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Search Results for " acl "

Targets

Compounds

Natural Products

Recombinant Proteins

Cat No.	Product Name	Synonyms	Targets
T7121	Sulfaclozine	Sulfachloropyrazine,Sulfachloropyrazine sodium	Antibacterial , Antibiotic , Parasite
	Sulfachloropyrazine sodium(Sulfachloropyrazine) is an antiprotozoal,with antibacterial and anticoccidial effects		Antibacterial , Antibiotic , Parasite
T73689	Daclizumab	Ro 24-7375,Zenapax	IL Receptor
	Daclizumab (Zenapax) is a humanized monoclonal antibody that specifically inhibits the alpha subunit of IL-2R-HA. Daclizumab (Zenapax) can inhibit the binding of IL-2 and IL-2R-HA through specific binding to CD25. Dacliz...		IL Receptor
T1065	Baclofen	Lioresal	GABA Receptor
	Baclofen (Lioresal) is a synthetic chlorophenyl-butanoic acid derivative used to treat spasms due to spinal cord damage and multiple sclerosis, muscle-relaxing Baclofen acts as a gamma-aminobutyric acid (GABA) agonist sp...		GABA Receptor
T11852	Linaclotide		Guanylate cyclase
	Linaclotide developed for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic constipation, and is a potent and selective guanylate cyclase C agonist.		Guanylate cyclase
T72077	Imidacloprid-urea
	Imidacloprid-urea is a secondary metabolite of imidacloprid. Imidacloprid is a potent and widely used neonicotinoid with inhibitory effects on pests of cereals, vegetables, tea and cotton. imidacloprid-urea can occupy or...
T12367	Parsaclisib	INCB050465	PI3K
	Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP)		PI3K
T19533	Pyraclonil		Others
	Pyraclonil, a herbicide agent, effectively controls susceptible (S) and multiple-herbicide-resistant (MHR) E. indica populations as it acts as a proporphyrinogen oxidase (PPO) inhibitor.		Others
T9694	Emraclidine	CVL-231	AChR
	Emraclidine (CVL-231) is a muscarinic M4 receptor positive allosteric modulator and can be used in neurological diseases studies.		AChR
T21371	Apraclonidine hydrochloride	Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum	Adrenergic Receptor
	Apraclonidine hydrochloride (ALO 2145) is an α2-adrenergic agonist and a weak α-1 adrenergic receptor agonist. Apraclonidine hydrochloride lowers intraocular pressure in human eyes and can be used in studies about glauco...		Adrenergic Receptor
T7635	Raclopride		Dopamine Receptor
	Raclopride is a selective antagonist of dopamine D2/D3 receptor.		Dopamine Receptor
T8630	Baclofen hydrochloride	4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride	GABA Receptor
	Baclofen hydrochloride (4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride) is a GAMMA-AMINOBUTYRIC ACID derivative that is a specific GABA-B RECEPTORS agonist. It is used in the treatment of MUSCLE SPASTICITY, espe...		GABA Receptor
T1786	Daclatasvir dihydrochloride	BMS-790052 dihydrochloride	HCV Protease
	Daclatasvir dihydrochloride (BMS-790052 dihydrochloride) is an orally available antiviral agent that inhibits the NS5A region of the hepatitis C virus (HCV) and is used in combination with other oral antiviral agents to ...		HCV Protease
T6229	Daclatasvir	Daklinza,EBP 883,BMS-790052	HCV Protease
	Daclatasvir (EBP 883) (BMS-790052) is a highly selective inhibitor of HCV NS5A with EC50 of 9-50 pM, for a broad range of HCV replicon genotypes and the JFH-1 genotype 2a infectious virus in cell culture. Phase 3.		HCV Protease
T38272	Thiacloprid		AChR , Parasite
	Thiacloprid is a neonicotinoid insecticide that acts as a selective agonist at insect nicotinic acetylcholine receptors (nAChRs) with IC50values of 2.7 and 860 nM forDrosophilanAChRs and M10 mouse fibroblast cells expres...		AChR , Parasite
