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Signaling Pathways Angiogenesis Apoptosis Autophagy Cell Cycle/Checkpoint Chromatin/Epigenetic Cytoskeletal Signaling
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Metabolism Microbiology/Virology Neuroscience NF-Κb oxidation-reduction PI3K/Akt/mTOR signaling Proteases/Proteasome
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Search Result

Search Results for " hdac "

Targets

HDAC HDAC mTOR

327

Compounds

16

Natural Products

16

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T63399L MTOR/HDAC-IN-1 HCl mTOR/HDAC-IN-1 HCl（2815286-02-1 Free base) HDAC , mTOR
mTOR/HDAC-IN-1 HCl is a potent dual inhibitor of mTOR and HDAC with potential anti-inflammatory, anti-proliferative, autophagy and apoptosis-inducing effects for cancer research.
T60082 HDAC-IN-40 HDAC
HDAC-IN-40 is a potent alkoxyamide-based HDAC inhibitor with Ki of 60 nM and 30 nM for HDAC2 and HDAC6, respectively. HDAC-IN-40 had antitumor effects
T8508 HDAC-IN-3 GSK3117391A HDAC
HDAC-IN-3 (GSK3117391A) is a potent histone deacetylase (HDAC) inhibitor, and treatment chronic inflammatory disorders.
T77334 HDAC-IN-57 Apoptosis , HDAC
HDAC-IN-57 is an orally active pan-inhibitor of histone deacetylase (HDAC), inhibiting HDAC1, HDAC2, HDAC6, and HDAC8 with IC50 values of 2.07 nM, 4.71 nM, 2.4 nM, and 107 nM, respectively. HDAC-IN-57 inhibits LSD1 with ...
T2025 HDAC-IN-7 HBI-8000,CS055,Chidamide impurity HDAC
HDAC-IN-7 (HBI-8000) (Chidamide impurity) is an impurity of Chidamide. Chidamide is a potent and orally bioavailable inhibitor of HDAC enzymes class I (HDAC1/2/3) and class IIb (HDAC10).
T73181 HDAC-IN-51 HDAC
HDAC-IN-51 is an HDAC inhibitor.
T10245 ACY-957 HDAC Inhibitor C001 HDAC
ACY-957 (HDAC Inhibitor C001) is an orally active and selective inhibitor of HDAC1 and HDAC2 (IC50s: 7 nM, 18 nM, and 1300 nM against HDAC1/2/3) and shows no inhibition on HDAC4/5/6/7/8/9.
T67878 HDAC-IN-52 HDAC
HDAC-IN-52 is a pyridine-containing HDAC inhibitor that inhibits HDAC1, HDAC2, HDAC3 and HDAC10 with IC50s of 0.189, 0.227, 0.440 and 0.446 μM, respectively. HDAC-IN-52 can be used in cancer research.
T25489 HDAC-IN-20 HDACIN20,HDAC-inhibitor-20,HDAC inhibitor 20
HDAC-IN-20 is used as an HDAC inhibitor that acts by preventing HDAC-mediated diseases.
T3661 Citarinostat ACY241,HDAC-IN-2 HDAC
ACY-241, also known as Citarinostat (ACY241), is a potent, selective and orally available histone deacetylase (HDAC) inhibitor, with potential antineoplastic activity. Upon oral administration, ACY-241 inhibits the activ...
T2078 Fimepinostat CUDC-907,PI3K/HDAC Inhibitor,CUDC 907 Apoptosis , PI3K , HDAC
