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Search Result

Search Results for " naf "

Targets

PDE

116

Compounds

8

Natural Products

6

Recombinant Proteins

Cat No. Product Name Synonyms Targets
T16079 Mirodenafil SK3530 PDE
Mirodenafil is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
T4992 Cefamandole nafate Cephamandole nafate,Cefamandole formate sodium Antibacterial , Antibiotic
Cefamandole nafate (Cephamandole nafate) is a second-generation broad-spectrum cephalosporin antibiotic.
T2392 Nafamostat mesylate FUT-175 Apoptosis , Serine/threonin kinase , SARS-CoV , Serine Protease
Nafamostat mesylate (FUT-175), a synthetic serine protease inhibitor, has been used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.
T33581 Nafetolol K 5407,K-5407 Others
Nafetolol (K 5407) is a biochemical reagent that can be used to synthesize other compounds.
T15381 Gisadenafil UK-369003 PDE
Gisadenafil (UK-369003) is a selective inhibitor of phosphodiesterase 5 (PDE5) with an IC50 of 3.6 nM and prevents degradation of cGMP.
T68112 Nafimidone
Nafimidone shows anticonvulsant activity in a rat model of amygdala epilepsy and can be used in the treatment of chronic intractable epilepsy.
T1081 Naftidrofuryl oxalate Nafronyl oxalate,Nafronyl oxalate salt 5-HT Receptor
Naftidrofuryl oxalate (Nafronyl oxalate) is a drug used in the management of peripheral and cerebral vascular disorders. It is claimed to enhance cellular oxidative capacity and to be a spasmolytic. It may also be an ant...
T0696 Naftopidil KT-611,BM-15275 Adrenergic Receptor
Naftopidil (KT-611) (INN, marketed under the brand name Flivas), an antihypertensive medicine, is used as a selective α1-adrenergic receptor antagonist or α-blocker.
T1094 Tolnaftate Tonoftal,Sporiline,Tinactin,NP-27 Hedgehog/Smoothened , Antifungal
Tolnaftate (NP-27) is a synthetic antifungal agent.
T1543 Naftifine hydrochloride Naftifungin,Naftifine HCl,Naftin,Exoderil Hedgehog/Smoothened , Antibiotic , Antifungal
Naftifine Hydrochloride is the hydrochloride salt form of naftifine, an allylamine derivate with synthetic broad-spectrum antifungal activity. Although the exact mechanism through which naftifine hydrochloride exerts its...
T14219 Aminaftone Aminaphthone Endothelin Receptor
Aminaftone, a derivative of 4-aminobenzoic acid, inhibits endothelin-1 (ET-1) production and can be used to study hypertension and systemic sclerosis.
T6302 Lonafarnib Sarasar,Sch66336 Raf , Transferase , Autophagy , Ras
Lonafarnib (Sch66336) is an orally bioavailable FPTase inhibitor for H-ras, K-ras-4B, and N-ras (IC50: 1.9/5.2/2.8 nM).
T8919 Homo Sildenafil PDE
Homo Sildenafil is an analog of Sildenafil, It acts as a phosphodiesterase inhibitor.
T21387L Nafoxidine Estrogen Receptor/ERR
Nafoxidine is an estrogen antagonist that has been used in the treatment of breast cancer.
T10634 Bunaftide Bunaphtide,Meregon,Bunaftine Others
Bunaftide (Bunaphtid) has antiarrhythmic effects and inhibits aconitine-induced ventricular tachycardia.
T7346 Lodenafil Hydroxyhomosildenafil PDE
Lodenafil (Hydroxyhomosildenafil) is a potent PDE5 inhibitor, with treatment of erectile dysfunction (ED)
T1497 Liranaftate Piritetrate,M-732 Antifungal
