Powder: -20°C for 3 years | In solvent: -80°C for 1 year
ACY-957 (HDAC Inhibitor C001) is an orally active and selective inhibitor of HDAC1 and HDAC2 (IC50s: 7 nM, 18 nM, and 1300 nM against HDAC1/2/3) and shows no inhibition on HDAC4/5/6/7/8/9.
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 97.00 | |
5 mg | In stock | $ 255.00 | |
10 mg | In stock | $ 422.00 | |
25 mg | In stock | $ 689.00 | |
50 mg | In stock | $ 981.00 | |
100 mg | In stock | $ 1,350.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 279.00 |
Description | ACY-957 (HDAC Inhibitor C001) is an orally active and selective inhibitor of HDAC1 and HDAC2 (IC50s: 7 nM, 18 nM, and 1300 nM against HDAC1/2/3) and shows no inhibition on HDAC4/5/6/7/8/9. |
Targets&IC50 | HDAC2:18 nM, HDAC3:1300 nM, HDAC1:7 nM |
In vitro | ACY-957 is a selective inhibitor of HDAC1 and HDAC2, with IC50s of 7 nM, 18 nM, and 1300 nM against HDAC1/2/3, respectively, and shows no inhibition on HDAC4/5/6/7/8/9. ACY-957 has an IC50 of 304 nM for HDAC2 in primary hematopoietic progenitors[1]. |
Synonyms | HDAC Inhibitor C001 |
Molecular Weight | 429.54 |
Formula | C24H23N5OS |
CAS No. | 1609389-52-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 76.5 mg/mL (178.1 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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ACY-957 1609389-52-7 Chromatin/Epigenetic DNA Damage/DNA Repair HDAC ACY 957 ACY957 HDAC Inhibitor C001 HDAC Inhibitor C 001 HDAC Inhibitor C-001 inhibitor inhibit