Search Result

Search Results for " ofe "

Targets

218

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T3496	Buprofezin	NNI 750,Applaud,Buprofezine	Reactive Oxygen Species
	Buprofezin (Applaud) is an insecticide used for control of insect pests such as mealybugs, leafhoppers and whitefly on vegetable crops.		Reactive Oxygen Species
T1470	Fexofenadine hydrochloride	Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,Telfast,Fexofenadine HCl,Allegra,MDL 16455A	Histamine Receptor
	Fexofenadine hydrochloride (Terfenidine carboxylate hydrochloride) is a second generation antihistamine that is used for the treatment of allergic rhinitis, angioedema and chronic urticaria.		Histamine Receptor
T6540	Ibuprofen Lysine	Neoprofen	COX
	Ibuprofen Lysine (Neoprofen) is a non-steroidal anti-inflammatory drug.		COX
T12987	Spirodiclofen	BAJ-2740	Parasite
	Spirodiclofen (BAJ-2740) is a selective, non-systemic acaricide from the new chemical class of tetronic acid derivatives,with no cross resistance to currently available acaricides and with additional insecticidal propert...		Parasite
T8364	Mebrofenin	SQ 26962	Others
	Mebrofenin (SQ 26962) is available as a ready to use the kit for radio-labeling with Tc-99m.Technetium Tc 99m Mebrofenin is a diagnostic radiopharmaceutical composed of diisopropyl-iminodiacetic acid (DISIDA) attached to...		Others
T1555	Diclofenac sodium	GP 45840	Apoptosis , COX
	Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.		Apoptosis , COX
T22437	Tazofelone	LY-213829	Others
	Tazofelone (LY-213829) is a NSAID used for the treatment of inflammatory bowel disease.		Others
T39280	Nitrofen		Others
	Nitrofen is a selective contact herbicide. Nitrofen is a protoporphyrinogen oxidase and retinal dehydrogenase inhibitor.		Others
T8630	Baclofen hydrochloride	4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride	GABA Receptor
	Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe...		GABA Receptor
T29842	Alclofenac	W 7320,MY 101,BRN 2116510,W-7320,W7320	Others
	Alclofenac (W-7320) has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism.		Others
T1065	Baclofen	Lioresal	GABA Receptor
	Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp...		GABA Receptor
T6053	Turofexorate Isopropyl	XL335,FXR-450,WAY-362450	FXR , Autophagy
	Turofexorate Isopropyl (XL335) is a potent, selective, and orally bioavailable FXR agonist with EC50 of 4 nM		FXR , Autophagy
T7436	Cilofexor		FXR , Autophagy
	Cilofexor inhibits binding of a synthetic peptide, Cilofexor is a farnesoid X receptor (FXR) agonist.		FXR , Autophagy
T0643	Diclofenac Amide		Others
	Diclofenac Amide is used as a intermediates of Diclofenac.		Others
T16022	Arhalofenate	JNJ 39659100,MBX 102	PPAR
	Arhalofenate (JNJ 39659100) is a selective partial agonist of peroxisome proliferator-activated receptor PPARγ. It is used for the treatment of type 2 diabetes.		PPAR
T4466	Pitofenone hydrochloride	Baralgin Ketone Hydrochloride,Pitophenone hydrochloride	AChE
	Pitofenone hydrochloride (Pitophenone hydrochloride), a spasmolytic compound, inhibits the acetylcholinesterase (AChE) activity from bovine erythrocytes and from electric eel with Kis of 36 and 45 μM, respectively.		AChE
T0839L	S-(+)-Ketoprofen	RP-19583,Dexketoprofen,(S)-(+)-Ketoprofen,(S)-Ketoprofen	COX
	S-(+)-Ketoprofen ((S)-(+)-Ketoprofen) works by blocking the action of a substance in the body called cyclo-oxygenase. It belongs to a class of medicines called non-steroidal anti-inflammatory drugs (NSAIDs). Cyclo-oxygen...		COX
