Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Desmethylxanthohumol shows estrogenic activity.
Description | Desmethylxanthohumol shows estrogenic activity. |
In vitro | The present study examines the dynamics of the hop prenylphenol, Desmethylxanthohumol (DMX), by means of quantitative 1H-NMR (qHNMR) in a setting that mimics in vitro and physiological conditions. The experiments provide a comprehensive, time-resolved, and mechanistic picture of the spontaneous isomerization of DMX into congeneric flavanones, including their 1H/2D isotopomers. Formation of the potent phytoestrogen, 8-prenylnaringenin (8PN), suggests that measurable estrogenic activity even of high-purity DMX is an artifact. Together with previously established qHNMR assays including purity activity relationships (PARs), dynamic qHNMR assays complement important steps of the post-isolation evaluation of natural products. |
Source |
Molecular Weight | 340.37 |
Formula | C20H20O5 |
CAS No. | 115063-39-3 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Desmethylxanthohumol 115063-39-3 Others inhibitor inhibit