Fimepinostat (CUDC 907) is an orally bioavailable inhibitor of both phosphoinositide 3-kinase (PI3K) class I and pan-histone deacetylase (HDAC) enzymes, with potential antineoplastic activity. Upon oral administration, C...
T39990 HDAC-IN-26
HDAC-IN-26 is a highly selective class I HDAC inhibitor with an EC 50 value of 4.7 nM.
T6392 AR42 OSU-HDAC42,AR-42,AR 42,HDAC-42 HDAC
AR42 (OSU-HDAC42) is an HDAC inhibitor (IC50: 30 nM).
T11543 HDAC-IN-5 HDAC
HDAC-IN-5 is a histone deacetylase (HDAC) inhibitor.
T11542 HDAC-IN-4 HDAC
HDAC-IN-4 is a selective HDAC6 and HDAC10 inhibitor (pIC50s: 7.2 and 6.8 in BRET assay) with antitumoral activity.
T12455 PI3K/HDAC-IN-1 PI3K
PI3K/HDAC-IN-1 is a potent PI3K and HDAC dual inhibitor(IC50s of 8.1 nM and 1.4 nM, respectively).
T62708 HDAC-IN-37
HDAC-IN-37 is a potent inhibitor of HDAC, acting on HDAC1 (IC50: 0.0551 μM), HDAC3 (IC50: 1.24 μM), HDAC8 (IC50: 0.948 μM) and HDAC6 (IC50: 34.2 μM). HDAC-IN-37 is able to slowly induce histone acetylation. HDAC-IN-37 pr...
T61916 HDAC-IN-35
HDAC-IN-35 (Compound 14) is an effective and selective inhibitor of VEGFR-2 and HDAC, with IC50 values of 13.2 and 0.166 μM for VEGFR-2 and HDAC6, respectively.
T73179 HDAC-IN-50
HDAC-IN-50, a potent, orally active inhibitor targeting both FGFR (Fibroblast Growth Factor Receptor) and HDAC (Histone Deacetylase), exhibits IC50 values of 0.18, 1.2, 0.46, 1.4, 1.3, 1.6, 2.6, 13 nM for FGFR1, FGFR2, F...
T74783 HDAC-IN-53 HDAC
HDAC-IN-53 is an orally active, selective inhibitor of HDAC1-3, demonstrating IC50 values of 47 nM, 125 nM, and 450 nM, respectively. It exhibits no inhibitory effects on class II HDACs (HDAC4, 5, 6, 7, 9; IC50 >10 μM). ...
T62545 HDAC-IN-43
HDAC-IN-43 is a potent HDAC 1/3/6 inhibitor with IC50 values of 82 nM for HDAC 1, 45 nM for HDAC 3, and 24 nM for HDAC 6. HDAC-IN-43 is a weak PI3K/mTOR inhibitor with IC50 values of 3.6 μM for PI3K and 3.7 μM for mTOR. ...
T63803 HDAC-IN-44
HDAC-IN-44 is an HDAC inhibitor (IC50: 61.2 nM) with strong anti-cancer effects.
T79003 HDAC ligand-1 HDAC
HDAC ligand-1 is a synthetic precursor utilized in the production of PROTAC-based HDAC degraders [1].
T61954 HDAC-IN-29
HDAC-IN-29 (compound 13b) is a potent pan- HDAC inhibitor with antitumor activity.
T72012 HDAC-IN-6
HDAC-IN-6 is an HDAC inhibitor, targeting HDAC2, HDAC3, HDAC4, HDAC5, HDAC7, HDAC8, and HDAC9.
T62006 HDAC-IN-30
HDAC-IN-30 is a multi-target HDAC inhibitor. HDAC-IN-30 inhibits HDAC1 (IC50 =13.4 nM), HDAC2 (IC50 =28.0 nM), HDAC3 (IC50 =9.18 nM), HDAC6 (IC50 =42.7 nM), HDAC8 (IC50 =131 nM). HDAC-IN-30 shows potent antitumor efficac...
T62649 HDAC-IN-34