T0463L	Loxoprofen sodium	CS-600,CS600,Loxoprofen,CS 600	COX
	Loxoprofen sodium (CS-600) is an effective and oral sodium inhibitor of COX-1 and COX-2 with IC50 of 6.5 and 13.5 μM, respectively. Loxoprofen sodium works by reducing the synthesis of prostaglandins from arachidonic aci...		COX
T0260	Meclofenamic acid sodium	Meclofenamate Sodium,Movens,Meclomen,Meclonax	Gap Junction Protein , COX
	Meclofenamic acid sodium (Movens), a non-steroidal anti-inflammatory agent, has properties of antipyretic and antigranulation activities. It also inhibits prostaglandin biosynthesis.		Gap Junction Protein , COX
T2553	Etofenamate		COX
	Etofenamate is a non-steroidal anti-inflammatory drug (NSAID) used for the treatment of joint and muscular pain.		COX
T6470	Diclofenac Potassium	CGP-45840B,Cataflam,Voltfast	Apoptosis , Others , COX
	Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.		Apoptosis , Others , COX
T1325	Carprofen	Ridamyl,Imadyl,Rimadyl	FAAH , COX , Autophagy
	Carprofen (Ridamyl) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic activities.		FAAH , COX , Autophagy
T0159	Pranoprofen	Pyranoprofen	Apoptosis , COX , PGE Synthase , Prostaglandin Receptor
	Pranoprofen (Pyranoprofen) (INN) is a non-steroidal anti-inflammatory drug used in ophthalmology.		Apoptosis , COX , PGE Synthase , Prostaglandin Receptor
T6476	Dofetilide	UK 68789,UK-68798,Tikosyn	Potassium Channel
	Dofetilide (UK 68789) is a sulfonamide class III antiarrhythmic agent and potassium channel blocker. Dofetilide selectively blocks cardiac ion channels of the rapid component of the delayed rectifier potassium current Ik...		Potassium Channel
T7363	Ibuprofen Piconol	U75630	Others
	Ibuprofen Piconol (U75630) is a non-steroidal, anti-inflammatory (NSAID) agent for the topical relief of primary thermal burns and sunburns.Ibuprofen piconol is a Pyridyl ester of ibuprofen.		Others
T22307	Diclofenac Epolamine	diclofenac hydroxyethylpyrrolidine,DHEP,DIEP	Others
	Diclofenac Epolamine (DHEP) is a non-steroidal anti-inflammatory agent (NSAID) with analgesic and antipyretic actions.		Others
T7341	Diclofensine	Ro 8-4650	Dopamine Receptor , Monoamine Transporter
	Diclofensine (Ro 8-4650) inhibits the uptake of serotonin, noradrenaline and dopamine.		Dopamine Receptor , Monoamine Transporter
T34268	Raxofelast	IRFI016,IRFI-016,IRFI 016
	Raxofelast (IRFI-016) is a hydrophilic, non-systemic, vitamin-like antioxidant that reduces ischemia-reperfusion injury in testis. Raxofelast is a good candidate compound for stopping oxidative stress after acute testicu...
T68025	Zoliprofen		Others
	Zoliprofen is a potent and orally available non-steroidal anti-inflammatory agent with anti-inflammatory, antipyretic and analgesic activity, and inhibits carobolin, mycobacterium, and knife-ball protein A-induced rat pa...		Others
T32845	Lofendazam	Bu 1014
	Lofendazam (Bu 1014) is a benzodiazepine derivative that has sedative and anxiolytic effects.
T35180	Ximoprofen	Ximoprofeno,Ximoprofenum	Others
	Ximoprofen is a novel anti-inflammatory compound for the study of spondylitis.		Others
T11340	Furprofen		Prostaglandin Receptor
	Furprofen, a non-steroidal anti-inflammatory drug (NSAID), exerts its effects by inhibiting the synthesis of prostaglandin (PGE). This compound demonstrates analgesic properties and can be conveniently administered orall...		Prostaglandin Receptor
T4189	4-Oxofenretinide	3-Keto fenretinide	cell cycle arrest
	4-Oxofenretinide (3-Keto fenretinide) , a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis.		cell cycle arrest
T6568	Licofelone	ML-3000	Apoptosis , Lipoxygenase , COX
	Licofelone (ML-3000) is a dual COX/LOX inhibitor potentially for the treatment of osteoarthritis. Licofelone is both an analgesic and an anti-inflammatory. Inhibition of 5-LOX may reduce the gastrointestinal toxicity ass...		Apoptosis , Lipoxygenase , COX
T11071	Dofequidar fumarate	MS-209	P-gp
	Dofequidar fumarate (MS-209)(MS-209 fumarate), a quinoline-based compound administered orally, is known for counteracting multidrug resistance (MDR) through the inhibition of ABCB1/P-glycoprotein (P-gp) and ABCC1/MDR-ass...		P-gp
T25956	Piketoprofen	Calmatel	Others
	Piketoprofen (Calmatel) is a topical nonsteroidal anti-inflammatory agent.		Others
T7710	MOFEBUTAZONE		Others
	Mofebutazone inhibits the immunological release of prostaglandins as well as leukotrienes.		Others
T4384	Halofenozide		Others
	Halofenozide is an ecdysteroid agonist and used as a pesticide.		Others
T14546	Bermoprofen	AD-1590,AJ-1590	Others
	Bermoprofen (AD-1590) is an orally active non-steroidal anti-inflammatory compound with anti-inflammatory and analgesic activity used in the study of gastric ulcers.		Others
T1394	Ibuprofen	Brufen,(±)-Ibuprofe,Motrin,Advil	COX
	Ibuprofen (Advil) is a propionic acid derivate and nonsteroidal anti-inflammatory drug (NSAID) with anti-inflammatory, analgesic, and antipyretic effects. Ibuprofen inhibits the activity of cyclo-oxygenase I and II, resu...		COX
T1185	Rofecoxib	MK 966,MK-0966	COX
	Rofecoxib (MK 966) binds to and inhibits the enzyme cyclooxygenase-2 (COX-2), resulting in an inhibition of the conversion of arachidonic acid to prostaglandins. Rofecoxib is a synthetic, nonsteroidal derivative of pheny...		COX
T0713	Drofenine hydrochloride	Hexahydroadiphenine hydrochloride	AChE
	Drofenine hydrochloride (Hexahydroadiphenine hydrochloride) is an effective competitive inhibitor of BChE (Ki value: 3 uM).		AChE
T5460	Mofezolac		COX
	Mofezolac (formerly known as Disopain or N-22) is a highly selective COX-1 (cyclooxygenase-1) inhibitor with COXs selectivity index > 6000		COX
T17309	(R)-(-)-Ibuprofen	levibuprofen,(R)-Ibuprofen	NF-κB
	(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects.		NF-κB
T7745	Diclofensine hydrochloride	Ro 8-4650 hydrochloride	Others , Dopamine Receptor
	Diclofensine hydrochloride (Ro 8-4650 hydrochloride) is a Novel Antidepressant, on Peripheral Adrenergic Function		Others , Dopamine Receptor
T4994	Tocofersolan	Vitamin E-TPGS,Tocophersolan,TPGS,D-α-Tocopherol polyethylene glycol 1000 succinate,维生素E聚乙二醇琥珀酸酯	Others
	Tocofersolan (TPGS) is a polyethylene glycol derivative of α-tocopherol and synthetic water-soluble version of Tocopherol. Tocofersolan is an oral treatment of vitamin E deficiency due to digestive malabsorption in pedia...		Others
T68093	Lobuprofen		COX
	Lobuprofen is a small molecule COX inhibitor that is used to treat neurological disorders.		COX
T0196	Diclofenac	Diclofenacum,Voltaren	Apoptosis , COX
	Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a...		Apoptosis , COX
T0463	Loxoprofen	Loxoprofene,Loxoprofeno,Koloxo	COX
	Loxoprofen (Koloxo) is an anti-inflammatory non-steroidal medicine.		COX
T0291	Flurbiprofen	dl-Flurbiprofen	Apoptosis , COX , MRP
	Flurbiprofen (dl-Flurbiprofen) is an anti-inflammatory analgesic and antipyretic of the phenylalkynoic acid series. It has been shown to reduce bone resorption in periodontal disease by inhibiting CARBONIC ANHYDRASE.		Apoptosis , COX , MRP

