Powder: -20°C for 3 years | In solvent: -80°C for 1 year
LpxH-IN-AZ1 is a potent inhibitor of the UDP-2,3-diacylglucosamine pyrophosphate hydrolase, LpxH, and sulfonylpiperazine compounds.LpxH-IN-AZ1 exhibits antimicrobial activity and inhibits Klebsiella pneumoniae with an IC50 of 0.36 μM.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 50.00 | |
5 mg | In stock | $ 122.00 | |
10 mg | In stock | $ 193.00 | |
25 mg | In stock | $ 455.00 | |
50 mg | In stock | $ 669.00 | |
100 mg | In stock | $ 953.00 | |
500 mg | In stock | $ 1,920.00 |
Description | LpxH-IN-AZ1 is a potent inhibitor of the UDP-2,3-diacylglucosamine pyrophosphate hydrolase, LpxH, and sulfonylpiperazine compounds.LpxH-IN-AZ1 exhibits antimicrobial activity and inhibits Klebsiella pneumoniae with an IC50 of 0.36 μM. |
Targets&IC50 | LpxH (Klebsiella pneumoniae):0.36 μM, LpxH (E. coli):0.14 μM |
In vitro | LpxH-IN-AZ1 (1 μM) inhibits K. pneumoniae LpxH activity by 75% and E. coli LpxH activity by 83% when 100 μM UDPDAGn is present[1]. Additionally, it exhibits IC50 values of 0.36 μM for K. pneumoniae LpxH and 0.14 μM for E. coli LpxH[1]. |
Molecular Weight | 453.48 |
Formula | C21H22F3N3O3S |
CAS No. | 901260-40-0 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 22.67 mg/mL (50 mM), Sonification and heating are recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
LpxH-IN-AZ1 901260-40-0 Microbiology/Virology Antibacterial LpxHINAZ1 LpxH-IN-AZ-1 LpxH IN AZ1 inhibitor inhibit