HDAC-IN-34 (compound 27) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.022 μM) and HDAC6 (IC50: 0.45 μM). HDAC-IN-34 can bind to DNA and cause DNA damage. HDAC-IN-34 exhibits a significant anti-proliferative ...
T63416 HDAC-IN-39
HDAC-IN-39 is a potent inhibitor of HDAC and is able to act on HDAC1, HDAC2 and HDAC3 with IC50 values of 1.07 μM, 1.47 μM and 2.27 μM, respectively. HDAC-IN-39 induces cell cycle arrest in G2/M phase and also significan...
T73167 HDAC-IN-49
HDAC-IN-49 is a potent, non-selective inhibitor of HDAC (HDAC), demonstrating IC50 values of 13 nM for HDAC1, 14 nM for HDAC2, 21 nM for HDAC3, 1880 nM for HDAC4, and 10 nM for HDAC6. This compound exhibits significant a...
T61630 HDAC-IN-42
HDAC-IN-42 (compound 14f) is a highly potent and selective inhibitor of histone deacetylase (HDAC) enzymes, with IC50 values of 0.19 μM for HDAC1 and 4.98 μM for HDAC6. It exhibits remarkable anticancer properties and in...
T61209 HDAC-IN-27
HDAC-IN-27 is a potent and orally active inhibitor of HDAC Class I (0.43 nM - 3.01 nM for HDAC1-3). HDAC-IN-27 shows activity against anti-acute myeloid leukemia (AML).
T79541 HDAC-IN-61 HDAC
HDAC-IN-61 (compound 12k) is a potent, orally active inhibitor of histone deacetylase (HDAC) with anticancer activity, exhibiting an IC50 of 30 nM against Bel-7402 cells, and is utilized for cancer research [1].
T79371 HDAC-IN-62 Autophagy
HDAC-IN-62 (Compound 5), an HDAC inhibitor, exhibits IC50 values of 0.78, 1.0, and 1.2 μM for HDAC6, HDAC8, and HDAC11, respectively. This compound suppresses microglial activation via autophagy induction and reduces nit...
T78766 HDAC-IN-59 HDAC
HDAC-IN-59 (compound 13a), a potent histone deacetylase (HDAC) inhibitor, enhances intracellular reactive oxygen species (ROS) production, induces DNA damage, arrests the cell cycle at the G2/M phase, and triggers the mi...
T62072 HDAC-IN-47
HDAC-IN-47 is an orally active histone deacetylase (HDAC) inhibitor with IC50 values of 19.75 nM, 57.8 nM, 40.27 nM, 5.63 nM and 302.73 nM for HDAC1, HDAC2, HDAC3, HDAC6 and HDAC8, respectively. HDAC-IN-47 can block the ...
T78767 HDAC-IN-60 HDAC
HDAC-IN-60 (compound 21a), a potent histone deacetylase (HDAC) inhibitor, promotes intracellular reactive oxygen species (ROS) production, induces DNA damage, arrests the cell cycle at the G2/M phase, and triggers mitoch...
T61248 HDAC-IN-32
HDAC-IN-32 is a highly effective HDAC inhibitor presenting IC50 values of 5.2, 11, and 28 nM for HDAC1, HDAC2, and HDAC6, respectively. This compound demonstrates notable anti-proliferative properties against tumor cells...
T78920 HDAC-IN-58 HDAC
HDAC-IN-58, a selective HDAC6 inhibitor, exhibits potent inhibitory activity with an IC50 of 2.06 nM, rendering it suitable for research into chronic neurodegenerative and psychiatric disorders [1].
