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Cat No. | Product Name | Synonyms | Targets |
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T22269 | Benzyldodecyldimethylammonium Chloride Dihydrate | Antibacterial | |
Benzyldodecyldimethylammonium chloride dihydrate can be used as an insecticide reagent. It can target drug-resistant bacteria, such as methicillin-resistant Staphylococcus aureus, multidrug-resistant Pseudomonas aerugino... | |||
T36683 | Vedaprofen | Quadrisol,PM 150,CERM 10202 | COX , Antibacterial , Prostaglandin Receptor |
Vedaprofen (PM 150) inhibits COX-1 and reduces prostaglandin H2 synthesis with anti-inflammatory activities. Vedaprofen is an inhibitor of Escherichia coli sliding clamp with the IC50 of 222 μM and Ki of 131 μM. | |||
T82462 | Enterotoxin STp (E. coli) | ||
Enterotoxin STp (E. coli), a heat-stable enterotoxin, is applicable in vaccine research [1]. | |||
T9508 | MONOCAPRYLIN | Sefsol 318,Glyceryl monocaprylate | Antibacterial |
Monocaprylin (Sefsol 318) is a monoglyceride of caprylic acid with an excellent antibacterial activity. Monocaprylin inhibits a variety of foodborne pathogenic and spoilage microorganisms and has the potential for an alt... | |||
T19794 | Temafloxacin | Omniflox | Antibiotic |
Temafloxacin (Omniflox) is an antibiotic and antimycobacterial agent. It used to treat lower respiratory tract infections, genital and urinary infections like prostatitis, and skin infections. | |||
T1389 | Dyclonine hydrochloride | Dyclocaine hydrochloride,Dyclonine HCl | Sodium Channel , Antibacterial , Antifungal |
Dyclonine hydrochloride (Dyclonine HCl) , an over the counter throat lozenge, is found in Sucretswith local anesthetic effect . | |||
T1293 | Gatifloxacin | BMS 206584-01,PD 135432,CG5501,BMS-206584,AM-1155 | Topoisomerase , Antibacterial , Antibiotic |
Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. | |||
T39912 | 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine | 5'-O-DMT-dU | Others |
5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine (5'-O-DMT-dU) is a competitive dUTP nucleotidohydrolase (dUTPase) inhibitor(Ki > 1 mM) in E. coli. 5'-O-(4,4'-Dimethoxytrityl)-2'-deoxyuridine can be used in machine-assisted t... | |||
T13477 | β-Glucuronidase-IN-1 | Antibacterial | |
β-Glucuronidase-IN-1 is an E. coli β-glucuronidase (β-glucuronidase) inhibitor with a potent, selective, non-competitive, and orally active IC50 and Ki value of 283 nM and 164 nM, respectively, against E. coli β-glucuron... | |||
T12126 | MUT056399 | Fab-001 | Antibacterial |
MUT056399 (Fab-001) is a highly potent inhibitor of the FabI enzyme of both S. aureus and E. coli (IC50s of 12 nM and 58 nM, respectively). | |||
T10347L | Apidaecin IB acetate | Apidaecin IB acetate (123276-94-8 Free base) | Others |
Apidaecin IB acetate is an insect antibacterial peptide. The minimum concentration of apidaecin IB acetate against Escherichia coli (E. coli ML35, o18k1h7 and ATCC 25922) is 8 μM. | |||
T22387 | NSC 55655 | 5-[(2-nitrophenyl)methylidene]thiazolidine-2,4-dione | Others |
NSC 55655 (5-[(2-Nitrophenyl)methylene]-2,4-thiazolidinedione) possesses antimicrobial and antioxidant activities and inhibits the proliferation of B. subtilis, S. aureus, K. pneumonia, E. coli, S. typhi , A. niger and C... | |||
T11227L | Eravacycline dihydrochloride | TP-434-046,TP-434 dihydrochloride | Antibacterial |
Eravacycline dihydrochloride (TP-434-046) is a potent and broad-spectrum antibacterial agent against six E. coli (MICs: 0.125-0.25 mg/L). | |||
TP1663L | CysHHC10 acetate | CysHHC10 acetate(1408311-03-4 free base) | Antibacterial |
CysHHC10 acetate shows antibacterial activities against both Gram-positive and Gram-negative bacteria with MIC of 10.1, 20.2, 2.5, and 1.3 mM for E. coli, P. aeruginosa, S. aureus, and S. epidermidis, respectively. | |||
T10337 | Antimicrobial Compound 1 | Antibacterial | |
Antimicrobial Compound 1 is an alkyl pyridinium compound with Tail 12C, Head 4-carboxyl. Antimicrobial Compound 1 exhibits antimicrobial activities against B. subtilis and E. coli. | |||
TP1496L | P5 Ligand for Dnak and DnaJ acetate | p5 Ligand for Dnak and DnaJ acetate(209518-24-1 free base) | HSP |
p5 Ligand for Dnak and DnaJ acetate is a nonapeptide. It is a high-affinity ligand for DnaK (E. coli Hsp70) and DnaJ (E. coli Hsp40). | |||
T77615 | ND-011992 | ND011992 | Mitochondrial Metabolism , Antibacterial |
