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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T0803 | Acetrizoic acid | Urokon,Opacaron,Acetrizoesaeure | Others |
Acetrizoic acid (Urokon) is the first monomeric ionic compound used as an X-ray contrast agent. | |||
T5373 | Acrizanib | LHA510 | VEGFR |
Acrizanib (LHA510) is a VEGFR-2 inhibitor, with an IC50 of 17.4 nM for BaF3-VEGFR-2. | |||
T34782 | Tamolarizine | Tamolarizine,Tamolarizine HCl,Tamolarizine free base,NC 1100,NC1100,Tamolarizine dihyrchloride,NC-1100 | Calcium Channel |
Tamolarizine (Tamolarizine free base) free base is a novel calcium antagonist. | |||
T9550 | Drometrizole Trisiloxane | Mexoryl XL,Silatrizole | Others |
Drometrizole Trisiloxane (Mexoryl XL) is a photostable UVA and UVB light filter. | |||
T0806 | Flunarizine dihydrochloride | Flunarizine 2HCl,KW-3149,R14950 | Calcium Channel , Dopamine Receptor , Sodium Channel |
Flunarizine dihydrochloride (R14950) is a selective calcium entry blocker with calmodulin binding properties and histamine H1 blocking activity. Flunarizine dihydrochloride (R14950) is effective in the prophylaxis of mig... | |||
T22354 | Levocetirizine Dihydrochloride | Xyzal Dihydrochloride,(-)-Cetirizine Dihydrochloride | Histamine Receptor |
Levocetirizine Dihydrochloride (Xyzal Dihydrochloride) is a third-generation peripheral H1-receptor antagonist. Acting as an antihistaminic agent, it specifically targets the histamine H1-receptor. Levocetirizine Dihydro... | |||
T6357 | (S)-crizotinib | ent-crizotinib | Apoptosis , DNA/RNA Synthesis , MTH1 |
(S)-crizotinib (ent-crizotinib) (IC50 of 72 nM), an effective MTH1 (NUDT1) inhibitor, is the (S)-enantiomer of crizotinib. | |||
T1661 | Crizotinib | PF-02341066 | c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase |
Crizotinib (PF-02341066) is an ATP-competitive small-molecule tyrosine kinases inhibitor of c-MET (IC50: 8 nM) and ALK (IC50: 20 nM) receptor. | |||
T70044 | Sarizotan HCl | EMD 128130 HCl | Dopamine Receptor , 5-HT Receptor , HER |
Sarizotan HCl (EMD 128130 HCl) is an orally active 5-HT1A receptor and dopamine receptor agonist and hERG channel inhibitor with antidepressant activity for the study of movement disorders in Parkinson;s disease. | |||
T28922 | Taprizosin | Taprizosin Mesylate,UK-338003,UK-338,003,UK338003,UK 338003 | Adrenergic Receptor |
Taprizosin(UK-338003) is a selective and orally active α1-adrenoceptor antagonist for vasodilatation in the treatment of benign prostatic hyperplasia. | |||
T1469 | Levocetirizine | Levocetirizine HCl | Histamine Receptor |
Levocetirizine is a Histamine-1 Receptor Antagonist. The mechanism of action of levocetirizine is as a Histamine H1 Receptor Antagonist. | |||
T14303 | Alrizomadlin | APG-115,AA-115 | Mdm2 |
Alrizomadlin (APG-115) is an orally active inhibitor of MDM2 with IC50 of 3.8 nM and Ki of 1 nM, respectively[1]. Alrizomadlin blocks the interaction of MDM2 and p53 and induces cell-cycle arrest and apoptosis in a p53-d... | |||
T0089 | Cetirizine dihydrochloride | P071,UCB P071,Cetirizine DiHCl | Histamine Receptor |
Cetirizine dihydrochloride (UCB P071) is an effective second-generation histamine H1 antagonist that is potent in the therapy of allergic rhinitis, confirmed urticaria, and pollen-induced asthma. Unlike other conventiona... | |||
T1395 | Diatrizoic Acid | Diatrizoate,Amidotrizoic acid | Apoptosis , Others |
Diatrizoic Acid (Amidotrizoic acid) is an organic, iodinated radiopaque X-ray contrast medium used in diagnostic radiography. | |||
T77399 | Crizanlizumab | ADAKVEO,SEG-101 | Others |