T63696 HDAC-IN-9
HDAC-IN-9 is a potent and selective dual inhibitor of tubulin and HDAC. HDAC-IN-9 exhibits inhibitory effects on the invasion and migration of A549 cells. HDAC-IN-9 exhibits potent anti-tumor and anti-angiogenic activiti...
T62799 HDAC-IN-28
HDAC-IN-28 is a novel inhibitor of HDAC that significantly inhibits tumour growth and metastasis.
T63791 HDAC-IN-36
HDAC-IN-36 is an orally active HDAC (histone deacetylase) inhibitor with an IC50 value of 11.68 nM for HDAC6. HDAC-IN-36 induces apoptosis, autophagy and inhibits migration. HDAC-IN-36 exhibits antitumor and antimetastat...
T62514 HDAC-IN-46
HDAC-IN-46 (compound 12c) is a potent inhibitor of HDAC that acts on HDAC1 (IC50: 0.21 μM) and HDAC6 (IC50: 0.021 μM). HDAC-IN-46 upregulates p-p38 and downregulates Bcl-xL and cyclin D1 in MDA-MB-231 cells. HDAC-IN-46 c...
T62920 HDAC-IN-38
HDAC-IN-38 is a potent inhibitor of HDAC. HDAC-IN-38 has similar micromolar inhibitory effects on HDAC1, 2, 3, 5, 6 and 8, and also increases histone acetylation levels (H3K14 or H4K5). HDAC-IN-38 increases cerebral bloo...
T62644 HDAC-IN-41
HDAC-IN-41 (Compound 7c) is an orally active, selective class I HDAC inhibitor that acts on HDAC1 (IC50: 0.62 μM), HDAC2 (IC50: 1.46 μM) and HDAC3 (IC50: 0.62 μM). HDAC-IN-41 shows NO-releasing activity.
T62109 HDAC-IN-31
HDAC-IN-31 is a selective, potent, orally active HDAC inhibitor that acts on HDAC1 (IC50: 84.90 nM), HDAC2 (IC50: 168.0 nM), HDAC3 (IC50: 442.7 nM), HDAC8 (IC50>10000 nM). HDAC-IN-31 has good anti-tumour effects. HDAC-IN...
T63422 HDAC-IN-45
HDAC-IN -45, a small molecule HDAC inhibitor, was able to form hydrogen bonds with Y303 residues and exhibited anticancer effects. HDAC-IN-45 significantly inhibited HDAC1, HDAC2 and HDAC3 subtypes with their IC50 values...
T61429 HDAC-IN-33
HDAC-IN-33 is a highly potent HDAC inhibitor, effectively inhibiting HDAC1, HDAC2, and HDAC6 with IC50 values of 24, 46, and 47 nM, respectively. This compound demonstrates significant antiproliferation activity against ...
T78818 HDAC-IN-63
HDAC-IN-63 (Compound 63) is a dual FLT3/HDAC inhibitor with IC50 values of 0.844 nM for FLT3 and 30.0 nM for HDAC1. It effectively suppresses MV4-11 cell proliferation with an IC50 of 92 nM, induces apoptosis, and arrest...
T78532 HDAC-IN-55 Others
HDAC-IN-55(8j) is a small-molecule inhibitor that enhances E-cadherin expression and suppresses cancer cell proliferation [1].
T79674 HDAC-IN-64 HDAC
HDAC-IN-64 (Compound 13), an HDAC inhibitor, demonstrates potent inhibition of HDAC4/5/6/7/9 with IC50 values of 24, 45, 85, 31, and 37 nM, respectively. It exhibits anti-proliferative and anti-migration effects on prost...

