epi-5-eudesmene-1beta,11-diol is a natural product for research related to life sciences. The catalog number is TN3224 and the CAS number is 87261-77-6. | |||
T83359 | 3-epi-Tilifodiolide | ||
3-epi-Tilifodiolide, a neo-clerodane diterpenoid, can be isolated from the aerial parts of Salvia leucantha. [1] | |||
T75609 | 7-epi-Isogarcinol | ||
7-epi-Isogarcinol, a polycyclic polyprenylated acylphloroglucinol (PPAP), exhibits moderate antiproliferative activity by blocking the STAT3 signaling pathway, thereby inducing apoptosis and inhibiting cell migration [1]... | |||
T74056 | epi-Aszonalenin A | ||
Epi-Aszonalenin A, a benzodiazepine fungal metabolite initially derived from Aspergillus novofumigatus, functions as a psychoactive agent [1]. | |||
T83360 | 3-epi-Padmatin | ||
3-epi-Padmatin, a natural product extractable from Inula graveolens, exhibits potent biological activities [1]. | |||
T83361 | 3-epi-Digitoxigenin | ||
3-epi-Digitoxigenin is a triterpene extracted from the foliage and stems of the Plumeria frangipani. | |||
T83591 | (±)-7-epi-Kadsurenone | ||
(±)-7-epi-Kadsurenone is a novel lignan featuring a hydrobenzofuran structure and a bicyclic [3.2.1]octane moiety. [1] | |||
T83362 | 3-epi-Bufalin | ||
Bufalin (compound 2a) is a microbial transformation product of the bufadienolide [1]. | |||
T78480 | 24-Epicastasterone | 24-epi-Castasterone | |
24-Epicastasterone (24-epi-Castasterone), a naturally occurring brassinosteroid, can be isolated from Hydrodictyon reticulatum [1]. | |||
TN6799 | Epiprogoitrin | epi-Progoitrin | Others |
Epiprogoitrin (epi-Progoitrin) is a epimer that can be deglycosylated to epigoitrin. | |||
T83397 | 23-Epi-26-deoxycimicifugoside | ||
23-Epi-26-deoxycimicifugoside is a triterpene xyloside isolated from Cimicifuga racemosa [1]. | |||
T74133 | 23-epi-26-Deoxyactein | ||
23-epi-26-Deoxyactein is a naturally occurring compound exhibiting anti-obesity and anti-cancer properties when administered orally [1] [2] [3]. | |||
T75453 | 11-epi-Chaetomugilin I | ||
11-epi-Chaetomugilin I, a metabolite identified in Chaetomium globosum, demonstrates notable cytotoxic activity against several cell lines, including the murine P388 and L1210 leukemia cell lines, the human HL-60 leukemi... | |||
T83319 | 4-epi-Withaferin A | ||
4-epi-Withaferin A (compound 28), an analogue of Withaferin A, exhibits enhanced cytotoxicity and cytoprotective heat-shock-inducing activity (HSA). It shows promise for the investigation of protein aggregation-associate... | |||
T17198 | UCN-02 | 7-epi-Hydroxystaurosporine | Others |
UCN-02 is a selective protein kinase C inhibitor produced by Streptomyces strain N-12 (IC50s: 62 nM and 250 nM for PKC and protein kinase A (PKA), respectively). | |||
T81701 | Nardoguaianone K | 10-epi-Nardoguaianone J | |
Nardoguaianone K, a guaiane-type sesquiterpenoid isolated from the roots of Nardostachys chinensis, has potential applications in pancreatic cancer research [1] [2]. | |||
TN1614 | Episyringaresinol | (+)-epi-syringaresinol,ZINC5665087,(+)-Lirioresinol A | Others |
Episyringaresinol ((+)-epi-syringaresinol) is a natural lignan isolated from Kalimeris indica. | |||
T83436 | 18β-Hydroxy-3-epi-α-yohimbine | ||
18β-Hydroxy-3-epi-α-yohimbine, a derivative of yohimbine, is a natural product occurring in Rauvolfia vomitoria [1]. | |||
T79982 | 2'-epi-2'-O-Acetylthevetin B | GHSC-74 | Apoptosis |
2'-Epi-2'-O-Acetylthevetin B (GHSC-74), a cardiac glycoside extractable from Cerbera manghas L. seeds, diminishes cell viability, triggers apoptosis, and disrupts mitochondrial membrane potential in HepG2 cells [1]. | |||
TN6049 | Rauvovertine A | 2055073-71-5,17-epi-Rauvovertine A | |
Rauvovertine A shows cytotoxicity in vitro against human tumor cell lines. | |||
TN2461 | Loganic acid 6′-O-β-D-glucoside | 8-Epi-Loganic acid-6'-O-β-D-glucoside | Others |
Loganic acid 6′-O-β-D-glucoside (8-Epi-Loganic acid-6'-O-β-D-glucoside) is a natural product from Cistanche deserticola and inhibts the production of LPS-induced NO and TNF-α. | |||
T19880 | Friedelinol | Friedelan-3alpha-ol,Friedelan-3-ol,NSC 407041,epi-Friedelinol,Epifriedelanol | |
Friedelinol is a pentacyclic trierpene plant as the free acid or the aglycone for many saponins. Friedelinol can rearrange to the isomer, ursolic acid, or be oxidized to taraxasterol and amyrin. | |||
TN3967 | Epieriocalyxin A | ERK , BCL , ROS , Caspase , DNA/RNA Synthesis , JNK | |
Epieriocalyxin A can suppress Caco-2 colon cancer cell growth. It could be a potential drug for colon cancer therapy in the future. | |||
T2856 | (-)-Epicatechin | L-Epicatechin,Epicatechin,(-)-Epicatechol | Ferroptosis , COX , Endogenous Metabolite |
(-)-Epicatechin (Epicatechin) is an inhibitor of cyclooxygenase-1 (COX-1), inhibiting the IL-1β-induced expression of iNOS by blocking the nuclear localization of the p65 subunit of NF-κB. | |||
TN7121 | D-Epigalbacin | (-)-Zuonin A | JNK |
d-Epigalbacin ((-)-Zuonin A) is a naturally occurring lignin. d-Epigalbacin is a potent, selective JNKs inhibitor, with IC50s of 1.7 μM, 2.9 μM and 1.74 μM for JNK1, JNK2 and JNK3, respectively. | |||
T41017 | Epigambogic acid | ||
Epigambogic acid is a small molecule compound from Garcinia Cambogia with anti-tumor, antitussive, expectorant and anti-inflammatory activities. | |||
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Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01030 | TFPI Protein, Human, Recombinant (His) | Human | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPK-00194 | TFPI Protein, Human, Recombinant (His & Avi) | Human | HEK293 |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPK-00195 | TFPI Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 |
Oestrogens influence the pathophysiology and development of hormone-sensitive cancers, such as breast cancer. Tissue factor pathway inhibitor (TFPI) is a serine protease inhibitor of the extrinsic coagulation pathway and... | |||
TMPY-05179 | TFPI Protein, Human, Recombinant (His), Biotinylated | Human | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPY-00928 | TFPI Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Tissue factor pathway inhibitor (TFPI) is the natural inhibitor of TF coagulant and signaling activities. It is a Kunitz-type serine proteinase inhibitor that down-regulates tissue factor-initiated blood coagulation. Wit... | |||
TMPY-00023 | Epiphycan Protein, Human, Recombinant (His) | Human | HEK293 |
Epiphycan Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 36.1 kDa. Accession number: AAH30958.1 | |||
TMPK-01416 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi), Biotinylated | Human | HEK293 |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPH-03582 | MazF Protein, S. epidermidis, Recombinant (His) | Staphylococcus epidermidis | E. coli |
Toxic component of a type II toxin-antitoxin (TA) system. Ribosome-independent, sequence-specific endoribonuclease that cleaves mRNA, thus inhibiting protein synthesis and inducing bacterial stasis. It cuts between the f... | |||
TMPH-03075 | 3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO) | Oxyuranus microlepidotus | E. coli |
3FTx-Oxy6 Protein, Oxyuranus microlepidotus, Recombinant (His & Myc & SUMO) is expressed in E. coli. | |||
TMPK-01412 | HLA-B*15:01&B2M&SARS-CoV-2 epitope (NQKLIANQF) Monomer Protein, Human, MHC (His & Avi) | Human | HEK293 |
HLA-B*15:01 is strongly associated with asymptomatic infection with SARS-CoV-2 and is likely to be involved in the mechanism underlying early viral clearance. T cells from pre-pandemic individuals carrying HLA-B*15:01 we... | |||
TMPY-02166 | Epiregulin Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncoge... | |||
TMPY-02169 | Epiregulin Protein, Human, Recombinant (hFc) | Human | HEK293 |
Epiregulin (EREG) is a member of the epidermal growth factor family. Epiregulin (EREG) can function as a ligand of EGFR (epidermal growth factor receptor), as well as a ligand of most members of the ERBB (v-erb-b2 oncoge... | |||
TMPH-03583 | Extracellular elastase Protein, S. epidermidis, Recombinant (His & Myc) | Staphylococcus epidermidis | E. coli |
Protease that has a low substrate specificity. Glucagon is preferentially cleaved between aromatic (Phe) and hydrophobic (Val) amino acids. Hydrolyzes casein and elastin. | |||
TMPH-03581 | Dihydrofolate reductase Protein, S. epidermidis, Recombinant (His) | Staphylococcus epidermidis | E. coli |
Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. | |||
TMPH-03584 | Shikimate dehydrogenase Protein, S. epidermidis, Recombinant (His & Myc) | Staphylococcus epidermidis | E. coli |
Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA). It can also u... | |||
TMPH-00398 | PPK2 Protein, Chlorobium tepidum, Recombinant (His & Myc) | Chlorobaculum tepidum | E. coli |
Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). |
Cat No. | Product Name | ||
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L1200 | Epigenetics Compound Library | 953 compounds | |
Well-chosen 953 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs; |