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Search Result

Search Results for " mec "

Targets

SARS-CoV Parasite

73

Compounds

11

Natural Products

7

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T21727 Ivermectin B1a SARS-CoV , Parasite
Ivermectin B1a is the major (80%) component of commercially available ivermectin and a derivative of Avermectin B1a.
T15212 Emamectin Benzoate MK-244 Apoptosis , Reactive Oxygen Species , GABA Receptor , Parasite
Emamectin Benzoate (MK-244), by binding gamma-aminobutyric acid (GABA) receptor and glutamate-gated chloride channels disrupting nerve signals within arthropods, acts as a chloride channel activator.
T5836 Eprinomectin MK-397 Parasite
Eprinomectin (MK-397) is an avermectin with anthelmintic and insecticidal activities.
T1110 Meclizine dihydrochloride Meclozine dihydrochloride,NSC28728,Meclizine 2HCl Apoptosis , Histamine Receptor
Meclizine dihydrochloride (NSC28728) is a histamine H1 antagonist used in the treatment of motion sickness, vertigo, and nausea during pregnancy and radiation sickness.
T16034 Meclinertant SR 48692 Others
Meclinertant is an effective, selective, nonpeptide, and orally active neurotensin receptor 1 (NTS1) antagonist. Meclinertant competitively antagonizes neurotensin-induced intracellular Ca2+ mobilization (pA2 : 8.13), in...
T21369 Mecillinam Amdinocillin,Mecillinamum,Hexacillin,Coactin,Penicillin HX Antibacterial
Mecillinam (Hexacillin), an extended-spectrum penicillin antibiotic, is considered to be active against Gram-negative bacteria by binding specifically to penicillin-binding protein 2 (PBP2). It is used primarily to treat...
T4345 CeMMEC1 CeMMEC1 HCl Epigenetic Reader Domain , Carboxypeptidase , DNA/RNA Synthesis
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
T2141 Mecamylamine hydrochloride Inversine,Mevasin AChR
Mecamylamine hydrochloride (Mevasin) is a nicotinic antagonist, used as a ganglionic blocker in hypertension.
T0260 Meclofenamic acid sodium Meclofenamate Sodium,Movens,Meclomen,Meclonax Gap Junction Protein , COX
Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.
T2006 Omecamtiv mecarbil CK-1827452 ATPase , Myosin
Omecamtiv mecarbil (CK-1827452) has been used in trials studying the treatment and basic science of Heart Failure, Echocardiogram, Pharmacokinetics, Chronic Heart Failure, and History of Chronic Heart Failure, among othe...
T7560 Pivmecillinam hydrochloride FL-1039 hydrochloride Antibacterial , Antibiotic
Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active prodrug of mecillinam, an extended-spectrum penicillin antibiotic,and is active against gram-negative organisms and used as for amdinocillin.
T4059 Selamectin UK-124114 Chloride channel , P-gp , Parasite
Selamectin (UK-124114) is a macrocyclic lactone derivative of ivermectin, an anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes. In an H. contortus larval development assay, sel...
T40652 Meclizine Meclozine Histamine Receptor
Meclizine, also known as Meclozine, is a piperazine class H1 antagonist with antihistamine properties that inhibits the interaction of histamine at H1 receptors reversibly. It serves as an effective anti-motion sickness ...
T2648 Pimecrolimus SDZ-ASM 981,ASM 981 Others