Compounds

mTOR/HDAC-IN-1 HCl
T63399L
Synonym: mTOR/HDAC-IN-1 HCl（2815286-02-1 Free base)
Target: HDAC, mTOR
HDAC-IN-40
T60082
Synonym:
Target: HDAC
HDAC-IN-3
T8508
Synonym: GSK3117391A
Target: HDAC
HDAC-IN-57
T77334
Synonym:
Target: Apoptosis, HDAC
HDAC-IN-7
T2025
Synonym: HBI-8000,CS055,Chidamide impurity
Target: HDAC
HDAC-IN-51
T73181
Synonym:
Target: HDAC
ACY-957
T10245
Synonym: HDAC Inhibitor C001
Target: HDAC
HDAC-IN-52
T67878
Synonym:
Target: HDAC
HDAC-IN-20
T25489
Synonym: HDACIN20,HDAC-inhibitor-20,HDAC inhibitor 20
Target:
Citarinostat
T3661
Synonym: ACY241,HDAC-IN-2
Target: HDAC
Fimepinostat
T2078
Synonym: CUDC-907,PI3K/HDAC Inhibitor,CUDC 907
Target: Apoptosis, PI3K, HDAC
HDAC-IN-26
T39990
Synonym:
Target:
AR42
T6392
Synonym: OSU-HDAC42,AR-42,AR 42,HDAC-42
Target: HDAC
HDAC-IN-5
T11543
Synonym:
Target: HDAC
HDAC-IN-4
T11542
Synonym:
Target: HDAC
PI3K/HDAC-IN-1
T12455
Synonym:
Target: PI3K
HDAC-IN-37
T62708
Synonym:
Target:
HDAC-IN-35
T61916
Synonym:
Target:
HDAC-IN-50
T73179
Synonym:
Target:
HDAC-IN-53
T74783
Synonym:
Target: HDAC
HDAC-IN-43
T62545
Synonym:
Target:
HDAC-IN-44
T63803
Synonym:
Target:
HDAC ligand-1
T79003
Synonym:
Target: HDAC
HDAC-IN-29
T61954
Synonym:
Target:
HDAC-IN-6
T72012
Synonym:
Target:
HDAC-IN-30
T62006
Synonym:
Target:
HDAC-IN-34
T62649
Synonym:
Target:
HDAC-IN-39
T63416
Synonym:
Target:
HDAC-IN-49
T73167
Synonym:
Target:
HDAC-IN-42
T61630
Synonym:
Target:
HDAC-IN-27
T61209
Synonym:
Target:
HDAC-IN-61
T79541
Synonym:
Target: HDAC
HDAC-IN-62
T79371
Synonym:
Target: Autophagy
HDAC-IN-59
T78766
Synonym:
Target: HDAC
HDAC-IN-47
T62072
Synonym:
Target:
HDAC-IN-60
T78767
Synonym:
Target: HDAC
HDAC-IN-32
T61248
Synonym:
Target:
HDAC-IN-58
T78920
Synonym:
Target: HDAC
HDAC-IN-9
T63696
Synonym:
Target:
HDAC-IN-28
T62799
Synonym:
Target:
HDAC-IN-36
T63791
Synonym:
Target:
HDAC-IN-46
T62514
Synonym:
Target:
HDAC-IN-38
T62920
Synonym:
Target:
HDAC-IN-41
T62644
Synonym:
Target:
HDAC-IN-31
T62109
Synonym:
Target:
HDAC-IN-45
T63422
Synonym:
Target:
HDAC-IN-33
T61429
Synonym:
Target:
HDAC-IN-63
T78818
Synonym:
Target:
HDAC-IN-55
T78532
Synonym:
Target: Others
HDAC-IN-64
T79674
Synonym:
Target: HDAC
1 2 3 4 5 6 7
Cat No. Product Name Synonyms Targets
TQ0207 Sulforaphane Apoptosis , Nrf2 , HDAC
Sulforaphane is derived from the consumption of cruciferous vegetables, such as broccoli. It has shown anticancer and cardioprotective activities.
T7052 Gnetol Tyrosinase , COX , HDAC , AChR
Gnetol competitivity inhibits butyrylcholinesterase (IC50: 1.3 uM). Gnetol has a strong inhibitory effect on murine tyrosinase activity. Gnetol significantly suppresses melanin biosynthesis in murine B16 melanoma cells. ...
T2266 SantacruzaMate A CAY-10683 HDAC
SantacruzaMate A (CAY-10683) is a potent and selective HDAC inhibitor.
T6270 Trichostatin A TSA HDAC
Trichostatin A (TSA) is a natural derivative of diene isohydroxamic acids. Trichostatin A is a histone deacetylase inhibitor (IC50=1.8 nM) that is reversible and specific. Trichostatin A leads to the hyperacetylation of ...
TN1911 Marein transporter , Akt , HDAC , AMPK
