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Baclofen hydrochloride

Catalog No. T8630 CAS 28311-31-1

Synonyms: 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride

Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Baclofen hydrochloride Chemical Structure

Baclofen hydrochloride, CAS 28311-31-1

Pack Size	Availability	Price/USD
1 mg	In stock	$ 133.00
2 mg	In stock	$ 197.00
5 mg	In stock	$ 297.00
10 mg	In stock	$ 453.00
25 mg	In stock	$ 747.00
50 mg	In stock	$ 1,050.00
100 mg	In stock	$ 1,420.00

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Purity: 99.83%

Biological Description

Chemical Properties

Storage & Solubility Information

Description

Synonyms	4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride
Molecular Weight	250.122
Formula	C10H13Cl2NO2
CAS No.	28311-31-1

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Slightly soluble

References and Literature

1. Wendell, Lake, Hamid, et al. Intrathecal Baclofen Infusion for the Treatment of Movement Disorders.[J]. Neurosurgery Clinics of North America, 2019. 2. Silvia, Minozzi, Rosella, et al. Baclofen for alcohol use disorder.[J]. Cochrane Database of Systematic Reviews, 2018.

Related compound libraries

This product is contained In the following compound libraries：

Anti-Cancer Approved Drug Library Anti-Cancer Drug Library Anti-Neurodegenerative Disease Compound Library Drug Repurposing Compound Library FDA-Approved Drug Library Antidepressant Compound Library Neurotransmitter Receptor Compound Library Approved Drug Library Bioactive Compounds Library Max FDA-Approved & Pharmacopeia Drug Library

Related Products

Related compounds with same targets

(-)-Securinine γ-Aminobutyric acid (-)-Corlumine Saclofen CGP52432 Propanidid Primidone U-89843A

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO (Master liquid concentration mg/mL)，Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug.

Method for preparing in vivo formulation：Take μL DMSO master liquid, next add μL PEG300， mix and clarify, next add μL Tween 80，mix and clarify, next add μL ddH₂O, mix and clarify.

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What is the mass of compound required to make a 10 mM stock solution in 10 ml of water given that the molecular weight of the compound is 197.13 g/mol?
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.

Keywords

Baclofen hydrochloride 28311-31-1 Membrane transporter/Ion channel Neuroscience GABA Receptor Gamma-aminobutyric acid Receptor GABA γ-Aminobutyric acid Receptor spasticity γ-aminobutyric acid Baclofen Lipophilic GABABR bbb inhibit blood brain barrier 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride Inhibitor orally Baclofen Hydrochloride inhibitor

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