ND-011992 is a reversible and selective quinazoline inhibitor targeting quinone reductases and quinol oxidases.ND-011992 inhibits E. coli BL21*Δcyo respiratory complex I. ND-011992 inhibits bo3 oxidase, bd-I oxidases and... | |||
TQ0018 | 6-Amino-5-azacytidine | Antibacterial | |
6-Amino-5-azacytidine has an inhibitory of the growth of E. coli. | |||
T33828 | O-Succinylhomoserine | O-Succinyl-L-homoserine | Others |
O-Succinylhomoserine (O-Succinyl-L-homoserine) is an intermediate in the synthesis of cystathionine by E coli.. | |||
T11876 | LpxH-IN-AZ1 | Antibacterial | |
LpxH-IN-AZ1 is a potent inhibitor of the UDP-2,3-diacylglucosamine pyrophosphate hydrolase, LpxH, and sulfonylpiperazine compounds.LpxH-IN-AZ1 exhibits antimicrobial activity and inhibits Klebsiella pneumoniae with an IC... | |||
T20936 | Lauramine oxide | LDAO,Dimethylaurylamine oxide,Refan,Lauryldimethylamine oxide | Antibacterial |
Lauramine oxide (Refan) is effective against common bacteria such as E. coli and S. aureus, however it is non-denaturing and may be used to solubilize proteins. | |||
T32490 | L-161240 | L-161,240 | Antibacterial |
L-161240 is an antimicrobial agent associated with lipid A biosynthesis with an IC50 value of 30 nM as determined by DEACET and a MIC value of 1-3 μg/ mL against wild-type E. coli. | |||
T60247 | Diethylamine NONOate diethylammonium salt | NOC-18 Diethylamine,DEA NONOate diethylamine | Antibiotic |
Diethylamine NONOate diethylammonium salt (DEA NONOate diethylamine) is a nitric oxide donor with antibacterial activity, a dispersant for preformed biofilms of Pseudomonas aeruginosa and inhibits the growth of E. coli. ... | |||
T6638 | Retapamulin | SB-275833 | ribosome , Antibacterial , Antibiotic |
Retapamulin (SB-275833), a Pleuromutilin Antibacterial, binds to both E. coli and S. aureus ribosomes with similar potencies (Kd: 3 nM). | |||
TP1773L | PGLa acetate | Antibacterial , Antibiotic | |
PGLa acetate is a 21-residue member of the magainin family of antibiotic peptides. | |||
T1569 | Tigecycline | GAR-936 | ribosome , Antibacterial , Antibiotic , Autophagy |
Tigecycline (GAR-936) is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome co... | |||
T5413 | ML216 | CID-49852229 | DNA/RNA Synthesis |
ML216 (CID-49852229) is a small molecule inhibitor of BLM helicase (IC50: 1.8 μM). It showed 28-fold selective against the related helicases RECQ1, RECQ5, and E. coli UvrD (IC50s > 50 μM). | |||
T11348 | G907 | Antibiotic | |
G907 is a selective and potent antagonist of the small molecule ATP-binding cassette (ABC) transporter protein MsbA, with bactericidal activity, which traps MsbA in the inner lipopolysaccharide. G907 inhibits E. coli Msb... | |||
T9727 | 2'-Fluoro-2'-Deoxyadenosine | Nucleoside Antimetabolite/Analog | |
2'-Fluoro-2'-Deoxyadenosine is efficiently cleaved to the toxic 2-fluoroadenine (FAde) by Escherichia coli purine nucleoside phosphorylase (PNP). 2'-Fluoro-2'-Deoxyadenosine showed good in vivo activity against tumors ex... | |||
T21831 | UCM05 | G28UCM | Fatty Acid Synthase |
UCM05 (G28UCM) is a potent inhibitor of fatty acid synthase (FASN) with efficacy against HER2+ breast cancer xenografts, including in cell lines resistant to anti-HER2 drugs [1]. Additionally, it functions as an inhibito... | |||
T38164 | MnTBAP chloride | Mn(III)TBAP | |
MnTBAP chloride (Mn(III)TBAP) is a cell-permeable superoxide dismutase (SOD) mimetic and peroxynitrite scavenger that reduces the doubling time of SOD-E. coli by a factor of 2. MnTBAP chloride exhibits anti-inflammatory ... | |||
T36352 | Suc-Leu-Tyr-AMC | ||
Suc-Leu-Tyr-AMC is a fluorescent substrate for calpain I and II and papain (another cysteine protease) that is used for measuring the chymotrypsin-like peptidase activity of the 20S proteasome (excitation max: 360 nm; em... | |||
T41275 | PF-04753299 | Others | |
PF-04753299 is a potent and selective inhibitor of UDP-3-O-(R-3-hydroxymyristol)-N-acetylglucosamine deacetylase (LpxC), demonstrating bactericidal effects against gonococcal isolates. It exhibits inhibitory activity aga... | |||
T77675 | TNKS-2-IN-1 | PARP , Wnt/beta-catenin , Antibiotic | |
TNKS-2-IN-1 is a TNKS-2 inhibitor.TNKS-2-IN-1 inhibits TNKS-1 and TNKS-2 with IC50s of 259 nM and 1100 nM, respectively.TNKS-2-IN-1 has antimicrobial activity against E. coli and S. aureus.TNKS-2-IN-1 inhibits the releas... | |||
