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Lofendazam (Synonyms: Bu 1014)

Name: Lofendazam
Brand: TargetMol
SKU: T32845
Price: 56 USD
Availability: InStock
Rating: 5 (10 reviews)

Catalog No. T32845 Copy Product Info

Purity: 97.28%

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Lofendazam (Bu 1014) is a benzodiazepine derivative that has sedative and anxiolytic effects.

Lofendazam

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Catalog No. T32845

Synonyms Bu 1014

Lofendazam (Bu 1014) is a benzodiazepine derivative that has sedative and anxiolytic effects.

Cas No. 29176-29-2

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Pack Size	Price	USA Stock	Global Stock
1 mg	$56	In Stock	In Stock
5 mg	$133	In Stock	In Stock
10 mg	$202	In Stock	In Stock
25 mg	$330	In Stock	In Stock
50 mg	$453	In Stock	In Stock
100 mg	$622	In Stock	In Stock
200 mg	$833	-	In Stock

For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)

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Custom-made molecule. TargetMol’s expert synthesis team delivers cost-effective solutions. Contact us for inquiries. Committed to serving you.

For research use only—not for human use. No sales to individuals. Use as intended only.

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Batch Information

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Purity:97.28%

Appearance:Solid

Color:White

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COA HNMR HPLC

Product Introduction

Bioactivity

Description	Lofendazam (Bu 1014) is a benzodiazepine derivative that has sedative and anxiolytic effects.
Synonyms	Bu 1014

Chemical Properties

Molecular Weight	272.73
Formula	C₁₅H₁₃ClN₂O
Cas No.	29176-29-2
Smiles	O=C1N(C=2C(NCC1)=CC=C(Cl)C2)C3=CC=CC=C3
Relative Density.	1.276 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 45 mg/mL (165 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.6666 mL	18.3332 mL	36.6663 mL	183.3315 mL
5 mM	0.7333 mL	3.6666 mL	7.3333 mL	36.6663 mL
10 mM	0.3667 mL	1.8333 mL	3.6666 mL	18.3332 mL
20 mM	0.1833 mL	0.9167 mL	1.8333 mL	9.1666 mL
50 mM	0.0733 mL	0.3667 mL	0.7333 mL	3.6666 mL
100 mM	0.0367 mL	0.1833 mL	0.3667 mL	1.8333 mL

Note : The dilution table applies only to solid products. For liquid products, please calculate the stock solution based on the stated concentration and/or density.

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc