Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by binding to specific voltage-gated sodium channels in nerve cell membranes, inhibiting sodium inward flow and membrane depolarisation. mepivacaine is indicated for nerve blocks and epidurals.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
500 mg | In stock | $ 66.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 73.00 |
Description | Mepivacaine (Carbocaine) is an amide compound for local anaesthesia that causes transient loss of self-consciousness in humans or animals. mepivacaine acts by binding to specific voltage-gated sodium channels in nerve cell membranes, inhibiting sodium inward flow and membrane depolarisation. mepivacaine is indicated for nerve blocks and epidurals. |
In vitro | Mepivacaine exhibits a usage-dependent blockade of Na(v)1.8 channels, while S(-)-bupivacaine shows a preference for TTX-sensitive Na(+) channels.[2] |
In vivo | Intratesticular mepivacaine (10 mL ; injection) when compared with intratesticular lidocaine results in improved cremaster muscle relaxation when only waiting five min prior to the start of the procedure.[2] |
Synonyms | Carbocaine |
Molecular Weight | 246.35 |
Formula | C15H22N2O |
CAS No. | 96-88-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 30.0 mg/mL (121.8 mM ), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Mepivacaine 96-88-8 Membrane transporter/Ion channel Sodium Channel Carbocaine inhibitor inhibit