T35449 | α-(difluoromethyl)-DL-Arginine | DFMA,RMI 71897,α-(difluoromethyl)-DL-Arginine | Others |
α-(difluoromethyl)-DL-Arginine (RMI 71897) is an enzyma-activated, irreversible inhibitor of arginine decarboxylase for E. coli (Ki = 800 μM), Pseudomonas aeruginosa, and Klebsiella pneumoniae. At 0.01 mM, it has been sh... | |||
T3097 | Mycophenolic Acid Impurity | 5,7-dihydroxy-4-methylphthalide | Others |
Mycophenolic Acid Impurity (5,7-dihydroxy-4-methylphthalide) is an an immunosuppresant drug and potent anti-proliferative, and can be used in place of the older anti-proliferative azathioprine. It is usually used as part... | |||
T31854 | Formylmethionyl-alanyl-leucine | Fmet-ala-leu | |
Formylmethionyl-alanyl-leucine is formed by E coli ribosomal protein L10 gene. | |||
T24527 | Netzahualcoyone | ||
Netzahualcoyone inhibited the respiration of intact cells of B. subtilis but had no effect on the respiration of E. coli. | |||
TP2336 | Tripalmitoyl pentapeptide | P3C-Ssna,Bpppcssaa,Bppp cssaa,Bppp-cssaa,P3C Ssna P3CSsna | |
Tripalmitoyl pentapeptide is a Mitogen from E Coli lipoprotein. It also is a potent macrophage B lymphocyte activator. | |||
T37873 | CAP 3 | ||
CAP 3 is a cholic acid-peptide conjugate (CAP) with antibacterial activity. It is active against the Gram-negative bacteria E. coli, K. pneumoniae, and A. baumanii (MIC99s = 8, 16, and 16 μM, respectively). CAP 3 increas... | |||
T14043 | 4-(tert-Butyl)-benzhydroxamic Acid | Others | |
4-(tert-Butyl)-benzhydroxamic Acid is a PqsR antagonist with IC50s of 12.5 μM and 23.6 μM for E. coli and P. aeruginosa, respectively, and it reduces the production of the virulence factor pyocyanin in P. aeruginosa with... | |||
T81157 | SIGSLAK | ||
SIGSLAK comprises the active site analogous to that of Escherichia coli (E. coli) penicillin-binding protein 1b (PBP 1b) [1]. | |||
T80371 | Distinctin | ||
Distinctin, an antimicrobial peptide derived from frog skin, exhibits antibacterial activity against a range of pathogens including E. faecalis, P. aeruginosa, S. aureus, and E. coli, with minimum inhibitory concentratio... | |||
T63512 | LpxC-IN-10 | ||
LpxC-IN-10 is a selective LpxC inhibitor with an MIC of 0.5 μg/mL against E. coli and K. pneumoniae and is capable of being used to study bacterial infections. | |||
T80199 | LfcinB 17–28 TFA | ||
LfcinB 17–28 TFA, a fragment of Bovine Lactoferricin (LfcinB), exhibits weak antimicrobial activity, with a minimum inhibitory concentration (MIC) of 200 μM against E. coli [1]. | |||
T10347 | Apidaecin IB | Antibacterial | |
Apidaecin IB is an insect antimicrobial peptide, with MIC values of 8 μM for E. coli (O18K1H7, ML35 and ATCC 25922). | |||
T83748 | RW4 TFA | (RW)4-NH2,Arg-Trp-Arg-Trp-Arg-Trp-Arg-Trp-NH2 | |
RW4, an antimicrobial peptide, exhibits activity against E. coli and S. aureus, with IC50 values of 9.6 and 5.1 µM, respectively. Additionally, it induces hemolysis of isolated ovine erythrocytes. | |||
T80294 | GLK-19 | ||
GLK-19, an antimicrobial peptide, exhibits activity against E. coli with a minimum inhibitory concentration (MIC) of 10 μM [1]. | |||
T83830 | 2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate sodium | 2′-fluoro-2′-deoxy ATP,AfTP,2'-fluoro dATP | |
2'-Deoxy-2'-fluoroadenosine-5'-O-triphosphate is a fluorinated analog of ATP, the pivotal energy substrate for cellular metabolism, and acts as an inhibitor of E. coli RNA polymerase (Ki = 200 µM). | |||
T80284 | LMW peptide | ||
LMW peptide, an antimicrobial peptide, exhibits activity against both Gram-positive and Gram-negative bacteria, including B. subtilis, L. monocytogenes, E. coli, P. aeruginosa, and V. cholera [1]. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T41078 | Lipopolysaccharides, Escherichiacoli | Lipopolysaccharide, E. coli O111:B4 | Others |
Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) is a unique component of the cell wall of Gram-negative bacteria, consisting of three regions: lipid A, oligosaccharide core and O-specific polysaccharide (O-antigen... | |||
T1313 | Nitrofurantoin | Furadantine,Macrodantin,Furadonine | Antibacterial , Antibiotic |
Nitrofurantoin (Furadantine), an antibiotic, inhibits bacterial DNA, RNA, and cell wall protein synthesis. Activated by bacterial flavoproteins to intermediates that inactivate bacterial ribosomal proteins, Nitrofurantoi... | |||