Pimecrolimus (SDZ-ASM 981), a calcineurin inhibitor immunosuppressant, binds to the receptor macrophilin-12 (FKBP-12) forming a complex that blocks the calcium-dependent signal transduction cascade mediated by calcineuri...
T22489 2'-MeCCPA 2-Chloro-N-cyclopentyl-2′-C-methyladenosine HCV Protease , Adenosine Receptor
2'-MeCCPA is a potent and highly selective A1 adenosine receptor (A1AR) agonist with a K-value of 1.8 nM for AR.2'-MeCCPA inhibits trichostatin-stimulated adenylate cyclase activity with an IC value of 13.1 nM.2'-MeCCPA ...
T67758 Pumecitinib JAK
Pumecitinib is a Janus kinase (JAK) inhibitor. Pumecitinib exhibits anti-inflammatory activity.
T60055 Chromeceptin 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile Akt , IGF-1R , mTOR
Chromeceptin is an inhibitor of the IGF signaling pathway, decreases the numbers of tumorsphere, and inhibits the AKT/mTOR pathway.
T4997 Umeclidinium bromide GSK573719A AChR
Umeclidinium bromide (GSK573719A) is a novel mAChR antagonist.
T7213 Demecarium bromide BC-48 AChE
Demecarium bromide (BC-48) is a potent cholinesterase inhibitor,and is treatment glaucoma agent.
T6801 CeMMEC13 Carboxypeptidase , DNA/RNA Synthesis
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
T7605 Avermectin B1a Abamectin B1a,Avamectin B1a Antibiotic , Parasite
Avermectin B1a is a macrocyclic lactone disaccharide anthelmintic agent .
T0013 Mecarbinate Dimecarbine,Dimecarbin HCV Protease
Mecarbinate (Dimecarbin) is arbidol hydrochloride's chemical intermediate.
T1401 Meclofenoxate hydrochloride Meclofenoxate (Centrophenoxine) HCl,Lucidril,Cerutil,Meclofenoxate HCl Lipoxygenase , COX , AChR , iGluR
Meclofenoxate hydrochloride (Lucidril) is an ester of DIMETHYLAMINOETHANOL and para-chlorophenoxyacetic acid. It has been shown to improve memory and general cognition, and mentally stimulating effect.
T1400L Demeclocycline Ledermycin,Bioterciclin,Deteclo,Declostatin,Deganol Antibacterial
Demeclocycline (Declostatin) is a tetracycline antibiotic produced by a strain of Streptomyces aureofaciens.Demeclocycline has antimicrobial activity and inhibits the action of vasopressin on the renal tubules, leading t...
T22874 Ivermectin B1a-d2 Others
Deuterated ivermectin B1a
T31893 Furmecyclox BAS 389,BAS-389,BAS 389F,BAS389,GUS 215
Furmecyclox is a biochemical.
T29960 Pivmecillinam Amdinocillin pivoxil
Amdinocillin pivoxil is a Pivaloyloxymethyl ester of amdinocillin that is well absorbed orally, but broken down to amdinocillin in the intestinal mucosa. It is active against gram-negative organisms and used as for amdin...
T73702 Mecasermin
Mecasermin (Human IGF-I; FK 780), a recombinant form of human insulin-like growth factor I (IGF-I), holds promise for investigating growth failure attributed to growth hormone (GH) insensitivity, which may be due to defe...
T14082 AB-MECA Others
AB-MECA is a high affinity A3 adenosine receptor agonist. It has high affinity for recombinant A1 and A3 receptors.
T72292 Tilpisertib fosmecarbil
Tilpisertib fosmecarbil is a potent inhibitor of serine/threonine kinases with anti-inflammatory properties.
T70250 Demeclocycline calcium
Demeclocycline calcium is a semisynthetic tetracycline antibiotic which was derived from a strain of Streptomyces aureofaciens. Demeclocycline binds to bacterial 30S ribosomal subunit and prevents binding of aminoacyl-tR...
T69019 Mecamylamine
Mecamylamine, an orally active, nonselective, noncompetitive antagonist of nAChR (nicotinic acetylcholine receptors), exhibits ganglionic blockade capabilities and can cross the blood-brain barrier. Its applications span...
T20632 Mecoprop Mepro,Morogal,Mecprop,Methoxone,Mecoturf
Mecoprop is an herbicide used to control broadleaf weeds.
T31815 Flumecinol Zyxorin
Flumecinol is a hepatic enzyme (cytochrome P-450 monooxygenases) inducer.
T24881 Thymectacin NB 1011,NB-1011,NB1011
Thymectacin is a small molecule phosphoramidite derivative of (E)-5-(2-bromovinyl)-2'-deoxyuridine with potential antineoplastic activity.
T125077 Mecambridine
Mecambridine is a useful organic compound for research related to life sciences and the catalog number is T125077.
T35733 Doramectin aglycone
Doramectin aglycone is an acid degradation product of doramectin , a disaccharide-containing anthelmintic that potentiates glutamate- and GABA-gated chloride channel opening in nematodes, and its acid-catalyzed hydrolysi...
T20164 Lymecycline Limeciclina,Mucomycin,Tetralisal
Lymecycline is a semisynthetic antibiotic. It is related to TETRACYCLINE.
T32016 Guamecycline Guamecyclinum,Guameciclina
Guamecycline is a biochemical.
T35755 Avermectin B1a aglycone
Avermectin B1a aglycone is an aglycone form of the anthelmintic and insecticide avermectin B1a . It hyperpolarizes P. crassipes muscle fibers with a minimum active concentration (MAC) value of 0.1 μM. Avermectin B1a agly...
T37748 Ivermectin B1b
Ivermectin B1b is the minor component . It produces antiparasitic activity by binding to glutamate-gated chloride channels expressed on nematode neurons and pharyngeal muscle cells, inducing irreversible channel opening ...
T11990 Meclofenamic acid Meclofenamate Others , Gap Junction Protein
Meclofenamic acid (Meclofenamate) is a non-selective gap-junction blocker and a selective fat mass and obesity-associated (FTO) enzyme inhibitor. Meclofenamic acid has anti-inflammatory activities.
T31401 S-(+)-Mecamylamine hydrochloride NIH-11008,TC-5214,Dexmecamylamine HCl,NIH11008,TC 5214,NIH 11008,TC5214
Dexmecamylamine( TC-5214, NIH-11008) is used as a nicotinic channel modulator with antidepressant activity.
T69834 Tivumecirnon FLX475
Tivumecirnon (FLX475) is a potent antagonist of CCR4, effectively inhibiting regulatory T cells that hinder antitumor immune responses, thereby demonstrating antitumor activity.
T74063 MeCY5-NHS ester triethylamine
MeCY5-NHS ester (potassium) is a reactive dye optimized for labeling proteins and nucleic acids [1].
T77799 CeMMEC1 HCl
CeMMEC1 is a compound derived from N-methylisoquinolinone that inhibits the second bromodomain of TAF1.
T71873 Temechine hydrobromide
Temechine hydrobromide is used for the identification of new diterpenoidal alkaloid leads as tyrosinase inhibitors.
T71903 Meclocycline
Meclocycline is a tetracycline antibiotic with broad antimicrobial activity. Meclocycline inhibits lactate dehydrogenase (LDH) release and cell toxicity induced by expression of htt-N63-148Q, a mutant form of the hunting...
T24442 Mecrylate
Mecrylate polymerizes in contact with moisture. It is used as a tissue adhesive. It also has higher homologs have hemostatic and antibacterial properties.
TNU1266 DMT-locMeC(bz) phosphoramidite
Nucleoside Derivatives - LNA-related nucleosides; Nucleoside Phorphoramidites