Compounds

Buprofezin

T3496

Synonym: NNI 750,Applaud,Buprofezine

Target: Reactive Oxygen Species

Fexofenadine hydrochloride

T1470

Synonym: Terfenidine carboxylate hydrochloride,MDL-16455 hydrochloride,Telfast,Fexofenadine HCl,Allegra,MDL 16455A

Target: Histamine Receptor

Target: Apoptosis, COX

Baclofen hydrochloride

T8630

Synonym: 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride

Target: GABA Receptor

Alclofenac

T29842

Synonym: W 7320,MY 101,BRN 2116510,W-7320,W7320

Target: GABA Receptor

Turofexorate Isopropyl

T6053

Synonym: XL335,FXR-450,WAY-362450

Target: FXR, Autophagy

Cilofexor

T7436

Synonym:

Target: FXR, Autophagy

Synonym: JNJ 39659100,MBX 102

Target: PPAR

Pitofenone hydrochloride

T4466

Synonym: Baralgin Ketone Hydrochloride,Pitophenone hydrochloride

Target: AChE

S-(+)-Ketoprofen

T0839L

Synonym: RP-19583,Dexketoprofen,(S)-(+)-Ketoprofen,(S)-Ketoprofen

Target: COX

Loxoprofen sodium

T0463L

Synonym: CS-600,CS600,Loxoprofen,CS 600

Target: COX

Meclofenamic acid sodium

T0260

Synonym: Meclofenamate Sodium,Movens,Meclomen,Meclonax

Target: Gap Junction Protein, COX

Synonym: CGP-45840B,Cataflam,Voltfast

Target: Apoptosis, Others, COX

Carprofen

T1325

Synonym: Ridamyl,Imadyl,Rimadyl

Target: FAAH, COX, Autophagy

Pranoprofen

T0159

Synonym: Pyranoprofen

Target: Apoptosis, COX, PGE Synthase, Prostaglandin Receptor

Dofetilide

T6476

Synonym: UK 68789,UK-68798,Tikosyn

Target: Potassium Channel

Synonym: diclofenac hydroxyethylpyrrolidine,DHEP,DIEP

Target: Dopamine Receptor, Monoamine Transporter

Raxofelast

T34268

Synonym: IRFI016,IRFI-016,IRFI 016

Synonym: Ximoprofeno,Ximoprofenum

Target: Prostaglandin Receptor

4-Oxofenretinide

T4189

Synonym: 3-Keto fenretinide

Target: cell cycle arrest

Licofelone

T6568

Synonym: ML-3000

Target: Apoptosis, Lipoxygenase, COX

Synonym: AD-1590,AJ-1590

Target: Others

Ibuprofen

T1394

Synonym: Brufen,(±)-Ibuprofe,Motrin,Advil

Target: COX

Rofecoxib

T1185

Synonym: MK 966,MK-0966

Target: COX

Drofenine hydrochloride

T0713

Synonym: Hexahydroadiphenine hydrochloride

Synonym: levibuprofen,(R)-Ibuprofen

Target: NF-κB

Diclofensine hydrochloride

T7745

Synonym: Ro 8-4650 hydrochloride

Target: Others, Dopamine Receptor

Tocofersolan

T4994

Synonym: Vitamin E-TPGS,Tocophersolan,TPGS,D-α-Tocopherol polyethylene glycol 1000 succinate,维生素E聚乙二醇琥珀酸酯