T8384 | Gatifloxacin hydrochloride | AM-1155 (hydrochloride),BMS-206584 (hydrochloride),PD135432 (hydrochloride) | Topoisomerase , Antibacterial , Antibiotic |
Gatifloxacin hydrochloride (AM-1155 hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, which can inhibit the bacterial enzyme DNA rotase and topoisomerase IV. | |||
T1100 | Polymyxin B Sulfate | Aerosporin,PMB,Polymyxin B sulphate,Polymyxin B sulfate (1404-26-8 free base),Poly-RX | Antibacterial , Antibiotic |
Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Po... | |||
T4913 | Maleic acid | Endogenous Metabolite , Antibacterial | |
Maleic Acid is a Glutamate Decarboxylase (GAD) inhibitor of L. monocytogenes and E. coli. | |||
T19146 | 5,6-Dihydrouridine | Endogenous Metabolite | |
5,6-Dihydrouridine is a modified base found in conserved positions in the D-loop of tRNA in Eukaryota, Bacteria, and some Archaea. | |||
T13708 | Glycol chitosan | Antibacterial | |
Glycol chitosan is a chitosan derivative with hydrophilic ethylene glycol branches. Glycol chitosan inhibits E. coli, S. aureus, and S. enteritidis growths (MICs: 4 μg/mL, 32 μg/mL, and <0.5 μg/mL). It enhances membrane ... | |||
TN2898 | Kaempferol-7,4'-dimethyl ether | 3,5-Dihydroxy-4',7-dimethoxyflavone | Antioxidant , Antifection |
Kaempferol-7,4'-dimethyl ether is isolated from the rhizomes of Zingiber phillipseae and exhibits antioxidant activity against S. aureus and E. coli with MICs at 200 and 225 μg/ml, respectively. | |||
TN2281 | Sinapaldehyde | trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde | Antibacterial |
Sinapaldehyde (trans-3,5-Dimethoxy-4-hydroxy cinnamaldehyde) is a natural product. Sinapaldehyde exhibits moderate antibacterial against Methicillin resistant S. aureus (MRSA) and E. coli with MIC values of 128 and 128 μ... | |||
T37267 | Pachybasin | Antibacterial | |
Pachybasin is an anthraquinone fungal metabolite. Pachybasin shows antimicrobial activities against E. coli, B. subtilis, M. luteus, S. cerevisiae, C. albicans, A. niger, and A. flavus, with MIC values of 64.0 μg/mL, and... | |||
T0710 | L-Cycloserine | Levcycloserine,Levcicloserina,(-)-Cycloserine,(S)-Cycloserine,Levcycloserinum,(S)-4-Amino-3-isoxazolidone | HIV Protease , GABA Receptor |
L-Cycloserine ((-)-Cycloserine) irreversibly inhibits GABA pyridoxal 5′-phosphate-dependent aminotransferase in E. coli, as well in the brains of various animals, results in increased levels of gamma-aminobutyric acid (G... | |||
T4010 | Juglone | 5-Hydroxy-1,4-naphthoquinone,Regianin | DNA/RNA Synthesis , Antibacterial |
Juglone (Regianin) is a natural naphthoquinone found in the black walnut (J. nigra) and other plants in the Juglandaceae family. Juglone also irreversibly inhibits peptidyl-prolyl cis/trans isomerases of the parvulin fam... | |||
T4788 | L-Norvaline | Others , Endogenous Metabolite | |
L-Norvaline is an arginase inhibitor and a non-proteinogenic branched-chain amino acid. L-Norvaline has previously been reported to be a natural component of an antifungal peptide of Bacillus subtilis. L-Norvaline and ot... | |||
T10933 | D-Cysteine | Endogenous Metabolite , Antibacterial | |
D-Cysteine is the D-isomer of cysteine and a powerful inhibitor of the growth of E. coli. D-cysteine is mediated by D-amino acid oxidase to produce H2S, and is a neuroprotective agent against cerebellar ataxia. D-cystein... | |||
T72250 | 4aα,7α,7aα-Nepetalactone | ||
4aα,7α,7aα-Nepetalactone exhibits antibacterial properties, effectively inhibiting the growth of Escherichia coli (E. coli), Pseudomonas aeruginosa, Staphylococcus aureus, Salmonella typhi, and Enterococcus faecalis. | |||
TN3650 | Chrysothol | Antifection | |
Chrysothol shows strong antimicrobial activities (MICs=50-100 ug/ml) against enterobacteria E. coli and S. enteritidis. It also shows anti-cancer activity against human breast cancer cells. | |||
T36815 | Chevalone C | ||
Chevalone C is a meroterpenoid fungal metabolite originally isolated from E. chevalieri. It is active against M. tuberculosis H37Ra (MIC = 6.3 μg/ml) and is cytotoxic to BC1 human breast cancer cells (IC50 = 8.7 μg/ml). ... | |||
TN4927 | Rupesin E | Antifection | |
Rupesin E shows significant antibacterial activities against Escherichia coli. | |||
T80330 | XT-1 | ||
XT-1, an antimicrobial peptide sourced from Xenopus tropicalis skin secretions, exhibits potent activity against S. aureus, E. coli, and C. albicans, with minimum inhibitory concentration (MIC) values of 5, 6, and 50 μM,... | |||
