Search Result

Search Results for " des "

Targets

Stearoyl-CoA Desaturase (SCD) Bradykinin Receptor

308

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
TP1918L1	Lys-[Des-Arg9]Bradykinin acetate	Lys-[Des-Arg9]Bradykinin acetate (71800-36-7 free base)	Bradykinin Receptor
	Lys-[Des-Arg9]Bradykinin acetate is an endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces p...		Bradykinin Receptor
TP1918L	Lys-[Des-Arg9]Bradykinin,TFA	Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa)	Bradykinin Receptor
	Lys-[Des-Arg9]Bradykinin,TFA is Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripher...		Bradykinin Receptor
T1883	Des(benzylpyridyl) Atazanavi		HIV Protease
	The N-dealkylated metabolite (M1) of Atazanavir, a HIV protease inhibitor.		HIV Protease
T8809	[Des-Arg9]-Bradykinin TFA		Bradykinin Receptor
	[Des-Arg9]-Bradykinin is an agonist of Bradykinin (B1) receptor that displays selectivity for B1 over B2 receptors.		Bradykinin Receptor
TP1445	[Des-Arg9]-Bradykinin acetate		Bradykinin Receptor
	[Des-Arg9]-Bradykinin acetate is a selective agonist of Bradykinin B1 receptor.		Bradykinin Receptor
TP1917L1	Sar-[D-Phe8]-des-Arg9-Bradykinin acetate	Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base)	Bradykinin Receptor
	Sar-[D-Phe8]-des-Arg9-Bradykinin acetate is a potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cl...		Bradykinin Receptor
T1216	Diethylstilbestrol	Stilbestrol,DES	Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	Diethylstilbestrol (DES) is used in the treatment of menopausal and postmenopausal disorders.		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T7645	[Des-Arg9]-Bradykinin	[Des-Arg9]-Bradykinin(2TFA)	Bradykinin Receptor
	[Des-Arg9]-Bradykinin ([Des-Arg9]-Bradykinin(2TFA))(2TFA) is an agonist of Bradykinin (B1) receptor.		Bradykinin Receptor
TP2032	des-Gln14-Ghrelin	des-Gln14-Ghrelin (rat)
	An endogenous ligand for the ghrelin receptor (GHS-R1a), produced by alternative splicing of the rat ghrelin gene. Potently induces Ca2+ release in cells expressing ghrelin receptors (EC50 = 2.4 nM) and stimulates GH rel...
TP1181	Bradykinin (2-9)	Des-Arg1-bradykinin	Bradykinin Receptor
	Bradykinin (2-9) (Des-Arg1-bradykinin) is an amino-truncated peptide compound that is a metabolite of Bradykinin. It is formed by the cleavage action of Aminopeptidase P.		Bradykinin Receptor
T36638	[Des-His1,Glu9]-Glucagon amide TFA	[Des-His1,Glu9]-Glucagon amide TFA
	[Des-His1,Glu9]-Glucagon amide TFA is a potent peptide antagonist targeting the glucagon receptor, featuring a pA2 value of 7.2. It holds potential utility in diabetes pathogenesis research[1].
T31634	[Des-Tyr1]-Met-Enkephalin	Met-enkephalin, des-tyr(1),1-De-tyr-met-enkephalin,Enkephalin-met, des-tyr(1)-
	Enkephalin-met, des-tyr(1)- ccauses retrograde amnesia in rats.
TP2033	[Des-His1,Glu9]-Glucagon amide	des-His1-[Glu9]-Glucagon (1-29) amide
	Glucagon receptor antagonist (pA2 = 7.2 for inhibition of glucagon-induced adenylyl cyclase activation in rat liver membranes); displays no agonist activity. Enhances glucose-stimulated pancreatic insulin release in vitr...
TP2450	Argipressin, des-glynh2(9)-	9-Deglycinamide-argipressin,(Arg8,de-Gly9)-vasopressin,DEAVP,DGAVP,9-Des-glynh2-argipressin
	Argipressin, des-glynh2(9)-, can effect on aggregation of blood platelets.
TP1918	Lys-[Des-Arg9]Bradykinin
	Endogenous potent and highly selective bradykinin B1 receptor agonist (Ki values are 0.12 and > 30000 nM at human B1 and B2 receptors respectively). Hypotensive agent that reduces peripheral vascular resistance in vivo. ...
TP2241	[Des-octanoyl]-Ghrelin (human)		Others
	[Des-octanoyl]-Ghrelin (human) is a Non-acylated, major circulating isoform of ghrelin.		Others
TP2242	[Des-octanoyl]-Ghrelin (rat)		Others
	[Des-octanoyl]-Ghrelin (rat) is a Non-acylated, major circulating isoform of ghrelin.		Others
TP1917	Sar-[D-Phe8]-des-Arg9-Bradykinin
	Potent and selective bradykinin B1 receptor agonist (EC50 = 9.02 nM in rabbit aorta) that is resistant to aminopeptidase, kininase I and II (ACE) and neutral endopeptidase cleavage. Exhibits hypotensive and angiogenic ac...
T35602	O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine
	O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine is a major metabolite of the calcium channel inhibitor amlodipine .1 1.Taguchi, R., Naito, T., Sato, H., et al.Validated LC-MS/MS method for the simultaneous determin...
T83500	[Des-Arg10]-HOE I40
	[Des-Arg10]-HOE 140 is a bioactive peptide that functions as a potent B1 bradykinin receptor antagonist.
T75928	des-Gln14-Ghrelin TFA
	Des-Gln14-Ghrelin TFA serves as a potent endogenous ligand for the growth hormone secretagogue receptor, effectively inducing increases in intracellular calcium levels ([Ca2+]i) in CHO-GHSR62 cells with an EC50 of 2.4 nM...
T80394	Des(8-14)brevinin-1PMa
	Des(8-14)brevinin-1PMa is a host-defense peptide known for its potent antimicrobial properties, particularly against Staphylococcus aureus and Echerichia coli. Additionally, this compound demonstrates hemolytic activity ...
T73646	Lys-[Des-Arg9]Bradykinin TFA
	Lys-[Des-Arg9]Bradykinin TFA is a naturally occurring kinin that serves as a potent and highly selective agonist for the bradykinin B1 receptor, demonstrating binding affinities (K i values) of 0.12 nM, 1.7 nM, and 0.23 ...
T76326	[Des-His1,Glu9] Glucagon
	[Des-His1,Glu9] Glucagon, a powerful antagonist of the glucagon receptor system, plays a crucial role in enhancing the glucose-stimulated insulin release from pancreatic islet cells. This compound is utilized in diabetes...
T80072	Des-Arg9-[Leu8]-Bradykinin acetate		Bradykinin Receptor