T6969	Imidacloprid		Others
	Imidacloprid is a systemic chloronicotinyl insecticide, which can be effectively used in agriculture to control pests .		Others
T83653	SACLAC		Apoptosis , Caspase
	SACLAC is a cysteine asparaginase activation inhibitor with antitumor activity that decreases AML cell viability, inhibits AML cell proliferation, increases AML cell death, and induces apoptosis of AML cells, and is used...		Apoptosis , Caspase
T28303	Pazinaclone	A-77000,DN-2327,DN2327,DN 2327,A 77000,A77000	GABA Receptor
	Pazinaclone is a non-benzodiazepine (GABAA) partial agonist with sedative and anxiolytic activity.		GABA Receptor
T8604	Fenaclon	Fenaclonum	Others
	Fenaclon (Fenaclonum) is an anticonvulsant. It is indicated for the treatment of epilepsy.		Others
T2555	Aclidinium bromide	LAS 34273,LAS-W 330	AChR
	Aclidinium bromide (LAS-W 330) is a synthetic anticholinergic agent that is used as an inhalant for treatment of acute bronchospasm due to chronic bronchitis or emphysema. Aclidinium has not been implicated in causing li...		AChR
T9491	Pyraclostrobin		Antibacterial , Antifungal
	Pyraclostrobin is one of the most heavily used fungicides that inhibits mitochondrial complex III of fungal and mammalian cells.		Antibacterial , Antifungal
T1495	Cefaclor monohydrate	Cefaclor,Cefaclorum,Cefachlor	Antibacterial , Antibiotic
	Cefaclor monohydrate (Cefaclorum) is a beta-lactam, second-generation cephalosporin antibiotic with bactericidal activity.		Antibacterial , Antibiotic
T38273	Paclobutrazol	(2R,3R)-Paclobutrazol,(R,R)-paclobutrazol,2R,3R-Paclobutrazol	Antifungal
	Paclobutrazol ((R,R)-paclobutrazol) is a triazole-containing plant growth retardant that is known to inhibit the biosynthesis of gibberellins.1,2It also has antifungal activities.3PBZ, which is transported acropetally in...		Antifungal
T20864	7-Troc-paclitaxel		Others
	7-Troc-paclitaxel is a precursor of paclitaxel which has anti-tumor activity.		Others
T6355	(R)-baclofen	STX209,Arbaclofen	GABA Receptor
	(R)-baclofen (STX209), a derivative of gamma-aminobutyric acid, is commonly utilized for the treatment of spasticity.		GABA Receptor
T4440	Saclofen		GABA Receptor
	Saclofen is a sulfonic analog of the inhibitory neurotransmitter γ-aminobutyric acid (GABA) that acts as a competitive antagonist of the GABAB receptor (IC50: 7.8 μM).1 This compound can be used to determine the function...		GABA Receptor
T2337	BMS-303141	BMS 303141	ATP Citrate Lyase
	BMS-303141 is a potent ATP-citrate lyase (ACL) inhibitor (IC50: 0.13 uM, human recombinant ACL).		ATP Citrate Lyase
T30118	Arbaclofen placarbil	XP 19986,XP19986,XP-19986
	Arbaclofen placarbil( XP19986) is a GABA(B) receptor agonist.Arbaclofen Placarbil is a novel R-baclofen prodrug with improved absorption, distribution, metabolism, and elimination properties compared to R-baclofen. And i...
T23842	Butaclamol free base	Butaclamol,AY 23028,AY 23,028,AY-23028,AY23,028,AY-23,028
	Butaclamol is a typical antipsychotic which was never marketed. It also acts as a dopamine receptor antagonist.
T23617	Aclacinomycin	Aclacinomycins,Siwenmycin
	Aclacinomycin A is an anthracycline drug. It sensitizes K562 chronic myeloid leukemia cells to imatinib through p38MAPK-mediated erythroid differentiation. It is used in the treatment of cancer.
T16953	Sulfaclozine sodium	Sulfachloropyrazine sodium	Antibacterial
	Sulfaclozine sodium is an efficacious sulphonamide derivative with antibacterial and anticoccidial effects. Sulfaclozine sodium is commonly used for the treatment of various poultry diseases.		Antibacterial
T33861	Paclitaxel-MVCP