Crizanlizumab (Adakveo) is a humanized monoclonal antibody against P-selectin for the prevention of pain crises in sickle cell disease. | |||
T27830 | Lifarizine | RS 87476,RS 87476-000,RS-87476,RS-87476-000,RS87476 | Calcium Channel |
Lifarizine (RS-87476), a calcium-sodium channel antagonist, shows neuroprotective activity in a simplified rat survival model of double vessel occlusion. | |||
T27830L | Lifarizine FA | Lifarizine FA(119514-66-8 Free base) | Sodium Channel |
Lifarizine FA is a sodium channel blocker used in the treatment of neurological disorders and cardiovascular diseases, study of stroke. | |||
T77647 | Tubulin polymerization-IN-43 | Apoptosis , Microtubule Associated | |
Tubulin polymerization-IN-43 is an inhibitor of tubulin polymerisation.Tubulin polymerization-IN-43 has multiple effects, disrupting the cellular microtubule network by targeting the colchicine locus and promoting cell c... | |||
T9084 | Cetirizine Impurity B dihydrochloride | De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride | Histamine Receptor |
Cetirizine Impurity B dihydrochloride (De(carboxymethoxy) Cetirizine Acetic Acid Dihydrochloride) is an impurity of Cetirizine dihydrochloride. Cetirizine is a second-generation antihistamine. Cetirizine is a specific, o... | |||
T70044L | Sarizotan 2HCl | ||
T31821 | Fluorizoline | Apoptosis | |
Fluorizoline is a PHB-binding compound with anticancer and antiproliferative activity that induces apoptosis by inducing selective targeting of the BH3 protein NOXA to PHB.Fluorizoline inhibits protein synthesis and has ... | |||
T0340 | Bisoctrizole | Tinosorb M,UV-360,Milestab-360,Tinuvin-360 | Others |
Bisoctrizole (Tinosorb M) is a benzotriazole-based organic compound that is added to sunscreens to absorb UV rays. | |||
T65013 | Cuprizone | Others | |
Cuprizone is a copper chelator.Cuprizone is used to induce schizophrenia in mice.Cuprizone induces oligodendrocyte death and induces a demyelination response. | |||
T0903 | Cinnarizine | Stugeron,Cinarizine,Dimitronal,Stutgin | Calcium Channel , Histamine Receptor |
Cinnarizine (Stugeron) is a piperazine derivative having histamine H1-receptor and calcium-channel blocking activity with vasodilating and antiemetic properties but it induces PARKINSONIAN DISORDERS. | |||
T27244 | Efletirizine | UCB 28754,UCB-28754,UCB28754 | Lipoxygenase , Histamine Receptor |
Efletirizine (UCB-28754) is a histamine receptor antagonist with inhibitory effects on the enzyme 5-lipoxygenase (5-LO), and is useful in the topical treatment of allergic diseases. | |||
T77728 | Tubulin polymerization-IN-55 | Microtubule Associated | |
Tubulin polymerization-IN-55 is a potent Tubulin Polymerization inhibitor with potential anti-angiogenic and anti-tumour activity, showing anti-proliferative effects against A549, K562, HepG2, MDA-MB-231 and HFL-1. | |||
T9045 | Bemotrizinol | Others | |
Bemotrizinol is a UVA absorber used as a topical sunscreen. | |||
T6571 | Lomerizine dihydrochloride | Terranas,Lomerizine 2HCl,Lomerizine hydrochloride,KB-2796 | Calcium Channel |
Lomerizine dihydrochloride (KB-2796) is an antagonist of L- and T-type voltage-gated calcium channels used to treat migraine. | |||
T19641 | Epirizole | DA 398,Mepirizole,DA398,Mebron,Methopyrimazole,Dalex,DA-398 | Others |
Epirizole (Mebron) shows antipyretic, analgesic, and anti-inflammatory activity and can be used in studies about chronic rheumatoid arthritis. | |||
T1512 | Rizatriptan benzoate | MK-462 Benzoate | 5-HT Receptor |