Marein shows neuroprotective effect on PC12 cell damage induced by methylglyoxal, which is due to a reduction of damage to mitochondria function and activation of the AMPK signal pathway, it may be a potent compound for ...
T3753 Sinapinic Acid Sinapic acid,Synapoic acid Apoptosis , RAAS , Reactive Oxygen Species , HDAC
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinap...
T6S0033 Crotonoside Isoguanosine,2-HYDROXYADENOSINE Others , FLT , HDAC
1. Crotonoside (Isoguanosine) has much more active than adenosine in reducing the blood pressure in rabbits and cats, in decreasing the tone of isolated intestinal strips of the rabbit, guinea pig and hamster and in stim...
T7064 Valproic Acid Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid Mitophagy , Gamma-secretase , HIV Protease , GABA Receptor , Sodium Channel , HDAC , Autophagy
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that inhibits HDAC1 activity, induces HDAC2 degradation, and is orally active. Valproic Acid can be used in epilepsy and bipolar disorder research.
T19687 Phenylethyl isothiocyanate JC 5411,JC5411,JC-5411 HDAC
Phenylethyl isothiocyanate (JC5411) is an HDAC inhibitor. It potentially for the treatment of benign prostatic hypertrophy.
T14305 Apicidin OSI 2040 Apoptosis , HDAC , Autophagy
Apicidin (OSI 2040) is a histone deacetylase (HDAC) inhibitor with antiparasitic activity and antiproliferative activity.Apicidin attenuates memory deficits, inhibits cell growth and proliferation, and induces apoptosis ...
T2140 Parthenolide (-)-Parthenolide Apoptosis , Mitophagy , NF-κB , HDAC , Autophagy
(-)-Parthenolide ((-)-Parthenolide), an inhibitor of the Nuclear Factor-κB Pathway, also promotes the ubiquitination of MDM2 and activates p53 cellular functions.
TN4220 Homobutein 3-O-Methylbutein,2',4,4'-Trihydroxy-3-methoxychalcone Antioxidant , NF-κB , HDAC , Parasite , Immunology/Inflammation related
Homobutein (3-O-Methylbutein) is a dual inhibitor of HDACs and NF-κB with IC50s of 190 and 38 μM. Homobutein is an iron chelator with anticancer, anti-inflammatory, antiparasite, and antioxidation activities.
T36797 1-Alaninechlamydocin
1-Alaninechalmydocin is a fungal metabolite originally isolated from a Great Lakes-derived Tolypocladium sp. and an inhibitor of histone deacetylases (HDACs). It reduces total HDAC activity in HeLa cell lysates in a conc...
T36303 Psammaplin A
Psammaplin A, a marine metabolite, functions as a robust inhibitor of HDAC and DNA methyltransferases, displaying notable potency and selectivity as a DAC1 inhibitor, with an IC50 value of 0.9 nM. It exhibits antimicrobi...
T70778 Depudecin
Depudecin is a polyketide obtained from the fungus Alternaria brassicicola and having a highly unusual structure of an 11-carbon chain containing two epoxides and six stereogenic centres. It is an inhibitor of histone de...
TN2095 Pomiferin NOS , NF-κB , PDE
Pomiferin is a natural product inhibitor of carbonic anhydrase I and II isoenzymes. It has anticancer, antibacterial and antidiabetic properties. Pomiferin has anti-inflammatory and neuroprotective activities.

