Powder: -20°C for 3 years | In solvent: -80°C for 1 year
(R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
50 mg | In stock | $ 42.00 | |
100 mg | In stock | $ 59.00 | |
200 mg | In stock | $ 87.00 | |
500 mg | In stock | $ 143.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 96.00 |
Description | (R)-(-)-Ibuprofen ((R)-Ibuprofen) is the R enantiomer of Ibuprofen and inhibits NF-κB activation. (R)-(-)-Ibuprofen has anti-inflammatory and antinociceptive effects. |
In vitro | (R)-(-)-Ibuprofen is involved in pathways of lipid metabolism and is incorporated into triglycerides along with endogenous fatty acids. (R)-(-)-Ibuprofen inhibits NF-κB luciferase activity (IC50: 121.8 μM), weaker than that of S(+)-ibuprofen (IC50, 61.7 μM). (R)-(-)-Ibuprofen (1 μM) significantly decreases NF-κB activation and fully prevents NF-κB induction at 10 μM. Furthermore, (R)-(-)-Ibuprofen (10 mM) has no effect on HSF [1][2]. |
Synonyms | levibuprofen, (R)-Ibuprofen |
Molecular Weight | 206.28 |
Formula | C13H18O2 |
CAS No. | 51146-57-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 45 mg/mL (218.15 mM)
You can also refer to dose conversion for different animals. More
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(R)-(-)-Ibuprofen 51146-57-7 NF-Κb NF-κB levibuprofen (R)-Ibuprofen Ibuprofen inhibitor inhibit