	Des-Arg9-[Leu8]-Bradykinin acetate is a potent antagonist of the bradykinin receptor 1 (B1R), utilized in renal fibrosis research [1].		Bradykinin Receptor
T80117	Lys-(Des-Arg9,Leu8)-Bradykinin		Bradykinin Receptor
	Lys-(Des-Arg9,Leu8)-Bradykinin is a selective antagonist of the bradykinin B1 receptor [1].		Bradykinin Receptor
T76291	Des His1, Glu8 Exendin-4
	Des His1, Glu8 Exendin-4 is a potent antagonist of the glucagon-like peptide-1 receptor (GLP-1-R), enhancing glucose homeostasis through the dual regulation of insulin secretion and glucose production. This compound is e...
TP2370	Angiotensin pentapeptide	Angiotensin II (4-8),(Des-1,2,3)angiotensin II
	Angiotensin pentapeptide is a peptide.
T83547	(Des-Bromo)-Neuropeptide B (1-23) (human)
	'(Des-Bromo)-Neuropeptide B (1-23) (human)' is an agonist for orphan G-protein-coupled receptors, exhibiting a K i of 1.2 nM for GPR7 (NPBW1) and 341 nM for GPR8 (NPBW2) respectively [1].
T76593	(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
	Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon), a gonadotropin-releasing hormone (GnRH) analog, effectively induces ovulation and/or spawning in farmed fish [1].
T76595	(Des-His6)-ACTH (1-24) (human, bovine, rat)
	(Des-His^6)-ACTH (1-24) (human, bovine, rat) is an adrenocorticotropic hormone (ACTH) analog. Produced by the anterior pituitary gland, ACTH is a polypeptide tropic hormone that regulates the production of cortisol and a...
T76591	(Des-Glu5)-ACTH (1-24) (human, bovine, rat)
	(Des-Glu5)-ACTH (1-24) (human, bovine, rat) is an adrenocorticotropic hormone (ACTH) analogue, synthesized by the anterior pituitary gland to regulate cortisol and androgen production [1]. This polypeptide tropic hormone...
T76601	(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)
	(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14), a bombesin (BBN) antagonist, holds potential for cancer research applications [1].
T76633	(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin
	(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin, a potent vasopressin V1 receptor (VP V1R) antagonist, significantly lowers mean arterial pressure (MAP) in rats [1].
T76590	(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin
	(D(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin, serving as an oxytocin receptor antagonist, effectively nullifies the augmentation of inhibitory postsynaptic currents in CA1 pyramidal neurons by oxytocin [1].
T83688	R 715 TFA	[Ac-Lys-[D-βNal7,Ile8]des-Arg9]-BK,Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D2Nal-Ile-OH
	R 715, a bradykinin B1 receptor antagonist, inhibits contractions in isolated human umbilical cords that express bradykinin B1 receptors (pA2 = 8.49). When administered at doses of 200, 400, and 600 µg/kg, R 715 enhances...
T69630	Diphenyleneiodonium (free base)
	Diphenyleneiodonium (free base) is an NADPH oxidase inhibitor.
T38888	Azide-PEG3-Desthiobiotin	Azide-PEG3-Desthiobiotin
	Azide-PEG3-Desthiobiotin is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
T27084	Crisdesalazine	AAD2004,AAD 2004,AAD-2004	Prostaglandin Receptor
	Crisdesalazine (AAD 2004) is an inhibitor of microsomal prostaglandin E2 synthase-1 (mPGES-1). Crisdesalazine reduces autophagosome formation, axonopathy, and motor neuron degeneration, improving motor function and incre...		Prostaglandin Receptor
T10760	Ceramides Mixture		Telomerase
	Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ...		Telomerase
T16369	O-Desmethyl gefitinib		EGFR
	O-Desmethyl gefitinib inhibits EGFR (IC50: 36 nM in subcellular assays). In human plasma, O-Desmethyl gefitinib is an active metabolite of Gefitinib. The formation of O-desmethyl gefitinib is dependent on the CYP2D6 acti...		EGFR
T65739	Methyl candesartan	Candesartan Methyl Ester	RAAS
	Methyl candesartan (Candesartan Methyl Ester) is a potent angiotensin 2 receptor antagonist used in the study of hypertension.		RAAS
T0537	Desbenzyl Donepezil Hydrochloride		Others
	Desbenzyl Donepezil Hydrochloride is an impurity of Donepezil.		Others
TP2323L	Deslorelin acetate(57773-65-6 free base)	Deslorelin acetate	GNRH Receptor
	Deslorelin acetate(57773-65-6 free base) is a gonadotropin releasing hormone super-agonist (GnRH agonist)		GNRH Receptor
T9128	N-Desmethyltrimipramine		Others
	N-Desmethyltrimipramine is a biochemical.		Others
T19991	N-desmethylmirtazapine	N-Demethylmirtazapine,Normirtazapine,ORG3838,ORG 3838,J1.061.658A,ORG-3838	Others
	N-desmethylmirtazapine (J1.061.658A) is a metabolite of mirtazapine. N-desmethylmirtazapine is also commonly used as an anxiolytic, hypnotic, antiemetic, and appetite stimulant.		Others
T6819	Desogestrel	Org-2969,Desogen,Desogestrelum,Cerazette	Estrogen/progestogen Receptor , Progesterone Receptor
	Desogestrel (Cerazette) is a synthetic progestational hormone used often as the progestogenic component of combined oral contraceptive agents.		Estrogen/progestogen Receptor , Progesterone Receptor
T6364	Desfesoterodine	5-HMT,(R)-5-Hydroxymethyl Tolterodine,PNU-200577,5-HM,5-hydroxymethyl Tolterodine	AChR
	Desfesoterodine (5-HMT) is a new muscarinic receptor antagonist with Kb of 0.84 nM.		AChR
T67849	O-Desethyl Dapagliflozin	Empagliflozin-4	SGLT
	O-Desethyl Dapagliflozin (Empagliflozin-4) is a SGLT2 inhibitor, IC50=33nM.		SGLT
T2400	Candesartan Cilexetil	TCV-116	Apoptosis , RAAS
	Candesartan Cilexetil (TCV-116) is an angiotensin II receptor antagonist (IC50: 0.26 nM). After hydrolysis of candesartan cilexetil to candesartan during gastrointestinal absorption, candesartan selectively competes with...		Apoptosis , RAAS