T10455 | Bafilomycin B1 | Others | |
Bafilomycin B1, a macrolide antibiotic isolated from Streptomyces sp, acts as an inhibitor of K+-dependent ATPase of E. coli. It also inhibits Gram-positive bacteria and fungi. | |||
T80020 | UDP-3-O-acyl-GlcNAc diammonium | UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine diammonium | Endogenous Metabolite |
UDP-3-O-acyl-GlcNAc diammonium serves as a metabolite in E. coli, playing a critical role in the biosynthesis pathway of 3-deoxy-D-manno-octulosonate (KDO) [1]. | |||
TN2809 | 22-Dehydroclerosterol | Antifection | |
22-Dehydroclerosterol has antibacterial activity against against E. coli, S. aureus, and H. pylori. | |||
TN1991 | Norchelerythrine | Antifection | |
Norchelerythrine shows significant inhibitory activity against Staphylococcus aureus ATCC 6538 with MIC values ranging from 12.5 to 50 ug/mL. It exhibits strong antifeeding activity in a concentration-dependant manner wi... | |||
TN1538 | Curzerenone | Caspase , Antifection | |
Curzerenone holds great promise for use in chemopreventive and chemotherapeutic strategies, it has slightly effective against E. coli (IZ = 10.8 ± 0.52). | |||
T75685 | UDP-3-O-acyl-GlcNAc | ||
UDP-3-O-acyl-GlcNAc (UDP-3-O-(3-hydroxytetradecanoyl)-N-acetylglucosamine), an E. coli metabolite, plays a role in the 3-deoxy-D-manno-octulosonate (KDO) biosynthesis pathway [1]. | |||
T40436 | N,N'-Diacetylchitobiose | ||
N,N'-Diacetylchitobiose, a dimer of β(1,4) linked N-acetyl-D glucosamine, is derived from the hydrolysis of chitin. This compound serves as an alternative carbon source for E. coli. | |||
T80001 | Majoranaquinone | Antibiotic | |
Majoranaquinone demonstrates potent antibacterial activity against four Staphylococcus strains, one Moraxella strain, and one Enterococcus strain. It also acts as an effective efflux pump inhibitor in Escherichia coli AT... | |||
T38275 | Kirromycin | ||
Kirromycin is an antibiotic originally isolated from Streptomyces and an inhibitor of protein biosynthesis. It inhibits isoleucine incorporation, polyphenylalanine synthesis, and growth of B. brevis. Kirromycin inhibits ... | |||
TN5229 | Vibralactone B | Antifection | |
Vibralactone B shows antibacterial activity, it can inhibit significantly the growth of E. coli and Pseudomonas aeruginosa, with MBC values of 50 and 100 ug/mL, respectively. | |||
TN3978 | Epitaraxerol | Antifection | |
Epitaraxerol shows moderate antifungal activity against C. albicans and low antimicrobial activity against T. mentagrophytes, A. niger, S. aureus, E. coli, P. aeruginosa, and B. subtilis. | |||
T83920 | 4-Trehalosamine | ||
4-Trehalosamine, a microbial metabolite identified in Streptomyces, exhibits antibiotic properties. Demonstrating efficacy in cup assays, it is active against E. coli, K. pneumoniae, and B. subtilis at concentrations of ... | |||
T39626 | Orotidine 5′-monophosphate | Orotidine monophosphate,Orotidylicacid,Orotidine 5′-monophosphate | |
Orotidine 5′-monophosphate, a pyrimidine ribonucleoside, functions as an endogenous metabolite in human, E. coli, and mouse processes. It serves as an intermediate in uridine monophosphate (UMP) biosynthesis and is utili... | |||
T83902 | Polymyxin E1 sulfate | Colistin A sulfate | |
Polymyxin E1, a peptide antibiotic and key component of the cationic lipopeptide antibiotic colistin, was initially extracted from B. polymyxa. It demonstrates effectiveness against P. aeruginosa and E. coli, with minimu... | |||
T83918 | Clazamycin A hydrochloride | NSC 332188 | |
Clazamycin A, a microbial metabolite and antibiotic derived from Streptomyces, exhibits efficacy against several bacteria, namely S. aureus, B. anthracis, B. subtilis, E. coli, and P. aeruginosa, with minimum inhibitory ... | |||
T80331 | XT-2 peptide | ||
XT-2 peptide, an antimicrobial agent sourced from the skin secretions of Xenopus tropicalis, exhibits potent activity against E. coli, with a minimum inhibitory concentration (MIC) of 8 μM [1]. | |||
T80342 | XT-4 | ||
XT-4, an antimicrobial peptide originating from the skin secretions of Xenopus tropicalis, exhibits potent activity against E. coli, with a minimum inhibitory concentration (MIC) valued at 18 μM [1]. | |||
T38258 | Phanerosporic Acid | ||
Phanerosporic acid is a fungal secondary metabolite originally isolated from P. chrysosporum that has antibacterial activity against B. cereus, B. subtilis, and E. coli and antifungal activity against S. cerevisiae, A. n... | |||
