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Maclurin

Catalog No. T20578 CAS 519-34-6

Synonyms: Fustic extract, Morintannic acid, NSC 83240

Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of many diseases or MSCs transplantation.

All products from TargetMol are for Research Use Only. Not for Human or Veterinary or Therapeutic Use.

Maclurin, CAS 519-34-6

Pack Size	Availability	Price/USD
5 mg	In stock	$ 50.00
10 mg	In stock	$ 70.00
25 mg	In stock	$ 114.00
50 mg	In stock	$ 167.00
100 mg	In stock	$ 248.00
1 mL * 10 mM (in DMSO)	In stock	$ 58.00

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Biological Description

Chemical Properties

Storage & Solubility Information

Description	Maclurin (NSC-83240) is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of many diseases or MSCs transplantation.
In vitro	Maclurin effectively protects against mesenchymal stem cells (MSCs) oxidative damage induced by hydroxyl radical (OH) at 62.1-310.5 μM. Maclurin efficiently protects DNA from OH-induced damage at 114.6-382.2 μM, and scavenge OH, DPPH, ABTS(+), and bind Cu(2+) with IC50s of 122.87, 10.15, 0.97, and 133.95 μM[1].

Synonyms	Fustic extract, Morintannic acid, NSC 83240
Molecular Weight	262.21
Formula	C13H10O6
CAS No.	519-34-6

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: 4.8 mg/mL (18.31 mM)

References and Literature

1. Li X, et al. Maclurin protects against hydroxyl radical-induced damages to mesenchymal stem cells: antioxidant evaluation and mechanistic insight. Chem Biol Interact. 2014 Aug 5;219:221-8. 2. Ku MJ, et al. Maclurin suppresses migration and invasion of human non-small-cell lung cancer cells via anti-oxidative activity and inhibition of the Src/FAK-ERK-β-catenin pathway. Mol Cell Biochem. 2015 Apr;402(1-2):243-52. 3. Lee YJ, Lee SY. Maclurin exerts anti-cancer effects in human osteosarcoma cells via prooxidative activity and modulations of PARP, p38, and ERK signaling. IUBMB Life. 2021 Aug;73(8):1060-1072. 4. Kim J, et al. Protective Effects of Maclurin against Benzo[a]pyrene via Aryl Hydrocarbon Receptor and Nuclear Factor Erythroid 2-Related Factor 2 Targeting. Antioxidants (Basel). 2021 Jul 26;10(8):1189.

Related compound libraries

This product is contained In the following compound libraries：

Tobacco Monomer Library Natural Product Library for HTS Anti-Prostate Cancer Compound Library Traditional Chinese Medicine Monomer Library Anti-Ovarian Cancer Compound Library Anti-Breast Cancer Compound Library Mitochondria-Targeted Compound Library Metabolism Compound Library Selected Plant-Sourced Compound Library Anti-Cancer Compound Library

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Keywords

Maclurin 519-34-6 Immunology/Inflammation Metabolism NF-Κb oxidation-reduction Free radical scavengers Reactive Oxygen Species NSC83240 Fustic extract NSC-83240 Morintannic acid NSC 83240 inhibitor inhibit

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