Compounds

Lys-[Des-Arg9]Bradykinin acetate

TP1918L1

Synonym: Lys-[Des-Arg9]Bradykinin acetate (71800-36-7 free base)

Target: Bradykinin Receptor

Lys-[Des-Arg9]Bradykinin,TFA

TP1918L

Synonym: Lys-[Des-Arg9]Bradykinin,TFA 71800-36-7(fb-tfa)

Target: Bradykinin Receptor

Des(benzylpyridyl) Atazanavi

T1883

Synonym:

Target: HIV Protease

[Des-Arg9]-Bradykinin TFA

T8809

Synonym:

Target: Bradykinin Receptor

[Des-Arg9]-Bradykinin acetate

TP1445

Synonym:

Target: Bradykinin Receptor

Sar-[D-Phe8]-des-Arg9-Bradykinin acetate

TP1917L1

Synonym: Sar-[D-Phe8]-des-Arg9-Bradykinin acetate(126959-88-4 free base)

Target: Bradykinin Receptor

Diethylstilbestrol

T1216

Synonym: Stilbestrol,DES

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor

[Des-Arg9]-Bradykinin

T7645

Synonym: [Des-Arg9]-Bradykinin(2TFA)

Target: Bradykinin Receptor

des-Gln14-Ghrelin

TP2032

Synonym: des-Gln14-Ghrelin (rat)

Target:

Bradykinin (2-9)

TP1181

Synonym: Des-Arg1-bradykinin

Target: Bradykinin Receptor

[Des-His1,Glu9]-Glucagon amide TFA

T36638

Synonym: [Des-His1,Glu9]-Glucagon amide TFA

Target:

[Des-Tyr1]-Met-Enkephalin

T31634

Synonym: Met-enkephalin, des-tyr(1),1-De-tyr-met-enkephalin,Enkephalin-met, des-tyr(1)-

Target:

[Des-His1,Glu9]-Glucagon amide

TP2033

Synonym: des-His1-[Glu9]-Glucagon (1-29) amide

Target:

Argipressin, des-glynh2(9)-

TP2450

Synonym: 9-Deglycinamide-argipressin,(Arg8,de-Gly9)-vasopressin,DEAVP,DGAVP,9-Des-glynh2-argipressin

Target:

Lys-[Des-Arg9]Bradykinin

TP1918

Synonym:

Target:

[Des-octanoyl]-Ghrelin (human)

TP2241

Synonym:

Target: Others

[Des-octanoyl]-Ghrelin (rat)

TP2242

Synonym:

Target: Others

Sar-[D-Phe8]-des-Arg9-Bradykinin

TP1917

Synonym:

Target:

O-Des[2-aminoethyl]-O-carboxymethyl dehydroamlodipine

T35602

Synonym:

Target:

[Des-Arg10]-HOE I40

T83500

Synonym:

Target:

des-Gln14-Ghrelin TFA

T75928

Synonym:

Target:

Des(8-14)brevinin-1PMa

T80394

Synonym:

Target:

Lys-[Des-Arg9]Bradykinin TFA

T73646

Synonym:

Target:

[Des-His1,Glu9] Glucagon

T76326

Synonym:

Target:

Des-Arg9-[Leu8]-Bradykinin acetate

T80072

Synonym:

Target: Bradykinin Receptor

Lys-(Des-Arg9,Leu8)-Bradykinin

T80117

Synonym:

Target: Bradykinin Receptor

Des His1, Glu8 Exendin-4

T76291

Synonym:

Target:

Angiotensin pentapeptide

TP2370

Synonym: Angiotensin II (4-8),(Des-1,2,3)angiotensin II

Target:

(Des-Bromo)-Neuropeptide B (1-23) (human)

T83547

Synonym:

Target:

