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Tigecycline

Catalog No. T1569 CAS 220620-09-7

Synonyms: GAR-936

Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Tigecycline, CAS 220620-09-7

Pack Size	Availability	Price/USD
5 mg	In stock	$ 32.00
10 mg	In stock	$ 52.00
25 mg	In stock	$ 72.00
50 mg	In stock	$ 107.00
100 mg	In stock	$ 171.00
200 mg	In stock	$ 261.00
500 mg	In stock	$ 439.00
1 mL * 10 mM (in DMSO)	In stock	$ 54.00

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Purity: 100%

Purity: 99.94%

Biological Description

Chemical Properties

Storage & Solubility Information

Description	Tigecycline is a broad-spectrum glycylcycline antibiotic derived from tetracycline. Tigecycline binds to the 30S ribosomal subunit, thereby interfering with the binding of aminoacyl-tRNA to the mRNA-ribosome complex.
Targets&IC50	A. baumannii:1 mg/mL (MIC50), A. baumannii:2 mg/mL (MIC90), E. coli:125 ng/mL (Mean MIC)

Synonyms	GAR-936
Molecular Weight	585.65
Formula	C29H39N5O8
CAS No.	220620-09-7

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 2 years

Solubility Information

Ethanol: <1 mg/mL

DMSO: 93 mg/mL (158.8 mM)

H2O: 92 mg/mL (157.1 mM)

( < 1 mg/ml refers to the product slightly soluble or insoluble )

References and Literature

1. Livermore DM, et al. J Antimicrob Chemother, 2005, 56(4), 611-614. 2. Stein GE, et al. Clin Infect Dis, 2006, 43(4), 518-524. 3. Petersen PJ, et al. Antimicrob Agents Chemother, 2002, 46(8), 2595-2601.

Related compound libraries

This product is contained In the following compound libraries：

Anti-COVID-19 Compound Library Bioactive Compounds Library Max Human Metabolite Library FDA-Approved & Pharmacopeia Drug Library Approved Drug Library Drug Repurposing Compound Library Anti-Aging Compound Library Anti-Cancer Approved Drug Library Antibiotics Library Immunology/Inflammation Compound Library

Related Products

Related compounds with same targets

6-Diazo-5-oxo-L-nor-Leucine Trovafloxacin Nanchangmycin Salinomycin sodium salt Eravacycline HCl Halazone T.cruzi-IN-1 Amorolfine HCL

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Calculation results:

Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

Note:

Be sure to add the solvent(s) in order. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Tigecycline 220620-09-7 Autophagy Microbiology/Virology Antibiotic Antibacterial ribosome GAR936 Bacterial Inhibitor GAR-936 GAR 936 inhibit inhibitor

Products are chemical reagents for research use only and are not intended for human use. We do not sell to patients.