Liranaftate (Piritetrate) is a thiocarbamate and squalene epoxidase inhibitor with antifungal activity. Liranaftate inhibits fungal squalene epoxidase, an enzyme that plays a key role in the synthesis of sterol which is ...
T6336 Amonafide NSC308847,AS1413,Nafidimide,AS1413,Quinamed Topoisomerase
Amonafide (NSC-308847,AS1413)(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage.
T6983 Sildenafil Mesylate PDE
Sildenafil Mesylate is a mesylate form of Sildenafil, an inhibitor of Phosphodiesterase 5.
T1312 Nafcillin sodium monohydrate CL 8491,nafcillin sodium Antibacterial , Antibiotic
Nafcillin sodium monohydrate (CL 8491) is the sodium salt form of nafcillin, a semi-synthetic naphthalene, penicillin-related Nafcillin inhibits bacterial wall synthesis by a mechanism of action similar to penicillin. Pe...
T6653 Salmeterol Xinafoate Salmetedur,GR 33343X xinafoate,Arial HIV Protease , Adrenergic Receptor
Salmeterol Xinafoate (GR 33343X xinafoate) is a long-acting β2-adrenergic receptor agonist with anti-inflammatory effects, used in the treatment of asthma symptoms and chronic obstructive pulmonary disease (COPD) symptom...
T4097 Vardenafil hydrochloride trihydrate Vardenafil HCl Trihydrate,BAY38-9456 PDE
Vardenafil hydrochloride trihydrate (BAY38-9456) is a new type PDE inhibitor with IC50 of 0.7 and 180 nM for PDE5 and PDE1, respectively.
T2334 Avanafil TA1790 PDE
Avanafil (TA1790) is a selective inhibitor of phosphodiesterase type 5 (PDE5) and is used as therapy of erectile dysfunction.
T1217 Butenafine hydrochloride KP363 (Hydrochloride),Butenafine HCl,KP-363 Antibiotic , Antifungal
Butenafine hydrochloride (KP363 Hydrochloride) is a synthetic benzylamine antifungal, inhibiting the synthesis of sterols by inhibiting squalene epoxidase.
T0096 Vardenafil Vivanza,Levitra,Vardenafil hydrochloride PDE
Vardenafil (Vivanza) is an oral therapy for the treatment of erectile dysfunction. It is a selective inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5). Penile erection is a hemod...
T8405 Vardenafil hydrochloride PDE
Vardenafil hydrochloride is a New Phosphodiesterase Type 5(PDE5) Inhibitor, in the Treatment of Erectile Dysfunction in Men With Diabetes
T10758L Centanafadine hydrochloride EB-1020 hydrochloride Dopamine Receptor , Serotonin Transporter , Adrenergic Receptor , Norepinephrine
Centanafadine hydrochloride (EB-1020 hydrochloride) is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin...
T21309 Nafarelin acetate(76932-56-4 free base) RS-94991-298,Nafarelin acetate,Nafarelin acetate hydrate,Synarel GNRH Receptor
Nafarelin acetate(76932-56-4 free base) (RS-94991-298) is a GnRH agonist that acts as an analog of GnRH. Nafarelin acetate(76932-56-4 free base) causes a decrease in the pituitary secretion of gonadotropins luteinizing h...
TQ0126 Mirodenafil dihydrochloride SK-3530 dihydrochloride PDE
Mirodenafil dihydrochloride is a PDE-5 inhibitor developed for the treatment of erectile dysfunction.
T6600 Naftopidil dihydrochloride KT-611,KT-611 2HCl,Naftopidil DiHCl 5-HT Receptor , Adrenergic Receptor
Naftopidil dihydrochloride (KT-611 2HCl) is a selective 5-HT1A and α1-adrenergic receptor antagonist with IC50 of 0.1 μM and 0.2 μM, respectively.
T36061 N-Desmethyl Sildenafil Desmethylsildenafil,UK-103,320 Drug Metabolite
N-Desmethyl Sildenafil (UK-103,320) (Desmethylsildenafil) is a prominent metabolite of Sildenafil, a potent inhibitor of phosphodiesterase type 5 (PDE5).