(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)

T76593

Synonym:

Target:

(Des-His6)-ACTH (1-24) (human, bovine, rat)

T76595

Synonym:

Target:

(Des-Glu5)-ACTH (1-24) (human, bovine, rat)

T76591

Synonym:

Target:

(D-Phe6,Leu-NHEt13,des-Met14)-Bombesin (6-14)

T76601

Synonym:

Target:

(Phenylac1,D-Tyr(Et)2,Lys6,Arg8,des-Gly9)-Vasopressin

T76633

Synonym:

Target:

(d(CH2)51,Tyr(Me)2,Thr4,Orn8,des-Gly-NH29)-Vasotocin

Synonym: [Ac-Lys-[D-βNal7,Ile8]des-Arg9]-BK,Ac-Lys-Arg-Pro-Pro-Gly-Phe-Ser-D2Nal-Ile-OH

Target:

Diphenyleneiodonium (free base)

T69630

Synonym:

Target:

Azide-PEG3-Desthiobiotin

T38888

Synonym: Azide-PEG3-Desthiobiotin

Target:

Crisdesalazine

T27084

Synonym: AAD2004,AAD 2004,AAD-2004

Target: Prostaglandin Receptor

O-Desmethyl gefitinib

Synonym: Candesartan Methyl Ester

Target: RAAS

Desbenzyl Donepezil Hydrochloride

T0537

Synonym:

Target: Others

Deslorelin acetate(57773-65-6 free base)

TP2323L

Synonym: Deslorelin acetate

Target: GNRH Receptor

N-Desmethyltrimipramine

T9128

Synonym:

Target: Others

N-desmethylmirtazapine

T19991

Synonym: N-Demethylmirtazapine,Normirtazapine,ORG3838,ORG 3838,J1.061.658A,ORG-3838

Target: Others

Desogestrel

T6819

Synonym: Org-2969,Desogen,Desogestrelum,Cerazette

Target: Estrogen/progestogen Receptor, Progesterone Receptor

Desfesoterodine

T6364

Synonym: 5-HMT,(R)-5-Hydroxymethyl Tolterodine,PNU-200577,5-HM,5-hydroxymethyl Tolterodine