Synonym: Diclofenacum,Voltaren

Target: Apoptosis, COX

Loxoprofen

T0463

Synonym: Loxoprofene,Loxoprofeno,Koloxo

Target: COX

Flurbiprofen

T0291

Synonym: dl-Flurbiprofen

Target: Apoptosis, COX, MRP

Cat No.	Product Name	Synonyms	Targets
TN1145	Isofebrifugine		Parasite
	Isofebrifugine is an alkaloid from the plant Changshan of the Saxifrage family with antimalarial and anti-infectious activity.		Parasite
T2889	Isoferulic acid	Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate	Influenza Virus , Adrenergic Receptor
	Isoferulic acid (Hesperetate) exhibits hypoglycemic properties.		Influenza Virus , Adrenergic Receptor
T0558	Dihydroferulic acid	Dihydroconiferylic acid,Hydroferulic acid	Others
	Dihydroferulic acid is used as the intermediates of perfume and essence.		Others
T9790	Lactoferrin	Lactoferrin (Bovine)	Endogenous Metabolite
	Lactoferrin is secreted by mammals and displays extensive biological effects including boosting the cold tolerance of a well-applied probiotic strain.		Endogenous Metabolite
T4394	Methyl Isoferulate		Others
	This product is isolated and purified from the leaves of Phyllostachys heterocycla		Others
T6293	Mycophenolate Mofetil	TM-MMF,RS 61443	Apoptosis , Dehydrogenase , Drug Metabolite
	Mycophenolate Mofetil (TM-MMF), an immunosuppressive agent, is the 2-morpholinoethyl ester of mycophenolic acid (MPA), and an inhibitor of inosine monophosphate dehydrogenase (IMPDH).		Apoptosis , Dehydrogenase , Drug Metabolite
T81099	Staphyloferrin A
	Staphyloferrin A, a siderophore, can be utilized in conjunction with antibiotics to investigate drug-resistant bacteria implicated in skin diseases [1].
T10072	2-Hydroxy Ibuprofen	(±)-2-Hydroxy Ibuprofen	Others
	2-Hydroxy Ibuprofen is a metabolite of Ibuprofen. Ibuprofen is an anti-inflammatory inhibitor targeting COX-1/COX-2 (IC50s: 13 μM/370 μM).		Others
T40988	(+)-Norlirioferine
	(+)-Norlirioferine is an alkaloid compound that exhibits cell growth inhibitory effects on macrophages and VERO cells.
TN3662	Cinnamyl isoferulate		Others
	Cinnamyl isoferulate is a natural product of Populus, Salicaceae. The catalog number is TN3662 and the CAS number is 115610-31-6. Cinnamyl isoferulate can be used as a reference standard.		Others

Natural Products

Synonym: Isoferulate,Hesperetic acid,3-Hydroxy-4-methoxycinnamic acid,Hesperetate

Target: Influenza Virus, Adrenergic Receptor

Dihydroferulic acid

T0558

Synonym: Dihydroconiferylic acid,Hydroferulic acid

Target: Others

Lactoferrin

T9790

Synonym: Lactoferrin (Bovine)

Target: Endogenous Metabolite

Mycophenolate Mofetil

T6293

Synonym: TM-MMF,RS 61443

Target: Apoptosis, Dehydrogenase, Drug Metabolite

Synonym: (±)-2-Hydroxy Ibuprofen

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-04142	RANK/TNFRSF11A Protein, Human, Recombinant (hFc)	Human	HEK293
	TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-05514	RANK/TNFRSF11A Protein, Human, Recombinant (mFc)	Human	HEK293
	TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPY-04157	RANK/TNFRSF11A Protein, Human, Recombinant (His)	Human	HEK293
	TNFRSF11A is a member of the TNF-receptor superfamily. In mouse, it is also known as CD265. TNFRSF11A contains 4 TNFR-Cys repeats and is widely expressed with high levels in skeletal muscle, thymus, liver, colon, small i...
TMPJ-00349	RANK/TNFRSF11A Protein, Human, Recombinant (aa 30-212, His)	Human	Human Cells
	Receptor Activator of Nuclear Factor κ B (RANK), also known as CD265, TRANCE Receptor or TNFRSF11A, is member of the tumor necrosis factor receptor (TNFR) molecular superfamily. RANK is the receptor for RANK-Ligand (RANK...
TMPH-01301	Erythroferrone Protein, Human, Recombinant (His & SUMO)	Human	E. coli
	Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase...
TMPY-02728	Lactoferrin/LTF Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Lactotransferrin, also known as Lactoferrin, Talalactoferrin, and LTF, is a secreted protein that belongs to the transferrin family. Transferrins are iron binding transport proteins that can bind two Fe3+ions in associat...
TMPY-02188	Lactoferrin/LTF Protein, Human, Recombinant (His)	Human	HEK293
	Lactotransferrin, also known as Lactoferrin, Talalactoferrin, and LTF, is a secreted protein that belongs to the transferrin family. Transferrins are iron binding transport proteins that can bind two Fe3+ions in associat...
TMPH-02646	Erythroferrone Protein, Mouse, Recombinant (His)	Mouse	Yeast
	Iron-regulatory hormone that acts as an erythroid regulator after hemorrhage: produced by erythroblasts following blood loss and mediates suppression of hepcidin (HAMP) expression in the liver, thereby promoting increase...