Natural Products

Sulforaphane
TQ0207
Synonym:
Target: Apoptosis, Nrf2, HDAC
Gnetol
T7052
Synonym:
Target: Tyrosinase, COX, HDAC, AChR
SantacruzaMate A
T2266
Synonym: CAY-10683
Target: HDAC
Trichostatin A
T6270
Synonym: TSA
Target: HDAC
Marein
TN1911
Synonym:
Target: transporter, Akt, HDAC, AMPK
Sinapinic Acid
T3753
Synonym: Sinapic acid,Synapoic acid
Target: Apoptosis, RAAS, Reactive Oxygen Species, HDAC
Crotonoside
T6S0033
Synonym: Isoguanosine,2-HYDROXYADENOSINE
Target: Others, FLT, HDAC
Valproic Acid
T7064
Synonym: Sodium valproate,2-Propylpentanoic Acid,VPA,Depakine,2-Propylvaleric Acid
Target: Mitophagy, Gamma-secretase, HIV Protease, GABA Receptor, Sodium Channel, HDAC, Autophagy
Phenylethyl isothiocyanate
T19687
Synonym: JC 5411,JC5411,JC-5411
Target: HDAC
Apicidin
T14305
Synonym: OSI 2040
Target: Apoptosis, HDAC, Autophagy
Parthenolide
T2140
Synonym: (-)-Parthenolide
Target: Apoptosis, Mitophagy, NF-κB, HDAC, Autophagy
Homobutein
TN4220
Synonym: 3-O-Methylbutein,2',4,4'-Trihydroxy-3-methoxychalcone
Target: Antioxidant, NF-κB, HDAC, Parasite, Immunology/Inflammation related
1-Alaninechlamydocin
T36797
Synonym:
Target:
Psammaplin A
T36303
Synonym:
Target:
Depudecin
T70778
Synonym:
Target:
Pomiferin
TN2095
Synonym:
Target: NOS, NF-κB, PDE