Rizatriptan benzoate (MK-462 Benzoate) selectively binds to and activates serotonin (5-HT) 1B receptors and 5-HT 1D receptors providing relief of migraine headaches. | |||
T8399 | Crizotinib hydrochloride | PF-02341066 hydrochloride | c-Met/HGFR , ROS , ALK , Autophagy , ROS Kinase |
Crizotinib hydrochloride (PF-02341066 hydrochloride) is a novel inhibitor of anaplastic lymphoma kinase and c-Met(IC50s of 20 and 8 nM) | |||
T77651 | Tubulin polymerization-IN-47 | Microtubule Associated | |
Tubulin polymerization-IN-47 is a tubulin polymerization inhibitor and mitotic inhibitor with antitumor activity and inhibitory effects on neuroblastoma cancer cell proliferation, with IC50s of 7 and 12 nM for Chp-134 an... | |||
T1319 | Sodium diatrizoate | Diatrizoic acid sodium salt,Sodium amidotrizoate,Hypaque sodium,Diatrizoate sodium,amidotrizoate sodium,Triombrin | Apoptosis , Others |
Sodium diatrizoate (Hypaque sodium) is an iodinated radiopaque X-ray contrast medium. This contrast agent is used as a diagnostic aid in angiography, urography and radiography.It can induce mitochondrial renewal and oxid... | |||
T20637 | Diatrizoate meglumine | Reno,Renografin,Renovist,Hypaque,Renocal,Sinografin | Others |
Diatrizoate meglumine (Renocal) is the meglumine salt of diatrizoate, it is an organic, iodinated, radiopaque X-ray contrast medium used in diagnostic radiography. | |||
T63849 | Tubulin polymerization-IN-34 | ||
Tubulin polymerization-IN-34 is an inhibitor of [1,2] oxazolylisoindole microtubulin polymerization and is highly selective for marginal zone lymphoma VL51 cell lines. | |||
T29592 | Acetrizoate sodium | Reopak,Diaginol,MP1023,MP 1023,MP-1023 | |
Acetrizoate sodium, known as the sodium salt of acetrizoic acid,can be used as a high-osmolality, water-soluble, iodinated radiographic contrast medium. | |||
T63725 | Tubulin polymerization-IN-35 | ||
Tubulin polymerization-IN-35 is [1,2] an inhibitor of oxazolylisoindole microtubulin polymerization that acts highly selectively on the marginal zone lymphoma VL51 cell line. | |||
T82049 | IR-Crizotinib | NF-κB | |
IR-Crizotinib is a conjugate of the near-infrared dye IR-786 and Crizotinib, an NF-κB-inducing kinase (NIK) inhibitor, with an IC50 of 3.381 μM for intracranial glioblastoma (GBM) localization in mice. It has the ability... | |||
T25722 | Lifarizine methanesulfonate | ||
Lifarizine methanesulfonate is a modulator of sodium-calcium channel that reduces ischemic brain damage. | |||
T60802 | Tubulin polymerization-IN-2 | ||
Tubulin Polymerization-IN-2 is a powerful anticancer agent that targets β-tubulin, exhibiting an IC 50 of 0.92 μM. It demonstrates promising efficacy against a range of cancer cell lines including leukemia, non-small cel... | |||
T73981 | Deschloro Cetirizine dihydrochloride | ||
Deschloro Cetirizine Dihydrochloride is an impurity of Cetirizine, a second-generation antihistamine and the carboxylated metabolite of hydroxyzine. It functions as a specific, orally active, and long-acting histamine H1... | |||
T19234 | Cetirizine D8 dihydrochloride | Histamine Receptor | |
Cetirizine D8 dihydrochloride is a deuterium-labeled Cetirizine. Cetirizine is a second-generation antihistamine and a long-acting histamine H1-receptor antagonist. | |||
T79429 | Tubulin polymerization-IN-50 | ||
Tubulin Polymerization-IN-50 (compound 7n) serves as an inhibitor of tubulin polymerization, exhibiting an IC50 of 5.05 μM in SK-Mel-28 cells and inducing cell cycle arrest at the G2/M phase [1]. | |||
T62693 | Tubulin polymerization-IN-29 | ||