Compounds

Ivermectin B1a
T21727
Synonym:
Target: SARS-CoV, Parasite
Emamectin Benzoate
T15212
Synonym: MK-244
Target: Apoptosis, Reactive Oxygen Species, GABA Receptor, Parasite
Eprinomectin
T5836
Synonym: MK-397
Target: Parasite
Meclizine dihydrochloride
T1110
Synonym: Meclozine dihydrochloride,NSC28728,Meclizine 2HCl
Target: Apoptosis, Histamine Receptor
Meclinertant
T16034
Synonym: SR 48692
Target: Others
Mecillinam
T21369
Synonym: Amdinocillin,Mecillinamum,Hexacillin,Coactin,Penicillin HX
Target: Antibacterial
CeMMEC1
T4345
Synonym: CeMMEC1 HCl
Target: Epigenetic Reader Domain, Carboxypeptidase, DNA/RNA Synthesis
Mecamylamine hydrochloride
T2141
Synonym: Inversine,Mevasin
Target: AChR
Meclofenamic acid sodium
T0260
Synonym: Meclofenamate Sodium,Movens,Meclomen,Meclonax
Target: Gap Junction Protein, COX
Omecamtiv mecarbil
T2006
Synonym: CK-1827452
Target: ATPase, Myosin
Pivmecillinam hydrochloride
T7560
Synonym: FL-1039 hydrochloride
Target: Antibacterial, Antibiotic
Selamectin
T4059
Synonym: UK-124114
Target: Chloride channel, P-gp, Parasite
Meclizine
T40652
Synonym: Meclozine
Target: Histamine Receptor
Pimecrolimus
T2648
Synonym: SDZ-ASM 981,ASM 981
Target: Others
2'-MeCCPA
T22489
Synonym: 2-Chloro-N-cyclopentyl-2′-C-methyladenosine
Target: HCV Protease, Adenosine Receptor
Pumecitinib
T67758
Synonym:
Target: JAK
Chromeceptin
T60055
Synonym: 2-amino-7-(dimethylamino)-4-[3-(trifluoromethyl)phenyl]-4H-chromene-3-carbonitrile
Target: Akt, IGF-1R, mTOR
Umeclidinium bromide
T4997
Synonym: GSK573719A
Target: AChR
Demecarium bromide
T7213
Synonym: BC-48
Target: AChE
CeMMEC13
T6801
Synonym:
Target: Carboxypeptidase, DNA/RNA Synthesis
Avermectin B1a
T7605
Synonym: Abamectin B1a,Avamectin B1a
Target: Antibiotic, Parasite
Mecarbinate
T0013
Synonym: Dimecarbine,Dimecarbin
Target: HCV Protease
Meclofenoxate hydrochloride
T1401
Synonym: Meclofenoxate (Centrophenoxine) HCl,Lucidril,Cerutil,Meclofenoxate HCl
Target: Lipoxygenase, COX, AChR, iGluR
Demeclocycline
T1400L
Synonym: Ledermycin,Bioterciclin,Deteclo,Declostatin,Deganol
Target: Antibacterial
Ivermectin B1a-d2
T22874
Synonym:
Target: Others
Furmecyclox
T31893
Synonym: BAS 389,BAS-389,BAS 389F,BAS389,GUS 215
Target:
Pivmecillinam
T29960
Synonym: Amdinocillin pivoxil
Target:
Mecasermin
T73702
Synonym:
Target:
AB-MECA
T14082
Synonym:
Target: Others
Tilpisertib fosmecarbil
T72292
Synonym:
Target:
Demeclocycline calcium
T70250
Synonym:
Target:
Mecamylamine
T69019
Synonym:
Target:
Mecoprop
T20632
Synonym: Mepro,Morogal,Mecprop,Methoxone,Mecoturf
Target:
Flumecinol
T31815
Synonym: Zyxorin
Target:
Thymectacin
T24881
Synonym: NB 1011,NB-1011,NB1011
Target:
Mecambridine
T125077
Synonym:
Target:
Doramectin aglycone
T35733
Synonym:
Target:
Lymecycline
T20164
Synonym: Limeciclina,Mucomycin,Tetralisal
Target:
Guamecycline
T32016
Synonym: Guamecyclinum,Guameciclina
Target:
Avermectin B1a aglycone
T35755
Synonym:
Target:
Ivermectin B1b
T37748
Synonym:
Target:
Meclofenamic acid
T11990
