Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP)
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
1 mg | In stock | $ 148.00 | |
5 mg | In stock | $ 322.00 | |
10 mg | In stock | $ 522.00 | |
25 mg | In stock | $ 848.00 | |
50 mg | In stock | $ 1,170.00 | |
100 mg | In stock | $ 1,580.00 | |
1 mL * 10 mM (in DMSO) | In stock | $ 353.00 |
Description | Parsaclisib (INCB050465) is a potent and selective inhibitor of PI3Kδ(IC50 of 1 nM at 1 mM ATP) |
Targets&IC50 | PI3Kδ:1 nM (at 1 mM ATP) |
In vitro | Parsaclisib displays significant activity with IC50 values ranging from 0.2 to 2 nM in B and T cell proliferation aaasys. Parsaclisib inhibits proliferation of several DLBCL and MCL cell lines in vitro (EC50 < 10 nM)[1]. |
Synonyms | INCB050465 |
Molecular Weight | 432.88 |
Formula | C20H22ClFN6O2 |
CAS No. | 1426698-88-5 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 122 mg/mL (281.83 mM), Sonication is recommended.
You can also refer to dose conversion for different animals. More
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc.
Parsaclisib 1426698-88-5 PI3K/Akt/mTOR signaling PI3K inhibit INCB-050465 INCB050465 INCB 050465 Phosphoinositide 3-kinase relapsed refractory malignancies Inhibitor PI3Kδ B-cell inhibitor