T8471 Vonafexor EYP001,PLX007,pxl007 FXR , HBV
Vonafexor (EYP001) is a farnesoid X receptor (FXR, NR1H4) agonist, with anti-HBV effects
T25817 Mitonafide NSC-300288,NSC300288,NSC 300288 Antibacterial
Mitonafide (NSC-300288) suppresses the activity of M. tuberculosis NAD+ dependent DNA ligase A. Mitonafide is a DNA intercalating agent.
T10676 Carbodenafil PDE
Carbodenafil is a Sildenafil related compound found in healthy foods. Sildenafil is a PDE5 inhibitor (IC50: 5.22 nM).
T68061 Elinafide
Elinafide, a dinaphthylimide cytotoxic agent, is a DNA-targeted anticancer agent that has shown antitumor activity in in vitro and in vivo assays.
T1283 Clinafloxacin PD 127391,CI-960,AM-1091 Antibacterial , Antibiotic
Clinafloxacin (CI-960)(PD-127391) is a fluoroquinolone antibiotic.
T8877 Bonafton Bonaphthone Antiviral
Bonafton (Bonaphthone) is an antiviral agent.
T0467 Sildenafil citrate UK-92480 citrate Apoptosis , PDE , Autophagy
Sildenafil citrate (UK-92480 citrate) , a cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase type 5 (PDE5) Inhibitor, is used extensively for erectile dysfunction and less commonly for pulmonary hypertensio...
T9220 Naftopidil hydrochloride 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,KT-611 hydrochloride,BM-15275 hydrochloride Adrenergic Receptor
Naftopidil hydrochloride (BM-15275 hydrochloride) is a selective alpha1-adrenoceptor antagonist with Ki of 3.7 nM, 20 nM and 1.2 nM for the cloned human α1a-adrenoceptor, α1b-adrenoceptor and α1d-adrenoceptor, respective...
T33762 Fosifloxuridine nafalbenamide NUC-3373,NUC3373,NUC 3373 DNA/RNA Synthesis
Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher c...
T71658 Indacaterol xinafoate
Indacaterol xinafoate is an ultra-long-acting beta-adrenoceptor agonist.
T69117 Pinafide
Pinafide is a rodenticide and anti-protozoal agent. Pinafide shows strong cytostatic activity against both HeLa and KB cells and is moderately toxic to both mice and rats. It has been proved active against experimental t...
T71519 Chlorodenafil
Chlorodenafil is a related compound of Sildenafil -- a phosphodiesterase inhibitor.
T37181 Avanafil metabolite M4 Avanafil metabolite M4
Avanafil metabolite M4 is a major active metabolite of the phosphodiesterase 5 (PDE5) inhibitor avanafil . Avanafil is metabolized by the cytochrome P450 (CYP450) isoforms CYP3A4 and CYP2C to the major metabolites avanaf...
T19200 Azonafide-PEABA Others
Azonafide-PEABA is a drug moiety with cytotoxic [1].
T10758 Centanafadine EB-1020 Others
Centanafadine is a dual inhibitor of norepinephrine (NE)/dopamine (DA) transporter, also inhibits serotonin transporter (IC50s: 6 nM, 38 nM, and 83 nM for human NE, DA, and serotonin transporter).
T27156 Dexnafenodone Hydrochloride LU43706,LU 43706,Dexnafenodone HCl,LU-43706
Dexnafenodone Hydrochloride is an adrenergic receptor antagonist and serotonin uptake inhibitor.
T70630 Dichlorodenafil
Dichlorodenafil is an inhibitor of phosphodiesterase type 5 enzyme (PDE-5).
T75294 Nafcillin sodium
Nafcillin sodium, an antibiotic, acts as a reversible inhibitor of β-lactamase, making it effective for research into staphylococcal infections [1] [2].
T20159 Bilanafos Herby,Bialaphos,Antibiotic SF 1293
Bilanafos is an agent of Anti-Bacterial.

Compounds

Mirodenafil
T16079
Synonym: SK3530
Target: PDE
Cefamandole nafate
T4992
Synonym: Cephamandole nafate,Cefamandole formate sodium
Target: Antibacterial, Antibiotic
Nafamostat mesylate
T2392
Synonym: FUT-175
Target: Apoptosis, Serine/threonin kinase, SARS-CoV, Serine Protease
Nafetolol
T33581
Synonym: K 5407,K-5407
Target: Others
Gisadenafil
T15381
Synonym: UK-369003
Target: PDE
Nafimidone
T68112
Synonym:
Target:
Naftidrofuryl oxalate
T1081
Synonym: Nafronyl oxalate,Nafronyl oxalate salt
Target: 5-HT Receptor
Naftopidil
T0696
Synonym: KT-611,BM-15275
Target: Adrenergic Receptor
Tolnaftate
T1094
Synonym: Tonoftal,Sporiline,Tinactin,NP-27
Target: Hedgehog/Smoothened, Antifungal
Naftifine hydrochloride
T1543
Synonym: Naftifungin,Naftifine HCl,Naftin,Exoderil
Target: Hedgehog/Smoothened, Antibiotic, Antifungal
Aminaftone
T14219
Synonym: Aminaphthone
Target: Endothelin Receptor
Lonafarnib
T6302
Synonym: Sarasar,Sch66336
Target: Raf, Transferase, Autophagy, Ras
Homo Sildenafil
T8919
Synonym:
Target: PDE
Nafoxidine
T21387L
Synonym:
Target: Estrogen Receptor/ERR
Bunaftide
T10634
Synonym: Bunaphtide,Meregon,Bunaftine
Target: Others
Lodenafil
T7346
Synonym: Hydroxyhomosildenafil
Target: PDE
Liranaftate
T1497
Synonym: Piritetrate,M-732
Target: Antifungal
Amonafide
T6336
Synonym: NSC308847,AS1413,Nafidimide,AS1413,Quinamed
Target: Topoisomerase
Sildenafil Mesylate
T6983
Synonym:
Target: PDE
Nafcillin sodium monohydrate
T1312
Synonym: CL 8491,nafcillin sodium
Target: Antibacterial, Antibiotic
Salmeterol Xinafoate
T6653
Synonym: Salmetedur,GR 33343X xinafoate,Arial
Target: HIV Protease, Adrenergic Receptor
Vardenafil hydrochloride trihydrate
T4097
Synonym: Vardenafil HCl Trihydrate,BAY38-9456
Target: PDE
Avanafil
T2334
Synonym: TA1790
Target: PDE
Butenafine hydrochloride
T1217
Synonym: KP363 (Hydrochloride),Butenafine HCl,KP-363
Target: Antibiotic, Antifungal
Vardenafil
T0096
Synonym: Vivanza,Levitra,Vardenafil hydrochloride
Target: PDE
Vardenafil hydrochloride
T8405
Synonym:
Target: PDE
Centanafadine hydrochloride
T10758L
Synonym: EB-1020 hydrochloride
Target: Dopamine Receptor, Serotonin Transporter, Adrenergic Receptor, Norepinephrine
Nafarelin acetate(76932-56-4 free base)
T21309
Synonym: RS-94991-298,Nafarelin acetate,Nafarelin acetate hydrate,Synarel
Target: GNRH Receptor
Mirodenafil dihydrochloride
TQ0126
Synonym: SK-3530 dihydrochloride
Target: PDE
Naftopidil dihydrochloride
T6600
Synonym: KT-611,KT-611 2HCl,Naftopidil DiHCl
Target: 5-HT Receptor, Adrenergic Receptor
N-Desmethyl Sildenafil
T36061
Synonym: Desmethylsildenafil,UK-103,320
Target: Drug Metabolite
Vonafexor
T8471
Synonym: EYP001,PLX007,pxl007
Target: FXR, HBV
Mitonafide
T25817
Synonym: NSC-300288,NSC300288,NSC 300288
Target: Antibacterial
Carbodenafil
T10676
Synonym:
Target: PDE
Elinafide
T68061
Synonym:
Target:
Clinafloxacin
T1283
Synonym: PD 127391,CI-960,AM-1091
Target: Antibacterial, Antibiotic
Bonafton
T8877
Synonym: Bonaphthone
Target: Antiviral
Sildenafil citrate
T0467
Synonym: UK-92480 citrate
Target: Apoptosis, PDE, Autophagy
Naftopidil hydrochloride
T9220
Synonym: 1-[4-(2-methoxyphenyl)piperazin-1-yl]-3-,KT-611 hydrochloride,BM-15275 hydrochloride
Target: Adrenergic Receptor
Fosifloxuridine nafalbenamide
T33762
Synonym: NUC-3373,NUC3373,NUC 3373
Target: DNA/RNA Synthesis
Indacaterol xinafoate
T71658
Synonym:
Target:
Pinafide
T69117
Synonym:
Target:
Chlorodenafil
T71519
Synonym:
Target:
Avanafil metabolite M4
T37181
Synonym: Avanafil metabolite M4
Target:
Azonafide-PEABA
T19200
Synonym:
Target: Others
Centanafadine
T10758
Synonym: EB-1020
Target: Others
Dexnafenodone Hydrochloride
T27156
Synonym: LU43706,LU 43706,Dexnafenodone HCl,LU-43706
Target:
Dichlorodenafil
T70630
Synonym:
Target:
Nafcillin sodium
T75294
Synonym:
Target:
Bilanafos
T20159
Synonym: Herby,Bialaphos,Antibiotic SF 1293
Target:
1 2 3
Cat No. Product Name Synonyms Targets
T17199 Udenafil PDE
Udenafil is an inhibitor of PDE5 .
T1411 Terbinafine hydrochloride KWD 2019,Terbinafine HCl,TDT 067 hydrochloride Antibacterial , Antibiotic , Antifungal
Terbinafine hydrochloride (KWD 2019) is a synthetic allylamine derivative structurally related to naftifine. Terbinafine is active against dermatophytes.
T6702 Terbinafine Terbinex,SF 86-327,Lamisil,TDT 067 Antibacterial , Antibiotic , Antifungal
Terbinafine (TDT 067) is a synthetic allylamine derivative with antifungal activity. Terbinafine exerts its effect through inhibition of squalene epoxidase, thereby blocking the biosynthesis of ergosterol, an important c...
TN3880 Dodonaflavonol Others
Dodonaflavonol is a natural product for research related to life sciences. The catalog number is TN3880 and the CAS number is 1392213-93-2.
T5156 2,3,2'',3''-Tetrahydroochnaflavone Others
2,3,2'',3''-Tetrahydroochnaflavone is a natural product of Lonicera, Caprifoliaceae. The catalog number is T5156 and the CAS number is 678138-59-5. 2,3,2'',3''-Tetrahydroochnaflavone can be used as a reference standard.
TN1283 4'-O-Methylochnaflavone Others
4'-O-Methylochnaflavone is a natural product
TN5494 2'',3''-Dihydroochnaflavone
2'',3''-Dihydroochnaflavone is a natural product for research related to life sciences. The catalog number is TN5494 and the CAS number is 340997-02-6.
TN5501 Ochnaflavone
Ochnaflavone is a natural product for research related to life sciences. The catalog number is TN5501 and the CAS number is 50276-96-5.