Synonym: Meclofenamate
Target: Others, Gap Junction Protein
S-(+)-Mecamylamine hydrochloride
T31401
Synonym: NIH-11008,TC-5214,Dexmecamylamine HCl,NIH11008,TC 5214,NIH 11008,TC5214
Target:
Tivumecirnon
T69834
Synonym: FLX475
Target:
MeCY5-NHS ester triethylamine
T74063
Synonym:
Target:
CeMMEC1 HCl
T77799
Synonym:
Target:
Temechine hydrobromide
T71873
Synonym:
Target:
Meclocycline
T71903
Synonym:
Target:
Mecrylate
T24442
Synonym:
Target:
DMT-locMeC(bz) phosphoramidite
TNU1266
Synonym:
Target:
1 2
Cat No. Product Name Synonyms Targets
TL0015 Pyromeconic acid 3-hydroxy-4H-pyran-4-one Anti-infection
Pyromeconic acid (3-hydroxy-4H-pyran-4-one) and derivatives thereof are potent inhibitors of endonuclease
T1400 Demeclocycline hydrochloride Declomycin,Clortetrin,Detravis,Demeclocycline HCl ribosome , Antibacterial , Antibiotic
Demeclocycline hydrochloride (Declomycin) is a TETRACYCLINE analog having a 7-chloro and a 6-methyl. Because it is excreted more slowly than TETRACYCLINE, it maintains effective blood levels for longer periods of time.
T1131 Ivermectin MK-933 Mitophagy , GluCls , P2X Receptor , SARS-CoV , HIV Protease , Antibiotic , Parasite , Autophagy , HSV
Ivermectin (MK-933) is a glutamate-gated chloride channel (GluCls) activator, with antiparasitic activity.
T37508 Meconin Endogenous Metabolite
Meconin, a noscapine metabolite, is a urinary detection marker for illicit opiate misuse. This product is intended for use as a forensic standard.
T0281 Meclocycline sulfosalicylate salt Meclutin,Mecloderm,Meclan Cream Antibacterial , Antibiotic
Meclocycline sulfosalicylate salt (Mecloderm), a tetracycline antibiotic, is used topically (i.e. for skin infections) as it is totally insoluble in water and may damage kidney and liver if given systemically.
T0956 Avermectin B1 Avermectin B1a-Avermectin B1b mixt.,Abamectin Antibiotic , Parasite , Autophagy
Avermectin B1 is served as anthelmintic and insecticide.
T0969 Doramectin Dectomax,Cyclohexylavermectin B1 Others , Antibiotic , Parasite
Doramectin (Dectomax) is an antiparasitic agent.
T11842 Levomecol Others
Levomecol, a broad-spectrum antibiotic derived from Streptomyces venezuelae, comprises Chloramphenicol and Methyluracil. It exerts its bacteriostatic effect by binding to the bacterial ribosome, inhibiting protein synthe...
T40929 Mechercharmycin A
Mechercharmycin A, a cytotoxic compound, was isolated from Thermoactinomyces sp. YM3-251, a marine source. It demonstrates potent antitumor activity.
T35743 Ivermectin B1a aglycone
Ivermectin B1a aglycone is an acid degradation product produced by hydrolysis of the disaccharide unit of ivermectin. It can inhibit nematode larval development, but does not cause paralytic activity.
T35752 Xanthoquinodin A1 Xanthoquinodin A1
Xanthoquinodin A1 is a fungal metabolite that has been found inHumicolaand has diverse biological activities.1,2It inhibitsE. tenellaschizont formation in BHK-21 cells with a minimum effective concentration (MEC) value o...