Recombinant Proteins

Species：
Human (14)
Mouse (2)
Expression System：
E. coli (9)
Baculovirus-Insect Cells (6)
Yeast (1)
Tag：
N-terminal 6xHis-tagged (5)
His (3)
GST (2)
N-terminal 6xHis-SUMO-tagged (2)
His,GST (1)
N-terminal 6xHis-Avi-tagged (1)
N-terminal GST-tagged (1)
Tag Free (1)
Cat No. Product Name Species Expression System
TMPY-03431 HDAC4 Protein, Human, Recombinant (aa 612-1084) Human Baculovirus-Insect Cells
HDAC4 (histone deacetylase 4), belongs to class II of the histone deacetylase/AcuC/APhA family. Histone Deacetylases (HDACs) are a group of enzymes closely related to sirtuins. They catalyze the removal of acetyl groups ...
TMPY-01333 HDAC8 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Histone deacetylase 8, also known as HDAC8 and HDACL1, is a nucleus and cytoplasm protein that belongs to the histone deacetylase family and HD type 1 subfamily. Histone deacetylases (HDACs) are a growing family of enzym...
TMPH-01474 HDAC6 Protein, Human, Recombinant (His) Human E. coli
HDAC6 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01476 HDAC9 Protein, Human, Recombinant (His) Human E. coli
HDAC9 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPH-01471 HDAC1 Protein, Human, Recombinant (His & SUMO) Human E. coli
HDAC1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01475 HDAC7 Protein, Human, Recombinant (His) Human E. coli
HDAC7 Protein, Human, Recombinant (His) is expressed in E. coli.
TMPY-02317 HDAC8 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Histone deacetylase 8, also known as HDAC8 and HDACL1, is a nucleus and cytoplasm protein that belongs to the histone deacetylase family and HD type 1 subfamily. Histone deacetylases (HDACs) are a growing family of enzym...
TMPH-01473 HDAC3 Protein, Human, Recombinant (His & SUMO) Human E. coli
HDAC3 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli.
TMPH-01472 HDAC11 Protein, Human, Recombinant (GST) Human E. coli
HDAC11 Protein, Human, Recombinant (GST) is expressed in E. coli.
TMPH-01242 IKZF1 Protein, Human, Recombinant (Avi & His) Human E. coli
Transcription regulator of hematopoietic cell differentiation. Binds gamma-satellite DNA. Plays a role in the development of lymphocytes, B- and T-cells. Binds and activates the enhancer (delta-A element) of the CD3-delt...
TMPY-03056 LSD1 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
LSD1 belongs to the flavin monoamine oxidase family. It contains 1 SWIRM domain and is a component of an RCOR/GFI/LSD1/HDAC complex. LSD1 interacts directly with GFI1 and GFI1B. LSD1 specifically removes histone H3K4me2 ...
TMPY-03283 HBP1 Protein, Human, Recombinant (GST) Human E. coli
HBP1 is a sequence-specific DNA-binding transcription factor. It is involved in many biological processes. It was reported that HBP1 binds to p16(INK4A) promoter and activates p16(INK4A) expression. We found that trichos...
TMPY-01713 RbAp48 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Histone-binding protein RBBP4, also known as Retinoblastoma-binding protein 4, Retinoblastoma-binding protein p48, Chromatin assembly factor 1 subunit C, Chromatin assembly factor I p48 subunit, Nucleosome-remodeling fac...
TMPY-05251 RbAp48 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Histone-binding protein RBBP4, also known as Retinoblastoma-binding protein 4, Retinoblastoma-binding protein p48, Chromatin assembly factor 1 subunit C, Chromatin assembly factor I p48 subunit, Nucleosome-remodeling fac...
TMPH-00841 SMARCA4 Protein, Human, Recombinant (His) Human E. coli
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti...
TMPH-02217 SMARCA4 Protein, Human, Recombinant (His) Human Yeast
Involved in transcriptional activation and repression of select genes by chromatin remodeling (alteration of DNA-nucleosome topology). Component of SWI/SNF chromatin remodeling complexes that carry out key enzymatic acti...
HDAC4 Protein, Human, Recombinant (aa 612-1084)
TMPY-03431
Species: Human
Expression System: Baculovirus-Insect Cells
HDAC8 Protein, Human, Recombinant (GST)
TMPY-01333
Species: Human
Expression System: Baculovirus-Insect Cells
HDAC6 Protein, Human, Recombinant (His)
TMPH-01474
Species: Human
Expression System: E. coli
HDAC9 Protein, Human, Recombinant (His)
TMPH-01476
Species: Human
Expression System: E. coli
HDAC1 Protein, Human, Recombinant (His & SUMO)
TMPH-01471
Species: Human
Expression System: E. coli
HDAC7 Protein, Human, Recombinant (His)
TMPH-01475
Species: Human
Expression System: E. coli
HDAC8 Protein, Mouse, Recombinant (His)
TMPY-02317
Species: Mouse
Expression System: Baculovirus-Insect Cells
HDAC3 Protein, Human, Recombinant (His & SUMO)
TMPH-01473
Species: Human
Expression System: E. coli
HDAC11 Protein, Human, Recombinant (GST)
TMPH-01472
Species: Human
Expression System: E. coli
IKZF1 Protein, Human, Recombinant (Avi & His)
TMPH-01242
Species: Human
Expression System: E. coli
LSD1 Protein, Human, Recombinant (His & GST)
TMPY-03056
Species: Human
Expression System: Baculovirus-Insect Cells
HBP1 Protein, Human, Recombinant (GST)
TMPY-03283
Species: Human
Expression System: E. coli
RbAp48 Protein, Human, Recombinant (His)
TMPY-01713
Species: Human
Expression System: Baculovirus-Insect Cells
RbAp48 Protein, Mouse, Recombinant (His)
TMPY-05251
Species: Mouse
Expression System: Baculovirus-Insect Cells
SMARCA4 Protein, Human, Recombinant (His)
TMPH-00841
Species: Human
Expression System: E. coli
SMARCA4 Protein, Human, Recombinant (His)
TMPH-02217
Species: Human
Expression System: Yeast
Cat No. Product Name
L3400 Clinical Compound Library

3480 compounds
A unique collection of 3480 compounds in clinical trial phases for high throughput screening (HTS) and high content screening (HCS);

Libraries

Clinical Compound Library
L3400
Compounds: 3480
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