TN5014 | Shoreic acid | Antifection , HSV | |
Shoreic acid exhibits antibacterial activity against E. coli, P. aeruginosa, S. aureus, and B. subtilis with activity indices (AI) of 0.2, 0.3, 0.5 and 0.4, respectively, it also shows antifungal activity against C. albi... | |||
T75439 | Angustifoline hydrochloride | ||
Angustifoline hydrochloride, an alkaloid derived from Lupinus angustifolius L. extract, demonstrates antimicrobial efficacy, potentially exhibiting bacteriostatic effects against S. aureus, B. subtilis, E. coli, P. aerug... | |||
T37442 | Aspergillin PZ | ||
Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis ... | |||
T83862 | Bactobolin A hydrochloride | BN-183B | |
Bactobolin A, a microbial metabolite initially derived from Pseudomonas, exhibits both antibiotic and anticancer properties. It demonstrates activity against various bacteria including S. aureus, S. epidermidis, S. faeca... | |||
T38086 | Neohydroxyaspergillic Acid | ||
Neohydroxyaspergillic acid is a fungal metabolite produced by A. sclerotiorum that has antibiotic and antifungal activities. It inhibits the growth of P. aeruginosa, M. smegmatis, S. aureus, E. coli, K. pneumoniae, B. my... | |||
T80343 | MCF | ||
MCF, an antimicrobial peptide originating from bee venom, exhibits activity against E. coli W 160-37, S. aureus 8530, and B. subtilis, with minimum inhibitory concentration (MIC) values of 35-45 μg/ml, 25-35 μg/ml, and 1... | |||
TN4264 | Isoapetalic acid | HIV Protease , Antifection | |
Isoapetalic acid and apetalic acid exhibit cytotoxic activities towards both cancer cell lines(human breast cancer (MCF-7) and human lung carcinoma (A-549) cell lines) and both Gram-positive bacteria(two Gram-positive ba... | |||
TN4402 | Labd-13-ene-8,15-diol | Antifection | |
13(E)-Labd-13-ene-8alpha,15-diol shows antiviral and anticancer activity, it shows strong anti-HRV2 and HRV3 activity with a 50% inhibitory concentration (IC50) of 2.68 and 0.87 microg/mL,respectively; it also exhibits a... | |||
T36417 | Nargenicin | Antibiotic 47444 | |
Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive... | |||
T83693 | Magainin 2 TFA | MG2 | |
Magainin 2, a cationic peptide derived from the African clawed frog (X. laevis) skin, exhibits host defense and antimicrobial properties. This compound effectively inhibits a range of pathogens, including E. coli, K. pne... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00699 | BamA Protein, E. coli, Recombinant (His) | E. coli | P. pastoris (Yeast) |
BamA Protein, E. coli, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 30 kDa and the accession number is P0A940. | |||
TMPJ-01463 | IL-2 Protein, Human, Recombinant (E. coli) | Human | E. coli |
IL-2 Protein, Human, Recombinant (E. coli) is expressed in E. coli expression system. The accession number is P60568. | |||
TMPY-00541 | LON PROTEASE Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Lon protease, an ATP-dependent mitochondrial protease, is important in mitochondrial protein maintenance. Lon protease is a multifunctional enzyme, and its functions include the degradation of damaged proteins and natura... | |||
TMPY-03650 | BirA Protein, E. coli, Recombinant (His & MBP) | E. coli | E. coli |
The enzyme BirA is a key reagent because of its ability to biotinylate proteins at a specific residue in a recognition sequence. This enzyme is used to biotinylate the C termini of membrane proteins, allowing these prote... | |||
TMPY-06983 | IFN gamma Protein, Human, Recombinant (E. coli) | Human | E. coli |
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, ... | |||
TMPJ-00662 | RANKL/TNFSF11/CD254 Protein, Human, Recombinant (E. coli) | Human | E. coli |
CD254, also known as RANKL, TNFSF11, TRANCE, OPGL and ODF, is a type II membrane protein of the tumor necrosis factor (TNF) superfamily, and affects the immune system and control bone regeneration and remodeling. RANKL i... | |||
TMPJ-01465 | GM-CSF/CSF2 Protein, Human, Recombinant (E. coli) | Human | E. coli |
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF) was initially characterized as a growth factor that can support the in vitro colony formation of granulocyte-macrophage progenitors. It is produced by a number of... | |||
TMPJ-01467 | Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) | Human | E. coli |
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ... | |||
TMPY-06981 | IL-1 alpha/IL-1A Protein, Human, Recombinant (E. coli) | Human | E. coli |
IL-1 alpha is a member of the interleukin 1 cytokine family. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proli... | |||
TMPH-00731 | RpoS Protein, E. coli, Recombinant | E. coli | E. coli |
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the master transcriptional regulator of the stationary phase and... | |||
TMPH-00636 | Hemolysin E, chromosomal Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Toxin, which has some hemolytic activity towards mammalian cells. Acts by forming a pore-like structure upon contact with mammalian cells. | |||
TMPH-00728 | FliA Protein, E. coli, Recombinant | E. coli | E. coli |
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. FliA Protein, E.... | |||
TMPH-00745 | TsaE Protein, E. coli, Recombinant | E. coli | E. coli |
Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of thre... | |||
TMPH-00595 | HtpG Protein, E. coli, Recombinant | E. coli | E. coli |
Molecular chaperone. Has ATPase activity. | |||
TMPH-00624 | Flagellin Protein, E. coli, Recombinant | E. coli | E. coli |
Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella. Flagellin Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 51.2 kD... | |||
TMPH-00744 | CsrA Protein, E. coli, Recombinant | E. coli | E. coli |
A key translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Mediates global changes in gene expression, shifting from rapid growth to stress survival by linking envelope stress... | |||
TMPY-02375 | AcnB Protein, E. coli, Recombinant | E. coli | E. coli |
Escherichia coli contains two major aconitases (Acns), AcnA and AcnB. They are distantly related monomeric Fe-S proteins that contain different arrangements of four structural domains. acnA is specifically subject to Sox... | |||
TMPH-00696 | OmpC Protein, E. coli, Recombinant | E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ... | |||
TMPY-02798 | NEIL1 Protein, Human, Recombinant (His) | Human | E. coli |
NEIL1 is a member of DNA glycosylases. DNA glycosylases are a family homologous to the bacterial Fpg/Nei family. They play a role in base excision repair which is the mechanism by which damaged bases in DNA are removed a... | |||
TMPH-00752 | YncE Protein, E. coli, Recombinant (His) | E. coli | E. coli |
YncE Protein, E. coli, Recombinant (His) is expressed in E. coli with C-terminal 6xHis tag. The predicted molecular weight is 36.3 kDa. Accession number: P76116 | |||
TMPH-00626 | GPR Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. GPR Protein, E. coli, R... | |||
TMPH-00738 | TetR5 Protein, E. coli, Recombinant (His) | E. coli | E. coli |
TetR is the repressor of the tetracycline resistance element; its N-terminal region forms a helix-turn-helix structure and binds DNA. Binding of tetracycline to TetR reduces the repressor affinity for the tetracycline re... | |||
TMPH-00612 | MutL Protein, E. coli, Recombinant (His) | E. coli | E. coli |
This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable co... | |||
TMPH-00727 | FliA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor controls the expression of flagella-related genes. | |||
TMPH-00594 | HtpG Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Molecular chaperone. Has ATPase activity. | |||
TMPH-00599 | LDCC Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Plays a role in lysine utilization by acting as a lysine decarboxylase. | |||
TMPH-00732 | RtcB Protein, E. coli, Recombinant (His) | E. coli | P. pastoris (Yeast) |
GTP-dependent RNA ligase that is involved in tRNA splicing and RNA repair. Joins RNA with 2',3'-cyclic-phosphate or 3'-phosphate ends to RNA with 5'-hydroxy ends. Also acts as a DNA ligase in case of DNA damage by splici... | |||
TMPH-00617 | MazF Protein, E. coli, Recombinant (His) | E. coli | P. pastoris (Yeast) |
MazF Protein, E. coli, Recombinant (His) is expressed in yeast with C-6xHis tag. The predicted molecular weight is 13.6 kDa and the accession number is P0AE70. | |||
TMPH-00621 | NfuA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged ... | |||
TMPH-00570 | MsyB Protein, E. coli, Recombinant (His) | E. coli | Baculovirus Insect Cells |
Could participate in the normal pathway of protein export. MsyB Protein, E. coli, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 16.3 kDa and the accession ... | |||