Target: AChR

O-Desethyl Dapagliflozin

T67849

Synonym: Empagliflozin-4

Target: SGLT

Candesartan Cilexetil

T2400

Synonym: TCV-116

Target: Apoptosis, RAAS

Cat No.	Product Name	Synonyms	Targets
T83300	5′-Des-O-methylharringtonine
	5′-Des-O-methylharringtonine, a natural product, can be isolated from Cephalotaxus harringtonia [1].
TJS0387	Desoxyrhaponticin	Deoxyrhapontin,Deoxyrhaponticin	Apoptosis , Fatty Acid Synthase
	1. Desoxyrhaponticin (Deoxyrhaponticin) is an agent that is potentially effective in controlling postprandial hyperglycemia in diabetes, the in vivo antidiabetic action of this compound can be explained, in part at least...		Apoptosis , Fatty Acid Synthase
T8270	Deserpidine	Harmonyl	RAAS
	Deserpidine (Harmonyl) is only found in individuals that have used or taken this drug. It is an ester alkaloid drug isolated from Rauwolfia canescens (family Apocynaceae) with antipsychotic and antihypertensive propertie...		RAAS
T41078	Lipopolysaccharides, Escherichiacoli	Lipopolysaccharide, E. coli O111:B4	Others
	Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) is a macromolecular component of the outer membrane of Gram-negative bacteria, consisting of three regions: lipid A, oligosaccharide core and O-specific polysacchari...		Others
T3S1265	Liriopesides B	Nolinospiroside F	Others
	Liriopesides B (Nolinospiroside F) exhibited potential anticancer activity against human ovarian cancer A2780 cells.		Others
T3865	Beta-Eudesmol	Beta-Selinenol	TRP/TRPV Channel , AChR
	beta-Eudesmol (Beta-Selinenol) is a noncompetitive antagonist of nicotinic acetylcholine receptors (nAChRs). It is a sesquiterpene that has been found in a variety of plants, including Cannabis, and has diverse biologica...		TRP/TRPV Channel , AChR
TN6786	O-Desmethyl Galanthamine	Sanguinine	AChE
	O-Desmethyl Galanthamine (Sanguinine) is galanthamine-type alkaloid and it is an acetylcholinesterase (AChE) inhibitor, with an IC50 1.83 μM.		AChE
T5738	7-Epi 10-desacetyl paclitaxel	10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol	Others
	7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) shows IC50 values of 0.085 nM, against HeLa cells.		Others
TJS0161	Eudesmol	β-Eudesmol	Others
	β-Eudesmol (β-Eudesmol) is a natural product		Others
T36581	Glucocerebrosides		Others
	Glucocerebrosides is a natural product.		Others
TQ0170	Desacetylcinobufagin	Deacetylcinobufagin	Others
	Desacetylcinobufagin (Deacetylcinobufagin) , a natural product, shows potent activities against Hela and A375 cells in vitro.		Others
TN6930	5-Desmethylsinensetin		Others
	5-Desmethylsinensetin is a natural product.		Others
T22455	Vindesine sulfate	DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS	Others
	Vindesine sulfate (Desacetyl Vinblastine amide) is a vinca alkaloid which is a synthetic derivative of vinblastine, binds to the microtubular proteins of the mitotic spindle, leading to crystallization of the microtubule...		Others
T8183	Deslanoside	Desacetyllanatoside C,Deacetyllanatoside C	ATPase , Drug Metabolite
	Deslanoside (Desacetyllanatoside C) is a rapidly acting cardiac glycoside used to treat congestive heart failure and supraventricular arrhythmias due to reentry mechanisms. Deslanoside inhibits the Na-K-ATPase membrane p...		ATPase , Drug Metabolite
T9358	N,N,O-Tridesmethylvenlafaxine	Tridesmethylvenlafaxine	Others , Endogenous Metabolite
	N,N,O-Tridesmethylvenlafaxine (Tridesmethylvenlafaxine) is a huamn endogenous metabolite.		Others , Endogenous Metabolite
T2520	Desloratadine	Sch34117,NSC 675447	Endogenous Metabolite , Histamine Receptor
	Desloratadine (Sch34117) is a long-acting piperidine derivate with selective H1 antihistaminergic and non-sedating properties. Desloratadine diminishes the typical histaminergic effects on H1-receptors in bronchial smoot...		Endogenous Metabolite , Histamine Receptor
T2862	Desaminotyrosine	Phloretate,3-(4-Hydroxyphenyl)propanoic acid,Hydro-p-coumaric acid,3-(4-Hydroxyphenyl)propionic acid,Phloretic acid	Others , Influenza Virus , Endogenous Metabolite
	Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid) is a microbially associated metabolite. Desaminotyrosine protects from influenza through augmentation of type I interferon signaling.		Others , Influenza Virus , Endogenous Metabolite
T19711	Desmosterol	Desmesterol,24-Dehydrocholesterol	Endogenous Metabolite
	Desmosterol (24-Dehydrocholesterol) is a cholesterol biosynthesis intermediate that inhibits macrophage inflammatory vesicle activation and prevents vascular inflammation and atherosclerosis.		Endogenous Metabolite
T5S0734	Desmethoxyyangonin	Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain	Others , Monoamine Oxidase
	1. Desmethoxyyangonin (5,6-Dehydrokavain) protects LPS or LPS/D-GalN-induced damages in cell or liver tissues mainly through de-regulating IKK/NFκB and Jak2/STAT3 signaling pathways. 2. The induction of CYP3A23 by dihydr...		Others , Monoamine Oxidase
T3836	Eudesmin		MAPK , S6 Kinase
	Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m...		MAPK , S6 Kinase
TN1299	Desmethylglycitein	6,7,4'-Trihydroxyisoflavone	PI3K , CDK , PKC
	Desmethylglycitein (6,7,4'-Trihydroxyisoflavone) , is a novel inhibitor of PKCα in suppressing solar UV-induced matrix metalloproteinase 1, which has antioxidant, and anti-cancer activities.		PI3K , CDK , PKC
T1168	Desonide	Tridesilon,Locapred,Prednacinolone	Glucocorticoid Receptor
	Desonide (Prednacinolone) is a synthetic glucocorticosteroid for topical use, with anti-inflammatory activity. Desonide binds to glucocorticoid receptors in the cytoplasm, and the ligand-receptor complex is translocated ...		Glucocorticoid Receptor
T19259	D-Desthiobiotin		Endogenous Metabolite
	D-Desthiobiotin is a biotin derivative used in affinity chromatography and protein chromatography. It can also be used for protein, cell labeling, detection, and separation.		Endogenous Metabolite
TN2755	2-Desoxy-4-epi-pulchellin		Anti-infection
	2-Desoxy-4-epi-pulchellin has potent in vitro cytotoxicities against the K562, MCF-7, Hela, DU145, U937, H1975, SGC-7901, A549, MOLT-4, and HL60 cell lines with IC50 values ranging from 0.10 to 46.7uM, while it shows sig...		Anti-infection
T11855	Lipopolysaccharides	LPS	Others
	Lipopolysaccharides (LPS) is a natural product, an endotoxin derived from the outer leaflet of the outer membrane of Gram-negative bacteria. Lipopolysaccharides are highly immunogenic antigens that enhance the immune res...		Others
TN5370	1β,10β-Epoxydesacetoxymatricarin
	1beta,10beta-Epoxydesacetoxymatricarin shows high anti-hypercholesterolemic potential.
TN5399	4α,8β-Dihydroxy-3α-(2-hydroxy-3-acetoxy-2-methylbutyryloxy)eudesm-7(11)-en-12,8α-olide
	4α,8β-Dihydroxy-3α-(2-hydroxy-3-acetoxy-2-methylbutyryloxy)eudesm-7(11)-en-12,8α-olide is a natural product for research related to life sciences. The catalog number is TN5399 and the CAS number is 1442989-33-4.
T75650	Rivulariapeptolides 1121
	Rivulariapeptolides 1121 is a potent and selective serine protease inhibitor, demonstrating IC50 values of 35.52 nM for chymotrypsin, 13.24 nM for elastase, and 48.05 nM for proteinase K [1].
TN2668	1beta-Hydroxy-beta-eudesmol		Others
	1beta-Hydroxy-beta-eudesmol is a natural product from Cymbopogon proximus STAPF.		Others
T83386	2-Desoxypleniradin-L-α-arabinopyranoside, 2-acetate
	2-Desoxypleniradin-L-α-arabinopyranoside, 2-acetate, an active compound, can be isolated from Helenium amarum [1].
T37404	O-Desmethylangolensin
	O-Desmethylangolensin is a gut microbiota metabolite of daidzein, a soy isoflavone. It demonstrates antioxidant activity[1][2].
TN3837	Desmethoxycentaureidin		Others
	Desmethoxycentaureidin shows high inhibitory activity against HeLa cell growth (GI50 9 microM).		Others
T21296	Desmopressin acetate trihydrate	Desmogalen,Adiuretin,Deamino Arginine Vasopressin,Vasopressin 1-Desamino-8-arginine
	Desmopressin acetate is a synthetic replacement for vasopressin, which reduces urine production. Medical use of Desmopressin acetate includes: (a) bed wetting; (b) diabetes insipidus; (c) nighttime urination; (d) clottin...
TN2933	3-Eudesmene-1beta,11-diol		Others
	3-Eudesmene-1beta,11-diol is a natural product for research related to life sciences. The catalog number is TN2933 and the CAS number is 658062-22-7.		Others
T83388	2-Desoxyflorilenalin-L-α-arabinopyranoside
	2-Desoxyflorilenalin-L-α-arabinopyranoside, an active compound, can be isolated from Helenium amarum [1].
TN3032	4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one		Others
	4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one is a natural product for research related to life sciences. The catalog number is TN3032 and the CAS number is 133369-42-3.		Others
T68351	Homodestcardin
	Homodestcardin is a cyclic depsipeptide fungal metabolite that has been found in T. roseum and has immunosuppressant activity. It inhibits concanavalin A-induced proliferation of isolated mouse T cells.
TN3839	Desoxo-narchinol A		ERK , IL Receptor , p38 MAPK , TNF , NOS , NF-κB , COX , Prostaglandin Receptor , JNK
	Desoxo-narchinol A exhibits protective effects against LPS-induced endotoxin shock and inflammation through p38 deactivation, it shows inhibitory activity against LPS-induced NO production. Desoxo-narchinol A shows cytot...
TN2495	1,4,7-Eudesmanetriol		Antifection
	1α,4β,7β-Eudesmanetriol and 1β,4β,7β-Eudesmanetriol can inhibit growth of Pseudomonas stutzeri with a MIC value of 117 uM, they also show remarkable activities against acetylcholinesterase enzyme with IC50 values ranging...		Antifection
T81766	Monnierisides A
	Monnierisides A, a chromone glycoside, has been isolated from Cnidium monnieri [1].
TN4030	Eudesm-4(15)-ene-3alpha,11-diol
	Eudesm-4(15)-ene-3alpha,11-diol is a compound derived from Eudesm-4(15)-ene-3alpha,11-diol.
T82578	Desacetylxanthanol
	Desacetylxanthanol (Compound 4), a sesquiterpenoid originating from Xanthium strumarium, exhibits anti-tumor necrosis factor-associated apoptosis-inducing ligand (TRAIL) activity [1].
T11009	Destruxin B		Others
	Destruxin B is a cyclic peptide with insecticidal and anticancer activity isolated from the insect pathogenic fungus Metarhizium isopliae. Destruxin B induces apoptosis of human non-small cell lung cancer cells through t...		Others
T40627	Trichodesmine
	Trichodesmine, a dehydropyrrolizidine alkaloid, exhibits hepatotoxic, pneumotoxic, and neurotoxic effects in vivo.
TN3224	7-Epi-5-eudesmene-1beta,11-diol		Others
	7-Epi-5-eudesmene-1beta,11-diol is a natural product for research related to life sciences. The catalog number is TN3224 and the CAS number is 87261-77-6.		Others
TN6382	Desacetylripariochromene B
	Desacetylripariochromene B is a natural product for research related to life sciences. The catalog number is TN6382 and the CAS number is 69790-24-5.
TN1573	Desmethylxanthohumol		Others
	Desmethylxanthohumol shows estrogenic activity.		Others
T75648	Rivulariapeptolides 1155
	Rivulariapeptolides 1155 is a potent serine protease inhibitor, exhibiting inhibitory concentrations (IC50s) of 41.84 nM, 4.94 nM, and 56.54 nM against chymotrypsin, elastase, and proteinase K, respectively [1].
T83431	1-Desmethylobtusin
	1-Desmethylobtusin, an anthraquinone derivative, is isolatable from Cassia obtusifolia L. [1].
TN3962	Epi-Eudesmol		Others
	epi-Eudesmol is a natural product from Laggera alata var. montana C. D. Adams.		Others
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Natural Products