	Paclitaxel-MVCP ( MC-val-cit-pab-paclitaxel )is a paclitaxel derivative with an MC-Val-Cit-PAB linker, which can be used for the preparation of Paclitaxel conjugates for drug delivery and nanomedicine research.
T20265	Paclitaxel Poliglumex	CT2103,Opaxio,PG-TXL,CT-2103,PPX,CT 2103
	Paclitaxel Poliglumex is cyclohexane isolated from the bark of the Pacific yew tree.
T17306	(R)-Baclofen hydrochloride	Arbaclofen hydrochloride	GABA Receptor
	Arbaclofen hydrochloride, a Gamma-Aminobutyric Acid derivative, is a specific agonist of GABA-B receptors, it is used to treat spasticity, especially that due to spinal cord damage. It acts at spinal and supraspinal site...		GABA Receptor
T39490	Aclimostat	ZGN-1061,Aclimostat
	Aclimostat (ZGN-1061) is a highly potent inhibitor of the MetAP2 enzyme that demonstrates promising efficacy and safety profiles in preclinical trials. In a mouse model of obesity and insulin resistance, ZGN-1061 exhibit...
T74006	Daclatasvir Impurity B
	Daclatasvir Impurity B, a noted impurity of the antiviral agent Daclatasvir, acts as a potent inhibitor of the HCV NS5A protein [1].
T60350	Apraclonidine
	Apraclonidine (ALO 2145) is a selective α2 and weak α1 receptor agonist that effectively lowers intraocular pressure (IOP) in human eyes. Apraclonidine is a topical ophthalmic solution [1] [2].
T34769	Taclamine hydrochloride	AY-22,214,AY 22214
	Taclamine hydrochloride is a biochemical with minor sedative properties.
T26553	Aclatonium Napadisilate	Acaltonium napadisilate
	Aclatonium Napadisilate, a cholinergic agonist, has been shown to stimulates endocrine and exocrine pancreatic secretion.
T60238	Acloproxalap
	Acloproxalap is a quinoline-based aldehyde scavenger that can be used in studies of diseases with toxic aldehyde accumulation, such as inflammatory diseases of the eye and skin, respiratory diseases such as pneumonia, or...
T74007	Daclatasvir Impurity C
	Daclatasvir Impurity C is an impurity found in Daclatasvir, a robust inhibitor of the HCV NS5A protein [1].
T70728	Vadaclidine
	Vadaclidine is an orally acting antinociceptive muscarinic agonist.
T36896	6α-hydroxy Paclitaxel	6alpha-hydroxypaclitaxel	Drug Metabolite
	6α-hydroxy Paclitaxel (6α-OH-PTX) is a major metabolite of the anticancer compound paclitaxel and is partially cytotoxic.		Drug Metabolite
T22495	2-Hydroxysaclofen		Others
	2-Hydroxysaclofen is a GABAB receptor antagonist.		Others
T29102	Vedaclidine tartrate
	Vedaclidine tartrate is a muscarinic analgesic.
T29611	Acluracil
	Acluracil is a biochemical.
T20962	(S)-Baclofen	(+)-Baclofen,(L)-Baclofen
	(S)-Baclofen has effects on excitation in the ascending auditory pathway leading to it a potential reagent for the treatment of hyperactive auditory disorders such as hyperacusis and tinnitus.
T68219	Peraclopone
	Peraclopone is a hypolidemic drug. It is an inhibitor of 7-Dehydrocholesterol reductase. Peraclopone potently inhibits the final step in cholesterol biosynthesis. Feeding this agent to rats leads to a rapid replacement o...
T28297	Parsaclisib hydrochloride	Parsaclisib HCl,INCB-50465,INCB 050465,INCB-050465,INCB050465 HCl,INCB 50465,INCB50465 HCl	PI3K
	Parsaclisib hydrochloride (INCB050465 HCl) is a selectve PI3Kδ inhibitor with antitumor activity. Parsaclisib demonstrates potent activity with IC50 values ranging from 0.2 to 2 nM.		PI3K
T7635L	Raclopride tartrate	FLA 870,FLA-870,FLA870
	Raclopride is a selective antagonist on D2 dopamine receptor ( D2 Ki: 1.8 nm, D3 Ki: 3.5 nm, D4 Ki: 2400, D1 Ki: 18000 nM).
T17357	AcLys-PABC-VC-Aur0101		Others
	AcLys-PABC-VC-Aur0101 is a drug-linker conjugate for anti-CXCR4 ADC with potent antitumor activity, comprising the auristatin microtubule inhibitor Aur0101, connected through the cleavable linker AcLys-PABC-VC[1].		Others