Tubulin polymerization-IN-29 is a potent inhibitor of microtubule protein polymerization and shows potent anti-proliferative effects.Tubulin polymerization-IN-29 induces cell cycle arrest in HeLa cells at G2/M phase. | |||
T35882 | Rizatriptan N-oxide | ||
Rizatriptan N-oxide is a potential impurity found in commercial preparations of rizatriptan.1It is a degradation product formed under oxidative conditions. | |||
T63836 | Tubulin polymerization-IN-7 | ||
Tubulin aggregation-IN-7 is a potent tubulin aggregation inhibitor that has shown research potential for cancer diseases. | |||
T79532 | Tubulin polymerization-IN-44 | ||
Tubulinpolymer-in-44 (compound 7w) effectively inhibits Tubulin with an IC50 value of 0.21 μM and induces apoptosis by arresting the G2/M phase, making it useful for cancer research. | |||
T79341 | Tubulin polymerization-IN-45 | ||
Tubulin polymerization-IN-45, a tubulin-targeting agent, acts as a tubulin polymerization inhibitor by binding to the tubulin's colchicine site. It induces apoptotic cell death in hepatocellular cancer (HCC) cells [1]. | |||
T79629 | Tubulin polymerization-IN-46 | ||
Tubulin polymerization-IN-46 (compound 9q) is a microtubule/tubulin inhibitor that impedes tubulin polymerization, induces apoptosis, and arrests MCF-7 breast cancer cells in the G2/M phase, exhibiting potent anti-prolif... | |||
T79766 | Tubulin polymerization-IN-52 | ||
Tubulin polymerization-IN-52 (compound SC23) effectively inhibits tubulin polymerization, exhibiting an IC50 value of 2.9 μM [1]. |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T2922 | Phlorizin | Floridzin,NSC 2833,Phloridzin | ATPase , SGLT |
Phlorizin (Phloridzin) is a non-selective SGLT inhibitor found in apple, for hSGLT1( Ki=300 nM) and hSGLT2( Ki=39 nM) . | |||
T16012 | Marizomib | NPI-0052,Salinosporamide A,ML858 | Proteasome |
Marizomib (ML858) is a novel irreversible brain-permeable proteasome inhibitor that inhibits CT-L (β5), CT-T-laspase-like (C-L, β1), and trypsin-like (T-L, β2) 20S proteasomes with IC50s of 3.5, 28, and 430 nM, respectiv... | |||
T2S2003 | Phlorizin dihydrate | Phloridzin dihydrate | Others |
1. Phlorizin dihydrate (Phloridzin dihydrate) can significantly inhibit oxidative DNA damage. |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01265 | RIZ1 Protein, Human, Recombinant (GST) | Human | E. coli |
RIZ1 Protein, Human, Recombinant (GST) is expressed in E. coli expression system with GST tag. The predicted molecular weight is 49.6 kDa and the accession number is Q13029-1. | |||
TMPY-01272 | RIZ1 Protein, Human, Recombinant | Human | E. coli |
RIZ1 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 23 kDa and the accession number is Q13029-1. | |||
TMPY-01469 | Frizzled 5 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Frizzled 5 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.6 kDa and the accession number is Q13467. | |||
TMPJ-01331 | Frizzled-8 Protein, Human, Recombinant (His & Avi), Biotinylated | Human | HEK293 Cells |
Frizzled-8 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-6xHis-Avi tag. The predicted molecular weight is 25-35 KDa and the accession number is Q9H461. | |||
TMPY-01797 | Frizzled 10 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Frizzled 10 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is Q149J3. | |||
TMPY-03293 | Frizzled 5 Protein, Mouse, Recombinant (hFc) | Mouse | CHO Cells |
Frizzled 5 Protein, Mouse, Recombinant (hFc) is expressed in CHO mammalian cells with hFc tag. The predicted molecular weight is 42.9 kDa and the accession number is Q9EQD0. | |||
TMPY-04633 | Frizzled 2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
