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Alclofenac

Catalog No. T29842   CAS 22131-79-9
Synonyms: W 7320, MY 101, BRN 2116510, W-7320, W7320

Alclofenac (W-7320) has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism.

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Alclofenac Chemical Structure
Alclofenac, CAS 22131-79-9
Pack Size Availability Price/USD Quantity
2 mg In stock $ 55.00
5 mg In stock $ 78.00
10 mg In stock $ 112.00
25 mg In stock $ 197.00
50 mg In stock $ 289.00
100 mg In stock $ 434.00
1 mL * 10 mM (in DMSO) In stock $ 81.00
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Alclofenac (W-7320) has a significant effect on the acute phase protein response and the degree of L-tryptophan binding to plasma protein and can be used in the treatment of patients with chronic rheumatism.
Synonyms W 7320, MY 101, BRN 2116510, W-7320, W7320
Molecular Weight 226.66
Formula C11H11ClO3
CAS No. 22131-79-9

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 14 mg/mL (61.77 mM)

TargetMolReferences and Literature

1. Knights KM, Winner LK, Elliot DJ, Bowalgaha K, Miners JO. Aldosterone glucuronidation by human liver and kidney microsomes and recombinant UDP-glucuronosyltransferases: inhibition by NSAIDs. Br J Clin Pharmacol. 2009 Sep;68(3):402-12. doi: 10.1111/j.1365-2125.2009.03469.x. PubMed PMID: 19740398; PubMed Central PMCID: PMC2766480. 2. Grimes DA, Hubacher D, Lopez LM, Schulz KF. Non-steroidal anti-inflammatory drugs for heavy bleeding or pain associated with intrauterine-device use. Cochrane Database Syst Rev. 2006 Oct 18;(4):CD006034. Review. PubMed PMID: 17054271. 3. Selinsky BS, Gupta K, Sharkey CT, Loll PJ. Structural analysis of NSAID binding by prostaglandin H2 synthase: time-dependent and time-independent inhibitors elicit identical enzyme conformations. Biochemistry. 2001 May 1;40(17):5172-80. PubMed PMID: 11318639. 4. Fillet M, Bechet I, Piette V, Crommen J. Separation of nonsteroidal anti-inflammatory drugs by capillary electrophoresis using nonaqueous electrolytes. Electrophoresis. 1999 Jul;20(9):1907-15. PubMed PMID: 10445335.

Related compound libraries

This product is contained In the following compound libraries:
Human Metabolite Library Bioactive Compounds Library Max ReFRAME Related Library Bioactive Compound Library Drug-induced Liver Injury (DILI) Compound Library

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Keywords

Alclofenac 22131-79-9 Others BRN-2116510 W 7320 MY101 BRN2116510 MY-101 MY 101 BRN 2116510 W-7320 W7320 inhibitor inhibit

 

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