5′-Des-O-methylharringtonine

Synonym: Deoxyrhapontin,Deoxyrhaponticin

Target: Apoptosis, Fatty Acid Synthase

Lipopolysaccharides, Escherichiacoli

T41078

Synonym: Lipopolysaccharide, E. coli O111:B4

Target: Others

Liriopesides B

T3S1265

Synonym: Nolinospiroside F

Target: Others

beta-Eudesmol

T3865

Synonym: Beta-Selinenol

Target: TRP/TRPV Channel, AChR

O-Desmethyl Galanthamine

TN6786

Synonym: Sanguinine

Target: AChE

7-Epi 10-desacetyl paclitaxel

T5738

Synonym: 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol

Desacetylcinobufagin

TQ0170

Synonym: Deacetylcinobufagin

Target: Others

5-Desmethylsinensetin

Synonym: DVA,Desacetylvinblastine amide,DAVA,Desacetyl Vinblastine amide,VDS

Target: Others

Deslanoside

T8183

Synonym: Desacetyllanatoside C,Deacetyllanatoside C

Target: ATPase, Drug Metabolite

N,N,O-Tridesmethylvenlafaxine

T9358

Synonym: Tridesmethylvenlafaxine

Target: Others, Endogenous Metabolite

Desloratadine

T2520

Synonym: Sch34117,NSC 675447

Target: Endogenous Metabolite, Histamine Receptor

Desaminotyrosine

T2862

Synonym: Phloretate,3-(4-Hydroxyphenyl)propanoic acid,Hydro-p-coumaric acid,3-(4-Hydroxyphenyl)propionic acid,Phloretic acid