TMPY-02390 | SSPA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Stringent starvation protein A (ssPA), a member of the GST superfamily, is an RNA polymerase-associated transcriptional activator for the lytic development of phage P1 and is essential for stationary phase-induced acid t... | |||
TMPJ-00787 | GUSB Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Beta-D-glucuronidase from E.coli is a highly specific enzyme in hydrolyzing glucuronides. Beta-D-glucuronidase (GLUase) activity can be measured as the rate of production of fluorescent methylumbelliferone (MU), resulti... | |||
TMPH-00708 | DegP Protein, E. coli, Recombinant (His) | E. coli | P. pastoris (Yeast) |
DegP acts as a chaperone at low temperatures but switches to a peptidase (heat shock protein) at higher temperatures. Degrades transiently denatured and unfolded or misfolded proteins which accumulate in the periplasm fo... | |||
TMPH-00695 | OmpC Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Forms pores that allow passive diffusion of small molecules across the outer membrane.; (Microbial infection) Supports colicin E5 entry in the absence of its major receptor OmpF.; (Microbial infection) A mixed OmpC-OmpF ... | |||
TMPH-00610 | GyrA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to maintain chromosomes in an underwound state. This makes better substrates for topoisomerase IV (Pa... | |||
TMPH-00591 | SpeA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the biosynthesis of agmatine from arginine. | |||
TMPH-00753 | UspD Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Required for resistance to DNA-damaging agents. | |||
TMPH-00746 | FimH Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals ... | |||
TMPH-00722 | PykF Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the formation of pyruvate in the last step of glycolysis, it is irreversible under physiological conditions. The reaction is critical for the control of metabolic flux in the second part of glycolysis. | |||
TMPH-00653 | LoiP Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Metalloprotease that cleaves substrates preferentially between Phe-Phe residues. Plays a role in response to some stress conditions. Seems to regulate the expression of speB. | |||
TMPH-00592 | DnaK Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Acts as a chaperone. | |||
TMPH-00726 | Ribokinase Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a compone... | |||
TMPH-00604 | CDTA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
CDTs are cytotoxins which induce host cell distension, growth arrest in G2/M phase, nucleus swelling, and chromatin fragmentation in HeLa cells. CdtA, along with CdtC, probably forms a heterodimeric subunit required for ... | |||
TMPH-00750 | YcbX Protein, E. coli, Recombinant (GST) | E. coli | E. coli |
YcbX Protein, E. coli, Recombinant (GST) is expressed in E. coli. | |||
TMPJ-00819 | Trp A Protein, E. coli, Recombinant | E. coli | E. coli |
Trp A Protein, E. coli, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 27 KDa and the accession number is P0A877. | |||
TMPH-00698 | OmpA Protein, E. coli, Recombinant (His) | E. coli | E. coli |
OmpA Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 38.0 kDa and the accession number is P0A910. | |||
TMPH-00578 | NrdD Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Catalyzes the conversion of ribonucleotides into deoxyribonucleotides, which are required for DNA synthesis and repair. NrdD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag.... | |||
TMPH-00575 | GlpD Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Conversion of glycerol 3-phosphate to dihydroxyacetone. Uses molecular oxygen or nitrate as electron acceptor. GlpD Protein, E. coli, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The pred... | |||
TMPH-00641 | YTFE Protein, E. coli, Recombinant (GST) | E. coli | E. coli |
Di-iron-containing protein involved in the repair of iron-sulfur clusters damaged by oxidative and nitrosative stress conditions. YTFE Protein, E. coli, Recombinant (GST) is expressed in E. coli expression system with N-... | |||
TMPH-00741 | Rho Protein, E. coli, Recombinant (His) | E. coli | E. coli |
Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template. RNA-dependent NTPase wh... | |||
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