Natural Products

Pyromeconic acid
TL0015
Synonym: 3-hydroxy-4H-pyran-4-one
Target: Anti-infection
Demeclocycline hydrochloride
T1400
Synonym: Declomycin,Clortetrin,Detravis,Demeclocycline HCl
Target: ribosome, Antibacterial, Antibiotic
Ivermectin
T1131
Synonym: MK-933
Target: Mitophagy, GluCls, P2X Receptor, SARS-CoV, HIV Protease, Antibiotic, Parasite, Autophagy, HSV
Meconin
T37508
Synonym:
Target: Endogenous Metabolite
Meclocycline sulfosalicylate salt
T0281
Synonym: Meclutin,Mecloderm,Meclan Cream
Target: Antibacterial, Antibiotic
Avermectin B1
T0956
Synonym: Avermectin B1a-Avermectin B1b mixt.,Abamectin
Target: Antibiotic, Parasite, Autophagy
Doramectin
T0969
Synonym: Dectomax,Cyclohexylavermectin B1
Target: Others, Antibiotic, Parasite
Levomecol
T11842
Synonym:
Target: Others
Mechercharmycin A
T40929
Synonym:
Target:
Ivermectin B1a aglycone
T35743
Synonym:
Target:
Xanthoquinodin A1
T35752
Synonym: Xanthoquinodin A1
Target:

Recombinant Proteins

Species：
Human (5)
Myrmecia pilosula (1)
Staphylococcus aureus (1)
Expression System：
E. coli (4)
HEK293 Cells (2)
Baculovirus Insect Cells (1)
Tag：
C-6xHis (2)
N-10xHis, C-Myc (1)
N-6xHis-SUMO (1)
N-GST, C-6xHis (1)
N-His (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPY-03728 CCL28 Protein, Human, Recombinant (His) Human E. coli
CCL28 chemokine is expressed by epithelial cells of various mucosal tissues. This chemokine binds to CCR3 and CCR10 receptors and plays an essential role in the IgA antibody secreting cells (IgA-ASC) homing to mucosal su...
TMPJ-00019 CCL28 Protein, Human, Recombinant Human E. coli
Chemokine (C-C Motif) Ligand 28 (CCL28) is a novel chemokine that shares the most homology with CCL27/CTACK. CCL28 shows chemotactic activity for resting CD4, CD8 T-cells and eosinophils. It Binds to CCR3 and CCR10 and i...
TMPH-03035 M-myrmeciitoxin-Mp2b Protein, Myrmecia pilosula, Recombinant (GST & His) Myrmecia pilosula Baculovirus Insect Cells
Heterodimer protein that may serve both defensive (pain-inducing) and predatory (insecticidal) roles. Has membrane-disrupting activity and shows induction of non-specific calcium influx into cells,. Shows broad-spectrum ...
TMPJ-00460 MECR Protein, Human, Recombinant (His) Human HEK293 Cells
Trans-2-Enoyl-CoA Reductase Mitochondrial (MECR) belongs to the zinc-containing alcohol dehydrogenase family. MECR localizes to the mitochondrion. It is highly expressed in skeletal and heart muscle and expressed at lowe...
TMPJ-00998 MECP2 Protein, Human, Recombinant (His) Human HEK293 Cells
The MeCP2 helps regulate gene activity (expression) by modifying chromatin, the complex of DNA and protein that packages DNA into chromosomes. The MeCP2 protein is present in cells throughout the body, although it is par...
TMPH-03521 MecA Protein, S. aureus, Recombinant (His & SUMO) Staphylococcus aureus E. coli
Enables the recognition and targeting of unfolded and aggregated proteins to the ClpC protease or to other proteins involved in proteolysis. MecA Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expre...
TMPH-02254 Trypsin-1 Protein, Human, Recombinant (His & Myc) Human E. coli
Has activity against the synthetic substrates Boc-Phe-Ser-Arg-Mec, Boc-Leu-Thr-Arg-Mec, Boc-Gln-Ala-Arg-Mec and Boc-Val-Pro-Arg-Mec. The single-chain form is more active than the two-chain form against all of these subst...
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