Compounds

Sulfaclozine

T7121

Synonym: Sulfachloropyrazine,Sulfachloropyrazine sodium

Target: Antibacterial, Antibiotic, Parasite

Daclizumab

T73689

Synonym: Ro 24-7375,Zenapax

Target: GABA Receptor

Linaclotide

T11852

Synonym:

Target: Guanylate cyclase

Apraclonidine hydrochloride

T21371

Synonym: Iopidine,ALO 2145,Apraclonidina,P-aminoclonidine,4-Aminoclonidine,Apraclonidine HCl,Apraclonidinum

Target: Adrenergic Receptor

Raclopride

T7635

Synonym:

Target: Dopamine Receptor

Baclofen hydrochloride

T8630

Synonym: 4-amino-3-(4-chlorophenyl)butanoic acid hydron chloride

Target: GABA Receptor

Daclatasvir dihydrochloride

T1786

Synonym: BMS-790052 dihydrochloride

Target: HCV Protease

Daclatasvir

T6229

Synonym: Daklinza,EBP 883,BMS-790052

Target: AChR, Parasite

Target: Apoptosis, Caspase

Pazinaclone

T28303

Synonym: A-77000,DN-2327,DN2327,DN 2327,A 77000,A77000

Target: GABA Receptor

Synonym: LAS 34273,LAS-W 330

Target: Antibacterial, Antifungal

Cefaclor monohydrate

T1495

Synonym: Cefaclor,Cefaclorum,Cefachlor

Target: Antibacterial, Antibiotic

Paclobutrazol

T38273

Synonym: (2R,3R)-Paclobutrazol,(R,R)-paclobutrazol,2R,3R-Paclobutrazol

Synonym: STX209,Arbaclofen

Target: GABA Receptor

Saclofen

T4440

Synonym:

Target: GABA Receptor

BMS-303141

T2337

Synonym: BMS 303141

Target: ATP Citrate Lyase

Arbaclofen placarbil

T30118

Synonym: XP 19986,XP19986,XP-19986

Target:

Butaclamol free base

T23842

Synonym: Butaclamol,AY 23028,AY 23,028,AY-23028,AY23,028,AY-23,028

Target:

Aclacinomycin

T23617

Synonym: Aclacinomycins,Siwenmycin

Target:

Sulfaclozine sodium

T16953

Synonym: Sulfachloropyrazine sodium

Target: Antibacterial

Paclitaxel Poliglumex

T20265

Synonym: CT2103,Opaxio,PG-TXL,CT-2103,PPX,CT 2103

Target:

(R)-Baclofen hydrochloride

T17306

Synonym: Arbaclofen hydrochloride

Target: GABA Receptor

Aclimostat

T39490

Synonym: ZGN-1061,Aclimostat

Target:

Daclatasvir Impurity B

Taclamine hydrochloride

T34769

Synonym: AY-22,214,AY 22214

Target:

Aclatonium Napadisilate

T26553

Synonym: Acaltonium napadisilate

Daclatasvir Impurity C

6α-hydroxy Paclitaxel

T36896

Synonym: 6alpha-hydroxypaclitaxel

Target: Drug Metabolite

Synonym: (+)-Baclofen,(L)-Baclofen

Parsaclisib hydrochloride

T28297

Synonym: Parsaclisib HCl,INCB-50465,INCB 050465,INCB-050465,INCB050465 HCl,INCB 50465,INCB50465 HCl

Target: PI3K

Raclopride tartrate

T7635L

Synonym: FLA 870,FLA-870,FLA870

Target:

AcLys-PABC-VC-Aur0101

T17357

Synonym:

Target: Others

Cat No.	Product Name	Synonyms	Targets
TL0013	Heraclenin		Anti-infection , Immunology/Inflammation related
	Heraclenin has anticoagulant, and anti-inflammatory activities, it also has mutagenicity in Chlamydomonas reinhardii. Heraclenin can induce apoptosis in Jurkat leukemia cells, it has a strong clastogenic effect . (+)-Her...		Anti-infection , Immunology/Inflammation related
T5738	7-Epi 10-desacetyl paclitaxel	10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol	Others
	7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) shows IC50 values of 0.085 nM, against HeLa cells.		Others
T0968	Paclitaxel	Taxol,NSC 125973	Apoptosis , Microtubule Associated , Autophagy
	Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.		Apoptosis , Microtubule Associated , Autophagy
T5749	10-Deacetyl-7-xylosyl paclitaxel	10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,10-Deacetylpaclitaxel 7-Xyloside	Others , Microtubule Associated
	10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) is a Paclitaxel derivative with improved pharmacological features and higher water solubility,used in Chinese clinics to treat cancer.		Others , Microtubule Associated
T20578	Maclurin	Fustic extract,Morintannic acid,NSC 83240	Free radical scavengers , Reactive Oxygen Species
	Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of ...		Free radical scavengers , Reactive Oxygen Species
T21502	Aclacinomycin A
	Aclacinomycin A has a wide range of applications in life science related research.
TN1730	Heraclenol		Antibacterial
	Heraclenol is derived from the fruits of Angelica lucida with antibacterial activities. Heraclenol is a germination inhibitor in the parsley and lettuce seeds.		Antibacterial
TN4203	Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside]		Others
	Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside] is a natural product for research related to life sciences. The catalog number is TN4203 and the CAS number is 765316-44-7.		Others
T10238	Aclacinomycin A hydrochloride	Aclarubicin hydrochloride	Proteasome
	Aclacinomycin A (Aclarubicin) hydrochloride is a fluorescent molecule and the first described non-peptidic inhibitor showing discrete specificity for the CTRL (chymotrypsin-like) activity of the 20S proteasome. Aclacinom...		Proteasome
T73913	Fumigaclavine A
	Fumigaclavine A, a clavine alkaloid mycotoxin produced by Aspergillus fumigatus, can be isolated from mold-contaminated silage [1].
TN4204	Heraclenol 3'-O-beta-D-glucopyranoside		Others
	Heraclenol 3'-O-beta-D-glucopyranoside is a natural product for research related to life sciences. The catalog number is TN4204 and the CAS number is 32207-10-6.		Others
TN4202	(-)-Heraclenol		Antifection
	(-)-Heraclenol shows in vitro anti-plasmodial activity against chloroquine-sensitive and chloroquine-resistant strains of Plasmodium falciparum.(-)-Heraclenol has moderate antibacterial and antifungal activities.		Antifection
TN5912	Macluraxanthone	3-Hydroxyblancoxanthone	Antioxidant , TNF
	Macluraxanthone (3-Hydroxyblancoxanthone) has many biological activities including anticholinesterase, antioxidant, anticancer, antimalarial, anti-inflammatory and immunomodulatory effects. macluraxanthone promotes the p...		Antioxidant , TNF
T80015	(±)-Heraclenol
	(±)-Heraclenol, a coumarin derivative isolated from the fruits of Angelica lucida, exhibits antibacterial properties [1].
TN4205	Heraclenol acetonide		Others
	Heraclenol acetonide is a natural product for research related to life sciences. The catalog number is TN4205 and the CAS number is 64790-68-7.		Others
T79936	Forrestiacids K		ATP Citrate Lyase
	Forrestiacid K, a terpenoid derived from Pseudotsuga forrestii, functions as an inhibitor of ATP-citrate lyase (ACL) [1].		ATP Citrate Lyase
T79935	Forrestiacids J		ATP Citrate Lyase
	Forrestiacid J is an inhibitor of ATP-citrate lyase (ACL), exhibiting an IC50 value of 2.6 μM [1].		ATP Citrate Lyase

Natural Products

Heraclenin

TL0013

Synonym:

Target: Anti-infection, Immunology/Inflammation related

7-Epi 10-desacetyl paclitaxel

T5738

Synonym: 10-Deacetyl-7-epipaclitaxel,7-Epi-10-deacetyltaxol

Target: Others

Paclitaxel

T0968

Synonym: Taxol,NSC 125973

Target: Apoptosis, Microtubule Associated, Autophagy

10-Deacetyl-7-xylosyl paclitaxel

T5749

Synonym: 10-Deacetyl-7-xylosyltaxol,10-Deacetyltaxol 7-Xyloside,7-Xylosyl-10-deacetyltaxol,10-Deacetylpaclitaxel 7-Xyloside

Target: Others, Microtubule Associated

Maclurin

T20578

Synonym: Fustic extract,Morintannic acid,NSC 83240

Target: Free radical scavengers, Reactive Oxygen Species

Target: Antibacterial

Heraclenol 3'-O-[beta-D-apiofuranosyl-(1-6)-beta-D-glucopyranoside]

TN4203

Synonym:

Target: Others

Aclacinomycin A hydrochloride

T10238

Synonym: Aclarubicin hydrochloride

Heraclenol 3'-O-beta-D-glucopyranoside

Synonym: 3-Hydroxyblancoxanthone

Target: Antioxidant, TNF

Target: ATP Citrate Lyase

Forrestiacids J

T79935

Synonym:

Target: ATP Citrate Lyase

Recombinant Proteins

Species：

Expression System：

Tag：

Cat No.	Product Name	Species	Expression System
TMPY-02483	ATP citrate lyase/ACLY Protein, Human, Recombinant (His)	Human	Baculovirus Insect Cells
	ATP citrate lyase, also known as Acly or Acl, is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is composed of two polymer chains which are polypeptides in human. ATP...
TMPH-00320	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His)	Calloselasma rhodostoma	P. pastoris (Yeast)
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00323	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His & Myc)	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00321	Snaclec rhodocytin subunit alpha Protein, Calloselasma rhodostoma, Recombinant (His & SUMO)	Calloselasma rhodostoma	E. coli
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...
TMPH-00322	Snaclec rhodocytin subunit beta Protein, Calloselasma rhodostoma, Recombinant (His)	Calloselasma rhodostoma	P. pastoris (Yeast)
	Elicits platelet aggregation by the binding to the C-type lectin domain family 1 member B (CLEC1B/CLEC2). Binding leads to tyrosine phosphorylation in the cytoplasmic tail of CLEC1B, which promotes the binding of spleen ...