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Paclitaxel Poliglumex

Catalog No. T20265   CAS 263351-82-2
Synonyms: CT2103, Opaxio, PG-TXL, CT-2103, PPX, CT 2103

Paclitaxel Poliglumex is cyclohexane isolated from the bark of the Pacific yew tree.

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Paclitaxel Poliglumex Chemical Structure
Paclitaxel Poliglumex, CAS 263351-82-2
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Biological Description
Chemical Properties
Storage & Solubility Information
Description Paclitaxel Poliglumex is cyclohexane isolated from the bark of the Pacific yew tree.
Synonyms CT2103, Opaxio, PG-TXL, CT-2103, PPX, CT 2103
Molecular Weight 1001.04
Formula C52H60N2O18
CAS No. 263351-82-2

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year

Solubility Information

DMSO: Soluble

TargetMolReferences and Literature

1. Markovsky E, Eldar-Boock A, Ben-Shushan D, Baabur-Cohen H, Yeini E, Pisarevsky E, Many A, Aviel-Ronen S, Barshack I, Satchi-Fainaro R. Targeting NCAM-expressing neuroblastoma with polymeric precision nanomedicine. J Control Release. 2017 Mar 10;249:162-172. doi: 10.1016/j.jconrel.2017.01.044. Epub 2017 Feb 1. PubMed PMID: 28159518. 2. Elinzano H, Glantz M, Mrugala M, Kesari S, Piccioni DE, Kim L, Pan E, Yunus S, Coyle T, Timothy K, Evans D, Mantripragada K, Boxerman J, DiPetrillo T, Donahue JE, Hebda N, Mitchell KM, Rosati KL, Safran H. PPX and Concurrent Radiation for Newly Diagnosed Glioblastoma Without MGMT Methylation: A Randomized Phase II Study: BrUOG 244. Am J Clin Oncol. 2018 Feb;41(2):159-162. doi: 10.1097/COC.0000000000000247. PubMed PMID: 26658237. 3. Chow W, Amaya CN, Rains S, Chow M, Dickerson EB, Bryan BA. Growth Attenuation of Cutaneous Angiosarcoma With Propranolol-Mediated β-Blockade. JAMA Dermatol. 2015 Nov;151(11):1226-9. doi: 10.1001/jamadermatol.2015.2554. PubMed PMID: 26375166. 4. Boxerman JL, Ellingson BM, Jeyapalan S, Elinzano H, Harris RJ, Rogg JM, Pope WB, Safran H. Longitudinal DSC-MRI for Distinguishing Tumor Recurrence From Pseudoprogression in Patients With a High-grade Glioma. Am J Clin Oncol. 2017 Jun;40(3):228-234. doi: 10.1097/COC.0000000000000156. PubMed PMID: 25436828.

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Keywords

Paclitaxel Poliglumex 263351-82-2 CT2103 Opaxio PG-TXL CT-2103 PPX CT 2103 inhibitor inhibit

 

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