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Fosifloxuridine nafalbenamide

Fosifloxuridine nafalbenamide
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Purity:95.87%
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Fosifloxuridine nafalbenamide

Catalog No. T33762Cas No. 1332837-31-6
Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher concentrations of FUDR-MP in patients' cells.
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Pack SizePriceAvailabilityQuantity
1 mg$81In Stock
5 mg$163In Stock
10 mg$228In Stock
25 mg$413In Stock
50 mg$579In Stock
100 mg$793In Stock
500 mg$1,630In Stock
1 mL x 10 mM (in DMSO)$222In Stock
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Product Introduction

Bioactivity
Description
Fosifloxuridine nafalbenamide (NUC 3373), a pyrimidine nucleotide analogue, is a Thymidylate synthase inhibitor. NUC-3373 has anticancer activity. NUC-3373 is a ProTide transformation of 5-FU that generates much higher concentrations of FUDR-MP in patients' cells.
AliasNUC-3373, NUC3373, NUC 3373
Chemical Properties
Molecular Weight613.53
FormulaC29H29FN3O9P
Cas No.1332837-31-6
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year
Solubility Information
DMSO: 100 mg/mL (162.99 mM)
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM1.6299 mL8.1496 mL16.2991 mL81.4956 mL
5 mM0.3260 mL1.6299 mL3.2598 mL16.2991 mL
10 mM0.1630 mL0.8150 mL1.6299 mL8.1496 mL
20 mM0.0815 mL0.4075 mL0.8150 mL4.0748 mL
50 mM0.0326 mL0.1630 mL0.3260 mL1.6299 mL
100 mM0.0163 mL0.0815 mL0.1630 mL0.8150 mL

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Mother liquor preparation method: 2 mg of drug dissolved in 50 μLDMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μLDMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μLTween 80, mix well and clarify, then add 600 more μLddH2OTargetMol | reagent mix well and clarify.
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