Target: Others, Influenza Virus, Endogenous Metabolite

Desmosterol

T19711

Synonym: Desmesterol,24-Dehydrocholesterol

Target: Endogenous Metabolite

Desmethoxyyangonin

T5S0734

Synonym: Desmethoxy yangonin,Demethoxyyangonin,5,6-Dehydrokavain

Target: Others, Monoamine Oxidase

Eudesmin

T3836

Synonym:

Target: MAPK, S6 Kinase

Desmethylglycitein

TN1299

Synonym: 6,7,4'-Trihydroxyisoflavone

Target: PI3K, CDK, PKC

Desonide

T1168

Synonym: Tridesilon,Locapred,Prednacinolone

Target: Glucocorticoid Receptor

D-Desthiobiotin

T19259

Synonym:

Target: Endogenous Metabolite

2-Desoxy-4-epi-pulchellin

TN2755

Synonym:

Target: Anti-infection

1β,10β-Epoxydesacetoxymatricarin

TN5370

Synonym:

Target:

4α,8β-Dihydroxy-3α-(2-hydroxy-3-acetoxy-2-methylbutyryloxy)eudesm-7(11)-en-12,8α-olide

TN5399

Synonym:

Target:

Rivulariapeptolides 1121

T75650

Synonym:

Target:

1beta-Hydroxy-beta-eudesmol

TN2668

Synonym:

Target: Others

2-Desoxypleniradin-L-α-arabinopyranoside, 2-acetate

T83386

Synonym:

Target:

O-Desmethylangolensin

T37404

Synonym:

Target:

Desmethoxycentaureidin

TN3837

Synonym:

Target: Others

Desmopressin acetate trihydrate

T21296

Synonym: Desmogalen,Adiuretin,Deamino Arginine Vasopressin,Vasopressin 1-Desamino-8-arginine

Target:

3-Eudesmene-1beta,11-diol

TN2933

Synonym:

Target: Others

2-Desoxyflorilenalin-L-α-arabinopyranoside

T83388

Synonym:

Target:

4-Hydroxy-11,12,13-trinor-5-eudesmen-7-one

Target: ERK, IL Receptor, p38 MAPK, TNF, NOS, NF-κB, COX, Prostaglandin Receptor, JNK

Eudesm-4(15)-ene-3alpha,11-diol

7-Epi-5-eudesmene-1beta,11-diol

TN3224

Synonym:

Target: Others

Desacetylripariochromene B

TN6382

Synonym:

Target:

Desmethylxanthohumol

TN1573

Synonym:

Target: Others

Rivulariapeptolides 1155

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Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPJ-00882	Desmin Protein, Human, Recombinant (His)	Human	E. coli
	Desmin is a cytoplasmic protein and belongs to the intermediate filament family. interacts with DST and MTM1. Desmin is only expressed in vertebrates, however homologous proteins are found in many organisms. Desmin is th...
TMPY-04960	Der p 1 Protein, Dermatophagoides pteronyssinus, Recombinant (His)	Dermatophagoides pteronyssinus	HEK293 Cells
	Der p 1 Protein, Dermatophagoides pteronyssinus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.7 kDa and the accession number is P08176.
TMPH-00472	Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His & Myc)	Dermatophagoides pteronyssinus	E. coli
	Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His & Myc) is expressed in E. coli.
TMPY-06023	IdeS Protein, Streptococcus pyogenes, Recombinant (His)	Streptococcus pyogenes	E. coli
	IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic...
TMPY-05078	Der f 2 Protein, Dermatophagoides farinae, Recombinant (His)	Dermatophagoides farinae	E. coli
	Der f 2 Protein, Dermatophagoides farinae, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 15 kDa and the accession number is Q00855.1.
TMPY-05518	Der p 5 Protein, Dermatophagoides pteronyssinus, Recombinant (His)	Dermatophagoides pteronyssinus	E. coli
	Der p 5 Protein, Dermatophagoides pteronyssinus, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 16.6 kDa and the accession number is A0A6P6Y2A6.
TMPH-00189	HtpG Protein, Bacteroides fragilis, Recombinant (His & Myc & SUMO)	Bacteroides fragilis	E. coli
	Molecular chaperone. Has ATPase activity. HtpG Protein, Bacteroides fragilis, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 5...
TMPH-00188	BioAB Protein, Bacteroides fragilis, Recombinant (His & Myc)	Bacteroides fragilis	E. coli
	Catalyzes two activities which are involved in the biotine biosynthesis: the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism, and the transfer ...
TMPY-05710	Der p 23 Protein, Dermatophagoides pteronyssinus, Recombinant (His)	Dermatophagoides pteronyssinus	HEK293 Cells
	Der p 23 is a new major allergen of D. pteronyssinus. The house dust mite (HDM) Dermatophagoides pteronyssinus is one of most important allergen sources and a major elicitor of allergic asthma. Der p 23 may be an essenti...
TMPH-00190	Fragilysin Protein, Bacteroides fragilis, Recombinant (His)	Bacteroides fragilis	E. coli
	Diarrheal toxin that hydrolyzes gelatin, azocoll, actin, tropomyosin, and fibrinogen. Fragilysin Protein, Bacteroides fragilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted ...
TMPH-02407	Peroxidase Protein, Lentinula edodes, Recombinant (His & Myc)	Lentinula edodes	E. coli
	Peroxidase Protein, Lentinula edodes, Recombinant (His & Myc) is expressed in E. coli.
TMPH-02363	TROSPA Protein, Ixodes scapularis, Recombinant (His)	Ixodes scapularis	Baculovirus Insect Cells
	Serves as a receptor for ospA protein of B.burgdorferi, the Lyme disease agent. Required for spirochetal colonization. Essential for pathogen adherence to the vector. TROSPA Protein, Ixodes scapularis, Recombinant (His) ...
TMPY-04945	Der p 2 Protein, Dermatophagoides pteronyssinus, Recombinant (His)	Dermatophagoides pteronyssinus	E. coli
	Hypersensitivity to house dust mite (Dermatophagoides sp.) allergens is one of the most common allergic reactions in the world. The house dust mite allergen, Der p 2, is a major allergen and 80–90% of patients who react ...
TMPH-00474	Der p 6 Protein, Dermatophagoides pteronyssinus, Recombinant (GST)	Dermatophagoides pteronyssinus	E. coli
	Der p 6 Protein, Dermatophagoides pteronyssinus, Recombinant (GST) is expressed in E. coli.
TMPY-01892	Desmocollin 2/DSC2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Desmocollin 2/DSC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 75 kDa and the accession number is Q02487-1.
TMPY-06975	Der p 21 Protein, Dermatophagoides pteronyssinus, Recombinant	Dermatophagoides pteronyssinus	E. coli
	Der p 21 Protein, Dermatophagoides pteronyssinus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.55 kDa.
TMPH-00359	AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc)	Caulobacter vibrioides	E. coli
	AlkB Protein, Caulobacter vibrioides, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 31.2 kDa and the accession number is B8GWW6.
TMPY-04642	Desmocollin 2/DSC2 Protein, Rat, Recombinant (hFc)	Rat	HEK293 Cells
	Desmocollin 2/DSC2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101.6 kDa and the accession number is Q3T1K6.
TMPH-00361	Beta-mammal toxin Cn2 Protein, Centruroides noxius, Recombinant (His)	Centruroides noxius	P. pastoris (Yeast)
	Mammal beta-toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the activation voltage to more negative potentials. This toxin is active against mammals. Beta-mammal toxin Cn2 Protein, Centruro...
TMPY-05903	Influenza A H5N1 (A/Bangladesh/207095/2008) Hemagglutinin/HA Protein (His)	H5N1	HEK293 Cells
	Influenza A H5N1 (A/Bangladesh/207095/2008) Hemagglutinin/HA Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.7 kDa.
TMPY-03370	Desmocollin 2/DSC2 Protein, Rat, Recombinant (His)	Rat	HEK293 Cells
	Desmocollin 2/DSC2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 76.1 kDa and the accession number is Q3T1K6.
TMPH-00475	DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His)	Desulfotalea psychrophila	E. coli
	DNA ligase Protein, Desulfotalea psychrophila, Recombinant (His) is expressed in E. coli.
TMPK-00967	DSG-2/Desmoglein-2 Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells...
TMPK-00736	DSG-2/Desmoglein-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293 Cells
	Desmoglein-2 (DSG-2) as the primary high-affinity receptor used by adenoviruses Ad3, Ad7, Ad11 and Ad14. These serotypes represent key human pathogens causing respiratory and urinary tract infections. In epithelial cells...
TMPH-00473	Der p 3 Protein, Dermatophagoides pteronyssinus, Recombinant (His)	Dermatophagoides pteronyssinus	E. coli
	Der p 3 Protein, Dermatophagoides pteronyssinus, Recombinant (His) is expressed in E. coli.
TMPY-05140	Der f 1 Protein, Dermatophagoides farinae, Recombinant (His)	Dermatophagoides farinae	HEK293 Cells
	Der f 1 Protein, Dermatophagoides farinae, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 35.9 kDa and the accession number is Q58A71.
TMPY-06179	IdeS Protein, Streptococcus pyogenes, Recombinant (His & GST)	Streptococcus pyogenes	E. coli
	IdeS (IgG-degrading enzyme of Streptococcus pyogenes) is a secreted cysteine endopeptidase from the human pathogen S. pyogenes with an extraordinarily high degree of substrate specificity, catalyzing a single proteolytic...
TMPH-02408	SPI Protein, Lentinula edodes, Recombinant (His)	Lentinula edodes	E. coli
	Serine protease inhibitor. Active against beta-trypsin and alpha-chymotrypsin with dissociation constants of 0.35 nM and 40 nM respectively. Inhibits factor XIa, but not other enzymes involved in coagulation and fibrinol...
TMPH-00362	Beta-mammal toxin Css4 Protein, Centruroides suffusus, Recombinant (His & SUMO)	Centruroides suffusus	E. coli
	Beta toxins bind voltage-independently at site-4 of sodium channels (Nav) and shift the voltage of activation toward more negative potentials thereby affecting sodium channel activation and promoting spontaneous and repe...
TMPH-00403	Toxin A Protein, Clostridioides difficile, Recombinant (His)	Clostridioides difficile	E. coli
	Toxin A Protein, Clostridioides difficile, Recombinant (His) is expressed in E. coli.
TMPY-05139	Der p 10 Protein, Dermatophagoides pteronyssinus, Recombinant	Dermatophagoides pteronyssinus	E. coli
	Der p 10 Protein, Dermatophagoides pteronyssinus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 32.9 kDa and the accession number is O18416.1.
TMPJ-00964	PRCP Protein, Human, Recombinant (His)	Human	HEK293 Cells
	Lysosomal Pro-X Carboxypeptidase (PRCP) belongs to the peptidase S28 family. PRCP is detected in many tissues, with highest levels observed in placenta, lung, and liver. It is also present in the heart, brain, pancreas, ...
TMPY-02132	LYPLA2 Protein, Human, Recombinant (His)	Human	E. coli
	Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from...