FZD2 may be a tumor suppressor gene in salivary adenoid cystic carcinomas (SACCs) that inhibits cell growth and migration. OMOD2 is a rare skeletal dysplasia and characterized by facial dysmorphism and shortness of the u... | |||
TMPY-00313 | Frizzled 4 Protein, Rat, Recombinant (His) | Rat | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EV... | |||
TMPY-06697 | FZD3/frizzled 3 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
FZD3/frizzled 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.79 kDa and the accession number is Q9NPG1-1. | |||
TMPY-01165 | FZD1/Frizzled 1 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-term... | |||
TMPY-00577 | Frizzled 6 Protein, Human, Recombinant (mFc) | Human | HEK293 Cells |
Frizzled 6 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42 kDa and the accession number is A0A024R9E9. | |||
TMPH-00817 | Pectate lyase 1 Protein, Hesperocyparis arizonica, Recombinant (His & Myc) | Hesperocyparis arizonica | E. coli |
Has pectate lyase activity. Pectate lyase 1 Protein, Hesperocyparis arizonica, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 42.6 kDa and... | |||
TMPJ-00354 | FZD1/Frizzled 1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 Cells |
Frizzled homolog 1 (FZD1), also known as Frizzled-1, a member of the G-protein-coupled receptor superfamily, mediates Wnt signaling by serving as a co-receptor with LRP-5 for Wnt ligands. The FZD1 protein contains a sign... | |||
TMPH-01193 | Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His) | HHV-5 | E. coli |
Human cytomegalovirus (HCMV) (strain AD169) Uncharacterized protein UL128 (His) is expressed in E. coli. | |||
TMPY-04147 | Frizzled 10 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Frizzled 10 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.5 kDa and the accession number is Q9ULW2. | |||
TMPY-05933 | Influenza A H1N1 (A/Arizona/13/2008) Neuraminidase/NA (His) | H1N1 | HEK293 Cells |
Influenza A H1N1 (A/Arizona/13/2008) Neuraminidase/NA (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50.3 kDa and the accession number is B9W3K0. | |||
TMPY-04302 | Frizzled 4 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EV... | |||
TMPY-05489 | Frizzled 5 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Frizzled 5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.7 kDa and the accession number is Q13467. | |||
TMPY-03310 | Frizzled 4 Protein, Rat, Recombinant (hFc) | Rat | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EV... | |||
TMPY-04140 | Frizzled 10 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Frizzled 10 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.8 kDa and the accession number is Q9ULW2. | |||
TMPY-00197 | Frizzled 4 Protein, Human, Recombinant (hFc) | Human | HEK293 Cells |
Familial exudative vitreoretinopathy (FEVR) is a hereditary blinding disorder that features defects in retinal vascular development. Mutations in FZD4 are known to cause autosomal dominant exudative vitreoretinopathy (EV... | |||
TMPY-01798 | Frizzled 10 Protein, Mouse, Recombinant (His) | Mouse | HEK293 Cells |
Frizzled 10 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.4 kDa and the accession number is Q149J3. | |||
TMPY-04271 | Frizzled 6 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Frizzled 6 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.1 kDa and the accession number is A0A024R9E9. | |||
TMPJ-01332 | Frizzled-8 Protein, Human, Recombinant (His) | Human | HEK293 Cells |
Frizzled-8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 22-32 KDa and the accession number is Q9H461. |