Natural Products

Udenafil
T17199
Synonym:
Target: PDE
Terbinafine hydrochloride
T1411
Synonym: KWD 2019,Terbinafine HCl,TDT 067 hydrochloride
Target: Antibacterial, Antibiotic, Antifungal
Terbinafine
T6702
Synonym: Terbinex,SF 86-327,Lamisil,TDT 067
Target: Antibacterial, Antibiotic, Antifungal
Dodonaflavonol
TN3880
Synonym:
Target: Others
2,3,2'',3''-Tetrahydroochnaflavone
T5156
Synonym:
Target: Others
4'-O-Methylochnaflavone
TN1283
Synonym:
Target: Others
2'',3''-Dihydroochnaflavone
TN5494
Synonym:
Target:
Ochnaflavone
TN5501
Synonym:
Target:

Recombinant Proteins

Species：
Human (5)
Cynomolgus (1)
Expression System：
HEK293 Cells (4)
E. coli (1)
P. pastoris (Yeast) (1)
Tag：
C-His (2)
Tag Free (2)
hFc (2)
Cat No. Product Name Species Expression System
TMPY-00754 IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) Human HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99) is expressed in HEK293 mammalian cells. The predicted molecular weight is 8 kDa and the accession number is A0A024RDA5.
TMPY-00472 IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) Human E. coli
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99) is expressed in E. coli expression system. The predicted molecular weight is 8.5 kDa and the accession number is A0A024RDA5.
TMPY-04726 IL-8/CXCL8 Protein, Human, Recombinant (His) Human P. pastoris (Yeast)
IL-8/CXCL8 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.8 kDa and the accession number is A0A024RDA5.
TMPY-00755 IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) Human HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 28-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35 kDa and the accession number is A0A024RDA5.
TMPK-00480 IL-8/CXCL8 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
Interleukin-8 (IL-8) has been revealed as a critical regulator of CNS function and development with participation in many CNS disorders including gliomas.Several promising approaches that target directly or indirectly IL...
TMPY-00753 IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc) Human HEK293 Cells
IL-8/CXCL8 Protein, Human, Recombinant (aa 23-99, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 35.6 kDa and the accession number is A0A024RDA5.
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